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The map label for this gene is yciC [H]

Identifier: 158338888

GI number: 158338888

Start: 5883101

End: 5884228

Strand: Direct

Name: yciC [H]

Synonym: AM1_5801

Alternate gene names: 158338888

Gene position: 5883101-5884228 (Clockwise)

Preceding gene: 158338887

Following gene: 158338889

Centisome position: 90.46

GC content: 46.28

Gene sequence:

>1128_bases
ATGACCACAACAACTCCCGAATCCACTCAGACCATGACGGCTAACAAGCGTGGGTTACCCGTCACCATTATCACGGGCTT
TTTGGGCAGTGGAAAAACAACCCTTTTAAACCACATTCTCTCCAATCAGGAAGGTTTAAGAACGGCTGTTCTGGTCAATG
AGTTTGGTGAAATTGGCATTGATAATGATCTCCTGATCACCACGGGTGATGACATGGTGGAGCTGAGCAATGGCTGTATC
TGCTGCACTATAAATAATGATTTAGTAGATGCGGTTTATAAGGTTCTGGAGCGGTCTGAAAAGATTGATTATCTGGTGGT
GGAAACTACAGGATTAGCCGATCCTTTACCAGTCGCTTTGACCTTCCTAGGCACCGATTTACGAGATGTGACTCGCTTAG
ATTCAATTGTAACGGTGGTCGATTCTGAGAATTTCAGTTTGGATCTGTTCAATAGTGAAGCCGCTCAAAGCCAGATTGCC
TATGGCGATATTATCTTGCTTAACAAAGCTGATCTAGTGGATGAAGCGAATCTGGATCTGCTAGAAGTGCGGGTCCGGGA
AATGCGTGAAGGTGCTCGGATCATCAGGACCACTAAAAGCCAGGTTTCCCTACCGTTGATTTTGAGTGTCGGGCTATTTG
AATCCGATAAGTATTTTGATGAGCACGGCCACGGCCACAGCCATGACCATAGCCACGATCACGACCATCATGATCACGAT
CATGGCCACGACCATCACGACCACAGCAATTGCGACCATGACCATGGCCATTGCGAGCATGATCACGACCATCATCACTC
CCATCATTTAGATAACGATGGGTTTACATCCCTCTCTTTTCAAAGCGATCGCCCCTTTTCAGTTCGCAAGTTTCAAAAGT
TCTTGGATGAACAGCTTCCCCTCAACGTCTTCCGAGCCAAAGGGATTCTGTGGTTTGATGAAAGCGAGAAGCGTCATGTC
TTTCATTTAAGTGGTAAGCGCTTTTCCTTAGATGATGAGGACTGGAGAGGCGAGCCCAAGAATCAGCTGGTGTTAATTGG
GCAAGATTTGGATCATGATCAGTTGCGATCGCAAATCGAAAACTGCTTAACCACCAATTCCACCAATAGCAGCAAAGGAT
TTGGCTAA

Upstream 100 bases:

>100_bases
AAAAATTAGGACTTCCCCCGAGTGCCATCCTTTAGTATGTAGAGGTGGGGACTACACTCTTTATATTTGTTCTTCAGCGG
CTGCATCTCTGAGCAAGACT

Downstream 100 bases:

>100_bases
GAAATGATTCTGGCGTTTATGGCTTCAACCCATAAACGCTATACTTGCGAGGTAGATTAATTATCTACCCCAATAAGGGC
ATGTAGCTCAGTGGATAGAG

Product: CobW/P47K domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTTTTPESTQTMTANKRGLPVTIITGFLGSGKTTLLNHILSNQEGLRTAVLVNEFGEIGIDNDLLITTGDDMVELSNGCI
CCTINNDLVDAVYKVLERSEKIDYLVVETTGLADPLPVALTFLGTDLRDVTRLDSIVTVVDSENFSLDLFNSEAAQSQIA
YGDIILLNKADLVDEANLDLLEVRVREMREGARIIRTTKSQVSLPLILSVGLFESDKYFDEHGHGHSHDHSHDHDHHDHD
HGHDHHDHSNCDHDHGHCEHDHDHHHSHHLDNDGFTSLSFQSDRPFSVRKFQKFLDEQLPLNVFRAKGILWFDESEKRHV
FHLSGKRFSLDDEDWRGEPKNQLVLIGQDLDHDQLRSQIENCLTTNSTNSSKGFG

Sequences:

>Translated_375_residues
MTTTTPESTQTMTANKRGLPVTIITGFLGSGKTTLLNHILSNQEGLRTAVLVNEFGEIGIDNDLLITTGDDMVELSNGCI
CCTINNDLVDAVYKVLERSEKIDYLVVETTGLADPLPVALTFLGTDLRDVTRLDSIVTVVDSENFSLDLFNSEAAQSQIA
YGDIILLNKADLVDEANLDLLEVRVREMREGARIIRTTKSQVSLPLILSVGLFESDKYFDEHGHGHSHDHSHDHDHHDHD
HGHDHHDHSNCDHDHGHCEHDHDHHHSHHLDNDGFTSLSFQSDRPFSVRKFQKFLDEQLPLNVFRAKGILWFDESEKRHV
FHLSGKRFSLDDEDWRGEPKNQLVLIGQDLDHDQLRSQIENCLTTNSTNSSKGFG
>Mature_374_residues
TTTTPESTQTMTANKRGLPVTIITGFLGSGKTTLLNHILSNQEGLRTAVLVNEFGEIGIDNDLLITTGDDMVELSNGCIC
CTINNDLVDAVYKVLERSEKIDYLVVETTGLADPLPVALTFLGTDLRDVTRLDSIVTVVDSENFSLDLFNSEAAQSQIAY
GDIILLNKADLVDEANLDLLEVRVREMREGARIIRTTKSQVSLPLILSVGLFESDKYFDEHGHGHSHDHSHDHDHHDHDH
GHDHHDHSNCDHDHGHCEHDHDHHHSHHLDNDGFTSLSFQSDRPFSVRKFQKFLDEQLPLNVFRAKGILWFDESEKRHVF
HLSGKRFSLDDEDWRGEPKNQLVLIGQDLDHDQLRSQIENCLTTNSTNSSKGFG

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=230, Percent_Identity=39.5652173913043, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI126722884, Length=230, Percent_Identity=39.5652173913043, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI223941779, Length=221, Percent_Identity=39.3665158371041, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI148727351, Length=230, Percent_Identity=39.1304347826087, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI146231952, Length=230, Percent_Identity=39.1304347826087, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI223941776, Length=216, Percent_Identity=37.037037037037, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI119120938, Length=151, Percent_Identity=42.3841059602649, Blast_Score=112, Evalue=8e-25,
Organism=Escherichia coli, GI87082430, Length=349, Percent_Identity=29.7994269340974, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788499, Length=158, Percent_Identity=37.9746835443038, Blast_Score=89, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324356, Length=244, Percent_Identity=33.6065573770492, Blast_Score=116, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 42230; Mature: 42099

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTTPESTQTMTANKRGLPVTIITGFLGSGKTTLLNHILSNQEGLRTAVLVNEFGEIGI
CCCCCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCEEHHHHHHHHCCCC
DNDLLITTGDDMVELSNGCICCTINNDLVDAVYKVLERSEKIDYLVVETTGLADPLPVAL
CCCEEEECCCCCEECCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
TFLGTDLRDVTRLDSIVTVVDSENFSLDLFNSEAAQSQIAYGDIILLNKADLVDEANLDL
HHHCCCHHHHHHHHHEEEEEECCCCEEEEECCHHHHHHCCCCCEEEEECCCCCCCCCCHH
LEVRVREMREGARIIRTTKSQVSLPLILSVGLFESDKYFDEHGHGHSHDHSHDHDHHDHD
HHHHHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCCCHHHHCCCCCCCCCCCCCCCCCCC
HGHDHHDHSNCDHDHGHCEHDHDHHHSHHLDNDGFTSLSFQSDRPFSVRKFQKFLDEQLP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCC
LNVFRAKGILWFDESEKRHVFHLSGKRFSLDDEDWRGEPKNQLVLIGQDLDHDQLRSQIE
CEEEHHCCEEEECCCCCCEEEEECCCEECCCCHHCCCCCCCCEEEEECCCCHHHHHHHHH
NCLTTNSTNSSKGFG
HHHCCCCCCCCCCCC
>Mature Secondary Structure 
TTTTPESTQTMTANKRGLPVTIITGFLGSGKTTLLNHILSNQEGLRTAVLVNEFGEIGI
CCCCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCEEHHHHHHHHCCCC
DNDLLITTGDDMVELSNGCICCTINNDLVDAVYKVLERSEKIDYLVVETTGLADPLPVAL
CCCEEEECCCCCEECCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
TFLGTDLRDVTRLDSIVTVVDSENFSLDLFNSEAAQSQIAYGDIILLNKADLVDEANLDL
HHHCCCHHHHHHHHHEEEEEECCCCEEEEECCHHHHHHCCCCCEEEEECCCCCCCCCCHH
LEVRVREMREGARIIRTTKSQVSLPLILSVGLFESDKYFDEHGHGHSHDHSHDHDHHDHD
HHHHHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCCCHHHHCCCCCCCCCCCCCCCCCCC
HGHDHHDHSNCDHDHGHCEHDHDHHHSHHLDNDGFTSLSFQSDRPFSVRKFQKFLDEQLP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCC
LNVFRAKGILWFDESEKRHVFHLSGKRFSLDDEDWRGEPKNQLVLIGQDLDHDQLRSQIE
CEEEHHCCEEEECCCCCCEEEEECCCEECCCCHHCCCCCCCCEEEEECCCCHHHHHHHHH
NCLTTNSTNSSKGFG
HHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]