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The map label for this gene is yciR [C]

Identifier: 158338223

GI number: 158338223

Start: 5177282

End: 5179045

Strand: Reverse

Name: yciR [C]

Synonym: AM1_5118

Alternate gene names: 158338223

Gene position: 5179045-5177282 (Counterclockwise)

Preceding gene: 158338226

Following gene: 158338218

Centisome position: 79.63

GC content: 47.73

Gene sequence:

>1764_bases
ATGATGCTGGCCTTTACGGTTGCTGTCTGGCCTCAAGTCAACTCAAATCTATTCATCGTTTGGATGAGTGGCTATGCAAT
CTGGATCGGCATCACCTTTTTGGCCCATTCCGGTCGGATTCTGGGGAAATGGCGAGATCGCTACGAAACTCCAATTTTAG
TCAATATGATTAGCGCCAGTCGAGGCATTTGGATCTGTGGAATTGCCTTAACCAATTGGCCAGCCTTTATTCAAGGCGGA
GAGTTTTTTTGGACATTGACGACCTTATGGGCCATTGCCTTAGCAGCCCAGACCATTATGGTGACCGTTGGCAATGACTA
TTTTATTCAAGCAATTCTGGCAACGGCGATTGTGATGATGGCTGCCACGCGTCAATGGCAAATTAGCATCGGTACCATTT
TCTTCCTGATCCCGGCGATTAAAGCATTAGATTCAGCTCGACAAGTTCGGATGAATGAGGTGAAGTTACGCACCACTCTC
ACCTACCAAGCTCGCTACGATGGCCTCACGGGATTGCTCAATCGTGTGGGGATTGAGGAACAGTTCTCTGAGCTTCCTCC
TGGACCTTTAGCAGCGATGTTTGTGGATCTCGATCGATTTAAGGAGGTCAATGATCGCCTGGGTCATACGATGGGGGACG
AGCTGCTCGAACAAGTGGGTCAACGGGTTCAAGATGTTATCCAGCATCGGTCCCATTTATTGGCTCGGTTGGGGGGAGAT
GAATTTTTTCTAGTATTGCCGGGATGTCCGTTGCGAGACTTACTTGCGATCTCAGACACGATCCTCAACACCCTAGAACA
ACCCTTTACATTAACCTCAGGCCAAGCCTATATTTCAGCCAGCATTGGTACTGCTACAACCAGCGGAGATATCGCCAATC
TAGAACAGCTGATCAGAGATGCGGATCAGGCCATGTATCGCGCTAAAGAAGCGGGGCGGCGGCGGGTCATTTACTATGAC
CAATCGTTACGCCAAGATGCTCAAGAACGCCTGGGGCTAGAAAGCAGCCTCAGACAGGCCGTTGCAGAAAATAAGATCGT
AGCTTGGGGACAACCGATCATTAACTATCAAACGGGCACCATCGCCAAGGTTGAGCTATTGGCCCGCTGGAAGCTAGATC
AAAAAAATATTCCTCCTGATTTGTTTATTAGCATTGCAGCCAATATTGGTCTCACTAGCGATATTGCCCGGTTCATGGTT
AACCAAGCCCAGAAATCTCTAGAAAAGTGGAAAAAGATTCCAGCGCTCAAAGAGACCTGCATTACGGTCAATGTCGAAGC
ACAGGATTTAGTAGAAGGTCTGGTTGTTGATTATCTGGAGAACCTCGTTTTTACAGAACAAATTGATCCAGCCAAACTGA
TTCTAGAAATTACTGAGAGGGGGCTGATTGAAGCTGAATCGAAAGCCAGGTTTCAAATTGATCGGTTGCATACCCTGGGG
GTTCGGGTCGCCATTGATGATTTTGGGGCGGGGTATTCCTCTTTGCGTTCCGTCATGACGCTTCCAGTCGATCTCCTCAA
GTTTGATCGTTCTCTAGTCGCGGGTGCAACTCAAGACCAGCGCATGCAAAATGTACTGTCCGCCATGGTGGAAATGGCCA
GTAGTTTCAAGATTACGGTGATTGGTGAAGGGATTGAGAAGCCTGAGGATATCGAAGTTATGAAACAACTCAAGGTTCAC
CTCTTACAAGGTTTTTACTGTGCTAACCCCATGCCGCTAAAAGAGGTTTCCAACTTTGCCAAAGAGTTTTTACCCCATGA
TTGA

Upstream 100 bases:

>100_bases
CAATCAGCCACATCTTCAGACGATTCAAACCGCTCTCCAACGGGATGTGGATCGGAGGTTGGTGAGTGAACGATGGCGCA
TTGTTCAAGGCTCATTTGCA

Downstream 100 bases:

