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The map label for this gene is recQ [H]

Identifier: 158338254

GI number: 158338254

Start: 5212149

End: 5213615

Strand: Direct

Name: recQ [H]

Synonym: AM1_5150

Alternate gene names: 158338254

Gene position: 5212149-5213615 (Clockwise)

Preceding gene: 158338253

Following gene: 158338255

Centisome position: 80.14

GC content: 52.22

Gene sequence:

>1467_bases
ATGAGGCTTGACCATTCACAGGCTTGGGATAGAGCCATCGCTGGGCTACAGAAGTTTTGGGGGTACAGTCAGTTTCGCCC
TTTACAGGGAGAGGCTGTTACCAGCCTACTGAAACACCAAGATGCCTTGGTGATGCTGCCAACTGGCTCGGGTAAATCCG
TCTGCTTTCAGCTTCCAGCACTGTTACAGTCTGGCCTAACGATTGTGATCTCTCCTTTGATTGCTCTGATGGAAGATCAA
GTGCAAGCACTCCAGGCAAAAAAGCTACCTGCTGGGATGATTCACAGCCAGCTCTCTTCTCAGAAGCGTCGGCAGACATT
GCGACAAATAGAACAGCAGCAATTACGCCTATTATATCTATCTCCCGAATCCTTGTTGAGCCCACCCATTTGGCAGCGGT
TAGGGGATCCGCACTTGCAGATTCGATGTTTAATTGTGGATGAAGCCCACTGCATTGAGCAATGGGGGAGCAGTTTTCGC
CCAGTCTATCGCCGCTTAGGGTCGATTCGGGATGCGCTATTGCCAAAGAACAGTGCCGCACCCATTACCGTAGCCGCCTA
TACGGCGACCGCTAAACCCACAACACAAGCCGCAATTCAAACCGTACTTCGACTGCATCAGCCTCAGGTTCTGAGTTGTA
GTCCCTATCGAAATAATCTAGATTTGACCGTTGAAGTGGCCTGGACCCCTGCCTGTCGGCGACAAAAACTTTTGGCATTT
ATTGGCCGACAGGCCCATTCGGCAGGACTGGTGTATACCTCTAGCCGACGTTTATGTGAGAGTTTAGCCGCTTGGTTCTG
CCAGCAACATCAGCCCACGGTGGCCTACCATGCGGGACTCAGCGCGCCTGAACGTCGCCGCATCGAAGCTCAGTGGCTTC
AGGGGAAGCTACCATTTGTGATTTGTACAAGTGCGTTTGGCATGGGAATTGATAAACCCGATGTGCGGTGGATCGCCCAC
TATCATCCCCCTTTGAGCTTAAGTGCTTATCTGCAAGAAATCGGTCGGGCTGGTCGAGACAACTTGCGATCGCAAACCCT
GCTGCTAACCAGTGAACCCACTGGTTGGCTGGATCCTCAAGATCGGCAAATGCGACAATACTTCCTCAAACAGTTGAGGG
GACAACAAGCATCCGCCCAGCGGTTGGTCCATCGACTTCCCCGGCAAGGTCATATTGACACCATCACAAAAGCCTTCCCA
GAGGCCGACCTCGCCCTAGCGCTCCTGCATCAGTCGGGTCATCTCATCTGGGAGGATCCATTTCACTTTCGAATTCTGGC
TGCTCAAGGGTTCAACCCTCCCCTCATTCCCACCAAGCTGGATATCACGGATTATCTCTACACCCGCCAATGCCGTTGGC
AATTCATTTTGCAACAGTTTGGTTTTGACCAAGAAGCGCATCACTTTCGATGCGGCCATTGTGATCGCTGCCGTTCCCGC
ACATCCAAGTCCAGATCCTTCCATTAA

Upstream 100 bases:

>100_bases
ACTTAGCCTTTAAGGGAGAGAGTGCTCCGGTTGAACAGACTTACCTTGGCAAGGACATTAGCTTCTTGGACTTTGTTACT
TCTAAGAATGTTTCCTGAAG

Downstream 100 bases:

