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The map label for this gene is rtxC [H]

Identifier: 158338737

GI number: 158338737

Start: 5709926

End: 5710564

Strand: Direct

Name: rtxC [H]

Synonym: AM1_5645

Alternate gene names: 158338737

Gene position: 5709926-5710564 (Clockwise)

Preceding gene: 158338735

Following gene: 158338738

Centisome position: 87.79

GC content: 47.1

Gene sequence:

>639_bases
ATGACCACTACCCCCGCAACAACTGAATTCGATCTAGAGCAAATCCAAGAAGCACCTGAAGCAGACCTCGTGATACCCGT
TGATAACGCAGCTATCCCTGAACCTATTGAAGCGACAGATGGCCATCCAGAACAAGATGCTATTACTTCAGGTTCAACTG
AAGAACAAGCCCCTACTCCTGAACAACGGGAAGAGGCTCAAGCTCAAACCTCACCAGAGGTGATGCGGCAGCGATTACAA
CTTTTAGGCGGCATTACTTGGTTAATGTTGCAATCTCCCCAACACTGGCATTGCACCATCGAAGAATTAGAAGCGAGAAT
TTTACCCAGTCTCACCCTCAACCAATTTCGTTATTACGAAGTCGGTGGTCAGCCTATCGGATTTGTGAGTTGGGCTTACT
TGTCCGATGAGGCAGAAGAGAAGTATCAAACTGGAGAATACAAGCTGCTTCCCCAAGAGTGGCGGAGTGGTGAACGGCTT
TGGTGTACCGATTTTATTTCACCTTTTGAGCATGACCAAAGTATATTTGAGGACTTGCGCCAGACGATTTTTCCCCAGGG
CACAACAGCAAAAATGATCCGCACCCAAGAAGATGGCTCTCGCTCCATCGTTGAATATCAACTGGGATCCAATGAATAA

Upstream 100 bases:

>100_bases
ATCTACCGTTTGATTTGGCGATAGTAGGGACATCAACGAAGCAACGACCACACAGGACAGCTTCTAAATCTTTTAACCCA
ATCAATACAGGTAATCCATC

Downstream 100 bases:

>100_bases
GAGACATCACCCAAGCTGAAGTTGTAATAGATGCGCTTCAGACCACCCAAATTTTAAAAATTGAATGATCACCTCACTCC
TGTGGAATGGTTTGACTTGC

Product: RTX toxin acyltransferase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTTTPATTEFDLEQIQEAPEADLVIPVDNAAIPEPIEATDGHPEQDAITSGSTEEQAPTPEQREEAQAQTSPEVMRQRLQ
LLGGITWLMLQSPQHWHCTIEELEARILPSLTLNQFRYYEVGGQPIGFVSWAYLSDEAEEKYQTGEYKLLPQEWRSGERL
WCTDFISPFEHDQSIFEDLRQTIFPQGTTAKMIRTQEDGSRSIVEYQLGSNE

Sequences:

>Translated_212_residues
MTTTPATTEFDLEQIQEAPEADLVIPVDNAAIPEPIEATDGHPEQDAITSGSTEEQAPTPEQREEAQAQTSPEVMRQRLQ
LLGGITWLMLQSPQHWHCTIEELEARILPSLTLNQFRYYEVGGQPIGFVSWAYLSDEAEEKYQTGEYKLLPQEWRSGERL
WCTDFISPFEHDQSIFEDLRQTIFPQGTTAKMIRTQEDGSRSIVEYQLGSNE
>Mature_211_residues
TTTPATTEFDLEQIQEAPEADLVIPVDNAAIPEPIEATDGHPEQDAITSGSTEEQAPTPEQREEAQAQTSPEVMRQRLQL
LGGITWLMLQSPQHWHCTIEELEARILPSLTLNQFRYYEVGGQPIGFVSWAYLSDEAEEKYQTGEYKLLPQEWRSGERLW
CTDFISPFEHDQSIFEDLRQTIFPQGTTAKMIRTQEDGSRSIVEYQLGSNE

Specific function: Involved in fatty acylation of the protoxin (rtxA) at two internal lysine residues, thereby converting it to the active toxin. The acyl donor is ACP [H]

COG id: COG2994

COG function: function code O; ACP:hemolysin acyltransferase (hemolysin-activating protein)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RTX toxin acyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003996 [H]

Pfam domain/function: PF02794 HlyC [H]

EC number: NA

Molecular weight: Translated: 24148; Mature: 24017

Theoretical pI: Translated: 3.97; Mature: 3.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTPATTEFDLEQIQEAPEADLVIPVDNAAIPEPIEATDGHPEQDAITSGSTEEQAPTP
CCCCCCCCCCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EQREEAQAQTSPEVMRQRLQLLGGITWLMLQSPQHWHCTIEELEARILPSLTLNQFRYYE
HHHHHHHHCCCHHHHHHHHHHHCCHHEEEECCCCCCEEEHHHHHHHHCCCCHHCCEEEEE
VGGQPIGFVSWAYLSDEAEEKYQTGEYKLLPQEWRSGERLWCTDFISPFEHDQSIFEDLR
CCCCCCCCEEEEHHCCHHHHHHCCCCEEECHHHHCCCCEEEEHHHCCCCCCHHHHHHHHH
QTIFPQGTTAKMIRTQEDGSRSIVEYQLGSNE
HHHCCCCCHHHHEEECCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TTTPATTEFDLEQIQEAPEADLVIPVDNAAIPEPIEATDGHPEQDAITSGSTEEQAPTP
CCCCCCCCCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EQREEAQAQTSPEVMRQRLQLLGGITWLMLQSPQHWHCTIEELEARILPSLTLNQFRYYE
HHHHHHHHCCCHHHHHHHHHHHCCHHEEEECCCCCCEEEHHHHHHHHCCCCHHCCEEEEE
VGGQPIGFVSWAYLSDEAEEKYQTGEYKLLPQEWRSGERLWCTDFISPFEHDQSIFEDLR
CCCCCCCCEEEEHHCCHHHHHHCCCCEEECHHHHCCCCEEEEHHHCCCCCCHHHHHHHHH
QTIFPQGTTAKMIRTQEDGSRSIVEYQLGSNE
HHHCCCCCHHHHEEECCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9927695; 10952301 [H]