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The map label for this gene is macB [H]

Identifier: 158338146

GI number: 158338146

Start: 5086938

End: 5088200

Strand: Direct

Name: macB [H]

Synonym: AM1_5038

Alternate gene names: 158338146

Gene position: 5086938-5088200 (Clockwise)

Preceding gene: 158338145

Following gene: 158338147

Centisome position: 78.22

GC content: 48.93

Gene sequence:

>1263_bases
ATGGCAGTTTTCAAATCCAAGCCTCAGCGGATTTCAGCCTTTGAAATTGGAGAAATGGCAATTGTCGCACTCTGGGACAA
CAAGCTCCGCAGTGGACTGACGATGTTGGGCGTGATTATCGGCATCGGTTCAGTTATTTCAATTTCCTCCATCGGTCAGG
GGATTCAGCAATCGACTGAAGATAGTATTCGCAGCCTGGGTACGGATGTGTTGCAGGTGATGGCAGGGTCAGCGAAAAGC
GGTGGGGTTAGCCAAGGTCAGGGGTCGATCACAACCCTGACTTGGGAAGATGCTAAAGCGATAGAAGCCCAAGCACCCTC
TGCAACTGTTGTTTCAGCATACTTACAGCGCAATACTCAAGTTGTCTATGGTGAAGAAAACACGGCCACCACAGTCTATG
GTGCTGATCTCAGCTATCCCGAAGCCCGCAATACTTTCCCAAAAACAGGACGATTCTTTACTGCAGAGGAACTGGAAACC
GCCGCTTCAGTAGTCGTAATTGCCCCTACCGTTCAAAGCAATTTATTCCCTAATCACGTCAATCCCATTGGTGAAAAGCT
GCGGATTCAGGGAGAGATATACGAGATAATTGGGGTGATGGAAGCTAAAGGCTCTCAAGGTCCCATTGATCGCGATGATG
CAGTCTATATCCCCCTGACCAGTATGTCGGCTCGGATTATCGGTAACAATGCCCTGATTGGTGTATCAGTAAATGGAATC
TATATTAAGGGCCAGGACGAATCTCAACTCGATATTGTCAAGTTCCAGGTGGAGAATATCCTCCGCCTTCGGCATAATAT
TTCCTCTCCTGCAGAGGATGATTTCCGGATTACAAATCAGGCCGATATTCTGCAAACCTTCACCACAATTTTGGGTTTGC
TAACAATCATGATTGTGACCATTGCTGGGATCTCCCTGGTCGTGGGAGGGATTGGCATTGCCAACATCATGTTGGTGTCT
GTAGTAGAACGCACACGGGAGATTGGAATTCGCAAAGCGTTAGGGGCTACGGATGGAGCAATTCTGAGCCAATTTCTAAC
GGAGTCGGTGGTGATTTCCGTCGTGGGGGGTGTAATTGGCATTGTTCTGGGGGTAGGCATCACCTTTATTTCAGCGACTG
CCTTTGGCTTTACTTTTATTGTGTCCAGTAGTGCGGTGGCGATTGGTGTTGGTTTATCCACTACGGTTGGCTTAGTCGCA
GGGGTTATTCCCGCTCGCAACGCAGCCCGACTCGACCCCATTGAGGCTCTTCGCAGTGATTAG

Upstream 100 bases:

>100_bases
GGCTGAAGGGGCAAGAGAGAGTGTTGATCAGTCCGCCTACAGAGTCAAAATCAGGACCTAACCGACGGCTTCCCTTTGGT
CCGCGTCCTCAGGAGTAGTT

Downstream 100 bases:

>100_bases
GTGTCTAAAGCGAGCGTGTCAGCCATGATTATTCTGGAAAATATTACCAAATGCTATCAACTGGGTGACAATCAAGTCCC
CATTTTGAGAGGAATCGACC

Product: macrolide export ATP-binding/permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MAVFKSKPQRISAFEIGEMAIVALWDNKLRSGLTMLGVIIGIGSVISISSIGQGIQQSTEDSIRSLGTDVLQVMAGSAKS
GGVSQGQGSITTLTWEDAKAIEAQAPSATVVSAYLQRNTQVVYGEENTATTVYGADLSYPEARNTFPKTGRFFTAEELET
AASVVVIAPTVQSNLFPNHVNPIGEKLRIQGEIYEIIGVMEAKGSQGPIDRDDAVYIPLTSMSARIIGNNALIGVSVNGI
YIKGQDESQLDIVKFQVENILRLRHNISSPAEDDFRITNQADILQTFTTILGLLTIMIVTIAGISLVVGGIGIANIMLVS
VVERTREIGIRKALGATDGAILSQFLTESVVISVVGGVIGIVLGVGITFISATAFGFTFIVSSSAVAIGVGLSTTVGLVA
GVIPARNAARLDPIEALRSD