>100_bases
GCCCCTCGTAAAGGGCCAAGGCGTTGGCTGTAATTCCCTCCAAGAAGGAAAAGTGTGGGGCTTACCCACCTCCTGAATTT
TCAGGGTTAAAAGAGGTTGT

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MRLDHSQAWDRAIAGLQKFWGYSQFRPLQGEAVTSLLKHQDALVMLPTGSGKSVCFQLPALLQSGLTIVISPLIALMEDQ
VQALQAKKLPAGMIHSQLSSQKRRQTLRQIEQQQLRLLYLSPESLLSPPIWQRLGDPHLQIRCLIVDEAHCIEQWGSSFR
PVYRRLGSIRDALLPKNSAAPITVAAYTATAKPTTQAAIQTVLRLHQPQVLSCSPYRNNLDLTVEVAWTPACRRQKLLAF
IGRQAHSAGLVYTSSRRLCESLAAWFCQQHQPTVAYHAGLSAPERRRIEAQWLQGKLPFVICTSAFGMGIDKPDVRWIAH
YHPPLSLSAYLQEIGRAGRDNLRSQTLLLTSEPTGWLDPQDRQMRQYFLKQLRGQQASAQRLVHRLPRQGHIDTITKAFP
EADLALALLHQSGHLIWEDPFHFRILAAQGFNPPLIPTKLDITDYLYTRQCRWQFILQQFGFDQEAHHFRCGHCDRCRSR
TSKSRSFH

Sequences:

>Translated_488_residues
MRLDHSQAWDRAIAGLQKFWGYSQFRPLQGEAVTSLLKHQDALVMLPTGSGKSVCFQLPALLQSGLTIVISPLIALMEDQ
VQALQAKKLPAGMIHSQLSSQKRRQTLRQIEQQQLRLLYLSPESLLSPPIWQRLGDPHLQIRCLIVDEAHCIEQWGSSFR
PVYRRLGSIRDALLPKNSAAPITVAAYTATAKPTTQAAIQTVLRLHQPQVLSCSPYRNNLDLTVEVAWTPACRRQKLLAF
IGRQAHSAGLVYTSSRRLCESLAAWFCQQHQPTVAYHAGLSAPERRRIEAQWLQGKLPFVICTSAFGMGIDKPDVRWIAH
YHPPLSLSAYLQEIGRAGRDNLRSQTLLLTSEPTGWLDPQDRQMRQYFLKQLRGQQASAQRLVHRLPRQGHIDTITKAFP
EADLALALLHQSGHLIWEDPFHFRILAAQGFNPPLIPTKLDITDYLYTRQCRWQFILQQFGFDQEAHHFRCGHCDRCRSR
TSKSRSFH
>Mature_488_residues
MRLDHSQAWDRAIAGLQKFWGYSQFRPLQGEAVTSLLKHQDALVMLPTGSGKSVCFQLPALLQSGLTIVISPLIALMEDQ
VQALQAKKLPAGMIHSQLSSQKRRQTLRQIEQQQLRLLYLSPESLLSPPIWQRLGDPHLQIRCLIVDEAHCIEQWGSSFR
PVYRRLGSIRDALLPKNSAAPITVAAYTATAKPTTQAAIQTVLRLHQPQVLSCSPYRNNLDLTVEVAWTPACRRQKLLAF
IGRQAHSAGLVYTSSRRLCESLAAWFCQQHQPTVAYHAGLSAPERRRIEAQWLQGKLPFVICTSAFGMGIDKPDVRWIAH
YHPPLSLSAYLQEIGRAGRDNLRSQTLLLTSEPTGWLDPQDRQMRQYFLKQLRGQQASAQRLVHRLPRQGHIDTITKAFP
EADLALALLHQSGHLIWEDPFHFRILAAQGFNPPLIPTKLDITDYLYTRQCRWQFILQQFGFDQEAHHFRCGHCDRCRSR
TSKSRSFH

