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The map label for this gene is 158338322

Identifier: 158338322

GI number: 158338322

Start: 5284073

End: 5285284

Strand: Reverse

Name: 158338322

Synonym: AM1_5218

Alternate gene names: NA

Gene position: 5285284-5284073 (Counterclockwise)

Preceding gene: 158338328

Following gene: 158338317

Centisome position: 81.27

GC content: 53.05

Gene sequence:

>1212_bases
ATGAGTAATTCTCGACCCTATGACGTCGTCCTCTACGGAGCGAGCGGGTTTACTGGGCGGCAGACGGTTGAATATTTTGC
CCAAAATGTGGGCGAGCAAATCCGATGGGCGATCGCAGGTCGGAATCGCCAAAAACTTGAGCAGGTTAAAGCGGACTGTG
CGGCTGCGGTGGATGTTTTGGTGGCCGATAGTCAGGACCAAGAAGGACTAGATACCATTGCGGGACAGGCCCACGTCATT
CTCAATACGGCGGGTCCATTTGCCTTATATGGGGATTTCTTGGTGGATGCCTGTGTCCGTAAGCAAACTCACTATGTCGA
TATCACCGGCGAAACCCCTTGGGTCAAATCATTGATCCAGCGCTACCATGCCAAAGCTTCAGCGGATGGCACCCGCATTA
TTCCCTTCTGTGGGTTTGATTCGGTGCCCTCGGACCTCGGCACCTACTTAGTGGTGCGGTTTATGCAGCAAGAATTGGGC
GTCTCCTGTCGACAAGTCAAAGCCTGCTTCAAAGCGGCAGGCGGCTTTAATGGCGGCACCTTGGCGTCGGCCATCAACTT
AATGCAGTCAGGGGAGTCCTCCCAAATGGCGGACCCCTATTTGCTCAATCCCCAAGAAGAGTCCCCTCCCGATATCGTCC
CCTTGAGCCAAGACCCCAAAGGACCGCAGTATGACTCAGACTTGCAGACCTGGATTGCCCCTTTCTTTATGGGACCTGTC
AATACTCGTGTGGTCAGACGTAGTAGTGCCCTCTTCGATCAATGGCAAGAATCCTACGGTCCCCATTTTGCCTATCAGGA
ATATCTAAAGTTCGGTGGACCGTTAGCTGCCTTTGGCACTACATTGGCAACAGGAGTATTTGGTTTGGCCTTAAGCCAAG
GGTGGGCCAGAACGCTGCTACAGTCCCGACTGCCTCAACCCGGCAGCGGCCCTTCGACCCAGGTGATGGATGAAGGCTGG
TTCCGGTGTGAACTGATCGGACAGGCTAGCAATGGTCAACAGGTACGGGGCCTGATTTACAATCAAGGCGATCCGGGGAA
CCGCTCAACGGTAAAGTTTTTATGTGAGTCGGCATTGTGTTTAGCGACTCAGGCCGATCAGTTACCCGGTAAACACCGTG
GTGGCATATTAACTCCATCAACTGGATTAGGAGATATCCTTGCAGATCGTCTACGCAGTGCTGGGACTAAGATTGAACTA
GCGATTCGCTAA

Upstream 100 bases:

>100_bases
AGGTTTGGAAAATCCTGACCCTAGCCTTAAGATGATTTTCCTTCAACCTAGCAAAAGGTTAATCGGTATACGATTAAAGA
GCCGTTGACTTGGACCCTGT

Downstream 100 bases:

>100_bases
AACTAATCTGATACTGAAATATTCAGTAGACTCCAGTCGGACCAGCCATTATTTCACCGTTGCGCGAAAACGGACTGCAC
CATATGATGTGGCAGGATTT

Product: saccharopine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSNSRPYDVVLYGASGFTGRQTVEYFAQNVGEQIRWAIAGRNRQKLEQVKADCAAAVDVLVADSQDQEGLDTIAGQAHVI
LNTAGPFALYGDFLVDACVRKQTHYVDITGETPWVKSLIQRYHAKASADGTRIIPFCGFDSVPSDLGTYLVVRFMQQELG
VSCRQVKACFKAAGGFNGGTLASAINLMQSGESSQMADPYLLNPQEESPPDIVPLSQDPKGPQYDSDLQTWIAPFFMGPV
NTRVVRRSSALFDQWQESYGPHFAYQEYLKFGGPLAAFGTTLATGVFGLALSQGWARTLLQSRLPQPGSGPSTQVMDEGW
FRCELIGQASNGQQVRGLIYNQGDPGNRSTVKFLCESALCLATQADQLPGKHRGGILTPSTGLGDILADRLRSAGTKIEL
AIR

Sequences:

>Translated_403_residues
MSNSRPYDVVLYGASGFTGRQTVEYFAQNVGEQIRWAIAGRNRQKLEQVKADCAAAVDVLVADSQDQEGLDTIAGQAHVI
LNTAGPFALYGDFLVDACVRKQTHYVDITGETPWVKSLIQRYHAKASADGTRIIPFCGFDSVPSDLGTYLVVRFMQQELG
VSCRQVKACFKAAGGFNGGTLASAINLMQSGESSQMADPYLLNPQEESPPDIVPLSQDPKGPQYDSDLQTWIAPFFMGPV
NTRVVRRSSALFDQWQESYGPHFAYQEYLKFGGPLAAFGTTLATGVFGLALSQGWARTLLQSRLPQPGSGPSTQVMDEGW
FRCELIGQASNGQQVRGLIYNQGDPGNRSTVKFLCESALCLATQADQLPGKHRGGILTPSTGLGDILADRLRSAGTKIEL
AIR
>Mature_402_residues
SNSRPYDVVLYGASGFTGRQTVEYFAQNVGEQIRWAIAGRNRQKLEQVKADCAAAVDVLVADSQDQEGLDTIAGQAHVIL
NTAGPFALYGDFLVDACVRKQTHYVDITGETPWVKSLIQRYHAKASADGTRIIPFCGFDSVPSDLGTYLVVRFMQQELGV
SCRQVKACFKAAGGFNGGTLASAINLMQSGESSQMADPYLLNPQEESPPDIVPLSQDPKGPQYDSDLQTWIAPFFMGPVN
TRVVRRSSALFDQWQESYGPHFAYQEYLKFGGPLAAFGTTLATGVFGLALSQGWARTLLQSRLPQPGSGPSTQVMDEGWF
RCELIGQASNGQQVRGLIYNQGDPGNRSTVKFLCESALCLATQADQLPGKHRGGILTPSTGLGDILADRLRSAGTKIELA
IR

Specific function: Unknown

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=439, Percent_Identity=27.7904328018223, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17560066, Length=431, Percent_Identity=28.538283062645, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI32567112, Length=399, Percent_Identity=28.5714285714286, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71991033, Length=162, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24644140, Length=425, Percent_Identity=29.1764705882353, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24644142, Length=425, Percent_Identity=29.1764705882353, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21356081, Length=425, Percent_Identity=29.1764705882353, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646278, Length=417, Percent_Identity=28.0575539568345, Blast_Score=135, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 43702; Mature: 43571

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSRPYDVVLYGASGFTGRQTVEYFAQNVGEQIRWAIAGRNRQKLEQVKADCAAAVDVL
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEHHHCCCCHHHHHHHHHHHHHHHHHH
VADSQDQEGLDTIAGQAHVILNTAGPFALYGDFLVDACVRKQTHYVDITGETPWVKSLIQ
EECCCCCCCHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
RYHAKASADGTRIIPFCGFDSVPSDLGTYLVVRFMQQELGVSCRQVKACFKAAGGFNGGT
HHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHH
LASAINLMQSGESSQMADPYLLNPQEESPPDIVPLSQDPKGPQYDSDLQTWIAPFFMGPV
HHHHHHHHHCCCCCCCCCCEEECCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCC
NTRVVRRSSALFDQWQESYGPHFAYQEYLKFGGPLAAFGTTLATGVFGLALSQGWARTLL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QSRLPQPGSGPSTQVMDEGWFRCELIGQASNGQQVRGLIYNQGDPGNRSTVKFLCESALC
HHHCCCCCCCCCCCHHHCCCEEEEEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
LATQADQLPGKHRGGILTPSTGLGDILADRLRSAGTKIELAIR
HHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEEEC
>Mature Secondary Structure 
SNSRPYDVVLYGASGFTGRQTVEYFAQNVGEQIRWAIAGRNRQKLEQVKADCAAAVDVL
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEHHHCCCCHHHHHHHHHHHHHHHHHH
VADSQDQEGLDTIAGQAHVILNTAGPFALYGDFLVDACVRKQTHYVDITGETPWVKSLIQ
EECCCCCCCHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
RYHAKASADGTRIIPFCGFDSVPSDLGTYLVVRFMQQELGVSCRQVKACFKAAGGFNGGT
HHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHH
LASAINLMQSGESSQMADPYLLNPQEESPPDIVPLSQDPKGPQYDSDLQTWIAPFFMGPV
HHHHHHHHHCCCCCCCCCCEEECCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCC
NTRVVRRSSALFDQWQESYGPHFAYQEYLKFGGPLAAFGTTLATGVFGLALSQGWARTLL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QSRLPQPGSGPSTQVMDEGWFRCELIGQASNGQQVRGLIYNQGDPGNRSTVKFLCESALC
HHHCCCCCCCCCCCHHHCCCEEEEEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
LATQADQLPGKHRGGILTPSTGLGDILADRLRSAGTKIELAIR
HHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]