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The map label for this gene is yycF [H]

Identifier: 158338752

GI number: 158338752

Start: 5727341

End: 5728072

Strand: Direct

Name: yycF [H]

Synonym: AM1_5663

Alternate gene names: 158338752

Gene position: 5727341-5728072 (Clockwise)

Preceding gene: 158338746

Following gene: 158338754

Centisome position: 88.06

GC content: 49.18

Gene sequence:

>732_bases
TTGGAAAATCATAAAGAGAAAATTCTGGTGGTCGACGATGAAGCGAGTATTCGTCGCATCCTAGAAACACGCCTCTCCAT
GATTGGCTACGATGTCGTCACCGCCGCAGATGGAGAAGAAGCCATCGACACATTCCATCACGCCATTCCTGACTTAGTTG
TCCTTGATGTCATGATGCCAAAACTAGACGGCTATGGCGTCTGCCAAGAACTCCGCAAAGAATCCGACGTTCCCATTATT
ATGTTGACCGCCTTAGGGGATGTCGCTGATCGCATTACCGGTTTGGAACTCGGTGCAGATGACTATGTGGTTAAACCGTT
TTCACCGAAAGAATTAGAAGCTCGCATTCGCTCCGTGCTAAGGCGTGTGAGCAAAAATGGTAACTCTGGTATTCCCAGCT
CCGGGGTGATCAGTGTCCATACCTTGAAGATTGATACCAATAAGCGCCAGGTCTATAAGGGAGATGAGCGCATTCGGCTC
ACCGGCATGGAGTTTAGCCTGCTGGAATTATTGGTCAGTCGCTCCGGTGAAGCCTTCTCCCGCTCCGATATTTTGCAAGA
AGTTTGGGGTTATACCCCGGAACGCCATGTGGATACTCGGGTGGTGGATGTCCATATTTCTCGATTGAGAGCCAAACTGG
AAGAGGATCCCAGTAATCCTGAACTGATTTTGACCGCTAGAGGGACAGGGTATCTGTTTCAGCGAATTGTTGAGCCTGGG
GAAATGCCTTAA

Upstream 100 bases:

>100_bases
TTCAGCGTTTTTTCCTGTTACTAACTTCATGCTAACTTAATAACAGAGGACTAAAATTTAACTTTTAGAAATGACTCGCA
ATTAAGGAGCATTACGGAAA

Downstream 100 bases:

>100_bases
GGCTTAGCTGTACCACATCCAATTTAGTAAAGCGATGCCCTATAGATTGATATCTATAGGCGTTTTGCTATGGAAACTTA
TCTTTTCAACATCACTGACT

Product: two-component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MENHKEKILVVDDEASIRRILETRLSMIGYDVVTAADGEEAIDTFHHAIPDLVVLDVMMPKLDGYGVCQELRKESDVPII
MLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVSKNGNSGIPSSGVISVHTLKIDTNKRQVYKGDERIRL
TGMEFSLLELLVSRSGEAFSRSDILQEVWGYTPERHVDTRVVDVHISRLRAKLEEDPSNPELILTARGTGYLFQRIVEPG
EMP

Sequences:

>Translated_243_residues
MENHKEKILVVDDEASIRRILETRLSMIGYDVVTAADGEEAIDTFHHAIPDLVVLDVMMPKLDGYGVCQELRKESDVPII
MLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVSKNGNSGIPSSGVISVHTLKIDTNKRQVYKGDERIRL
TGMEFSLLELLVSRSGEAFSRSDILQEVWGYTPERHVDTRVVDVHISRLRAKLEEDPSNPELILTARGTGYLFQRIVEPG
EMP
>Mature_243_residues
MENHKEKILVVDDEASIRRILETRLSMIGYDVVTAADGEEAIDTFHHAIPDLVVLDVMMPKLDGYGVCQELRKESDVPII
MLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVSKNGNSGIPSSGVISVHTLKIDTNKRQVYKGDERIRL
TGMEFSLLELLVSRSGEAFSRSDILQEVWGYTPERHVDTRVVDVHISRLRAKLEEDPSNPELILTARGTGYLFQRIVEPG
EMP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=240, Percent_Identity=43.75, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=40.8695652173913, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=38.3620689655172, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=41.304347826087, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=41.8803418803419, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=34.8017621145374, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1788394, Length=234, Percent_Identity=34.1880341880342, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=37.7682403433476, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=35.7758620689655, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=33.6244541484716, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=34.6320346320346, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=33.1858407079646, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=32.4561403508772, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=31.5126050420168, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=37.0689655172414, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=34.2105263157895, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788191, Length=127, Percent_Identity=31.496062992126, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790299, Length=101, Percent_Identity=32.6732673267327, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI145693157, Length=129, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27238; Mature: 27238

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENHKEKILVVDDEASIRRILETRLSMIGYDVVTAADGEEAIDTFHHAIPDLVVLDVMMP
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHH
KLDGYGVCQELRKESDVPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVL
CCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCHHHHHHHHHHHH
RRVSKNGNSGIPSSGVISVHTLKIDTNKRQVYKGDERIRLTGMEFSLLELLVSRSGEAFS
HHHHCCCCCCCCCCCEEEEEEEEEECCCCCEECCCCEEEEECCHHHHHHHHHHCCCCCHH
RSDILQEVWGYTPERHVDTRVVDVHISRLRAKLEEDPSNPELILTARGTGYLFQRIVEPG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHCCCC
EMP
CCC
>Mature Secondary Structure
MENHKEKILVVDDEASIRRILETRLSMIGYDVVTAADGEEAIDTFHHAIPDLVVLDVMMP
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHH
KLDGYGVCQELRKESDVPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVL
CCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCHHHHHHHHHHHH
RRVSKNGNSGIPSSGVISVHTLKIDTNKRQVYKGDERIRLTGMEFSLLELLVSRSGEAFS
HHHHCCCCCCCCCCCEEEEEEEEEECCCCCEECCCCEEEEECCHHHHHHHHHHCCCCCHH
RSDILQEVWGYTPERHVDTRVVDVHISRLRAKLEEDPSNPELILTARGTGYLFQRIVEPG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHCCCC
EMP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]