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The map label for this gene is pgm [H]

Identifier: 158338228

GI number: 158338228

Start: 5183228

End: 5184862

Strand: Direct

Name: pgm [H]

Synonym: AM1_5123

Alternate gene names: 158338228

Gene position: 5183228-5184862 (Clockwise)

Preceding gene: 158338227

Following gene: 158338229

Centisome position: 79.7

GC content: 51.19

Gene sequence:

>1635_bases
ATGAGTATCAACACCGTCTATACCCAACCGTTCTCGGACCAAAAACCAGGAACCTCAGGACTGCGTAAGCAGGTAACAGT
TTTTCAACAGTTTCATTATTTAGAGAATTTTATTCAATCCATCTTCGATAGCCTAGACAACTATCAAGGCCAGACCTTAG
TAGTGGGGGGGGATGGTCGCTTCTACAACCGCCATGCCATTCAAGTCATTTTGAAAATGGCGGCGGCCAATGGTTTTGGC
AAGGTATTGGTGGGCCAGAACGGTATTTTATCGACTCCTGCCGTCTCCTGCGTGATTCGTCAGAACAAGGCCTATGGAGG
GATTGTCCTCTCTGCAAGCCACAATCCCGGTGGCCCGGACGGTGACTTTGGCATTAAATACAACATCGGCAATGGTGGTC
CCGCTCCTGAAAAAGTGACCGAAGCCATTTACGCGCGCAGTAAGGAAATCGATGTCTATCGGATCACTGAGGCGGATGAT
GTCAACCTCGATCAATTGGGAACGTCTCAATTGGGAGAGATGACGGTTGAGGTGATTGATTCAGTCCAAGACTATGCCCA
GTTGATGGAGTCCCTGTTTGATTTCGACCGTATTCGACAGCTGCTGACTTCAGGTGGATTTAGCCTGATCGTCGATTCTA
TGCATGCGGTCACGGGTCCCTATGCCCATGCCCTCTTTGCTGATCGTTTAGGGGCGGGGGCAGATAGCGTGATGAATGGT
AAGCCCCTAGAAGATTTTGGTGGCGGTCACCCCGATCCAAATTTGGTCTATGCTCATGAACTAGTGGAGCAACTGTTTGG
GGATAATGCACCTAACTTTGGTGCAGCCTCGGATGGGGATGGCGATCGCAACATGATACTAGGGCAACGCTTTTTTGTGA
CCCCGAGTGATAGTCTGGCCATTCTGACGGCTAACGCGAAGCTTGTACCGGGTTATCAGAATGGTTTAGCGGGCGTGGCC
CGGTCGATGCCCACGAGCCAAGCGGTGGATCGAGTAGCCGCTAAGTTAGGCTTTGACTGCTATGAAACCCCCACGGGCTG
GAAATTCTTTGGCAACCTCTTAGATGCAGATAAAGCAACCCTCTGTGGTGAGGAGAGTTTTGGCACTGGCTCAAACCATG
TGCGGGAGAAGGATGGTCTCTGGGCGGTATTGTTCTGGCTGAATATCCTGGCTGTACGTCAGCAGTCCGTAGAATCCATC
GTTAAAGAGCATTGGCAGGAATATGGCCGCAACTACTATTCCCGCCATGATTATGAAGCCGTTGACTCTGAAAAAGCCAA
TACCCTAATGGCGAATCTGCGAGGTAAGCTCGCGAAGTTGAAGGGTCAAAAGCTGGGGCAATACGAAGTGGACTATGCCG
ATGACTTTAGCTACACGGACCCGGTGGATGGCAGCGTTAGCCAAAAACAGGGGGTCCGCATTGGCTTCACGGATGGCTCT
CGCATCGTCTTTCGACTGTCCGGGACGGGTACCCAAGGAGCTACTCTGCGGGTGTATCTAGAAAGTTATGAACCAGATGT
CAGTAAACAGGGCCTCGATCCGCAAGATGCTCTAGCACCGCTAATTACTTTGGCAGATGAAGTGGCTCAAATTCGCACAC
TGACGGGCCGTGACGAACCCACGGTGATCACCTAA

Upstream 100 bases:

>100_bases
ACCTAGTCCGGGGTATCCTAATCAACGGTTACTTCTATATTTCAGTGGCTATCAACTAGCGCTATCTAGATTTCATTCAC
TCTCATTAGTGCCAATATTC

Downstream 100 bases:

