Click here to switch to the map view.

The map label for this gene is mreB

Identifier: 15834707

GI number: 15834707

Start: 98114

End: 99214

Strand: Direct

Name: mreB

Synonym: TC0082

Alternate gene names: 15834707

Gene position: 98114-99214 (Clockwise)

Preceding gene: 15834706

Following gene: 15834708

Centisome position: 9.14

GC content: 43.6

Gene sequence:

>1101_bases
ATGAGCCCACACCGCAGCTTATACAAATTTAAAAACTTTTCTAATCGCCTATATAACAAGGCTTTAGGTCGTTTTGATCG
TGTATTTAATTTTTTTTCCGGGAATGTTGGCATTGATCTAGGTACTGCAAATACCTTGGTTTATGTACGTGGACGAGGGA
TTGTTCTTAGTGAGCCTTCGGTGGTAGCGGTTGATGCTCAGACTCATGCGGTGTTGGCTGTAGGTCATAAAGCAAAGGCT
ATGTTAGGGAAAACTCCCCGGAAAATTGTTGCTGTTCGTCCCATGAAGGACGGAGTCATAGCTGATTTCGAAATAGCAGA
AGGGATGCTCAAAGCGTTAATTAAACGGGTTACCCCTGCTCGTAGTATGTTTCGTCCAAAAATTCTGATCGCAGTGCCAT
CAGGTATTACCGGTGTTGAAAAACGAGCTGTTGAGGATTCTGCGTTACACGCAGGGGCGCAGGAAGTAATTTTGATTGAA
GAGCCTATGGCAGCTGCTATCGGAGTCGATCTTCCGGTGCATGAACCTGCTGCCAGTATGATTATTGATATTGGTGGAGG
AACAACAGAAATTGCCATCATTTCTCTAGGAGGAATTGTTGAATCTCGTTCTTTGCGTATAGCTGGGGATGAGTTCGATG
AGTGCATTATTAATTATATGCGGCGCACATATAATTTGATGATAGGTCCTCGAACTGCGGAAGAAATTAAAATTACCATA
GGTTCTGCGTATCCATTGGGTGATCAAGAGTTGGAAATGGAAGTGCGTGGTCGAGATCAGGTGGCTGGGCTTCCCATTAC
GAAGAGAATCAATTCTGTAGAGATCAGAGAGTGCTTAGCAGAACCCATTCAGCAAATTATAGAGTGTGTACGATTAACTC
TAGAAAAATGTCCTCCAGAACTTTCTGCAGATTTAGTAGAGCGGGGAATGGTGCTGGCTGGAGGTGGAGCTCTTATTAAA
GGGCTGGACAAAGCTTTAAGTAAAAATACAGGGCTTTCTGTTATTACTGCTCCGCATCCGCTTCTAGCGGTTTGCTTAGG
CACAGGGAAAGCTTTGGAACATCTAGATCAATTGAAGAAACGTAAAGAGAGTTTGGTATGA

Upstream 100 bases:

>100_bases
AGGAAAAAGGGTCTTGTAAAGAAAGTGATCAATTCTGATGATGAAGTCGTTTCTAAGTTAACTTGGGAAGAAGTGCTCGA
ACTTCTACAGATATAGTTTT

Downstream 100 bases:

>100_bases
CCGGCGATTGGATGTCTAAGATAACCCATTCAGGATTAAAATCCTGGATAGAGGAGGTGATAGCTTTAGTGTCGCCTAAG
GACGTGAGGTTATGCGATGG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSPHRSLYKFKNFSNRLYNKALGRFDRVFNFFSGNVGIDLGTANTLVYVRGRGIVLSEPSVVAVDAQTHAVLAVGHKAKA
MLGKTPRKIVAVRPMKDGVIADFEIAEGMLKALIKRVTPARSMFRPKILIAVPSGITGVEKRAVEDSALHAGAQEVILIE
EPMAAAIGVDLPVHEPAASMIIDIGGGTTEIAIISLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITI
GSAYPLGDQELEMEVRGRDQVAGLPITKRINSVEIRECLAEPIQQIIECVRLTLEKCPPELSADLVERGMVLAGGGALIK
GLDKALSKNTGLSVITAPHPLLAVCLGTGKALEHLDQLKKRKESLV

Sequences:

>Translated_366_residues
MSPHRSLYKFKNFSNRLYNKALGRFDRVFNFFSGNVGIDLGTANTLVYVRGRGIVLSEPSVVAVDAQTHAVLAVGHKAKA
MLGKTPRKIVAVRPMKDGVIADFEIAEGMLKALIKRVTPARSMFRPKILIAVPSGITGVEKRAVEDSALHAGAQEVILIE
EPMAAAIGVDLPVHEPAASMIIDIGGGTTEIAIISLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITI
GSAYPLGDQELEMEVRGRDQVAGLPITKRINSVEIRECLAEPIQQIIECVRLTLEKCPPELSADLVERGMVLAGGGALIK
GLDKALSKNTGLSVITAPHPLLAVCLGTGKALEHLDQLKKRKESLV
>Mature_365_residues
SPHRSLYKFKNFSNRLYNKALGRFDRVFNFFSGNVGIDLGTANTLVYVRGRGIVLSEPSVVAVDAQTHAVLAVGHKAKAM
LGKTPRKIVAVRPMKDGVIADFEIAEGMLKALIKRVTPARSMFRPKILIAVPSGITGVEKRAVEDSALHAGAQEVILIEE
PMAAAIGVDLPVHEPAASMIIDIGGGTTEIAIISLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITIG
SAYPLGDQELEMEVRGRDQVAGLPITKRINSVEIRECLAEPIQQIIECVRLTLEKCPPELSADLVERGMVLAGGGALIKG
LDKALSKNTGLSVITAPHPLLAVCLGTGKALEHLDQLKKRKESLV

Specific function: Involved in formation of the rod shape of the cell [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=332, Percent_Identity=57.2289156626506, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1788875, Length=228, Percent_Identity=28.5087719298246, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 39530; Mature: 39399

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPHRSLYKFKNFSNRLYNKALGRFDRVFNFFSGNVGIDLGTANTLVYVRGRGIVLSEPS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCEEEEECCC
VVAVDAQTHAVLAVGHKAKAMLGKTPRKIVAVRPMKDGVIADFEIAEGMLKALIKRVTPA
EEEEECCCCEEEEECCHHHHHHCCCCCCEEEEECCCCCCEECHHHHHHHHHHHHHHCCCH
RSMFRPKILIAVPSGITGVEKRAVEDSALHAGAQEVILIEEPMAAAIGVDLPVHEPAASM
HHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCCCCCCCE
IIDIGGGTTEIAIISLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITI
EEECCCCCEEEEEEEECCEEECCCEEECCCHHHHHHHHHHHHHHEEEECCCCCCEEEEEE
GSAYPLGDQELEMEVRGRDQVAGLPITKRINSVEIRECLAEPIQQIIECVRLTLEKCPPE
ECCCCCCCCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSADLVERGMVLAGGGALIKGLDKALSKNTGLSVITAPHPLLAVCLGTGKALEHLDQLKK
CHHHHHHCCEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCHHHHHHHHHHH
RKESLV
HHHCCC
>Mature Secondary Structure 
SPHRSLYKFKNFSNRLYNKALGRFDRVFNFFSGNVGIDLGTANTLVYVRGRGIVLSEPS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCEEEEECCC
VVAVDAQTHAVLAVGHKAKAMLGKTPRKIVAVRPMKDGVIADFEIAEGMLKALIKRVTPA
EEEEECCCCEEEEECCHHHHHHCCCCCCEEEEECCCCCCEECHHHHHHHHHHHHHHCCCH
RSMFRPKILIAVPSGITGVEKRAVEDSALHAGAQEVILIEEPMAAAIGVDLPVHEPAASM
HHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCCCCCCCE
IIDIGGGTTEIAIISLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITI
EEECCCCCEEEEEEEECCEEECCCEEECCCHHHHHHHHHHHHHHEEEECCCCCCEEEEEE
GSAYPLGDQELEMEVRGRDQVAGLPITKRINSVEIRECLAEPIQQIIECVRLTLEKCPPE
ECCCCCCCCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSADLVERGMVLAGGGALIKGLDKALSKNTGLSVITAPHPLLAVCLGTGKALEHLDQLKK
CHHHHHHCCEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCHHHHHHHHHHH
RKESLV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377; 8387996 [H]