Click here to switch to the map view.

The map label for this gene is cya [H]

Identifier: 158338171

GI number: 158338171

Start: 5108795

End: 5113414

Strand: Reverse

Name: cya [H]

Synonym: AM1_5063

Alternate gene names: 158338171

Gene position: 5113414-5108795 (Counterclockwise)

Preceding gene: 158338173

Following gene: 158338170

Centisome position: 78.62

GC content: 53.57

Gene sequence:

>4620_bases
ATGACAAATGCTCGATTTAATAGGTTTGGCTTCCATCTGTTTGGTCCAGCGAGATTAGGGAATAGTATTACCCTTGGTAA
TGATGGCCGCGCCTATATCCGCAAGAATCTAATCGCACCCGTCGGTGCTCCCGCCGTTGACATTACAGGGAACCATGCGT
CCTTGTTTATCTCCCGTCGCGGATCTCTTTCAGCTCCCGATTCGGGTAATACAGCCGTCCTGGTCAGTGGTGCCAATGCC
CGGATTACAAACTTCGGGTCCATCGCGGGTCATTTCAACGGCATCAGCTCTACAGGTGGTGGTCTCAGACTAACGAATAT
TGGGACCATCAGCTCTAATAGCCGTGCTATCGATCTTAGTGATGGCGACGGTATTCGCGTCACCAACTTCGGTCGAATTT
TGGGGACTGGCAATCAGCGTAACGGGACGCTGTATGTGGATGGCACAGTTGATGACCTCAGGATATTTAACGGTCATCGC
GGTGTGATTGATGCTGGTGTTGGCAATCTCGGCGATGCTGTTTCCGTACAGGTGGGTGCTGCAGGCGATCCCAGTAATGA
AGACATTAATATCGTTAACTTTGGGCGCTTACAGGGCCGAGGGGATGGGGATGAAGTCTTCGCAGATGGCACCCGGGTGA
CCGGAAATGGCTCCAGTGGTCTGCGATTTTTCAACGGCTCTGGGCTTTCAGAGGCAACGATCAGCGGCTCGGTCAGGAAC
AGTGGCACGATTACAGCAGAGGTGAACGTTGGTTTCCTTGGCGGCGTCGTGGTGGAAGACGGTGTGGCCTTTGACGGTCG
CATTATCAATGGCTTCAGAGGGTTGATTAGCGGTCCCCGTAACGGACTCTACATTGGCAATGCTGAGCACGATCTGGAGA
TTTTCAACCATGGACGCATTAAGTCCGGCAGCCGCACCGTTAATTTGGACGGTGATAATGTCACATTCATTAATGCTGGC
GATGTAGTCGGTACTGGGGATCAGCGTAACGGCACCCTATATCTCGATGGAACAGCAGACGACATTAGTGTCAGGAATTG
GCGACGGGGCGTTATCGACGCGGGATCTGGTAACTCGGGTAGCGGTATCTCTATTCAAGTGGGCGGCTCTTCTGAAAATG
GCTTAAGCGAAGGCATCAGTATTGATAACAGCGGTCTGATTCGAGGACGTGGCAGCGACAACGTTCCGGCAGGAGTACGT
CTATTCGTAGGCTCTGGCTTAGACACCGCGACCTTCTCAGGGACGATTGCGAATAATAGAGGTGGCGTCATTGCATCTGA
AACAGATGCGGGCCTCTTGATTGAATCGGGGGTTGTCTTTGATGGTCAGATTACTAATCGCGGCGTAATCGCAGGCGGTA
ATGGCTTTGCGATTGATGCCAATGGTGCTTTGGGCAGTGTTGAAGTAACGAATCATGGCACGCTCGACGGTGAGGTCCGC
CTCGGGGCTGGCAGCGATCGCTTTACTCAATCGGGTCGGGCGGGTGTTACCGTCACTGGTGGTCTTGGCGATGACACGAT
TGTCGGTGGCAGAGGGACAGATACGGTTCGCTATGACGACAGCGATGTGGGCGTTACCGTTGACTTGGGTGCAGGGACTG
CTGAGCGAGAGACAGGGTTTAACGTCACGATCGCAGATTTAGCACTTGTCAATCCCAACGATGGTATTGATCCATCCACC
ATTGTTGAAGAAGGGATTGCCGGAAATCTGTACTTCAACTTCCATACCACTGACTTCCCCTCCGGTGAACTGCGTGGCCA
GCTTGAATTGGTTGCTGATAACCGGGATGGTAACGGCGTCGGCACGGTTGAGTTCGCCGCCAACCTCAGCGGTGACCAAG
AAGTGCCTCCCGTTGAGACGGATGCTTCAGGCATTGCCACCACCACCTTTACCGTGGGGCCAGACGGATCGGTCGCTTAC
AGCACGGTCGCCTCGCTGTCGGGTATCACCCAAGCCGATCTGCTCCCCGTCAACATCGGTAACGGCACACTCAGCCCCAT
CCACCTTCATAACGCACCAACAGGCATCAACGGTCCCGTAGTTGTCGATATCGCCAGCGATGCAGGACCAGATGGAATTG
