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The map label for this gene is pabB [H]

Identifier: 158338461

GI number: 158338461

Start: 5421701

End: 5423113

Strand: Direct

Name: pabB [H]

Synonym: AM1_5363

Alternate gene names: 158338461

Gene position: 5421701-5423113 (Clockwise)

Preceding gene: 158338460

Following gene: 158338462

Centisome position: 83.36

GC content: 48.05

Gene sequence:

>1413_bases
ATGGACGAATTAAAGCCTTGGTATTGGCGATCGCAGCCACTACTCGAACGTAGCGGTACAGATATTTTTGCAGCCTTATT
TGGAGGGCAAGGGATCGCAACCCTGCTCGAAAGCCCTTATCCCCATCCCCTCGGTCAATACTCCATTTGCGCAGGCGGCC
CTCGAAGTGAGGCTGGCGATTTACGCTTATGGACACCAGAATTAGGGCGAATCTTACCGTTCTTGGAACACCAGCTACAA
CTTAAAAAGCCTTTAGCCCCAGATGGAATCCCTGATGACTTGCCCTTTCAAGGTGGGTGGTTAGGGTGGCTGGGGTATGA
CCTCGCTTGGGAAATCGAACGTTTACCCCACCTTAAACCTGATCCCCTGCCATTCCCTGTAGCCTTTTGGTACGAACCTG
AAAACTTTGCGATTTTGGATCATCAACAGCAAATCCTCTGGCTTGCAGCCAGCGATCCCCACCATTTAGATCACCTAGAA
CACCAGCTAGTATCCTACACTCCACATCCAATCATTCCATCATTTAAGGCAATAGACTTTCAGTTTCTGACAAATCAAGT
TGAGTATGAAGCGATGGTACGACAGGCCTTAGCCCATATTCAGGCTGGAGACATTTTCCAGGCCAATCTCTCCACTCGTT
TTTCGGTCAAGGCCGACGCCGATCCCTGGCAGCTCTACCAGCAACTGCAAACGATCAATCCCTCTCCCTTTGCCAGCTAT
TGGCAAACTCCATGGGGATCGGTCGTCAGTTGTTCACCAGAACGGCTTGTTCGACTTAAAGGAACACAAGCCGAGACTCG
TCCAATTGCTGGGACTCGCGCCCGGGGAATCACCCTCGAAGAGGATCAACAATTAGCTCATGCCTTAAAGGAGAACTTAA
AAGAAAGAGCTGAGCATACCATGCTAGTGGATCTTGAACGTAATGACCTCGGTCGAGTCTGTAACTGGGGATCAGTTGCC
GTAAATGAATTCCTAGCCCTTGAATACTACAGTCATGTCATTCATCTAGTTAGCAATATTGTTGGTACCCTGCGACCCAA
TCGTTCTGCGGTTGAGTTGATTCGATCAGTCTTCCCAGGAGGTACCATTACTGGCTGCCCTAAGGTCCGGTGTATGGAAA
TTATTGAAACGCTAGAACCTTATCGACGGAGTTTATTCTATGGATCCTGTGGGTATTTAGACTATCGGGGGCAGCTAGAT
CTGAACATTTTAATCCGAACCTTACTGATTACTCCCATACATCCTCCTAGCAGTGACCCCAAAAGTTCCATCCAGTCTTC
TATGATTTGGGGACAAGTGGGGGCTGGGATTGTAGCCGATAGTGATCCTGAGCAAGAATGGTTTGAATCTTTACAAAAAG
CTAAAGCTCAAGTGGAAGCCATTCAAGCCGTAAGTTCAGTCAATCTAGTTTGA

Upstream 100 bases:

>100_bases
CGGCTAATGGATCAGTTGGCGTTAGTTTTAGTCGTCTTGGTTTGTGGCTTACGGATCTGGGTCGGAACGCTTCCCTAAAT
CAATACCGTTAATATCCGAC

Downstream 100 bases:

>100_bases
TTATTTAGAAGTAATTTCTTAAAAATGTGTTGGGTAAGGAGTTTAGTTTAAGACTGAGTAAATCTACTCAAAAAGCAGTC
GACATTTCGCAAAGGACGTC

Product: anthranilate synthase component I-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MDELKPWYWRSQPLLERSGTDIFAALFGGQGIATLLESPYPHPLGQYSICAGGPRSEAGDLRLWTPELGRILPFLEHQLQ
LKKPLAPDGIPDDLPFQGGWLGWLGYDLAWEIERLPHLKPDPLPFPVAFWYEPENFAILDHQQQILWLAASDPHHLDHLE
HQLVSYTPHPIIPSFKAIDFQFLTNQVEYEAMVRQALAHIQAGDIFQANLSTRFSVKADADPWQLYQQLQTINPSPFASY
WQTPWGSVVSCSPERLVRLKGTQAETRPIAGTRARGITLEEDQQLAHALKENLKERAEHTMLVDLERNDLGRVCNWGSVA
VNEFLALEYYSHVIHLVSNIVGTLRPNRSAVELIRSVFPGGTITGCPKVRCMEIIETLEPYRRSLFYGSCGYLDYRGQLD
LNILIRTLLITPIHPPSSDPKSSIQSSMIWGQVGAGIVADSDPEQEWFESLQKAKAQVEAIQAVSSVNLV

Sequences:

>Translated_470_residues
MDELKPWYWRSQPLLERSGTDIFAALFGGQGIATLLESPYPHPLGQYSICAGGPRSEAGDLRLWTPELGRILPFLEHQLQ
LKKPLAPDGIPDDLPFQGGWLGWLGYDLAWEIERLPHLKPDPLPFPVAFWYEPENFAILDHQQQILWLAASDPHHLDHLE
HQLVSYTPHPIIPSFKAIDFQFLTNQVEYEAMVRQALAHIQAGDIFQANLSTRFSVKADADPWQLYQQLQTINPSPFASY
WQTPWGSVVSCSPERLVRLKGTQAETRPIAGTRARGITLEEDQQLAHALKENLKERAEHTMLVDLERNDLGRVCNWGSVA
VNEFLALEYYSHVIHLVSNIVGTLRPNRSAVELIRSVFPGGTITGCPKVRCMEIIETLEPYRRSLFYGSCGYLDYRGQLD
LNILIRTLLITPIHPPSSDPKSSIQSSMIWGQVGAGIVADSDPEQEWFESLQKAKAQVEAIQAVSSVNLV
>Mature_470_residues
MDELKPWYWRSQPLLERSGTDIFAALFGGQGIATLLESPYPHPLGQYSICAGGPRSEAGDLRLWTPELGRILPFLEHQLQ
LKKPLAPDGIPDDLPFQGGWLGWLGYDLAWEIERLPHLKPDPLPFPVAFWYEPENFAILDHQQQILWLAASDPHHLDHLE
HQLVSYTPHPIIPSFKAIDFQFLTNQVEYEAMVRQALAHIQAGDIFQANLSTRFSVKADADPWQLYQQLQTINPSPFASY
WQTPWGSVVSCSPERLVRLKGTQAETRPIAGTRARGITLEEDQQLAHALKENLKERAEHTMLVDLERNDLGRVCNWGSVA
VNEFLALEYYSHVIHLVSNIVGTLRPNRSAVELIRSVFPGGTITGCPKVRCMEIIETLEPYRRSLFYGSCGYLDYRGQLD
LNILIRTLLITPIHPPSSDPKSSIQSSMIWGQVGAGIVADSDPEQEWFESLQKAKAQVEAIQAVSSVNLV

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:
GO:0009058: Para-aminobenzoate synthase component I / anthranilate synthase
GO:0016833: Para-aminobenzoate synthase component I / anthranilate synthase

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=366, Percent_Identity=38.2513661202186, Blast_Score=228, Evalue=5e-61,
Organism=Escherichia coli, GI1787518, Length=379, Percent_Identity=33.509234828496, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1786809, Length=280, Percent_Identity=24.6428571428571, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=409, Percent_Identity=33.2518337408313, Blast_Score=202, Evalue=7e-53,
Organism=Saccharomyces cerevisiae, GI6324361, Length=356, Percent_Identity=25.2808988764045, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR010118 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 52966; Mature: 52966

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDELKPWYWRSQPLLERSGTDIFAALFGGQGIATLLESPYPHPLGQYSICAGGPRSEAGD
CCCCCCCCCCCCCHHHHCCCEEEEEHHCCCHHHHHHCCCCCCCCCCEEEECCCCCCCCCC
LRLWTPELGRILPFLEHQLQLKKPLAPDGIPDDLPFQGGWLGWLGYDLAWEIERLPHLKP
EEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
DPLPFPVAFWYEPENFAILDHQQQILWLAASDPHHLDHLEHQLVSYTPHPIIPSFKAIDF
CCCCCCEEEEECCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHH
QFLTNQVEYEAMVRQALAHIQAGDIFQANLSTRFSVKADADPWQLYQQLQTINPSPFASY
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHCCCCCCHHH
WQTPWGSVVSCSPERLVRLKGTQAETRPIAGTRARGITLEEDQQLAHALKENLKERAEHT
HCCCCCCEEECCHHHHEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCE
MLVDLERNDLGRVCNWGSVAVNEFLALEYYSHVIHLVSNIVGTLRPNRSAVELIRSVFPG
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
GTITGCPKVRCMEIIETLEPYRRSLFYGSCGYLDYRGQLDLNILIRTLLITPIHPPSSDP
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHCCCCCCCCCH
KSSIQSSMIWGQVGAGIVADSDPEQEWFESLQKAKAQVEAIQAVSSVNLV
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDELKPWYWRSQPLLERSGTDIFAALFGGQGIATLLESPYPHPLGQYSICAGGPRSEAGD
CCCCCCCCCCCCCHHHHCCCEEEEEHHCCCHHHHHHCCCCCCCCCCEEEECCCCCCCCCC
LRLWTPELGRILPFLEHQLQLKKPLAPDGIPDDLPFQGGWLGWLGYDLAWEIERLPHLKP
EEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
DPLPFPVAFWYEPENFAILDHQQQILWLAASDPHHLDHLEHQLVSYTPHPIIPSFKAIDF
CCCCCCEEEEECCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHH
QFLTNQVEYEAMVRQALAHIQAGDIFQANLSTRFSVKADADPWQLYQQLQTINPSPFASY
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHCCCCCCHHH
WQTPWGSVVSCSPERLVRLKGTQAETRPIAGTRARGITLEEDQQLAHALKENLKERAEHT
HCCCCCCEEECCHHHHEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCE
MLVDLERNDLGRVCNWGSVAVNEFLALEYYSHVIHLVSNIVGTLRPNRSAVELIRSVFPG
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
GTITGCPKVRCMEIIETLEPYRRSLFYGSCGYLDYRGQLDLNILIRTLLITPIHPPSSDP
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHCCCCCCCCCH
KSSIQSSMIWGQVGAGIVADSDPEQEWFESLQKAKAQVEAIQAVSSVNLV
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]