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The map label for this gene is yycG [H]

Identifier: 158338249

GI number: 158338249

Start: 5206849

End: 5208849

Strand: Reverse

Name: yycG [H]

Synonym: AM1_5145

Alternate gene names: 158338249

Gene position: 5208849-5206849 (Counterclockwise)

Preceding gene: 158338252

Following gene: 158338248

Centisome position: 80.09

GC content: 51.12

Gene sequence:

>2001_bases
ATGCTCATTGCTACCTCCCTGATACAGGAGCTTCTGGAGACACAGCCCCAGCTTAGACCGCAAATGTATTTTAAGTCTTC
CCTCACGGCTTTATCGCGGGCCATGGAAGATCAAGTACTTGCAGGGACTGATCACCCTTTAGTGATTATTAGCTGTCAAC
GGGAACGCTACTATCGTAAGGCTCTCCACCGCTATGCTCGTCTGGCCGCTCGCTCACCACAAGTCTATATTCTGGCGACC
CCTGAACAAGAGTTTGGGGATGGGGCCGAGCCCTATGAAACGATTGCCTTTGATGCCGCCGATCCCTTGACTCAGGAATG
GCACGTAATTGTTGTAGGCCAACAATATGCGGCTTGCCTTGCCTGTCGTGAACACCCTCAACTCCAGACTTCAGATGCCT
TAAATGCCCCACGGATGGATCAAGCTCGTCGTTACGAAGGCATCTGGACCTTTGATCGGCGGGTGAGTTGTCAAGCGGCC
CATTTGTTCTTGCAGAGAATCAGCCAATATTGTCCCCACCTCACCCCCAAGGTGACTCAGGCCCTCGCTCAGATTGTTCC
TTATGTGGCTTCGACCGTTCGGCAAACGGAGCCAGGTCCGTTTACGGACAGATTGGTCACTTATCTGCAGGCCAGCCAGT
ATCGCCAACAAAAGGCCTACCGACAAATTGCCACTCAAGCCCGTAAAGAACACTTAGTCAACTCCATTACGGCTGCAATC
CGCCGATCCCTGGACCCAGATCATGTGTTAGGGGTCGCGGTACAAGAGCTTGGACAAACCCTGGGTACAGCCCGCTGTTT
AATCTACCGATGTCTGGCCAAGGATAAGGTGACCAAACTGCAATATGAGTTTGTTCAACCCGGGCAGCCTGTCCTGAAAG
GCCAAACCTGGCCCTTGCGGGACAACCCCTGGTTTCAGGACGTGCTCCACACTCAGCAGTGGGTGTATGTCAGTGATGCG
ATGGCTGATGTTCGTTTACAGCAGTCAGCCCTGTTGCAGGATTGGGTAAAGACGGCTCAAATCCAGACCCTCTTGCTGGT
GCCCATGTGGTACCAAGGGCGATTACTGGGGATGGTTGAACTCCACCAGTCGGATTCTCAAAAAGAGATGGCGTGGAAGG
ACGCTGAAATTTCGTTAGTGGATGTGATCGCCTCTCAAATCAGTATTGCTCTTATTCAAGCCCAATCCTTTGCTGACTTA
GGCATTCTGAACCAGCAGTTGGCAGATCTAGAACAAGCTCGAAGTAACTTAATTGCAATCACAGGCCATGAACTGCGGAC
CCCCCTTTCAACCATTCAGATTTGTTTAGAGAGTCTGACCAATGAGCCGGATATGGCACCCGAACTGCAGCAAATTATGT
TGAGCACGGCGCTTTCCGATGCTGAGCGCATGCGCAAGCTCATCCAAGATTTTTTAACTCTATCCCGCTTAGAAAGTGGC
AGAATTGAATGGAATTCTGAACCCTTAGCCCTGCAAGAATGTGTGAATTTAGCCCTTAGTAATATTAGGGCGCAGAGCCA
GCCCCTTCCTAAGATTGAGGCTCATATCCCTGAAAACTTACCCCTGGCCCAAGTCGATGGCGAGTGGCTAGTTGAGGTGT
TGGCCAAATTATTGGACAATGCCTGCAAATTCACCGAGGCTGATGGCCACATCACAATTGATGCGAAAGTCGCCTCTAAA
CAGATGTTAGAAGTGACCGTTGCGGATACAGGTAGGGGTATCGATCCCGATTGTTTAGGTTCAGTCTTTGAGCGGTTTTA
TCAAGAAGAAGGAGCCCTCAGGCGAACCACCGGGGGAACTGGCTTAGGCTTGGCTATCTGTCGTCAAATTATTCATAATC
TGGGGGGAAGAATTTGGGCCTCATCCCAAGGACGGAATCAGGGGACCACGATGCACTTTACGATTCACAGTGTACAGACG
CCTCCCCAGCCTCACACGCCCTCCTCTTCACCTCAGGTTTCTTTACCGAATCATCGGTCTGTAGATTCCTCCTGCCCTTG
A