GTGCCGATGGCTTTAATCTCACCGTGCCGGAACTGGCCCTGGTTGACCCCAATGCTGGGATTGGCGCTGACCAAATCATT
GCTGAGGGCGTTGCCGGTAACCTTTACTTCAATTTCCACACCAACGACTTCCCATCCGGTGAAGTGCGTGGTCAGCTTGA
GTTGATTGCCGACAATCGTGATGCAGACGGCATCGGTACTGTTGAGTTCGCGACAGACCTTAGTGGTGATCAAGAAGTGC
CTCCGGTTGGCACTGATTCATCAGGGACGGCGACTGCCCTGTTTACAGTTGCACCGGATGGATCCGTTACCTATAGCACC
AGTGCTTCCTTAGTTGGCATCAACCCCGAAGATCTGTTGCCAGTAAATATCGGTAATGGAACGCTCAGCCCCATCCATTT
GCACAACGCACCTGCGGGTATCAACGGCCCGGTCGTTATTAATATCGCCACCGATGCCGGTCCAACAGGACTCGTCCCCA
TTGCTGAGACCGATACACTCACCAACATTGAGAATGTGATTGGATCAAACGATGCCGATCTATTAATCGGAGATGGTGAA
AGCAATACGCTGCAAGGTTTAGATGGTGACGATGCGCTGCAGGGCGGCGGCGGCAATGACACCCTCGAAGGCGGTGCAGG
TGACGACACGCTCCAGGGGGGCGGCGGTAACGATAGCCTCGACGGTGGCGAAGGAACAGATATTGCTAGCTTTGCCGATA
TCGGCGCGGACGTTAACGTCACGCTCAATGCTGATGGTACGGGATCAGCAGAATATGAAGTCAATGGCCGCACGGTCACC
GATACATTCACCAGTATTGAGGGCGTGATTGGTTCTGCTAACAACGACACCATCATTGCCAATGGTGCAGCAGGTAACAT
CATTGAGGGTGGCGCAGGGGATGACTTTATTGCGGGCGCAGGCGGTACCGACACGCTTGATGGCGGAGAGGGGAACGACA
CCAATTCCTTTATCAATATCGGTGCTCCGGTCGTGGCTAGCTTGGCCAGTGGCAGCGCATCTTACGAAGTAGGGTCCGGC
ACCGTCTTCGAGAACTTCTCTAACTTTGAGAATCTGGACGGTTCTGCCCAAAACGATCAGCTCTTTGGCGACGGAAACGA
CAATACCCTTGCTGGTAACGACGGCGATGATCTCCTCTCTGGTGGCGGCGGTGACGATACGCTGCTGGGGGGACTCGGTG
ACGATACGCTCCAAGGTGGCGGCGGTAACGACCTCACGGATGGCGGTGACGGCATCGACACGGCTGACTTCCAAAATATT
GGTGCTGATGTGACTGCTGATCTGTCTACAGGACAGGCTCAGTACATCGCCAACGGTAACCCAATTCAAGATCAGCTCAG
CAATATTGAGAATCTGACGGGTTCCACCAATAACGATGCTCTCACTGGCGATGATGGCGACAATGTATTGGCGGGTAATG
CAGGGAACGATACCCTCCAGGGCGGTGCAGGCAACGATCTGCTACGCGGCGACGAGATCGGTTCTGGCACAGCGATTCGC
GTCACTGTCACCAACACGCTGGGTGAAGGTGGCACCTTCTTAACCCCCATTTGGTTCGGTTTTCATGATGGTGCCAACTT
CGATCTGTTTACAGCGGGTGAAGCGGCCAGTCTTGGTCTAGAAAGACTGGCAGAGGATGGTTCTATTGAAGGGATTGCCG
CTGAGTTCAATGCTCAAACGGGTGCCAATGGCGTTGATGGCACCATCATCGGTGGTGCAGGTATACCCGGCCCCATTGAT
CCGGGTGAAAGTGCCTCTTTGACGCTAAATGTCAACGCCAATCAAGTTGGGCTAGGGTTCTTTACCTGGGGCACAATGAT
TATTCCGTCTAATGATGCCTTCCTATCGGTACCCGATAATCCCTTGGCCGATCCGATCTTCGATGCAGCAGGAAACTTTA
TTGGTCCGGTTGTCATTGAACGCCGCGGTAGCGATGTGCTTGATGCTGGAACTGAAGTGAATAATGAGCTAGATGCAGCC
TTCCTCAACCAAACGGCCCGCGATACCGGGCTGGATGAGAATGGTGTTGTCGGTGCTCATCCTGGCTTCAATGGTTCAGT
GGGCAATCCTGATGCTACGCCCGTCAATATCTTGGGAGGAACCACTGCCCCAGGTGCCGTCATCGATCCAGTGGTGGGCG
ACTTCACGGCGGATGATGATCTACTGCTGCGGATCAACATTGAGCGGGTGGCGATCGCAGATGCAGGCGACGATTTACTC
GAAGGTGGAGAAGGCAACGATACCCTTGAAGGGGGCGGTGGTAATGACACATTGACGGGTGGCGCTGGTAATGACGTGTT
TGTGTTTGAAGCAGATAGCGGTGCCAATATCGTAACTGACTTTGATATTGCTGATGACGTCCTTGATGTCAGTGCCATCT
TCAGCGATCTTGACGCCACTTTAGGCGCTGCCAGTCAAAAAGGGAATGACGTCGCGATCGACTTTGGTGACAATCACTCT
GTTCTATTACTCAATATTGATCTGACAACACTCAGGGATGACAATTTCATCTTTGAGTAG