>100_bases
TGGTTGGTTAGAAACTCAAGATGTGGCAATAGAGCGAAGCTCAAAAAGCGTCCACAAGGTTTAACCGCAGTACTCAGCCC
TATCTCCAAATAGTAGATAG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 587

Protein sequence:

>587_residues
MMLAFTVAVWPQVNSNLFIVWMSGYAIWIGITFLAHSGRILGKWRDRYETPILVNMISASRGIWICGIALTNWPAFIQGG
EFFWTLTTLWAIALAAQTIMVTVGNDYFIQAILATAIVMMAATRQWQISIGTIFFLIPAIKALDSARQVRMNEVKLRTTL
TYQARYDGLTGLLNRVGIEEQFSELPPGPLAAMFVDLDRFKEVNDRLGHTMGDELLEQVGQRVQDVIQHRSHLLARLGGD
EFFLVLPGCPLRDLLAISDTILNTLEQPFTLTSGQAYISASIGTATTSGDIANLEQLIRDADQAMYRAKEAGRRRVIYYD
QSLRQDAQERLGLESSLRQAVAENKIVAWGQPIINYQTGTIAKVELLARWKLDQKNIPPDLFISIAANIGLTSDIARFMV
NQAQKSLEKWKKIPALKETCITVNVEAQDLVEGLVVDYLENLVFTEQIDPAKLILEITERGLIEAESKARFQIDRLHTLG
VRVAIDDFGAGYSSLRSVMTLPVDLLKFDRSLVAGATQDQRMQNVLSAMVEMASSFKITVIGEGIEKPEDIEVMKQLKVH
LLQGFYCANPMPLKEVSNFAKEFLPHD

Sequences:

>Translated_587_residues
MMLAFTVAVWPQVNSNLFIVWMSGYAIWIGITFLAHSGRILGKWRDRYETPILVNMISASRGIWICGIALTNWPAFIQGG
EFFWTLTTLWAIALAAQTIMVTVGNDYFIQAILATAIVMMAATRQWQISIGTIFFLIPAIKALDSARQVRMNEVKLRTTL
TYQARYDGLTGLLNRVGIEEQFSELPPGPLAAMFVDLDRFKEVNDRLGHTMGDELLEQVGQRVQDVIQHRSHLLARLGGD
EFFLVLPGCPLRDLLAISDTILNTLEQPFTLTSGQAYISASIGTATTSGDIANLEQLIRDADQAMYRAKEAGRRRVIYYD
QSLRQDAQERLGLESSLRQAVAENKIVAWGQPIINYQTGTIAKVELLARWKLDQKNIPPDLFISIAANIGLTSDIARFMV
NQAQKSLEKWKKIPALKETCITVNVEAQDLVEGLVVDYLENLVFTEQIDPAKLILEITERGLIEAESKARFQIDRLHTLG
VRVAIDDFGAGYSSLRSVMTLPVDLLKFDRSLVAGATQDQRMQNVLSAMVEMASSFKITVIGEGIEKPEDIEVMKQLKVH
LLQGFYCANPMPLKEVSNFAKEFLPHD
>Mature_587_residues
MMLAFTVAVWPQVNSNLFIVWMSGYAIWIGITFLAHSGRILGKWRDRYETPILVNMISASRGIWICGIALTNWPAFIQGG
EFFWTLTTLWAIALAAQTIMVTVGNDYFIQAILATAIVMMAATRQWQISIGTIFFLIPAIKALDSARQVRMNEVKLRTTL
TYQARYDGLTGLLNRVGIEEQFSELPPGPLAAMFVDLDRFKEVNDRLGHTMGDELLEQVGQRVQDVIQHRSHLLARLGGD
EFFLVLPGCPLRDLLAISDTILNTLEQPFTLTSGQAYISASIGTATTSGDIANLEQLIRDADQAMYRAKEAGRRRVIYYD
QSLRQDAQERLGLESSLRQAVAENKIVAWGQPIINYQTGTIAKVELLARWKLDQKNIPPDLFISIAANIGLTSDIARFMV
NQAQKSLEKWKKIPALKETCITVNVEAQDLVEGLVVDYLENLVFTEQIDPAKLILEITERGLIEAESKARFQIDRLHTLG
VRVAIDDFGAGYSSLRSVMTLPVDLLKFDRSLVAGATQDQRMQNVLSAMVEMASSFKITVIGEGIEKPEDIEVMKQLKVH
LLQGFYCANPMPLKEVSNFAKEFLPHD