>100_bases
ATACCTCCATCGCTCCAATGACAATTAGTGGCATTGGAACGATTTGCCCACTCAAGGTTCTGCCGCATTTCCTGCCCCAT
GGCCTGAACACTGGGATCAG

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MSINTVYTQPFSDQKPGTSGLRKQVTVFQQFHYLENFIQSIFDSLDNYQGQTLVVGGDGRFYNRHAIQVILKMAAANGFG
KVLVGQNGILSTPAVSCVIRQNKAYGGIVLSASHNPGGPDGDFGIKYNIGNGGPAPEKVTEAIYARSKEIDVYRITEADD
VNLDQLGTSQLGEMTVEVIDSVQDYAQLMESLFDFDRIRQLLTSGGFSLIVDSMHAVTGPYAHALFADRLGAGADSVMNG
KPLEDFGGGHPDPNLVYAHELVEQLFGDNAPNFGAASDGDGDRNMILGQRFFVTPSDSLAILTANAKLVPGYQNGLAGVA
RSMPTSQAVDRVAAKLGFDCYETPTGWKFFGNLLDADKATLCGEESFGTGSNHVREKDGLWAVLFWLNILAVRQQSVESI
VKEHWQEYGRNYYSRHDYEAVDSEKANTLMANLRGKLAKLKGQKLGQYEVDYADDFSYTDPVDGSVSQKQGVRIGFTDGS
RIVFRLSGTGTQGATLRVYLESYEPDVSKQGLDPQDALAPLITLADEVAQIRTLTGRDEPTVIT

Sequences:

>Translated_544_residues
MSINTVYTQPFSDQKPGTSGLRKQVTVFQQFHYLENFIQSIFDSLDNYQGQTLVVGGDGRFYNRHAIQVILKMAAANGFG
KVLVGQNGILSTPAVSCVIRQNKAYGGIVLSASHNPGGPDGDFGIKYNIGNGGPAPEKVTEAIYARSKEIDVYRITEADD
VNLDQLGTSQLGEMTVEVIDSVQDYAQLMESLFDFDRIRQLLTSGGFSLIVDSMHAVTGPYAHALFADRLGAGADSVMNG
KPLEDFGGGHPDPNLVYAHELVEQLFGDNAPNFGAASDGDGDRNMILGQRFFVTPSDSLAILTANAKLVPGYQNGLAGVA
RSMPTSQAVDRVAAKLGFDCYETPTGWKFFGNLLDADKATLCGEESFGTGSNHVREKDGLWAVLFWLNILAVRQQSVESI
VKEHWQEYGRNYYSRHDYEAVDSEKANTLMANLRGKLAKLKGQKLGQYEVDYADDFSYTDPVDGSVSQKQGVRIGFTDGS
RIVFRLSGTGTQGATLRVYLESYEPDVSKQGLDPQDALAPLITLADEVAQIRTLTGRDEPTVIT
>Mature_543_residues
SINTVYTQPFSDQKPGTSGLRKQVTVFQQFHYLENFIQSIFDSLDNYQGQTLVVGGDGRFYNRHAIQVILKMAAANGFGK
VLVGQNGILSTPAVSCVIRQNKAYGGIVLSASHNPGGPDGDFGIKYNIGNGGPAPEKVTEAIYARSKEIDVYRITEADDV
NLDQLGTSQLGEMTVEVIDSVQDYAQLMESLFDFDRIRQLLTSGGFSLIVDSMHAVTGPYAHALFADRLGAGADSVMNGK
PLEDFGGGHPDPNLVYAHELVEQLFGDNAPNFGAASDGDGDRNMILGQRFFVTPSDSLAILTANAKLVPGYQNGLAGVAR
SMPTSQAVDRVAAKLGFDCYETPTGWKFFGNLLDADKATLCGEESFGTGSNHVREKDGLWAVLFWLNILAVRQQSVESIV
KEHWQEYGRNYYSRHDYEAVDSEKANTLMANLRGKLAKLKGQKLGQYEVDYADDFSYTDPVDGSVSQKQGVRIGFTDGSR
IVFRLSGTGTQGATLRVYLESYEPDVSKQGLDPQDALAPLITLADEVAQIRTLTGRDEPTVIT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=562, Percent_Identity=57.1174377224199, Blast_Score=643, Evalue=0.0,
Organism=Homo sapiens, GI290463102, Length=562, Percent_Identity=56.7615658362989, Blast_Score=640, Evalue=0.0,
Organism=Homo sapiens, GI133922562, Length=563, Percent_Identity=51.1545293072824, Blast_Score=569, Evalue=1e-162,
Organism=Homo sapiens, GI290463104, Length=366, Percent_Identity=56.5573770491803, Blast_Score=424, Evalue=1e-118,
Organism=Homo sapiens, GI239741729, Length=135, Percent_Identity=52.5925925925926, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI239743670, Length=135, Percent_Identity=51.1111111111111, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1786904, Length=425, Percent_Identity=26.8235294117647, Blast_Score=86, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17535441, Length=560, Percent_Identity=52.8571428571429, Blast_Score=574, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6323752, Length=568, Percent_Identity=47.7112676056338, Blast_Score=516, Evalue=1e-147,
Organism=Saccharomyces cerevisiae, GI6322722, Length=570, Percent_Identity=47.8947368421053, Blast_Score=508, Evalue=1e-144,
Organism=Drosophila melanogaster, GI17864244, Length=564, Percent_Identity=51.4184397163121, Blast_Score=570, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59216; Mature: 59085