Upstream 100 bases:

>100_bases
AGTATCGTCGTCTCAACCCAGCGCCTGCTGCAGCCTGCATGATATGAGGTCTCCGCTGTTGCAAACCTTCAACAGGCGGT
TAATTGGGAATAGTAACGCC

Downstream 100 bases:

>100_bases
GTGATTCATCAAATGCCTAATCTGAGTTCGGGGTATGTCCGTTTCTAAGATCCTTCTACGGAAGAAGGTAGGGTTTACCC
TACGCAAGAATCGGGGAGTT

Product: hemolysin-type calcium-binding protein

Products: NA

Alternate protein names: AC-HLY; ACT; Cyclolysin; ATP pyrophosphate-lyase; Adenylyl cyclase [H]

Number of amino acids: Translated: 1539; Mature: 1538

Protein sequence:

>1539_residues
MTNARFNRFGFHLFGPARLGNSITLGNDGRAYIRKNLIAPVGAPAVDITGNHASLFISRRGSLSAPDSGNTAVLVSGANA
RITNFGSIAGHFNGISSTGGGLRLTNIGTISSNSRAIDLSDGDGIRVTNFGRILGTGNQRNGTLYVDGTVDDLRIFNGHR
GVIDAGVGNLGDAVSVQVGAAGDPSNEDINIVNFGRLQGRGDGDEVFADGTRVTGNGSSGLRFFNGSGLSEATISGSVRN
SGTITAEVNVGFLGGVVVEDGVAFDGRIINGFRGLISGPRNGLYIGNAEHDLEIFNHGRIKSGSRTVNLDGDNVTFINAG
DVVGTGDQRNGTLYLDGTADDISVRNWRRGVIDAGSGNSGSGISIQVGGSSENGLSEGISIDNSGLIRGRGSDNVPAGVR
LFVGSGLDTATFSGTIANNRGGVIASETDAGLLIESGVVFDGQITNRGVIAGGNGFAIDANGALGSVEVTNHGTLDGEVR
LGAGSDRFTQSGRAGVTVTGGLGDDTIVGGRGTDTVRYDDSDVGVTVDLGAGTAERETGFNVTIADLALVNPNDGIDPST
IVEEGIAGNLYFNFHTTDFPSGELRGQLELVADNRDGNGVGTVEFAANLSGDQEVPPVETDASGIATTTFTVGPDGSVAY
STVASLSGITQADLLPVNIGNGTLSPIHLHNAPTGINGPVVVDIASDAGPDGIGADGFNLTVPELALVDPNAGIGADQII
AEGVAGNLYFNFHTNDFPSGEVRGQLELIADNRDADGIGTVEFATDLSGDQEVPPVGTDSSGTATALFTVAPDGSVTYST
SASLVGINPEDLLPVNIGNGTLSPIHLHNAPAGINGPVVINIATDAGPTGLVPIAETDTLTNIENVIGSNDADLLIGDGE
SNTLQGLDGDDALQGGGGNDTLEGGAGDDTLQGGGGNDSLDGGEGTDIASFADIGADVNVTLNADGTGSAEYEVNGRTVT
DTFTSIEGVIGSANNDTIIANGAAGNIIEGGAGDDFIAGAGGTDTLDGGEGNDTNSFINIGAPVVASLASGSASYEVGSG
TVFENFSNFENLDGSAQNDQLFGDGNDNTLAGNDGDDLLSGGGGDDTLLGGLGDDTLQGGGGNDLTDGGDGIDTADFQNI
GADVTADLSTGQAQYIANGNPIQDQLSNIENLTGSTNNDALTGDDGDNVLAGNAGNDTLQGGAGNDLLRGDEIGSGTAIR
VTVTNTLGEGGTFLTPIWFGFHDGANFDLFTAGEAASLGLERLAEDGSIEGIAAEFNAQTGANGVDGTIIGGAGIPGPID
PGESASLTLNVNANQVGLGFFTWGTMIIPSNDAFLSVPDNPLADPIFDAAGNFIGPVVIERRGSDVLDAGTEVNNELDAA
FLNQTARDTGLDENGVVGAHPGFNGSVGNPDATPVNILGGTTAPGAVIDPVVGDFTADDDLLLRINIERVAIADAGDDLL
EGGEGNDTLEGGGGNDTLTGGAGNDVFVFEADSGANIVTDFDIADDVLDVSAIFSDLDATLGAASQKGNDVAIDFGDNHS
VLLLNIDLTTLRDDNFIFE

Sequences:

>Translated_1539_residues
MTNARFNRFGFHLFGPARLGNSITLGNDGRAYIRKNLIAPVGAPAVDITGNHASLFISRRGSLSAPDSGNTAVLVSGANA
RITNFGSIAGHFNGISSTGGGLRLTNIGTISSNSRAIDLSDGDGIRVTNFGRILGTGNQRNGTLYVDGTVDDLRIFNGHR
GVIDAGVGNLGDAVSVQVGAAGDPSNEDINIVNFGRLQGRGDGDEVFADGTRVTGNGSSGLRFFNGSGLSEATISGSVRN
SGTITAEVNVGFLGGVVVEDGVAFDGRIINGFRGLISGPRNGLYIGNAEHDLEIFNHGRIKSGSRTVNLDGDNVTFINAG
DVVGTGDQRNGTLYLDGTADDISVRNWRRGVIDAGSGNSGSGISIQVGGSSENGLSEGISIDNSGLIRGRGSDNVPAGVR
LFVGSGLDTATFSGTIANNRGGVIASETDAGLLIESGVVFDGQITNRGVIAGGNGFAIDANGALGSVEVTNHGTLDGEVR
LGAGSDRFTQSGRAGVTVTGGLGDDTIVGGRGTDTVRYDDSDVGVTVDLGAGTAERETGFNVTIADLALVNPNDGIDPST
IVEEGIAGNLYFNFHTTDFPSGELRGQLELVADNRDGNGVGTVEFAANLSGDQEVPPVETDASGIATTTFTVGPDGSVAY
STVASLSGITQADLLPVNIGNGTLSPIHLHNAPTGINGPVVVDIASDAGPDGIGADGFNLTVPELALVDPNAGIGADQII
AEGVAGNLYFNFHTNDFPSGEVRGQLELIADNRDADGIGTVEFATDLSGDQEVPPVGTDSSGTATALFTVAPDGSVTYST
SASLVGINPEDLLPVNIGNGTLSPIHLHNAPAGINGPVVINIATDAGPTGLVPIAETDTLTNIENVIGSNDADLLIGDGE
SNTLQGLDGDDALQGGGGNDTLEGGAGDDTLQGGGGNDSLDGGEGTDIASFADIGADVNVTLNADGTGSAEYEVNGRTVT
DTFTSIEGVIGSANNDTIIANGAAGNIIEGGAGDDFIAGAGGTDTLDGGEGNDTNSFINIGAPVVASLASGSASYEVGSG
TVFENFSNFENLDGSAQNDQLFGDGNDNTLAGNDGDDLLSGGGGDDTLLGGLGDDTLQGGGGNDLTDGGDGIDTADFQNI
GADVTADLSTGQAQYIANGNPIQDQLSNIENLTGSTNNDALTGDDGDNVLAGNAGNDTLQGGAGNDLLRGDEIGSGTAIR
VTVTNTLGEGGTFLTPIWFGFHDGANFDLFTAGEAASLGLERLAEDGSIEGIAAEFNAQTGANGVDGTIIGGAGIPGPID
PGESASLTLNVNANQVGLGFFTWGTMIIPSNDAFLSVPDNPLADPIFDAAGNFIGPVVIERRGSDVLDAGTEVNNELDAA
FLNQTARDTGLDENGVVGAHPGFNGSVGNPDATPVNILGGTTAPGAVIDPVVGDFTADDDLLLRINIERVAIADAGDDLL
EGGEGNDTLEGGGGNDTLTGGAGNDVFVFEADSGANIVTDFDIADDVLDVSAIFSDLDATLGAASQKGNDVAIDFGDNHS
VLLLNIDLTTLRDDNFIFE