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=438, Percent_Identity=31.0502283105023, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87081921, Length=442, Percent_Identity=26.6968325791855, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI226510982, Length=401, Percent_Identity=27.431421446384, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1786507, Length=234, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081743, Length=249, Percent_Identity=29.718875502008, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI87081845, Length=240, Percent_Identity=30, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87081980, Length=248, Percent_Identity=29.4354838709677, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1790496, Length=246, Percent_Identity=26.8292682926829, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788381, Length=437, Percent_Identity=24.9427917620137, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1788849, Length=275, Percent_Identity=27.6363636363636, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI87082096, Length=424, Percent_Identity=25.7075471698113, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788502, Length=277, Percent_Identity=27.7978339350181, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081881, Length=173, Percent_Identity=34.1040462427746, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082007, Length=192, Percent_Identity=34.8958333333333, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI145693134, Length=165, Percent_Identity=36.3636363636364, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787802, Length=237, Percent_Identity=29.535864978903, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787055, Length=259, Percent_Identity=24.3243243243243, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787056, Length=176, Percent_Identity=30.1136363636364, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786584, Length=205, Percent_Identity=28.780487804878, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081977, Length=237, Percent_Identity=26.5822784810127, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787262, Length=170, Percent_Identity=32.3529411764706, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789650, Length=472, Percent_Identity=21.8220338983051, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788956, Length=171, Percent_Identity=32.7485380116959, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787816, Length=167, Percent_Identity=28.7425149700599, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 65732; Mature: 65732

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLAFTVAVWPQVNSNLFIVWMSGYAIWIGITFLAHSGRILGKWRDRYETPILVNMISAS
CEEEEEEEECCCCCCCEEEEEECCEEEEHHHHHHHCCCCEEHHHHHCCCCCCEEEEHHCC
RGIWICGIALTNWPAFIQGGEFFWTLTTLWAIALAAQTIMVTVGNDYFIQAILATAIVMM
CCEEEEEEECCCCCHHEECCCHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHH
AATRQWQISIGTIFFLIPAIKALDSARQVRMNEVKLRTTLTYQARYDGLTGLLNRVGIEE
HHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEHHHCCHHHHHHHCCCHH
QFSELPPGPLAAMFVDLDRFKEVNDRLGHTMGDELLEQVGQRVQDVIQHRSHLLARLGGD
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EFFLVLPGCPLRDLLAISDTILNTLEQPFTLTSGQAYISASIGTATTSGDIANLEQLIRD
EEEEEECCCCHHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCCCCHHHHHHHHHH
ADQAMYRAKEAGRRRVIYYDQSLRQDAQERLGLESSLRQAVAENKIVAWGQPIINYQTGT
HHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCEEEECCCC
IAKVELLARWKLDQKNIPPDLFISIAANIGLTSDIARFMVNQAQKSLEKWKKIPALKETC
CHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCE
ITVNVEAQDLVEGLVVDYLENLVFTEQIDPAKLILEITERGLIEAESKARFQIDRLHTLG
EEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHCE
VRVAIDDFGAGYSSLRSVMTLPVDLLKFDRSLVAGATQDQRMQNVLSAMVEMASSFKITV
EEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEE
IGEGIEKPEDIEVMKQLKVHLLQGFYCANPMPLKEVSNFAKEFLPHD
EECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMLAFTVAVWPQVNSNLFIVWMSGYAIWIGITFLAHSGRILGKWRDRYETPILVNMISAS
CEEEEEEEECCCCCCCEEEEEECCEEEEHHHHHHHCCCCEEHHHHHCCCCCCEEEEHHCC
RGIWICGIALTNWPAFIQGGEFFWTLTTLWAIALAAQTIMVTVGNDYFIQAILATAIVMM
CCEEEEEEECCCCCHHEECCCHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHH
AATRQWQISIGTIFFLIPAIKALDSARQVRMNEVKLRTTLTYQARYDGLTGLLNRVGIEE
HHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEHHHCCHHHHHHHCCCHH
QFSELPPGPLAAMFVDLDRFKEVNDRLGHTMGDELLEQVGQRVQDVIQHRSHLLARLGGD
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EFFLVLPGCPLRDLLAISDTILNTLEQPFTLTSGQAYISASIGTATTSGDIANLEQLIRD
EEEEEECCCCHHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCCCCHHHHHHHHHH
ADQAMYRAKEAGRRRVIYYDQSLRQDAQERLGLESSLRQAVAENKIVAWGQPIINYQTGT
HHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCEEEECCCC
IAKVELLARWKLDQKNIPPDLFISIAANIGLTSDIARFMVNQAQKSLEKWKKIPALKETC
CHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCE
ITVNVEAQDLVEGLVVDYLENLVFTEQIDPAKLILEITERGLIEAESKARFQIDRLHTLG
EEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHCE
VRVAIDDFGAGYSSLRSVMTLPVDLLKFDRSLVAGATQDQRMQNVLSAMVEMASSFKITV
EEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEE
IGEGIEKPEDIEVMKQLKVHLLQGFYCANPMPLKEVSNFAKEFLPHD
EECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]