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The map label for this gene is mreC [H]

Identifier: 158338292

GI number: 158338292

Start: 5252085

End: 5252861

Strand: Reverse

Name: mreC [H]

Synonym: AM1_5188

Alternate gene names: 158338292

Gene position: 5252861-5252085 (Counterclockwise)

Preceding gene: 158338293

Following gene: 158338291

Centisome position: 80.77

GC content: 50.58

Gene sequence:

>777_bases
ATGCTTTTTCTGTTTCGCTGGTGGGAACGGTATCGTTTAGGGTTAATCCTAGCTATTTTATGCCTAGGAGGAGCGTGGGT
ATTTAGCCGTTCTCAAGGGGTGGGCTTGCTGGAAATCTTTCGGTTTGCTCATCGACCGGTGCAGCCGGATGCCGTTAGGC
AAAAAGAGCTGGTGGATGCCCAAACAAAACAGCTCCGTCAGCAACTGGCTGATCTGGAATCCCGCAATCAGACCCTCCAG
GAGCTGGTTGATCACAAAAGTGTGAAAAGCAAGCAAGCGATCGCAGTTTCAATACTGGGGCGCAGTGGGGATAATTGGTG
GCAACAGTTAACCCTGAGCAAAGGCGAGAATCACGGCATTAAAGTGGGTTCCGTGGTATTCGCGCCGGGGGGATTAGTAG
GGCGAGTGACCGCTGTTTCTCAAAATACCAGTCGAGTCTTATTAGTTACCGATCCAACAAGCCGCATTGGGGTGATTGTT
ACCCGTAGCCGCCACATGGGCATCTTTCAAGGCCAGTCGGGCACCGAAGCCCTAATCACCTTTTTTGATAAGGATCCGGA
CGTGAAGGTGGGGGATGCGGTGGTCACCTCTTCCCTCAGTCGCCTATTCCCTCCAGGGCTGCCAGTCGGTAAAATTAAGA
CTTTGAAATTAGAGCAAAATTACAATCCTCAGGCCATTGTTGAATTGGCAGTCCCGATTAGCAAGTTGGAATGGGTTAGC
GTATACCTGAATGATCAAACCTCTCTCCTTCAGAAAACAGTCCCCGCTTCCCCTTAA

Upstream 100 bases:

>100_bases
TAATGCCTCTATACAATCAAGCCAGTTATTGAGTGCTGGGTTGGGGGGCTGATTCAGTTCTCAGGCCGGTCGGGGGATCC
GTTCTTTAGTTTGATCGTCA

Downstream 100 bases:

>100_bases
TCTTTGGAATGCTGCCATCGTGGTTGGATCCGTGATGATCTGTGCCTTGATGTTGCTGTTCAGGTTGCCGGTCATGGTGC
TATCAGGGGTGGGGCCGAAT

Product: rod shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLFLFRWWERYRLGLILAILCLGGAWVFSRSQGVGLLEIFRFAHRPVQPDAVRQKELVDAQTKQLRQQLADLESRNQTLQ
ELVDHKSVKSKQAIAVSILGRSGDNWWQQLTLSKGENHGIKVGSVVFAPGGLVGRVTAVSQNTSRVLLVTDPTSRIGVIV
TRSRHMGIFQGQSGTEALITFFDKDPDVKVGDAVVTSSLSRLFPPGLPVGKIKTLKLEQNYNPQAIVELAVPISKLEWVS
VYLNDQTSLLQKTVPASP

Sequences:

>Translated_258_residues
MLFLFRWWERYRLGLILAILCLGGAWVFSRSQGVGLLEIFRFAHRPVQPDAVRQKELVDAQTKQLRQQLADLESRNQTLQ
ELVDHKSVKSKQAIAVSILGRSGDNWWQQLTLSKGENHGIKVGSVVFAPGGLVGRVTAVSQNTSRVLLVTDPTSRIGVIV
TRSRHMGIFQGQSGTEALITFFDKDPDVKVGDAVVTSSLSRLFPPGLPVGKIKTLKLEQNYNPQAIVELAVPISKLEWVS
VYLNDQTSLLQKTVPASP
>Mature_258_residues
MLFLFRWWERYRLGLILAILCLGGAWVFSRSQGVGLLEIFRFAHRPVQPDAVRQKELVDAQTKQLRQQLADLESRNQTLQ
ELVDHKSVKSKQAIAVSILGRSGDNWWQQLTLSKGENHGIKVGSVVFAPGGLVGRVTAVSQNTSRVLLVTDPTSRIGVIV
TRSRHMGIFQGQSGTEALITFFDKDPDVKVGDAVVTSSLSRLFPPGLPVGKIKTLKLEQNYNPQAIVELAVPISKLEWVS
VYLNDQTSLLQKTVPASP

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:
GO:0008360: Rod shape-determining protein MreC, putative

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family [H]

Homologues:

Organism=Escherichia coli, GI1789648, Length=175, Percent_Identity=29.1428571428571, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007221
- InterPro:   IPR005223 [H]

Pfam domain/function: PF04085 MreC [H]

EC number: NA

Molecular weight: Translated: 28579; Mature: 28579

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFLFRWWERYRLGLILAILCLGGAWVFSRSQGVGLLEIFRFAHRPVQPDAVRQKELVDA
CEEEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
QTKQLRQQLADLESRNQTLQELVDHKSVKSKQAIAVSILGRSGDNWWQQLTLSKGENHGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCE
KVGSVVFAPGGLVGRVTAVSQNTSRVLLVTDPTSRIGVIVTRSRHMGIFQGQSGTEALIT
EEEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCCEEECCCCCEEEEE
FFDKDPDVKVGDAVVTSSLSRLFPPGLPVGKIKTLKLEQNYNPQAIVELAVPISKLEWVS
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEE
VYLNDQTSLLQKTVPASP
EEECCHHHHHHHCCCCCC
>Mature Secondary Structure
MLFLFRWWERYRLGLILAILCLGGAWVFSRSQGVGLLEIFRFAHRPVQPDAVRQKELVDA
CEEEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
QTKQLRQQLADLESRNQTLQELVDHKSVKSKQAIAVSILGRSGDNWWQQLTLSKGENHGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCE
KVGSVVFAPGGLVGRVTAVSQNTSRVLLVTDPTSRIGVIVTRSRHMGIFQGQSGTEALIT
EEEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCCEEECCCCCEEEEE
FFDKDPDVKVGDAVVTSSLSRLFPPGLPVGKIKTLKLEQNYNPQAIVELAVPISKLEWVS
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEE
VYLNDQTSLLQKTVPASP
EEECCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377 [H]