>Mature_1538_residues
TNARFNRFGFHLFGPARLGNSITLGNDGRAYIRKNLIAPVGAPAVDITGNHASLFISRRGSLSAPDSGNTAVLVSGANAR
ITNFGSIAGHFNGISSTGGGLRLTNIGTISSNSRAIDLSDGDGIRVTNFGRILGTGNQRNGTLYVDGTVDDLRIFNGHRG
VIDAGVGNLGDAVSVQVGAAGDPSNEDINIVNFGRLQGRGDGDEVFADGTRVTGNGSSGLRFFNGSGLSEATISGSVRNS
GTITAEVNVGFLGGVVVEDGVAFDGRIINGFRGLISGPRNGLYIGNAEHDLEIFNHGRIKSGSRTVNLDGDNVTFINAGD
VVGTGDQRNGTLYLDGTADDISVRNWRRGVIDAGSGNSGSGISIQVGGSSENGLSEGISIDNSGLIRGRGSDNVPAGVRL
FVGSGLDTATFSGTIANNRGGVIASETDAGLLIESGVVFDGQITNRGVIAGGNGFAIDANGALGSVEVTNHGTLDGEVRL
GAGSDRFTQSGRAGVTVTGGLGDDTIVGGRGTDTVRYDDSDVGVTVDLGAGTAERETGFNVTIADLALVNPNDGIDPSTI
VEEGIAGNLYFNFHTTDFPSGELRGQLELVADNRDGNGVGTVEFAANLSGDQEVPPVETDASGIATTTFTVGPDGSVAYS
TVASLSGITQADLLPVNIGNGTLSPIHLHNAPTGINGPVVVDIASDAGPDGIGADGFNLTVPELALVDPNAGIGADQIIA
EGVAGNLYFNFHTNDFPSGEVRGQLELIADNRDADGIGTVEFATDLSGDQEVPPVGTDSSGTATALFTVAPDGSVTYSTS
ASLVGINPEDLLPVNIGNGTLSPIHLHNAPAGINGPVVINIATDAGPTGLVPIAETDTLTNIENVIGSNDADLLIGDGES
NTLQGLDGDDALQGGGGNDTLEGGAGDDTLQGGGGNDSLDGGEGTDIASFADIGADVNVTLNADGTGSAEYEVNGRTVTD
TFTSIEGVIGSANNDTIIANGAAGNIIEGGAGDDFIAGAGGTDTLDGGEGNDTNSFINIGAPVVASLASGSASYEVGSGT
VFENFSNFENLDGSAQNDQLFGDGNDNTLAGNDGDDLLSGGGGDDTLLGGLGDDTLQGGGGNDLTDGGDGIDTADFQNIG
ADVTADLSTGQAQYIANGNPIQDQLSNIENLTGSTNNDALTGDDGDNVLAGNAGNDTLQGGAGNDLLRGDEIGSGTAIRV
TVTNTLGEGGTFLTPIWFGFHDGANFDLFTAGEAASLGLERLAEDGSIEGIAAEFNAQTGANGVDGTIIGGAGIPGPIDP
GESASLTLNVNANQVGLGFFTWGTMIIPSNDAFLSVPDNPLADPIFDAAGNFIGPVVIERRGSDVLDAGTEVNNELDAAF
LNQTARDTGLDENGVVGAHPGFNGSVGNPDATPVNILGGTTAPGAVIDPVVGDFTADDDLLLRINIERVAIADAGDDLLE
GGEGNDTLEGGGGNDTLTGGAGNDVFVFEADSGANIVTDFDIADDVLDVSAIFSDLDATLGAASQKGNDVAIDFGDNHSV
LLLNIDLTTLRDDNFIFE

