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The map label for this gene is accA

Identifier: 158338725

GI number: 158338725

Start: 5693842

End: 5694819

Strand: Direct

Name: accA

Synonym: AM1_5633

Alternate gene names: 158338725

Gene position: 5693842-5694819 (Clockwise)

Preceding gene: 158338724

Following gene: 158338726

Centisome position: 87.55

GC content: 49.8

Gene sequence:

>978_bases
ATGGCTGTTTCCGATCGCAAACTCCAACTGCTTGACTTTGAAAAACCCTTAGCTGAATTAGAGGATCGGATTGAGCAGAT
CCGTAGCCTCTCTGAGCAGAATGGGGTGGATGTTACGGATCAAATTGCCCAGCTAGAAGGTCGGGCTGAACAGCTTCGTC
AAGAAATCTTTAGCAGTTTAACTCCGATGCAAGAGCTTCAGCTGGCTCGGCATCCTCGGCGTCCGAGTACCTTGGACTAT
ATCCATGCCATTAGTGATGAATGGATGGAATTGCATGGTGATCGTCGGGGGTATGATGATCCAGCGATTGTTGGGGGTGT
GGGTCGGATTGGTGGCCAGCCCGTGTTGATGTTAGGCCATCAAAAAGGACGCGATACCAAGGATAATGTGGCCCGCAACT
TTGGTATGCCTTTTCCGAGTGGGTATCGGAAAGCAATGCGATTAATGGATCATGCGGATCGGTTTGGCTTGCCTATCATT
TCTTTTATTGATACGCCTGCAGCCTGGGCCGGATTAGAAGCTGAACAATTTGGGCAGGGCGAAGCGATTGCCCTCAACCT
CCGGGAAATGTTCCGACTCGATGTACCCATTATCTGTACAGTGATTGGAGAAGGTGGATCTGGGGGGGCCTTGGGAATCG
GTGTGGGTGATCGGCTATTGATGTTTGAACATTCGATCTATAGCGTTGCGCCACCGGAAGCCTGTGCGGCGATCCTTTGG
CGGGATGCCCAAGAAGGCCCTCAAGCTGCGGAAGCCCTCAAAATTACGGCGACGGATTTGCAAGAACTGGGGATAATCGA
CCAAATTTTGCCTGAGCCCCCTGGAGGAGCGCATGTTAATCCTATTAAGGCTGCAAATATTATTAAAACTGCGATTTTAA
GTAATTTAGAAGAATTATGGCGTCTTAGCCCCCAAGAGCGTCGCCAACAGCGCTATCATAAGTTTCGGAATATGGGGATT
TTTTCCCAGCTTCCTTGA

Upstream 100 bases:

>100_bases
GTTGCCCAGGGCACCCTTGCTAGGATCGATTAATTGTCTTTGGCACTATTAATCAGGACAACAAGGCTGAATTGTTTATC
TTTTGACTAGGTATCTGCGA

Downstream 100 bases:

>100_bases
GTATGCGCTCCATCTTGAACCAGTGGTATGATTACAGGGGCGCAACATTTGTTTACAATTAGCGTAAGCTCACGCGCTTT
GACTGCCTCTCATCTGCGCT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAVSDRKLQLLDFEKPLAELEDRIEQIRSLSEQNGVDVTDQIAQLEGRAEQLRQEIFSSLTPMQELQLARHPRRPSTLDY
IHAISDEWMELHGDRRGYDDPAIVGGVGRIGGQPVLMLGHQKGRDTKDNVARNFGMPFPSGYRKAMRLMDHADRFGLPII
SFIDTPAAWAGLEAEQFGQGEAIALNLREMFRLDVPIICTVIGEGGSGGALGIGVGDRLLMFEHSIYSVAPPEACAAILW
RDAQEGPQAAEALKITATDLQELGIIDQILPEPPGGAHVNPIKAANIIKTAILSNLEELWRLSPQERRQQRYHKFRNMGI
FSQLP

Sequences:

