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The map label for this gene is dinB [H]

Identifier: 158338583

GI number: 158338583

Start: 5542539

End: 5543606

Strand: Direct

Name: dinB [H]

Synonym: AM1_5486

Alternate gene names: 158338583

Gene position: 5542539-5543606 (Clockwise)

Preceding gene: 158338582

Following gene: 158338584

Centisome position: 85.22

GC content: 50.84

Gene sequence:

>1068_bases
ATGCGTAAGATCCTGCATATCGATATGGATGCGTTCTTCGCCTCCGTGGAGCAGCGAGATAATCCCCGCCTACGAGGCAA
GCCCGTCGTGGTGGGTGGACGTCCAGAACAGCGAGGTGCTGTCGCTGCCGCCAGTTATGAAGCCCGCAAATATGGAATTT
TCTCTGCCACACCATCGCGGGTAGCGGCCACAAAATGCAAGGACCTGATCTTTGTGGCGCCTCGGTTTGAGGTCTACCGC
CAAGTCTCTCAGCAGATTCGAGCTATCTTTCACCAATTTACGGATCTGGTGGAACCAGTCTCTCTAGATGAAGCCTATTT
GGATGTGACGGAGAATAAACCTGAAATAAACTCAGCCATGGCGATTGCCCGAGAAATAAAGGGTTTGATTCATCAGGAAA
CTCACTTAACGGCTTCAGCAGGGGTATCGATCAATAAATTCTTGGCCAAGATGGCGTCTGGATTGGATAAACCCAACGGC
CTGTCTCTGGTCGCTCCCGACCAAGCCGAAGCCTTTGTTCAGCAGCTCCCGATTGAGAAGTTTCACGGCATCGGTAAGGT
CACCGCTGCTAAAATGCACCAGCTCGGCATTCAAACGGGTGCAGAGTTGCGTCAATGGTCCGAACCTTCATTAGTGCGCC
AGTTTGGCAAGGTAGGCCACTACTACTACGGCATCGCTAGGGGTATCGATGAGCGCCCAGTGATTGCCAATCGCATTCGT
AAGTCCATTGGCGCGGAGCGCAGCTTTTTTCCGGATATTTCGGGATTGCCTGTTTTGATGGAAGAACTGGATGCGATCGC
AGCCCAAGTACACCTGCGATTGGCTGAAAATCAACGGTCTGGCCATACCCTGACCCTGAAAGTAAAGTATGCCAACTATC
AACAAATCACCCGCAGTCGGACGGTAGATCATCCCTTATATGAAGTGGATGAAATTTTGGTCCTTGGGAAAGAGTTACTC
CAAAGCCATATCGATGAACAGCAGGCCGTCAGACTATTGGGGCTAACCCTCGCCAATCTTGTAGACAAAGACCGTAGTCC
CAAACAGTTATCGATTGGGTTTGTCTAA

Upstream 100 bases:

>100_bases
CAAGATTTATCGGCTTTGCCGGTGACCACTTTAGTCAACAGTCCGACAGTGGATCGGCCTGAATGTATTGAGCCGATGCT
GTAGCCTCTAGCCAAAAACG

Downstream 100 bases:

>100_bases
GACCGTTTGGGCAACCCCACAAAAAGCAAAGGATGGTGATTCAAAGTGTCTAATCAACCCAAATTTGAAGCAACGTTCCC
CTTTCAAGAGGATGTGCTAG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 2 [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MRKILHIDMDAFFASVEQRDNPRLRGKPVVVGGRPEQRGAVAAASYEARKYGIFSATPSRVAATKCKDLIFVAPRFEVYR
QVSQQIRAIFHQFTDLVEPVSLDEAYLDVTENKPEINSAMAIAREIKGLIHQETHLTASAGVSINKFLAKMASGLDKPNG
LSLVAPDQAEAFVQQLPIEKFHGIGKVTAAKMHQLGIQTGAELRQWSEPSLVRQFGKVGHYYYGIARGIDERPVIANRIR
KSIGAERSFFPDISGLPVLMEELDAIAAQVHLRLAENQRSGHTLTLKVKYANYQQITRSRTVDHPLYEVDEILVLGKELL
QSHIDEQQAVRLLGLTLANLVDKDRSPKQLSIGFV

Sequences:

>Translated_355_residues
MRKILHIDMDAFFASVEQRDNPRLRGKPVVVGGRPEQRGAVAAASYEARKYGIFSATPSRVAATKCKDLIFVAPRFEVYR
QVSQQIRAIFHQFTDLVEPVSLDEAYLDVTENKPEINSAMAIAREIKGLIHQETHLTASAGVSINKFLAKMASGLDKPNG
LSLVAPDQAEAFVQQLPIEKFHGIGKVTAAKMHQLGIQTGAELRQWSEPSLVRQFGKVGHYYYGIARGIDERPVIANRIR
KSIGAERSFFPDISGLPVLMEELDAIAAQVHLRLAENQRSGHTLTLKVKYANYQQITRSRTVDHPLYEVDEILVLGKELL
QSHIDEQQAVRLLGLTLANLVDKDRSPKQLSIGFV
>Mature_355_residues
MRKILHIDMDAFFASVEQRDNPRLRGKPVVVGGRPEQRGAVAAASYEARKYGIFSATPSRVAATKCKDLIFVAPRFEVYR
QVSQQIRAIFHQFTDLVEPVSLDEAYLDVTENKPEINSAMAIAREIKGLIHQETHLTASAGVSINKFLAKMASGLDKPNG
LSLVAPDQAEAFVQQLPIEKFHGIGKVTAAKMHQLGIQTGAELRQWSEPSLVRQFGKVGHYYYGIARGIDERPVIANRIR
KSIGAERSFFPDISGLPVLMEELDAIAAQVHLRLAENQRSGHTLTLKVKYANYQQITRSRTVDHPLYEVDEILVLGKELL
QSHIDEQQAVRLLGLTLANLVDKDRSPKQLSIGFV

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:
GO:0000287: DNA polymerase IV
GO:0003677: DNA polymerase IV
GO:0003684: DNA polymerase IV
GO:0003887: DNA polymerase IV
GO:0005737: DNA polymerase IV
GO:0006260: DNA polymerase IV
GO:0006261: DNA polymerase IV
GO:0006281: DNA polymerase IV
GO:0006974: DNA polymerase IV
GO:0016740: DNA polymerase IV
GO:0016779: DNA polymerase IV
GO:0046872: DNA polymerase IV

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7705344, Length=444, Percent_Identity=29.2792792792793, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI84043967, Length=386, Percent_Identity=27.2020725388601, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI7706681, Length=387, Percent_Identity=27.1317829457364, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI154350220, Length=325, Percent_Identity=28.6153846153846, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI5729982, Length=319, Percent_Identity=29.153605015674, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1786425, Length=304, Percent_Identity=42.7631578947368, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1787432, Length=295, Percent_Identity=27.4576271186441, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193205700, Length=405, Percent_Identity=29.8765432098765, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17537959, Length=302, Percent_Identity=29.1390728476821, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=349, Percent_Identity=28.080229226361, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI115534089, Length=367, Percent_Identity=24.2506811989101, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19923006, Length=416, Percent_Identity=26.2019230769231, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21355641, Length=288, Percent_Identity=27.0833333333333, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24644984, Length=288, Percent_Identity=27.0833333333333, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24668444, Length=239, Percent_Identity=26.7782426778243, Blast_Score=95, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39556; Mature: 39556

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKILHIDMDAFFASVEQRDNPRLRGKPVVVGGRPEQRGAVAAASYEARKYGIFSATPSR
CCCEEEECHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCEEHCCHHHHHCCCCCCCCHH
VAATKCKDLIFVAPRFEVYRQVSQQIRAIFHQFTDLVEPVSLDEAYLDVTENKPEINSAM
HHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHH
AIAREIKGLIHQETHLTASAGVSINKFLAKMASGLDKPNGLSLVAPDQAEAFVQQLPIEK
HHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHCCHHH
FHGIGKVTAAKMHQLGIQTGAELRQWSEPSLVRQFGKVGHYYYGIARGIDERPVIANRIR
HCCCCHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
KSIGAERSFFPDISGLPVLMEELDAIAAQVHLRLAENQRSGHTLTLKVKYANYQQITRSR
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHH
TVDHPLYEVDEILVLGKELLQSHIDEQQAVRLLGLTLANLVDKDRSPKQLSIGFV
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCC
>Mature Secondary Structure
MRKILHIDMDAFFASVEQRDNPRLRGKPVVVGGRPEQRGAVAAASYEARKYGIFSATPSR
CCCEEEECHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCEEHCCHHHHHCCCCCCCCHH
VAATKCKDLIFVAPRFEVYRQVSQQIRAIFHQFTDLVEPVSLDEAYLDVTENKPEINSAM
HHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHH
AIAREIKGLIHQETHLTASAGVSINKFLAKMASGLDKPNGLSLVAPDQAEAFVQQLPIEK
HHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHCCHHH
FHGIGKVTAAKMHQLGIQTGAELRQWSEPSLVRQFGKVGHYYYGIARGIDERPVIANRIR
HCCCCHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
KSIGAERSFFPDISGLPVLMEELDAIAAQVHLRLAENQRSGHTLTLKVKYANYQQITRSR
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHH
TVDHPLYEVDEILVLGKELLQSHIDEQQAVRLLGLTLANLVDKDRSPKQLSIGFV
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]