Specific function: This adenylate cyclase belongs to a special class of bacterial toxin. It causes whooping cough by acting on mammalian cells by elevating cAMP-concentration and thus disrupts normal cell function [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 17 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005165
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR018504
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF03497 Anthrax_toxA; PF00353 HemolysinCabind; PF02382 RTX [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 154789; Mature: 154658

Theoretical pI: Translated: 3.66; Mature: 3.66

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.1 %Met     (Translated Protein)
0.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.1 %Met     (Mature Protein)
0.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNARFNRFGFHLFGPARLGNSITLGNDGRAYIRKNLIAPVGAPAVDITGNHASLFISRR
CCCCCCCCCCEEEEEHHHCCCEEEECCCCHHHHHHCCCCCCCCCEEEEECCCEEEEEEEC
GSLSAPDSGNTAVLVSGANARITNFGSIAGHFNGISSTGGGLRLTNIGTISSNSRAIDLS
CCCCCCCCCCEEEEEECCCCEEEECCCHHCCCCCCCCCCCCEEEEEEEEECCCCEEEECC
DGDGIRVTNFGRILGTGNQRNGTLYVDGTVDDLRIFNGHRGVIDAGVGNLGDAVSVQVGA
CCCCEEEEECCEEEECCCCCCCEEEECCCCCEEEEECCCCCEEECCCCCCCCEEEEEEEC
AGDPSNEDINIVNFGRLQGRGDGDEVFADGTRVTGNGSSGLRFFNGSGLSEATISGSVRN
CCCCCCCCEEEEEEEEECCCCCCCEEEECCEEEECCCCCCEEEECCCCCCCEEEECCCCC
SGTITAEVNVGFLGGVVVEDGVAFDGRIINGFRGLISGPRNGLYIGNAEHDLEIFNHGRI
CCEEEEEEECEEECCEEEECCCEECCEEEECHHHHHCCCCCCEEECCCCCCEEEEECCCC
KSGSRTVNLDGDNVTFINAGDVVGTGDQRNGTLYLDGTADDISVRNWRRGVIDAGSGNSG
CCCCEEEEECCCCEEEEECCCEEECCCCCCCEEEECCCCCCCCCCCCCCCEEECCCCCCC
SGISIQVGGSSENGLSEGISIDNSGLIRGRGSDNVPAGVRLFVGSGLDTATFSGTIANNR
CEEEEEECCCCCCCHHCCCEECCCCEEECCCCCCCCCCEEEEEECCCCCEEEEEEEECCC
GGVIASETDAGLLIESGVVFDGQITNRGVIAGGNGFAIDANGALGSVEVTNHGTLDGEVR
CCEEEECCCCCEEEECCEEEECEECCCCEEECCCEEEEECCCCEEEEEECCCCCCCCEEE
LGAGSDRFTQSGRAGVTVTGGLGDDTIVGGRGTDTVRYDDSDVGVTVDLGAGTAERETGF
ECCCCCHHHCCCCCCEEEECCCCCCEEECCCCCCEEEECCCCCCEEEECCCCCCCCCCCC
NVTIADLALVNPNDGIDPSTIVEEGIAGNLYFNFHTTDFPSGELRGQLELVADNRDGNGV
EEEEEEEEEECCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCCCCE
GTVEFAANLSGDQEVPPVETDASGIATTTFTVGPDGSVAYSTVASLSGITQADLLPVNIG
EEEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEECC
NGTLSPIHLHNAPTGINGPVVVDIASDAGPDGIGADGFNLTVPELALVDPNAGIGADQII
CCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCEEEEECCCCCCCHHHHH
AEGVAGNLYFNFHTNDFPSGEVRGQLELIADNRDADGIGTVEFATDLSGDQEVPPVGTDS
HCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCC
SGTATALFTVAPDGSVTYSTSASLVGINPEDLLPVNIGNGTLSPIHLHNAPAGINGPVVI