Upstream 100 bases:

>100_bases
ATAACGATATTTTGCCTTTTTCTAGAGTGCTGTAAGGCTGGGAGAATCGAGTAGGCTGGTTTTGGCGGCACTTACTGTAT
TTCGATCAAAGCCAACGTTG

Downstream 100 bases:

>100_bases
TCCCTGAAGAACTGTAACAGATCCAGCTGAACTTGATTAAAGGGGACGGACGCGATGATAGGATGCCCTCTAGAAGAGAT
TTAGGTACCTCAATCAGTAC

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MLIATSLIQELLETQPQLRPQMYFKSSLTALSRAMEDQVLAGTDHPLVIISCQRERYYRKALHRYARLAARSPQVYILAT
PEQEFGDGAEPYETIAFDAADPLTQEWHVIVVGQQYAACLACREHPQLQTSDALNAPRMDQARRYEGIWTFDRRVSCQAA
HLFLQRISQYCPHLTPKVTQALAQIVPYVASTVRQTEPGPFTDRLVTYLQASQYRQQKAYRQIATQARKEHLVNSITAAI
RRSLDPDHVLGVAVQELGQTLGTARCLIYRCLAKDKVTKLQYEFVQPGQPVLKGQTWPLRDNPWFQDVLHTQQWVYVSDA
MADVRLQQSALLQDWVKTAQIQTLLLVPMWYQGRLLGMVELHQSDSQKEMAWKDAEISLVDVIASQISIALIQAQSFADL
GILNQQLADLEQARSNLIAITGHELRTPLSTIQICLESLTNEPDMAPELQQIMLSTALSDAERMRKLIQDFLTLSRLESG
RIEWNSEPLALQECVNLALSNIRAQSQPLPKIEAHIPENLPLAQVDGEWLVEVLAKLLDNACKFTEADGHITIDAKVASK
QMLEVTVADTGRGIDPDCLGSVFERFYQEEGALRRTTGGTGLGLAICRQIIHNLGGRIWASSQGRNQGTTMHFTIHSVQT
PPQPHTPSSSPQVSLPNHRSVDSSCP

Sequences:

>Translated_666_residues
MLIATSLIQELLETQPQLRPQMYFKSSLTALSRAMEDQVLAGTDHPLVIISCQRERYYRKALHRYARLAARSPQVYILAT
PEQEFGDGAEPYETIAFDAADPLTQEWHVIVVGQQYAACLACREHPQLQTSDALNAPRMDQARRYEGIWTFDRRVSCQAA
HLFLQRISQYCPHLTPKVTQALAQIVPYVASTVRQTEPGPFTDRLVTYLQASQYRQQKAYRQIATQARKEHLVNSITAAI
RRSLDPDHVLGVAVQELGQTLGTARCLIYRCLAKDKVTKLQYEFVQPGQPVLKGQTWPLRDNPWFQDVLHTQQWVYVSDA
MADVRLQQSALLQDWVKTAQIQTLLLVPMWYQGRLLGMVELHQSDSQKEMAWKDAEISLVDVIASQISIALIQAQSFADL
GILNQQLADLEQARSNLIAITGHELRTPLSTIQICLESLTNEPDMAPELQQIMLSTALSDAERMRKLIQDFLTLSRLESG
RIEWNSEPLALQECVNLALSNIRAQSQPLPKIEAHIPENLPLAQVDGEWLVEVLAKLLDNACKFTEADGHITIDAKVASK
QMLEVTVADTGRGIDPDCLGSVFERFYQEEGALRRTTGGTGLGLAICRQIIHNLGGRIWASSQGRNQGTTMHFTIHSVQT
PPQPHTPSSSPQVSLPNHRSVDSSCP
>Mature_666_residues
MLIATSLIQELLETQPQLRPQMYFKSSLTALSRAMEDQVLAGTDHPLVIISCQRERYYRKALHRYARLAARSPQVYILAT
PEQEFGDGAEPYETIAFDAADPLTQEWHVIVVGQQYAACLACREHPQLQTSDALNAPRMDQARRYEGIWTFDRRVSCQAA
HLFLQRISQYCPHLTPKVTQALAQIVPYVASTVRQTEPGPFTDRLVTYLQASQYRQQKAYRQIATQARKEHLVNSITAAI
RRSLDPDHVLGVAVQELGQTLGTARCLIYRCLAKDKVTKLQYEFVQPGQPVLKGQTWPLRDNPWFQDVLHTQQWVYVSDA
MADVRLQQSALLQDWVKTAQIQTLLLVPMWYQGRLLGMVELHQSDSQKEMAWKDAEISLVDVIASQISIALIQAQSFADL
GILNQQLADLEQARSNLIAITGHELRTPLSTIQICLESLTNEPDMAPELQQIMLSTALSDAERMRKLIQDFLTLSRLESG
RIEWNSEPLALQECVNLALSNIRAQSQPLPKIEAHIPENLPLAQVDGEWLVEVLAKLLDNACKFTEADGHITIDAKVASK
QMLEVTVADTGRGIDPDCLGSVFERFYQEEGALRRTTGGTGLGLAICRQIIHNLGGRIWASSQGRNQGTTMHFTIHSVQT
PPQPHTPSSSPQVSLPNHRSVDSSCP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=33.8842975206612, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788393, Length=225, Percent_Identity=30.2222222222222, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=32.7586206896552, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI48994928, Length=228, Percent_Identity=28.5087719298246, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=30.4347826086957, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI87081816, Length=216, Percent_Identity=31.4814814814815, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=30.0847457627119, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=30.9322033898305, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790861, Length=202, Percent_Identity=31.1881188118812, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=27.8260869565217, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=223, Percent_Identity=25.1121076233184, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=26.4957264957265, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788549, Length=209, Percent_Identity=28.2296650717703, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74730; Mature: 74730