Specific function: DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI51242943, Length=347, Percent_Identity=40.0576368876081, Blast_Score=236, Evalue=5e-62,
Organism=Homo sapiens, GI51242947, Length=347, Percent_Identity=40.0576368876081, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI148612816, Length=396, Percent_Identity=37.6262626262626, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI4557365, Length=347, Percent_Identity=37.1757925072046, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI169218196, Length=374, Percent_Identity=32.3529411764706, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI110735439, Length=374, Percent_Identity=32.3529411764706, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI14591902, Length=342, Percent_Identity=33.3333333333333, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI14591904, Length=342, Percent_Identity=33.3333333333333, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI284005309, Length=372, Percent_Identity=35.4838709677419, Blast_Score=179, Evalue=5e-45,
Organism=Escherichia coli, GI48994977, Length=388, Percent_Identity=36.8556701030928, Blast_Score=238, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17552866, Length=342, Percent_Identity=38.0116959064327, Blast_Score=227, Evalue=9e-60,
Organism=Caenorhabditis elegans, GI32564293, Length=336, Percent_Identity=34.5238095238095, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI25145561, Length=343, Percent_Identity=34.1107871720117, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI71987993, Length=340, Percent_Identity=32.3529411764706, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71987997, Length=340, Percent_Identity=32.3529411764706, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323844, Length=340, Percent_Identity=37.3529411764706, Blast_Score=212, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6324217, Length=339, Percent_Identity=23.598820058997, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24664226, Length=352, Percent_Identity=35.7954545454545, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24664230, Length=351, Percent_Identity=35.6125356125356, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI62472181, Length=351, Percent_Identity=35.6125356125356, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24646066, Length=344, Percent_Identity=35.7558139534884, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI21358123, Length=365, Percent_Identity=33.6986301369863, Blast_Score=172, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 55539; Mature: 55539

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDHSQAWDRAIAGLQKFWGYSQFRPLQGEAVTSLLKHQDALVMLPTGSGKSVCFQLPA
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
LLQSGLTIVISPLIALMEDQVQALQAKKLPAGMIHSQLSSQKRRQTLRQIEQQQLRLLYL
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
SPESLLSPPIWQRLGDPHLQIRCLIVDEAHCIEQWGSSFRPVYRRLGSIRDALLPKNSAA
CCHHHHCCHHHHHCCCCCEEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
PITVAAYTATAKPTTQAAIQTVLRLHQPQVLSCSPYRNNLDLTVEVAWTPACRRQKLLAF
CEEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEEEEECCHHHHHHHHHH
IGRQAHSAGLVYTSSRRLCESLAAWFCQQHQPTVAYHAGLSAPERRRIEAQWLQGKLPFV
HHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEE
ICTSAFGMGIDKPDVRWIAHYHPPLSLSAYLQEIGRAGRDNLRSQTLLLTSEPTGWLDPQ
EEECHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCC
DRQMRQYFLKQLRGQQASAQRLVHRLPRQGHIDTITKAFPEADLALALLHQSGHLIWEDP
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCEEEECC
FHFRILAAQGFNPPLIPTKLDITDYLYTRQCRWQFILQQFGFDQEAHHFRCGHCDRCRSR
CEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
TSKSRSFH
HCCCCCCC
>Mature Secondary Structure
MRLDHSQAWDRAIAGLQKFWGYSQFRPLQGEAVTSLLKHQDALVMLPTGSGKSVCFQLPA
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
LLQSGLTIVISPLIALMEDQVQALQAKKLPAGMIHSQLSSQKRRQTLRQIEQQQLRLLYL
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
SPESLLSPPIWQRLGDPHLQIRCLIVDEAHCIEQWGSSFRPVYRRLGSIRDALLPKNSAA
CCHHHHCCHHHHHCCCCCEEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
PITVAAYTATAKPTTQAAIQTVLRLHQPQVLSCSPYRNNLDLTVEVAWTPACRRQKLLAF
CEEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEEEEECCHHHHHHHHHH
IGRQAHSAGLVYTSSRRLCESLAAWFCQQHQPTVAYHAGLSAPERRRIEAQWLQGKLPFV
HHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEE
ICTSAFGMGIDKPDVRWIAHYHPPLSLSAYLQEIGRAGRDNLRSQTLLLTSEPTGWLDPQ
EEECHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCC
DRQMRQYFLKQLRGQQASAQRLVHRLPRQGHIDTITKAFPEADLALALLHQSGHLIWEDP
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCEEEECC
FHFRILAAQGFNPPLIPTKLDITDYLYTRQCRWQFILQQFGFDQEAHHFRCGHCDRCRSR
CEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
TSKSRSFH
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]