CCCEEEEEEECCCCCEEEECCCEEEECCHHHEEEEECCCCCCCEEEECCCCCCCCCCEEE
NIATDAGPTGLVPIAETDTLTNIENVIGSNDADLLIGDGESNTLQGLDGDDALQGGGGND
EEECCCCCCCEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCEECCCCCCHHCCCCCCCC
TLEGGAGDDTLQGGGGNDSLDGGEGTDIASFADIGADVNVTLNADGTGSAEYEVNGRTVT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCEEEEECCCEEE
DTFTSIEGVIGSANNDTIIANGAAGNIIEGGAGDDFIAGAGGTDTLDGGEGNDTNSFINI
EHHHHHHHEEECCCCCEEEECCCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEE
GAPVVASLASGSASYEVGSGTVFENFSNFENLDGSAQNDQLFGDGNDNTLAGNDGDDLLS
CCHHHHHHHCCCCEEEECCCEEECCCCCHHCCCCCCCCCEEEECCCCCEECCCCCHHHHC
GGGGDDTLLGGLGDDTLQGGGGNDLTDGGDGIDTADFQNIGADVTADLSTGQAQYIANGN
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEECCCCCEEEEECCC
PIQDQLSNIENLTGSTNNDALTGDDGDNVLAGNAGNDTLQGGAGNDLLRGDEIGSGTAIR
CHHHHHHHHHHHCCCCCCCEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEE
VTVTNTLGEGGTFLTPIWFGFHDGANFDLFTAGEAASLGLERLAEDGSIEGIAAEFNAQT
EEEEECCCCCCCEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEEECCCC
GANGVDGTIIGGAGIPGPIDPGESASLTLNVNANQVGLGFFTWGTMIIPSNDAFLSVPDN
CCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEEEEECEEEEECCCCEEECCCC
PLADPIFDAAGNFIGPVVIERRGSDVLDAGTEVNNELDAAFLNQTARDTGLDENGVVGAH
CCCCHHHHHCCCCCCCEEEEECCCCHHHCCCCCCCCHHHHHHHCHHHHCCCCCCCEEECC
PGFNGSVGNPDATPVNILGGTTAPGAVIDPVVGDFTADDDLLLRINIERVAIADAGDDLL
CCCCCCCCCCCCCEEEEECCCCCCCCEECCCCCCCCCCCCEEEEEEEEEEEEECCCHHHH
EGGEGNDTLEGGGGNDTLTGGAGNDVFVFEADSGANIVTDFDIADDVLDVSAIFSDLDAT
CCCCCCCCCCCCCCCCCEECCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHH
LGAASQKGNDVAIDFGDNHSVLLLNIDLTTLRDDNFIFE
HCCCCCCCCEEEEEECCCCCEEEEEEEEEEEECCCEEEC
>Mature Secondary Structure 
TNARFNRFGFHLFGPARLGNSITLGNDGRAYIRKNLIAPVGAPAVDITGNHASLFISRR
CCCCCCCCCEEEEEHHHCCCEEEECCCCHHHHHHCCCCCCCCCEEEEECCCEEEEEEEC
GSLSAPDSGNTAVLVSGANARITNFGSIAGHFNGISSTGGGLRLTNIGTISSNSRAIDLS
CCCCCCCCCCEEEEEECCCCEEEECCCHHCCCCCCCCCCCCEEEEEEEEECCCCEEEECC
DGDGIRVTNFGRILGTGNQRNGTLYVDGTVDDLRIFNGHRGVIDAGVGNLGDAVSVQVGA
CCCCEEEEECCEEEECCCCCCCEEEECCCCCEEEEECCCCCEEECCCCCCCCEEEEEEEC
AGDPSNEDINIVNFGRLQGRGDGDEVFADGTRVTGNGSSGLRFFNGSGLSEATISGSVRN
CCCCCCCCEEEEEEEEECCCCCCCEEEECCEEEECCCCCCEEEECCCCCCCEEEECCCCC
SGTITAEVNVGFLGGVVVEDGVAFDGRIINGFRGLISGPRNGLYIGNAEHDLEIFNHGRI
CCEEEEEEECEEECCEEEECCCEECCEEEECHHHHHCCCCCCEEECCCCCCEEEEECCCC
KSGSRTVNLDGDNVTFINAGDVVGTGDQRNGTLYLDGTADDISVRNWRRGVIDAGSGNSG
CCCCEEEEECCCCEEEEECCCEEECCCCCCCEEEECCCCCCCCCCCCCCCEEECCCCCCC
SGISIQVGGSSENGLSEGISIDNSGLIRGRGSDNVPAGVRLFVGSGLDTATFSGTIANNR
CEEEEEECCCCCCCHHCCCEECCCCEEECCCCCCCCCCEEEEEECCCCCEEEEEEEECCC