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIATSLIQELLETQPQLRPQMYFKSSLTALSRAMEDQVLAGTDHPLVIISCQRERYYRK
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHH
ALHRYARLAARSPQVYILATPEQEFGDGAEPYETIAFDAADPLTQEWHVIVVGQQYAACL
HHHHHHHHHCCCCCEEEEECCCHHHCCCCCCHHHEEECCCCCCCCCCEEEEECCHHHHHH
ACREHPQLQTSDALNAPRMDQARRYEGIWTFDRRVSCQAAHLFLQRISQYCPHLTPKVTQ
HHHCCCCCCCCCCCCCCCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHH
ALAQIVPYVASTVRQTEPGPFTDRLVTYLQASQYRQQKAYRQIATQARKEHLVNSITAAI
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRSLDPDHVLGVAVQELGQTLGTARCLIYRCLAKDKVTKLQYEFVQPGQPVLKGQTWPLR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCC
DNPWFQDVLHTQQWVYVSDAMADVRLQQSALLQDWVKTAQIQTLLLVPMWYQGRLLGMVE
CCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEHHH
LHQSDSQKEMAWKDAEISLVDVIASQISIALIQAQSFADLGILNQQLADLEQARSNLIAI
HHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
TGHELRTPLSTIQICLESLTNEPDMAPELQQIMLSTALSDAERMRKLIQDFLTLSRLESG
ECHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RIEWNSEPLALQECVNLALSNIRAQSQPLPKIEAHIPENLPLAQVDGEWLVEVLAKLLDN
CEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCEEECCHHHHHHHHHHHHHH
ACKFTEADGHITIDAKVASKQMLEVTVADTGRGIDPDCLGSVFERFYQEEGALRRTTGGT
HHCCCCCCCCEEEEEHHCCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCCC
GLGLAICRQIIHNLGGRIWASSQGRNQGTTMHFTIHSVQTPPQPHTPSSSPQVSLPNHRS
CHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEECCCCCC
VDSSCP
CCCCCC
>Mature Secondary Structure
MLIATSLIQELLETQPQLRPQMYFKSSLTALSRAMEDQVLAGTDHPLVIISCQRERYYRK
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHH
ALHRYARLAARSPQVYILATPEQEFGDGAEPYETIAFDAADPLTQEWHVIVVGQQYAACL
HHHHHHHHHCCCCCEEEEECCCHHHCCCCCCHHHEEECCCCCCCCCCEEEEECCHHHHHH
ACREHPQLQTSDALNAPRMDQARRYEGIWTFDRRVSCQAAHLFLQRISQYCPHLTPKVTQ
HHHCCCCCCCCCCCCCCCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHH
ALAQIVPYVASTVRQTEPGPFTDRLVTYLQASQYRQQKAYRQIATQARKEHLVNSITAAI
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRSLDPDHVLGVAVQELGQTLGTARCLIYRCLAKDKVTKLQYEFVQPGQPVLKGQTWPLR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCC
DNPWFQDVLHTQQWVYVSDAMADVRLQQSALLQDWVKTAQIQTLLLVPMWYQGRLLGMVE
CCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEHHH
LHQSDSQKEMAWKDAEISLVDVIASQISIALIQAQSFADLGILNQQLADLEQARSNLIAI
HHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
TGHELRTPLSTIQICLESLTNEPDMAPELQQIMLSTALSDAERMRKLIQDFLTLSRLESG
ECHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RIEWNSEPLALQECVNLALSNIRAQSQPLPKIEAHIPENLPLAQVDGEWLVEVLAKLLDN
CEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCEEECCHHHHHHHHHHHHHH
ACKFTEADGHITIDAKVASKQMLEVTVADTGRGIDPDCLGSVFERFYQEEGALRRTTGGT
HHCCCCCCCCEEEEEHHCCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCCC
GLGLAICRQIIHNLGGRIWASSQGRNQGTTMHFTIHSVQTPPQPHTPSSSPQVSLPNHRS
CHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEECCCCCC
VDSSCP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]