Sequences:

>Translated_420_residues
MAVFKSKPQRISAFEIGEMAIVALWDNKLRSGLTMLGVIIGIGSVISISSIGQGIQQSTEDSIRSLGTDVLQVMAGSAKS
GGVSQGQGSITTLTWEDAKAIEAQAPSATVVSAYLQRNTQVVYGEENTATTVYGADLSYPEARNTFPKTGRFFTAEELET
AASVVVIAPTVQSNLFPNHVNPIGEKLRIQGEIYEIIGVMEAKGSQGPIDRDDAVYIPLTSMSARIIGNNALIGVSVNGI
YIKGQDESQLDIVKFQVENILRLRHNISSPAEDDFRITNQADILQTFTTILGLLTIMIVTIAGISLVVGGIGIANIMLVS
VVERTREIGIRKALGATDGAILSQFLTESVVISVVGGVIGIVLGVGITFISATAFGFTFIVSSSAVAIGVGLSTTVGLVA
GVIPARNAARLDPIEALRSD
>Mature_419_residues
AVFKSKPQRISAFEIGEMAIVALWDNKLRSGLTMLGVIIGIGSVISISSIGQGIQQSTEDSIRSLGTDVLQVMAGSAKSG
GVSQGQGSITTLTWEDAKAIEAQAPSATVVSAYLQRNTQVVYGEENTATTVYGADLSYPEARNTFPKTGRFFTAEELETA
ASVVVIAPTVQSNLFPNHVNPIGEKLRIQGEIYEIIGVMEAKGSQGPIDRDDAVYIPLTSMSARIIGNNALIGVSVNGIY
IKGQDESQLDIVKFQVENILRLRHNISSPAEDDFRITNQADILQTFTTILGLLTIMIVTIAGISLVVGGIGIANIMLVSV
VERTREIGIRKALGATDGAILSQFLTESVVISVVGGVIGIVLGVGITFISATAFGFTFIVSSSAVAIGVGLSTTVGLVAG
VIPARNAARLDPIEALRSD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=411, Percent_Identity=36.4963503649635, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44156; Mature: 44025

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFKSKPQRISAFEIGEMAIVALWDNKLRSGLTMLGVIIGIGSVISISSIGQGIQQSTE
CCCCCCCCCEECEEECCCEEEEEEECHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
DSIRSLGTDVLQVMAGSAKSGGVSQGQGSITTLTWEDAKAIEAQAPSATVVSAYLQRNTQ
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCHHHHHHHHHCCCE
VVYGEENTATTVYGADLSYPEARNTFPKTGRFFTAEELETAASVVVIAPTVQSNLFPNHV
EEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHCCEEEEEECHHCCCCCCCC
NPIGEKLRIQGEIYEIIGVMEAKGSQGPIDRDDAVYIPLTSMSARIIGNNALIGVSVNGI
CCCCHHEEECHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEECCCEEEEEEEEEE
YIKGQDESQLDIVKFQVENILRLRHNISSPAEDDFRITNQADILQTFTTILGLLTIMIVT
EEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
IAGISLVVGGIGIANIMLVSVVERTREIGIRKALGATDGAILSQFLTESVVISVVGGVIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
IVLGVGITFISATAFGFTFIVSSSAVAIGVGLSTTVGLVAGVIPARNAARLDPIEALRSD
HHHHHHHHHHHHHHHHHHHEECCCCEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHCC
>Mature Secondary Structure 
AVFKSKPQRISAFEIGEMAIVALWDNKLRSGLTMLGVIIGIGSVISISSIGQGIQQSTE
CCCCCCCCEECEEECCCEEEEEEECHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
DSIRSLGTDVLQVMAGSAKSGGVSQGQGSITTLTWEDAKAIEAQAPSATVVSAYLQRNTQ
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCHHHHHHHHHCCCE
VVYGEENTATTVYGADLSYPEARNTFPKTGRFFTAEELETAASVVVIAPTVQSNLFPNHV
EEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHCCEEEEEECHHCCCCCCCC
NPIGEKLRIQGEIYEIIGVMEAKGSQGPIDRDDAVYIPLTSMSARIIGNNALIGVSVNGI
CCCCHHEEECHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEECCCEEEEEEEEEE
YIKGQDESQLDIVKFQVENILRLRHNISSPAEDDFRITNQADILQTFTTILGLLTIMIVT
EEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
IAGISLVVGGIGIANIMLVSVVERTREIGIRKALGATDGAILSQFLTESVVISVVGGVIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
IVLGVGITFISATAFGFTFIVSSSAVAIGVGLSTTVGLVAGVIPARNAARLDPIEALRSD
HHHHHHHHHHHHHHHHHHHEECCCCEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA