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The map label for this gene is ccmA [H]

Identifier: 158338520

GI number: 158338520

Start: 5478530

End: 5479591

Strand: Direct

Name: ccmA [H]

Synonym: AM1_5422

Alternate gene names: 158338520

Gene position: 5478530-5479591 (Clockwise)

Preceding gene: 158338519

Following gene: 158338521

Centisome position: 84.24

GC content: 53.2

Gene sequence:

>1062_bases
ATGATCATCGTCTTCAAAAGCGGTGCACCTGACGCAGAAATTCAGTCCCTCGATCAAGAAATGCGGGATTGGGGGCTGAC
GCCAGAGAAAATTGTGGGGCAACATAAGGTTGTGATTGGCCTTGTCGGTGAGACGGCTGAACTTGATCCCGATCAGATTA
AGGATCTAAACCCTTGGATTGAATCCGTCCTGCGGGTCGAGAAACCCTATAAGCGGGTTAGCCGAGAATATCGCCATGGT
GAAGCTAGTCGCGTAGAGGTACCGACGCCTAAAGGGTCTGTGTTCTTTGGTGAGCCAGATCCGATTGTGCTGGTTGCTGG
TCCCTGCTCTGTTGAGAACGAAGAAATGATTGTGGAGACGGCCCAGCGGGTTGCTGCGGCAGGGGCGTCTTTTTTGCGAG
GGGGTGCCTATAAACCTCGAACCTCCCCCTATGCCTTTCAAGGTCATGGTGAGAGTGCGCTCGGTTTACTAGCTGCAGCC
CGCGAGGCATCTGGATTGGGGATCATTACTGAAGTCATGGACACAGCCGATGTGGAGAAAGTGGCCGAGGTTGCTGATGT
GCTCCAAATTGGGGCTCGCAATATGCAGAACTTCCCTCTCCTTAAAGCTGCTGGTGCCCAACCCAAGCCCGTATTACTAA
AGCGAGGGTTATCCGCCACCATTGATGAATGGTTGATGGCTGCAGAATATATCTTGGCAGCCGGGAATTCCAATGTGATT
CTATGTGAGCGAGGTATCCGCACGTTTGATCGACAGCATCTACGGAATACATTGGATCTCGCAGCAGTCGCCGTATTGCG
AACCCTAACCCATCTCCCCATTATGGTTGATCCCAGTCATGGCACGGGTTGGGCAAGGTTTGTCCCGGCCTTGGCTAAAG
CTGCGATCGCAGTTGGTACTGACTCCCTGATGATTGAAGTCCATCCCAACCCCGCTAAAGCGCTCTCAGACGGTCCTCAA
TCTTTGACCCCCGATCAATTTGATGCATTGACTCAAGAGTTAGGGGTGATTGGGCAGGCGGTCGGTCGCTGGCCTCAAGC
CCTTGCTGCAGCAACGGCCTAA

Upstream 100 bases:

>100_bases
GCTAAGGCAGAGAAGGCATCGGCTAAAGCAGAATCGACTTCACCTAAAACTACAGCCGAAACCTCTGAAGAGGAGTCAGC
TAGCTCGTAAGGAGTCCTCC

Downstream 100 bases:

>100_bases
GACTATTTTTAGGGTAAAAAAATGGAATCTCCTGAAACCATCTGCGAATTTTGGTTTGGGACTGACCAGGATGACTTAGA
CGTCATCCGGCAACGCTCAA

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MIIVFKSGAPDAEIQSLDQEMRDWGLTPEKIVGQHKVVIGLVGETAELDPDQIKDLNPWIESVLRVEKPYKRVSREYRHG
EASRVEVPTPKGSVFFGEPDPIVLVAGPCSVENEEMIVETAQRVAAAGASFLRGGAYKPRTSPYAFQGHGESALGLLAAA
REASGLGIITEVMDTADVEKVAEVADVLQIGARNMQNFPLLKAAGAQPKPVLLKRGLSATIDEWLMAAEYILAAGNSNVI
LCERGIRTFDRQHLRNTLDLAAVAVLRTLTHLPIMVDPSHGTGWARFVPALAKAAIAVGTDSLMIEVHPNPAKALSDGPQ
SLTPDQFDALTQELGVIGQAVGRWPQALAAATA

Sequences:

>Translated_353_residues
MIIVFKSGAPDAEIQSLDQEMRDWGLTPEKIVGQHKVVIGLVGETAELDPDQIKDLNPWIESVLRVEKPYKRVSREYRHG
EASRVEVPTPKGSVFFGEPDPIVLVAGPCSVENEEMIVETAQRVAAAGASFLRGGAYKPRTSPYAFQGHGESALGLLAAA
REASGLGIITEVMDTADVEKVAEVADVLQIGARNMQNFPLLKAAGAQPKPVLLKRGLSATIDEWLMAAEYILAAGNSNVI
LCERGIRTFDRQHLRNTLDLAAVAVLRTLTHLPIMVDPSHGTGWARFVPALAKAAIAVGTDSLMIEVHPNPAKALSDGPQ
SLTPDQFDALTQELGVIGQAVGRWPQALAAATA
>Mature_353_residues
MIIVFKSGAPDAEIQSLDQEMRDWGLTPEKIVGQHKVVIGLVGETAELDPDQIKDLNPWIESVLRVEKPYKRVSREYRHG
EASRVEVPTPKGSVFFGEPDPIVLVAGPCSVENEEMIVETAQRVAAAGASFLRGGAYKPRTSPYAFQGHGESALGLLAAA
REASGLGIITEVMDTADVEKVAEVADVLQIGARNMQNFPLLKAAGAQPKPVLLKRGLSATIDEWLMAAEYILAAGNSNVI
LCERGIRTFDRQHLRNTLDLAAVAVLRTLTHLPIMVDPSHGTGWARFVPALAKAAIAVGTDSLMIEVHPNPAKALSDGPQ
SLTPDQFDALTQELGVIGQAVGRWPQALAAATA

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=260, Percent_Identity=23.8461538461538, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 37814; Mature: 37814

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVFKSGAPDAEIQSLDQEMRDWGLTPEKIVGQHKVVIGLVGETAELDPDQIKDLNPWI
CEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEEEEEECCCCCCCHHHHHCCCHHH
ESVLRVEKPYKRVSREYRHGEASRVEVPTPKGSVFFGEPDPIVLVAGPCSVENEEMIVET
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEECCCCCEEEEECCCCCCCHHHHHHH
AQRVAAAGASFLRGGAYKPRTSPYAFQGHGESALGLLAAAREASGLGIITEVMDTADVEK
HHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VAEVADVLQIGARNMQNFPLLKAAGAQPKPVLLKRGLSATIDEWLMAAEYILAAGNSNVI
HHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEE
LCERGIRTFDRQHLRNTLDLAAVAVLRTLTHLPIMVDPSHGTGWARFVPALAKAAIAVGT
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHCCC
DSLMIEVHPNPAKALSDGPQSLTPDQFDALTQELGVIGQAVGRWPQALAAATA
CEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIVFKSGAPDAEIQSLDQEMRDWGLTPEKIVGQHKVVIGLVGETAELDPDQIKDLNPWI
CEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEEEEEECCCCCCCHHHHHCCCHHH
ESVLRVEKPYKRVSREYRHGEASRVEVPTPKGSVFFGEPDPIVLVAGPCSVENEEMIVET
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEECCCCCEEEEECCCCCCCHHHHHHH
AQRVAAAGASFLRGGAYKPRTSPYAFQGHGESALGLLAAAREASGLGIITEVMDTADVEK
HHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VAEVADVLQIGARNMQNFPLLKAAGAQPKPVLLKRGLSATIDEWLMAAEYILAAGNSNVI
HHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEE
LCERGIRTFDRQHLRNTLDLAAVAVLRTLTHLPIMVDPSHGTGWARFVPALAKAAIAVGT
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHCCC
DSLMIEVHPNPAKALSDGPQSLTPDQFDALTQELGVIGQAVGRWPQALAAATA
CEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]