>Translated_325_residues
MAVSDRKLQLLDFEKPLAELEDRIEQIRSLSEQNGVDVTDQIAQLEGRAEQLRQEIFSSLTPMQELQLARHPRRPSTLDY
IHAISDEWMELHGDRRGYDDPAIVGGVGRIGGQPVLMLGHQKGRDTKDNVARNFGMPFPSGYRKAMRLMDHADRFGLPII
SFIDTPAAWAGLEAEQFGQGEAIALNLREMFRLDVPIICTVIGEGGSGGALGIGVGDRLLMFEHSIYSVAPPEACAAILW
RDAQEGPQAAEALKITATDLQELGIIDQILPEPPGGAHVNPIKAANIIKTAILSNLEELWRLSPQERRQQRYHKFRNMGI
FSQLP
>Mature_324_residues
AVSDRKLQLLDFEKPLAELEDRIEQIRSLSEQNGVDVTDQIAQLEGRAEQLRQEIFSSLTPMQELQLARHPRRPSTLDYI
HAISDEWMELHGDRRGYDDPAIVGGVGRIGGQPVLMLGHQKGRDTKDNVARNFGMPFPSGYRKAMRLMDHADRFGLPIIS
FIDTPAAWAGLEAEQFGQGEAIALNLREMFRLDVPIICTVIGEGGSGGALGIGVGDRLLMFEHSIYSVAPPEACAAILWR
DAQEGPQAAEALKITATDLQELGIIDQILPEPPGGAHVNPIKAANIIKTAILSNLEELWRLSPQERRQQRYHKFRNMGIF
SQLP

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:
GO:0000166: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
GO:0003989: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
GO:0005524: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
GO:0005737: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
GO:0006633: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
GO:0008610: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
GO:0009317: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
GO:0016874: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=315, Percent_Identity=52.3809523809524, Blast_Score=340, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_ACAM1 (B0CF67)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001519902.1
- ProteinModelPortal:   B0CF67
- SMR:   B0CF67
- GeneID:   5684423
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_5633
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   AMAR329726:AM1_5633-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 36100; Mature: 35969

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSDRKLQLLDFEKPLAELEDRIEQIRSLSEQNGVDVTDQIAQLEGRAEQLRQEIFSSL
CCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHC
TPMQELQLARHPRRPSTLDYIHAISDEWMELHGDRRGYDDPAIVGGVGRIGGQPVLMLGH
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHCCCCCEEEECC
QKGRDTKDNVARNFGMPFPSGYRKAMRLMDHADRFGLPIISFIDTPAAWAGLEAEQFGQG
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHCCCCHHHCCCC
EAIALNLREMFRLDVPIICTVIGEGGSGGALGIGVGDRLLMFEHSIYSVAPPEACAAILW
CEEEEEHHHHHHCCCCEEEEEEECCCCCCEEEECCCCEEEEEEHHHHCCCCHHHHHHHHH
RDAQEGPQAAEALKITATDLQELGIIDQILPEPPGGAHVNPIKAANIIKTAILSNLEELW
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RLSPQERRQQRYHKFRNMGIFSQLP
CCCHHHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure 
AVSDRKLQLLDFEKPLAELEDRIEQIRSLSEQNGVDVTDQIAQLEGRAEQLRQEIFSSL
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHC
TPMQELQLARHPRRPSTLDYIHAISDEWMELHGDRRGYDDPAIVGGVGRIGGQPVLMLGH
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHCCCCCEEEECC
QKGRDTKDNVARNFGMPFPSGYRKAMRLMDHADRFGLPIISFIDTPAAWAGLEAEQFGQG
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHCCCCHHHCCCC
EAIALNLREMFRLDVPIICTVIGEGGSGGALGIGVGDRLLMFEHSIYSVAPPEACAAILW
CEEEEEHHHHHHCCCCEEEEEEECCCCCCEEEECCCCEEEEEEHHHHCCCCHHHHHHHHH
RDAQEGPQAAEALKITATDLQELGIIDQILPEPPGGAHVNPIKAANIIKTAILSNLEELW
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RLSPQERRQQRYHKFRNMGIFSQLP
CCCHHHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA