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The map label for this gene is yfhR [C]

Identifier: 158338336

GI number: 158338336

Start: 5298130

End: 5298828

Strand: Direct

Name: yfhR [C]

Synonym: AM1_5232

Alternate gene names: 158338336

Gene position: 5298130-5298828 (Clockwise)

Preceding gene: 158338335

Following gene: 158338337

Centisome position: 81.46

GC content: 51.36

Gene sequence:

>699_bases
ATGATTTTTCTGCCCCAGCCCGCCAGTTATCGAGATACAGACGAGGTCCTAAAGCTCCCCGTCAATGACCAAGAGCAGAT
CTCGGCCCTCTACTTTCCCAATCCCCAGGCGACCTTTACGTTGCTGTATATCCACGGCAATGCCGAAGATTTGGGAGATA
TTCGCCCTCGACTAGAACAGCTCCAACAGTCTGGCCTCAGCGTGTTTGCCTACGATTACCGAGGCTATGGCACCAGTGAT
GGACAGCCCAGTGAAAGCAATGCTTACCAGGATGCGAAACAAGCCTATACCTATCTAACCCAGGAGTTGGGGGTAAAGCC
CCAGCGGTTGTTAGTCCAGGGGCGCTCCCTGGGGGGCGGATCTGCCGTCTATTTGGCGACCCAATATCCTGTGGCAGGGG
TGATTTTAGAAAGCACATTTACATCAATCTTTCGAGTGGTGGTGCCCATCCCGATTTTTCCCTTCGATAAGTTCACCAGT
CTGGATAGACTAAAGCAAGTCAAAGCTCCTGTATTGGTGATGCATGGAGAAAACGATCAGGTGATTCCCATTGACCATGG
TAGGCAGCTGTTTGAAGCAGCGTCTGGACCCAAGCGATCCTTGTGGGTGGCAGGAGCAGGTCACAATAATTTTCCTCAAG
TCGCTGGTGAGCGGTATTTCCAGGTGTTGAAAGAGTTTCAACAGCTCGTTCTGGACTAA

Upstream 100 bases:

>100_bases
ACAAATTTTGCTAGGGTCCTTTAGTTGGCCCAGATTGATTCTGGCTCCTTTGCTGATCTACGTTTGCGTTGGGCTGTACG
TCTTTTTCAGGGCAGACAGC

Downstream 100 bases:

>100_bases
GTAGCAGTGCAGCACATCGAAACCTTCGGTTTATTTATCCCTTTGACGTCAATGCTCGGGGGTGGATCCGTTGGTTTCAG
GGTAAAAATGGGGCAGACTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MIFLPQPASYRDTDEVLKLPVNDQEQISALYFPNPQATFTLLYIHGNAEDLGDIRPRLEQLQQSGLSVFAYDYRGYGTSD
GQPSESNAYQDAKQAYTYLTQELGVKPQRLLVQGRSLGGGSAVYLATQYPVAGVILESTFTSIFRVVVPIPIFPFDKFTS
LDRLKQVKAPVLVMHGENDQVIPIDHGRQLFEAASGPKRSLWVAGAGHNNFPQVAGERYFQVLKEFQQLVLD

Sequences:

>Translated_232_residues
MIFLPQPASYRDTDEVLKLPVNDQEQISALYFPNPQATFTLLYIHGNAEDLGDIRPRLEQLQQSGLSVFAYDYRGYGTSD
GQPSESNAYQDAKQAYTYLTQELGVKPQRLLVQGRSLGGGSAVYLATQYPVAGVILESTFTSIFRVVVPIPIFPFDKFTS
LDRLKQVKAPVLVMHGENDQVIPIDHGRQLFEAASGPKRSLWVAGAGHNNFPQVAGERYFQVLKEFQQLVLD
>Mature_232_residues
MIFLPQPASYRDTDEVLKLPVNDQEQISALYFPNPQATFTLLYIHGNAEDLGDIRPRLEQLQQSGLSVFAYDYRGYGTSD
GQPSESNAYQDAKQAYTYLTQELGVKPQRLLVQGRSLGGGSAVYLATQYPVAGVILESTFTSIFRVVVPIPIFPFDKFTS
LDRLKQVKAPVLVMHGENDQVIPIDHGRQLFEAASGPKRSLWVAGAGHNNFPQVAGERYFQVLKEFQQLVLD

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI71051602, Length=224, Percent_Identity=37.0535714285714, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI71051600, Length=224, Percent_Identity=37.0535714285714, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI151301175, Length=199, Percent_Identity=39.6984924623116, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI194306564, Length=223, Percent_Identity=35.8744394618834, Blast_Score=144, Evalue=7e-35,
Organism=Homo sapiens, GI194306562, Length=197, Percent_Identity=37.0558375634518, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI49355781, Length=206, Percent_Identity=31.0679611650485, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI32451492, Length=186, Percent_Identity=29.0322580645161, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI32528310, Length=186, Percent_Identity=29.0322580645161, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI109689718, Length=187, Percent_Identity=34.2245989304813, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI24308097, Length=187, Percent_Identity=34.2245989304813, Blast_Score=85, Evalue=4e-17,
Organism=Escherichia coli, GI226510965, Length=239, Percent_Identity=28.0334728033473, Blast_Score=98, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988362, Length=200, Percent_Identity=38.5, Blast_Score=141, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71997133, Length=227, Percent_Identity=30.8370044052863, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71985392, Length=207, Percent_Identity=32.8502415458937, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71985387, Length=204, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17532877, Length=192, Percent_Identity=34.375, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17566318, Length=203, Percent_Identity=30.5418719211823, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25143554, Length=158, Percent_Identity=35.4430379746835, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324009, Length=226, Percent_Identity=31.858407079646, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI281362521, Length=209, Percent_Identity=37.3205741626794, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281362519, Length=209, Percent_Identity=37.3205741626794, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI28571878, Length=209, Percent_Identity=37.3205741626794, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI17137566, Length=247, Percent_Identity=28.7449392712551, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24655467, Length=227, Percent_Identity=28.1938325991189, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24655464, Length=227, Percent_Identity=28.1938325991189, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 25900; Mature: 25900

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFLPQPASYRDTDEVLKLPVNDQEQISALYFPNPQATFTLLYIHGNAEDLGDIRPRLEQ
CEECCCCCCCCCHHHHEECCCCCHHHEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHH
LQQSGLSVFAYDYRGYGTSDGQPSESNAYQDAKQAYTYLTQELGVKPQRLLVQGRSLGGG
HHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCCC
SAVYLATQYPVAGVILESTFTSIFRVVVPIPIFPFDKFTSLDRLKQVKAPVLVMHGENDQ
CEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCC
VIPIDHGRQLFEAASGPKRSLWVAGAGHNNFPQVAGERYFQVLKEFQQLVLD
EEECCCCHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIFLPQPASYRDTDEVLKLPVNDQEQISALYFPNPQATFTLLYIHGNAEDLGDIRPRLEQ
CEECCCCCCCCCHHHHEECCCCCHHHEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHH
LQQSGLSVFAYDYRGYGTSDGQPSESNAYQDAKQAYTYLTQELGVKPQRLLVQGRSLGGG
HHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCCC
SAVYLATQYPVAGVILESTFTSIFRVVVPIPIFPFDKFTSLDRLKQVKAPVLVMHGENDQ
CEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCC
VIPIDHGRQLFEAASGPKRSLWVAGAGHNNFPQVAGERYFQVLKEFQQLVLD
EEECCCCHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]