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The map label for this gene is 158338526

Identifier: 158338526

GI number: 158338526

Start: 5485714

End: 5486640

Strand: Reverse

Name: 158338526

Synonym: AM1_5428

Alternate gene names: NA

Gene position: 5486640-5485714 (Counterclockwise)

Preceding gene: 158338527

Following gene: 158338525

Centisome position: 84.36

GC content: 49.51

Gene sequence:

>927_bases
ATGAGCCACATGCTACCCATTGTTTATTCGGATCGCTTTCTTGAACATTTAACAGGTCCCTACCATCCCGAAAAACCGGA
ACGGTTAACGGCAATTAAAACCGCACTAGAACAAGCTTCCTGGGCCGATCAATTACAGTGGTTATTGCCCACTCCCATCA
CGCAACGTGATCCTTTGGAATGGATTAACCGCGTTCATACTGCTGACTATATCCAGCAAGTTCAATCTTTGGCTAAATCG
GGGGGCGGCTATCTCGATCCGGATACGGTGGTGTCTCCTCAAAGTTATGAAGTGGCTTTACTGGCTGTGAATGCTTGGAT
GGATGGTGTTGATCTGGTGCTATCCCGACAATCCCCCGCCTTTGTGTTGGCCAGACCCCCGGGGCACCATGCGGTACAAG
AGACAGGCATGGGGTTTTGCCTGTTTTCCAATGCTGCGATCGCAGCCTACTACGCCCTCACCCAACCTGGTATTGAGCGA
GTCGCCATTCTCGATTGGGATGTTCACCATGGCAATGGCACCCAAGCGATTGTGGAGTCCCATGCTCAGATTGCCTACTG
CTCTCTGCATCAATCCCCTTGCTACCCCGGTACAGGAACGGCGGGTGAAACAGGTTTGCATGGCAATGTCCTGAATTTGC
CGATGCGGGCAGGCAGCACGTTGGCAGATTATGAGCCGCAATTTAAAGATAAGATCATGCCCTTCTTTCAGGACTTCAAT
CCTGATTTACTGTTGGTCAGTGCCGGATACGATGCCAATGCTGCTGATCCGTTAGCGGGTATCCATTTAGCGCCCCAAGA
TTATGGTGTTTTCACTCAGTACTGCCGCCAACTGACCTCCAAAATACTATTTGGTTTAGAGGGTGGATATGATTTATCTG
CTTTAGCTCAGTCTGTATTTTTCACCCTTGAAGTCTGTTTGAAATGA

Upstream 100 bases:

>100_bases
ATCTGAAAAAATCTTAATCTCTAAAGTGCAGGAGTTGAATGAGGTCTTGAGTGCCAGTATTCTTAAACCACTAAACTCGG
TCCCACTTTATAACCAAAGG

Downstream 100 bases:

>100_bases
CTGTATTGCTTTTATTCTTAATGAATCAAAATAGGGTAGATGGGCTTAGATTGAATCTGGTTTCTTGTAGCGCGCAATAG
CAGGGCTGTTGATCTGAACT

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSHMLPIVYSDRFLEHLTGPYHPEKPERLTAIKTALEQASWADQLQWLLPTPITQRDPLEWINRVHTADYIQQVQSLAKS
GGGYLDPDTVVSPQSYEVALLAVNAWMDGVDLVLSRQSPAFVLARPPGHHAVQETGMGFCLFSNAAIAAYYALTQPGIER
VAILDWDVHHGNGTQAIVESHAQIAYCSLHQSPCYPGTGTAGETGLHGNVLNLPMRAGSTLADYEPQFKDKIMPFFQDFN
PDLLLVSAGYDANAADPLAGIHLAPQDYGVFTQYCRQLTSKILFGLEGGYDLSALAQSVFFTLEVCLK

Sequences:

>Translated_308_residues
MSHMLPIVYSDRFLEHLTGPYHPEKPERLTAIKTALEQASWADQLQWLLPTPITQRDPLEWINRVHTADYIQQVQSLAKS
GGGYLDPDTVVSPQSYEVALLAVNAWMDGVDLVLSRQSPAFVLARPPGHHAVQETGMGFCLFSNAAIAAYYALTQPGIER
VAILDWDVHHGNGTQAIVESHAQIAYCSLHQSPCYPGTGTAGETGLHGNVLNLPMRAGSTLADYEPQFKDKIMPFFQDFN
PDLLLVSAGYDANAADPLAGIHLAPQDYGVFTQYCRQLTSKILFGLEGGYDLSALAQSVFFTLEVCLK
>Mature_307_residues
SHMLPIVYSDRFLEHLTGPYHPEKPERLTAIKTALEQASWADQLQWLLPTPITQRDPLEWINRVHTADYIQQVQSLAKSG
GGYLDPDTVVSPQSYEVALLAVNAWMDGVDLVLSRQSPAFVLARPPGHHAVQETGMGFCLFSNAAIAAYYALTQPGIERV
AILDWDVHHGNGTQAIVESHAQIAYCSLHQSPCYPGTGTAGETGLHGNVLNLPMRAGSTLADYEPQFKDKIMPFFQDFNP
DLLLVSAGYDANAADPLAGIHLAPQDYGVFTQYCRQLTSKILFGLEGGYDLSALAQSVFFTLEVCLK