GGVIASETDAGLLIESGVVFDGQITNRGVIAGGNGFAIDANGALGSVEVTNHGTLDGEVR
CCEEEECCCCCEEEECCEEEECEECCCCEEECCCEEEEECCCCEEEEEECCCCCCCCEEE
LGAGSDRFTQSGRAGVTVTGGLGDDTIVGGRGTDTVRYDDSDVGVTVDLGAGTAERETGF
ECCCCCHHHCCCCCCEEEECCCCCCEEECCCCCCEEEECCCCCCEEEECCCCCCCCCCCC
NVTIADLALVNPNDGIDPSTIVEEGIAGNLYFNFHTTDFPSGELRGQLELVADNRDGNGV
EEEEEEEEEECCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCCCCE
GTVEFAANLSGDQEVPPVETDASGIATTTFTVGPDGSVAYSTVASLSGITQADLLPVNIG
EEEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEECC
NGTLSPIHLHNAPTGINGPVVVDIASDAGPDGIGADGFNLTVPELALVDPNAGIGADQII
CCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCEEEEECCCCCCCHHHHH
AEGVAGNLYFNFHTNDFPSGEVRGQLELIADNRDADGIGTVEFATDLSGDQEVPPVGTDS
HCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCC
SGTATALFTVAPDGSVTYSTSASLVGINPEDLLPVNIGNGTLSPIHLHNAPAGINGPVVI
CCCEEEEEEECCCCCEEEECCCEEEECCHHHEEEEECCCCCCCEEEECCCCCCCCCCEEE
NIATDAGPTGLVPIAETDTLTNIENVIGSNDADLLIGDGESNTLQGLDGDDALQGGGGND
EEECCCCCCCEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCEECCCCCCHHCCCCCCCC
TLEGGAGDDTLQGGGGNDSLDGGEGTDIASFADIGADVNVTLNADGTGSAEYEVNGRTVT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCEEEEECCCEEE
DTFTSIEGVIGSANNDTIIANGAAGNIIEGGAGDDFIAGAGGTDTLDGGEGNDTNSFINI
EHHHHHHHEEECCCCCEEEECCCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEE
GAPVVASLASGSASYEVGSGTVFENFSNFENLDGSAQNDQLFGDGNDNTLAGNDGDDLLS
CCHHHHHHHCCCCEEEECCCEEECCCCCHHCCCCCCCCCEEEECCCCCEECCCCCHHHHC
GGGGDDTLLGGLGDDTLQGGGGNDLTDGGDGIDTADFQNIGADVTADLSTGQAQYIANGN
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEECCCCCEEEEECCC
PIQDQLSNIENLTGSTNNDALTGDDGDNVLAGNAGNDTLQGGAGNDLLRGDEIGSGTAIR
CHHHHHHHHHHHCCCCCCCEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEE
VTVTNTLGEGGTFLTPIWFGFHDGANFDLFTAGEAASLGLERLAEDGSIEGIAAEFNAQT
EEEEECCCCCCCEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEEECCCC
GANGVDGTIIGGAGIPGPIDPGESASLTLNVNANQVGLGFFTWGTMIIPSNDAFLSVPDN
CCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEEEEECEEEEECCCCEEECCCC
PLADPIFDAAGNFIGPVVIERRGSDVLDAGTEVNNELDAAFLNQTARDTGLDENGVVGAH
CCCCHHHHHCCCCCCCEEEEECCCCHHHCCCCCCCCHHHHHHHCHHHHCCCCCCCEEECC
PGFNGSVGNPDATPVNILGGTTAPGAVIDPVVGDFTADDDLLLRINIERVAIADAGDDLL
CCCCCCCCCCCCCEEEEECCCCCCCCEECCCCCCCCCCCCEEEEEEEEEEEEECCCHHHH
EGGEGNDTLEGGGGNDTLTGGAGNDVFVFEADSGANIVTDFDIADDVLDVSAIFSDLDAT
CCCCCCCCCCCCCCCCCEECCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHH
LGAASQKGNDVAIDFGDNHSVLLLNIDLTTLRDDNFIFE
HCCCCCCCCEEEEEECCCCCEEEEEEEEEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7557410; 12910271 [H]