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINTVYTQPFSDQKPGTSGLRKQVTVFQQFHYLENFIQSIFDSLDNYQGQTLVVGGDGR
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
FYNRHAIQVILKMAAANGFGKVLVGQNGILSTPAVSCVIRQNKAYGGIVLSASHNPGGPD
EEHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHEEEEECCCCCCCEEEECCCCCCCCC
GDFGIKYNIGNGGPAPEKVTEAIYARSKEIDVYRITEADDVNLDQLGTSQLGEMTVEVID
CCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHCCCHHHHHHHHHHHH
SVQDYAQLMESLFDFDRIRQLLTSGGFSLIVDSMHAVTGPYAHALFADRLGAGADSVMNG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHCCC
KPLEDFGGGHPDPNLVYAHELVEQLFGDNAPNFGAASDGDGDRNMILGQRFFVTPSDSLA
CCCHHHCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCEEEECCCCCEE
ILTANAKLVPGYQNGLAGVARSMPTSQAVDRVAAKLGFDCYETPTGWKFFGNLLDADKAT
EEEECCEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHH
LCGEESFGTGSNHVREKDGLWAVLFWLNILAVRQQSVESIVKEHWQEYGRNYYSRHDYEA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VDSEKANTLMANLRGKLAKLKGQKLGQYEVDYADDFSYTDPVDGSVSQKQGVRIGFTDGS
HCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCHHHCCCEEEECCCC
RIVFRLSGTGTQGATLRVYLESYEPDVSKQGLDPQDALAPLITLADEVAQIRTLTGRDEP
EEEEEEECCCCCCCEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
TVIT
CEEC
>Mature Secondary Structure 
SINTVYTQPFSDQKPGTSGLRKQVTVFQQFHYLENFIQSIFDSLDNYQGQTLVVGGDGR
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
FYNRHAIQVILKMAAANGFGKVLVGQNGILSTPAVSCVIRQNKAYGGIVLSASHNPGGPD
EEHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHEEEEECCCCCCCEEEECCCCCCCCC
GDFGIKYNIGNGGPAPEKVTEAIYARSKEIDVYRITEADDVNLDQLGTSQLGEMTVEVID
CCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHCCCHHHHHHHHHHHH
SVQDYAQLMESLFDFDRIRQLLTSGGFSLIVDSMHAVTGPYAHALFADRLGAGADSVMNG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHCCC
KPLEDFGGGHPDPNLVYAHELVEQLFGDNAPNFGAASDGDGDRNMILGQRFFVTPSDSLA
CCCHHHCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCEEEECCCCCEE
ILTANAKLVPGYQNGLAGVARSMPTSQAVDRVAAKLGFDCYETPTGWKFFGNLLDADKAT
EEEECCEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHH
LCGEESFGTGSNHVREKDGLWAVLFWLNILAVRQQSVESIVKEHWQEYGRNYYSRHDYEA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VDSEKANTLMANLRGKLAKLKGQKLGQYEVDYADDFSYTDPVDGSVSQKQGVRIGFTDGS
HCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCHHHCCCEEEECCCC
RIVFRLSGTGTQGATLRVYLESYEPDVSKQGLDPQDALAPLITLADEVAQIRTLTGRDEP
EEEEEEECCCCCCCEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
TVIT
CEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]