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=315, Percent_Identity=34.6031746031746, Blast_Score=161, Evalue=6e-40,
Organism=Homo sapiens, GI20070354, Length=301, Percent_Identity=32.5581395348837, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI169234807, Length=331, Percent_Identity=30.2114803625378, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI148539870, Length=331, Percent_Identity=30.2114803625378, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI17158039, Length=286, Percent_Identity=32.8671328671329, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI30795204, Length=286, Percent_Identity=32.8671328671329, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI30795202, Length=286, Percent_Identity=32.8671328671329, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI153085395, Length=330, Percent_Identity=31.2121212121212, Blast_Score=128, Evalue=6e-30,
Organism=Homo sapiens, GI62750349, Length=239, Percent_Identity=33.0543933054393, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI62750347, Length=239, Percent_Identity=33.0543933054393, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI226529806, Length=301, Percent_Identity=28.9036544850498, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI8923769, Length=305, Percent_Identity=24.2622950819672, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI13128862, Length=294, Percent_Identity=24.4897959183673, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI262073088, Length=176, Percent_Identity=28.4090909090909, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI13128860, Length=303, Percent_Identity=21.7821782178218, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI293336691, Length=260, Percent_Identity=23.4615384615385, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=311, Percent_Identity=34.0836012861736, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI193206283, Length=311, Percent_Identity=34.0836012861736, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17540332, Length=311, Percent_Identity=34.0836012861736, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17537347, Length=303, Percent_Identity=34.983498349835, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI193209491, Length=308, Percent_Identity=32.4675324675325, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25154020, Length=299, Percent_Identity=26.7558528428094, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI25154022, Length=299, Percent_Identity=26.4214046822742, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17508561, Length=314, Percent_Identity=24.5222929936306, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17534739, Length=295, Percent_Identity=23.0508474576271, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561978, Length=222, Percent_Identity=25.2252252252252, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324307, Length=313, Percent_Identity=32.2683706070287, Blast_Score=143, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6325141, Length=289, Percent_Identity=25.6055363321799, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323999, Length=298, Percent_Identity=22.1476510067114, Blast_Score=75, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6321244, Length=288, Percent_Identity=23.9583333333333, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6325325, Length=131, Percent_Identity=27.4809160305344, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281360899, Length=302, Percent_Identity=35.4304635761589, Blast_Score=167, Evalue=8e-42,
Organism=Drosophila melanogaster, GI24642146, Length=306, Percent_Identity=35.2941176470588, Blast_Score=167, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24642144, Length=306, Percent_Identity=35.2941176470588, Blast_Score=167, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24642142, Length=306, Percent_Identity=35.2941176470588, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281360799, Length=197, Percent_Identity=41.1167512690355, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24641720, Length=317, Percent_Identity=33.4384858044164, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281360801, Length=317, Percent_Identity=33.4384858044164, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24644244, Length=298, Percent_Identity=24.496644295302, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24657891, Length=303, Percent_Identity=21.4521452145215, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33818; Mature: 33686

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHMLPIVYSDRFLEHLTGPYHPEKPERLTAIKTALEQASWADQLQWLLPTPITQRDPLE
CCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
WINRVHTADYIQQVQSLAKSGGGYLDPDTVVSPQSYEVALLAVNAWMDGVDLVLSRQSPA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCEEEEEEEECHHCCHHEEEECCCCE
FVLARPPGHHAVQETGMGFCLFSNAAIAAYYALTQPGIERVAILDWDVHHGNGTQAIVES
EEEECCCCCHHHHHCCCEEEEECCCHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHHC
HAQIAYCSLHQSPCYPGTGTAGETGLHGNVLNLPMRAGSTLADYEPQFKDKIMPFFQDFN
CCCEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCC
PDLLLVSAGYDANAADPLAGIHLAPQDYGVFTQYCRQLTSKILFGLEGGYDLSALAQSVF
CCEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
FTLEVCLK
HHHHHHCC
>Mature Secondary Structure 
SHMLPIVYSDRFLEHLTGPYHPEKPERLTAIKTALEQASWADQLQWLLPTPITQRDPLE
CCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
WINRVHTADYIQQVQSLAKSGGGYLDPDTVVSPQSYEVALLAVNAWMDGVDLVLSRQSPA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCEEEEEEEECHHCCHHEEEECCCCE
FVLARPPGHHAVQETGMGFCLFSNAAIAAYYALTQPGIERVAILDWDVHHGNGTQAIVES
EEEECCCCCHHHHHCCCEEEEECCCHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHHC
HAQIAYCSLHQSPCYPGTGTAGETGLHGNVLNLPMRAGSTLADYEPQFKDKIMPFFQDFN
CCCEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCC
PDLLLVSAGYDANAADPLAGIHLAPQDYGVFTQYCRQLTSKILFGLEGGYDLSALAQSVF
CCEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
FTLEVCLK
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]