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The map label for this gene is efp-1

Identifier: 15834753

GI number: 15834753

Start: 164120

End: 164692

Strand: Direct

Name: efp-1

Synonym: TC0133

Alternate gene names: 15834753

Gene position: 164120-164692 (Clockwise)

Preceding gene: 15834751

Following gene: 15834757

Centisome position: 15.3

GC content: 44.68

Gene sequence:

>573_bases
ATGGTTCGTGTAAGCACTAGTGAATTTCGTGTAGGATTGCGAGTTGAGATCGATGGCCAGCCCTATGTAATTTTGCAGAA
TGATTTTGTTAAGCCAGGGAAAGGCCAGGCTTTCAATAGGATCAAAGTTAAAAACTTTTTAACTGGGCGAGTAATAGAAA
AAACATTCAAGTCCGGGGAATCTATAGAAACAGCCGATGTTCGTGAACAGCAGATGCGTCTCTTGTATACGGATCAAGAG
GGGGCTACGTTTATGGATGACGAGACCTTTGAGCAAGAGCTGATTTTTTGGGATAAACTGGAAAACATTCGGCAGTGGTT
GTTAGAGGATACAGTTTACACCTTGGTTCGTTACAATGGGGACGTGATTTCTGTTGAGCCGCCCATTTTCATGGAACTAT
CTATCGCAGAAACTGCTCCAGGGGTTCGTGGAGACACCGCATCGGGCCGAGTACTGAAGCCTGCTACAACAAACACTGGG
GCAAAGATTATGGTCCCTATTTTTATTGAAGAGGGTGAAGTTGTGAAGGTGGATACGCGGACAGGGAGTTATGAGTCTCG
CGTATCAAAATAA

Upstream 100 bases:

>100_bases
TTTTATAAGAAGAAAGAGTTAGTTTTGCGACATTCTTCTGGACAAAGCTTAGGAGAGAACGATAACATGGATCGAGAAAA
GATAACGGGTTAAGCGTATT

Downstream 100 bases:

>100_bases
TTAAAAGGGGCGTTAAGCCCCTTCTTTAAGAAGGCGTTCTGCAACTTTCCGAAATAAATGCGAAGGTTCGGGAGCGTCTT
TTATTTCTAAATAATCTCTT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P 2 [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MVRVSTSEFRVGLRVEIDGQPYVILQNDFVKPGKGQAFNRIKVKNFLTGRVIEKTFKSGESIETADVREQQMRLLYTDQE
GATFMDDETFEQELIFWDKLENIRQWLLEDTVYTLVRYNGDVISVEPPIFMELSIAETAPGVRGDTASGRVLKPATTNTG
AKIMVPIFIEEGEVVKVDTRTGSYESRVSK

Sequences:

>Translated_190_residues
MVRVSTSEFRVGLRVEIDGQPYVILQNDFVKPGKGQAFNRIKVKNFLTGRVIEKTFKSGESIETADVREQQMRLLYTDQE
GATFMDDETFEQELIFWDKLENIRQWLLEDTVYTLVRYNGDVISVEPPIFMELSIAETAPGVRGDTASGRVLKPATTNTG
AKIMVPIFIEEGEVVKVDTRTGSYESRVSK
>Mature_190_residues
MVRVSTSEFRVGLRVEIDGQPYVILQNDFVKPGKGQAFNRIKVKNFLTGRVIEKTFKSGESIETADVREQQMRLLYTDQE
GATFMDDETFEQELIFWDKLENIRQWLLEDTVYTLVRYNGDVISVEPPIFMELSIAETAPGVRGDTASGRVLKPATTNTG
AKIMVPIFIEEGEVVKVDTRTGSYESRVSK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=48.4042553191489, Blast_Score=179, Evalue=9e-47,
Organism=Escherichia coli, GI87082061, Length=187, Percent_Identity=26.2032085561497, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 21551; Mature: 21551

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRVSTSEFRVGLRVEIDGQPYVILQNDFVKPGKGQAFNRIKVKNFLTGRVIEKTFKSGE
CEEECCHHEEEEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCC
SIETADVREQQMRLLYTDQEGATFMDDETFEQELIFWDKLENIRQWLLEDTVYTLVRYNG
CEEHHHHHHHEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECC
DVISVEPPIFMELSIAETAPGVRGDTASGRVLKPATTNTGAKIMVPIFIEEGEVVKVDTR
CEEEECCCEEEEEEEHHCCCCCCCCCCCCCEECCCCCCCCCEEEEEEEECCCCEEEEECC
TGSYESRVSK
CCCCHHHCCC
>Mature Secondary Structure
MVRVSTSEFRVGLRVEIDGQPYVILQNDFVKPGKGQAFNRIKVKNFLTGRVIEKTFKSGE
CEEECCHHEEEEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCC
SIETADVREQQMRLLYTDQEGATFMDDETFEQELIFWDKLENIRQWLLEDTVYTLVRYNG
CEEHHHHHHHEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECC
DVISVEPPIFMELSIAETAPGVRGDTASGRVLKPATTNTGAKIMVPIFIEEGEVVKVDTR
CEEEECCCEEEEEEEHHCCCCCCCCCCCCCEECCCCCCCCCEEEEEEEECCCCEEEEECC
TGSYESRVSK
CCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]