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The map label for this gene is tldD [C]

Identifier: 158338264

GI number: 158338264

Start: 5223930

End: 5225369

Strand: Reverse

Name: tldD [C]

Synonym: AM1_5160

Alternate gene names: 158338264

Gene position: 5225369-5223930 (Counterclockwise)

Preceding gene: 158338269

Following gene: 158338263

Centisome position: 80.34

GC content: 53.26

Gene sequence:

>1440_bases
ATGAAGTTTGACCTTCATCAGGCTCTCAACACCTTAGATATCAACGCGGATTGGGTGGGCCTCCGTCAGGTGAATGAGAA
GACCACCACCCATGCCGTTCGTGACGGGCGACCCCAAAGTAATGGTCGCGATTTTACCCAGGGCGTGATGGTGGAGGTCC
TTGCTGAAGGCCAGTTTGGTTATGCCGCCACCAACCGCTTAGACCCAGCTAGTTTACAAGGGGCCGCCGAGCAGGCGTAT
CAACAAGCGATCGCAACCTCTAAATGGGCGGTCCACTCCTTTACTCCCGAGGTGCGTCCCAAGGCCGTGGGCCAATACCA
ATCTCCCTTTCAGCAGCCCTTGGACCTGATTAGCGTTGCCGATCAGCTGGATCTGTTGGTGAAAGTCTGTGACACCCTCC
ACGTCTCCGACCAAATTGTTAAAACCAGCGCCTTTACCCAAACCTTAGAAACCGAACAGATCTTCGTTAGCAGTAATGGT
ACGGATACCCACCAAACCTTTAGGTTTGTGATCACCAATTATGAAGCGACAGCCCAGGACGGCAGCATTATCCAAAAGCG
CACCGATAATGGTCCCTTAGCCCGCTGTTATCAAGCTGGCTCTGAAGTGTTTGACCCCGACCAGGTGCTCGCCCGTGCCC
AGCAAGTGGGGGAACAGGCCATTGCCCTACTGGCTGCTGAAGACTGCCCCACAGCTACCACCACCTTGGTACTGGCACCA
GACCAAATGATGCTACAAATTCATGAGAGTATCGGCCATCCTTTAGAGCTGGATCGGATCCTCGGAGATGAGCGCAATTA
TGCCGGGTCTAGCTTTGTAAAGCTCTCTGATTTTGGTCATCTGGTGTATGGGTCGCCACTGATGAATATTACCTTTGACC
CTACAGTCCCCGGTGAATTTGCGGGCTATGCCTTTGATGATGCCGGGATGCCTGCCCAGCGAGAGTATCTGATCAAAGAA
GGACTGCTACTGCGGGGACTAGGGAGCTTAGAAAGCCAAGCCAGAGCCCAGGTGCCTGGGGTGGCTAACTTCCGAGCCCG
TTCCTGGAATCGAGCCCCCATTGACCGGATGGCCAATCTAAATCTAGAACCGGGCCAATCCTCCTTTGAGGAAATGATCA
GCAATATCGAATCTGGGGTCTATATGGAGGCCAATCGATCCTGGTCCATTGATGACTATCGCAATAAGTTCCAGTTTGGC
TGTGAGTATGCCCGCCTAATCGAAAACGGCAAGCTGACCAAGGTCTTACGCAACCCCAACTACCGAGGCATTACTAATCA
ATTCTGGGGGAACCTGGCTCAAGTGGGGGATGCCAGCACCTTTGCCATGTATGGCACCCCCTACTGTGGCAAGGGCGAAC
CCAATCAATGCATCCGGGTCGGCCATGCCTCACCCACCTGTGTATTTAAAGAAATCGAAGTATTTGGAGGAGCCGCATGA

Upstream 100 bases:

>100_bases
TCCATGATGAAGCGACACTCATTTTAATAAAGAGCTGTTGTGCCCTCTTAGGAAACGTTAGACTAGCGCTTACGCACCTT
ATTTATCGAGCAATATAGAT

Downstream 100 bases:

>100_bases
GCACCAGTGTTGCCACCCACCCCACCGAAACCCTGGCGGCTTGGGAGTCCACCTTTAATCAGTTGGCCGACCTGCTGTTG
GATAACTTACAGGCGGGAGA

Product: modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MKFDLHQALNTLDINADWVGLRQVNEKTTTHAVRDGRPQSNGRDFTQGVMVEVLAEGQFGYAATNRLDPASLQGAAEQAY
QQAIATSKWAVHSFTPEVRPKAVGQYQSPFQQPLDLISVADQLDLLVKVCDTLHVSDQIVKTSAFTQTLETEQIFVSSNG
TDTHQTFRFVITNYEATAQDGSIIQKRTDNGPLARCYQAGSEVFDPDQVLARAQQVGEQAIALLAAEDCPTATTTLVLAP
DQMMLQIHESIGHPLELDRILGDERNYAGSSFVKLSDFGHLVYGSPLMNITFDPTVPGEFAGYAFDDAGMPAQREYLIKE
GLLLRGLGSLESQARAQVPGVANFRARSWNRAPIDRMANLNLEPGQSSFEEMISNIESGVYMEANRSWSIDDYRNKFQFG
CEYARLIENGKLTKVLRNPNYRGITNQFWGNLAQVGDASTFAMYGTPYCGKGEPNQCIRVGHASPTCVFKEIEVFGGAA

Sequences:

>Translated_479_residues
MKFDLHQALNTLDINADWVGLRQVNEKTTTHAVRDGRPQSNGRDFTQGVMVEVLAEGQFGYAATNRLDPASLQGAAEQAY
QQAIATSKWAVHSFTPEVRPKAVGQYQSPFQQPLDLISVADQLDLLVKVCDTLHVSDQIVKTSAFTQTLETEQIFVSSNG
TDTHQTFRFVITNYEATAQDGSIIQKRTDNGPLARCYQAGSEVFDPDQVLARAQQVGEQAIALLAAEDCPTATTTLVLAP
DQMMLQIHESIGHPLELDRILGDERNYAGSSFVKLSDFGHLVYGSPLMNITFDPTVPGEFAGYAFDDAGMPAQREYLIKE
GLLLRGLGSLESQARAQVPGVANFRARSWNRAPIDRMANLNLEPGQSSFEEMISNIESGVYMEANRSWSIDDYRNKFQFG
CEYARLIENGKLTKVLRNPNYRGITNQFWGNLAQVGDASTFAMYGTPYCGKGEPNQCIRVGHASPTCVFKEIEVFGGAA
>Mature_479_residues
MKFDLHQALNTLDINADWVGLRQVNEKTTTHAVRDGRPQSNGRDFTQGVMVEVLAEGQFGYAATNRLDPASLQGAAEQAY
QQAIATSKWAVHSFTPEVRPKAVGQYQSPFQQPLDLISVADQLDLLVKVCDTLHVSDQIVKTSAFTQTLETEQIFVSSNG
TDTHQTFRFVITNYEATAQDGSIIQKRTDNGPLARCYQAGSEVFDPDQVLARAQQVGEQAIALLAAEDCPTATTTLVLAP
DQMMLQIHESIGHPLELDRILGDERNYAGSSFVKLSDFGHLVYGSPLMNITFDPTVPGEFAGYAFDDAGMPAQREYLIKE
GLLLRGLGSLESQARAQVPGVANFRARSWNRAPIDRMANLNLEPGQSSFEEMISNIESGVYMEANRSWSIDDYRNKFQFG
CEYARLIENGKLTKVLRNPNYRGITNQFWGNLAQVGDASTFAMYGTPYCGKGEPNQCIRVGHASPTCVFKEIEVFGGAA

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=271, Percent_Identity=30.2583025830258, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 52789; Mature: 52789

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDLHQALNTLDINADWVGLRQVNEKTTTHAVRDGRPQSNGRDFTQGVMVEVLAEGQFG
CCCCHHHHHHHCCCCCCEEEHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC
YAATNRLDPASLQGAAEQAYQQAIATSKWAVHSFTPEVRPKAVGQYQSPFQQPLDLISVA
CHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHCCCHHCHHHHHHHHHHHH
DQLDLLVKVCDTLHVSDQIVKTSAFTQTLETEQIFVSSNGTDTHQTFRFVITNYEATAQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHEEEEEEECCCCCCCC
GSIIQKRTDNGPLARCYQAGSEVFDPDQVLARAQQVGEQAIALLAAEDCPTATTTLVLAP
CCEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
DQMMLQIHESIGHPLELDRILGDERNYAGSSFVKLSDFGHLVYGSPLMNITFDPTVPGEF
HHHHHHHHHHHCCCEEHHHHHCCCCCCCCCCEEEECCCCCEEECCCEEEEEECCCCCCCC
AGYAFDDAGMPAQREYLIKEGLLLRGLGSLESQARAQVPGVANFRARSWNRAPIDRMANL
CCCEECCCCCCHHHHHHHHCCHHHHCCCCHHHHHHHCCCCCCCHHCCCCCCCCHHHHHCC
NLEPGQSSFEEMISNIESGVYMEANRSWSIDDYRNKFQFGCEYARLIENGKLTKVLRNPN
CCCCCHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHCCCC
YRGITNQFWGNLAQVGDASTFAMYGTPYCGKGEPNQCIRVGHASPTCVFKEIEVFGGAA
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKFDLHQALNTLDINADWVGLRQVNEKTTTHAVRDGRPQSNGRDFTQGVMVEVLAEGQFG
CCCCHHHHHHHCCCCCCEEEHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC
YAATNRLDPASLQGAAEQAYQQAIATSKWAVHSFTPEVRPKAVGQYQSPFQQPLDLISVA
CHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHCCCHHCHHHHHHHHHHHH
DQLDLLVKVCDTLHVSDQIVKTSAFTQTLETEQIFVSSNGTDTHQTFRFVITNYEATAQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHEEEEEEECCCCCCCC
GSIIQKRTDNGPLARCYQAGSEVFDPDQVLARAQQVGEQAIALLAAEDCPTATTTLVLAP
CCEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
DQMMLQIHESIGHPLELDRILGDERNYAGSSFVKLSDFGHLVYGSPLMNITFDPTVPGEF
HHHHHHHHHHHCCCEEHHHHHCCCCCCCCCCEEEECCCCCEEECCCEEEEEECCCCCCCC
AGYAFDDAGMPAQREYLIKEGLLLRGLGSLESQARAQVPGVANFRARSWNRAPIDRMANL
CCCEECCCCCCHHHHHHHHCCHHHHCCCCHHHHHHHCCCCCCCHHCCCCCCCCHHHHHCC
NLEPGQSSFEEMISNIESGVYMEANRSWSIDDYRNKFQFGCEYARLIENGKLTKVLRNPN
CCCCCHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHCCCC
YRGITNQFWGNLAQVGDASTFAMYGTPYCGKGEPNQCIRVGHASPTCVFKEIEVFGGAA
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]