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The map label for this gene is udp [H]

Identifier: 158338123

GI number: 158338123

Start: 5058605

End: 5059375

Strand: Reverse

Name: udp [H]

Synonym: AM1_5014

Alternate gene names: 158338123

Gene position: 5059375-5058605 (Counterclockwise)

Preceding gene: 158338125

Following gene: 158338119

Centisome position: 77.79

GC content: 46.56

Gene sequence:

>771_bases
ATGGGCTCAACACTGTACCACATTGGTTTTAACCGGGATGACCTTGGTAGCAATCCCCCAACATTGGCTTTATTATCGGG
CGATCCTCAACGCGCCTATCAAATTGCCGACCAATATTTAGAAAATGTGCAGCGACTATCAGAAAATCGTGGTCTGCATA
GCTATTGGGGAGTCTTACCCAACGGATGTCCCATATTATCTGCAACGAGCGGAATGGGTGCCCCTTCCTTGAGTATTGTC
GTTAATGAATTAGTCCAAATTGGCATCAAGAAAATTATTCGCATCGGCACCTGTGGTTCCATCCAAGACCATGTCAAAAC
AGGCAGTATCGTTATTTCTCAGGCCGCACTCTGTCGCCAAGGAGCTGCCAACGATATTGCACCCATCGAATATCCGGCCT
CTGCTGATCCATTTCTGACTGTCGCCTTAGTTCAAGCCGCCAAAGAACTAGAACTCACCCATCATCTGGGGATTACGGCA
TCGGTAGATACGTTTTATGAAGGCCAAGAACGAACCGATTCTGCAAACCCAACTCTGCTGCGTTCTCTGCAAAACATCAC
AGAAGAATACCGAGCATTAAACATCCTCAACTACGAAATGGAAGCAGGCACCTTATTCAAAATGGCGGGTGTCTATCATT
TTGCTGCGGCTTGTGTCTGCGGTGTCTTAGCCCAGAGAACACGACATGAACAGATAGATCTCGACCATAAAGATTTGGCA
ATTGATAGCGCGATTAGAGTCGCGATTTTAACTGCCCAGAACTGTGAATAA

Upstream 100 bases:

>100_bases
AGAACTATCTCCAAAAGTCGTTATCTCTGCTAAAGTCCATTAGGTATGAATTGAATACCCCCAGGTCTTTTGGATTTATT
CCCCCAACTCATCATATGAA

Downstream 100 bases:

>100_bases
TGATGGAGGGATTTACAACTAAAGACCCTACCCCAGCCTTCAACTTCTCTTGAACATTCCAGCTGGCATCGGCCAATTAA
CGTTCCATCACTAACTCATC

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MGSTLYHIGFNRDDLGSNPPTLALLSGDPQRAYQIADQYLENVQRLSENRGLHSYWGVLPNGCPILSATSGMGAPSLSIV
VNELVQIGIKKIIRIGTCGSIQDHVKTGSIVISQAALCRQGAANDIAPIEYPASADPFLTVALVQAAKELELTHHLGITA
SVDTFYEGQERTDSANPTLLRSLQNITEEYRALNILNYEMEAGTLFKMAGVYHFAAACVCGVLAQRTRHEQIDLDHKDLA
IDSAIRVAILTAQNCE

Sequences:

>Translated_256_residues
MGSTLYHIGFNRDDLGSNPPTLALLSGDPQRAYQIADQYLENVQRLSENRGLHSYWGVLPNGCPILSATSGMGAPSLSIV
VNELVQIGIKKIIRIGTCGSIQDHVKTGSIVISQAALCRQGAANDIAPIEYPASADPFLTVALVQAAKELELTHHLGITA
SVDTFYEGQERTDSANPTLLRSLQNITEEYRALNILNYEMEAGTLFKMAGVYHFAAACVCGVLAQRTRHEQIDLDHKDLA
IDSAIRVAILTAQNCE
>Mature_255_residues
GSTLYHIGFNRDDLGSNPPTLALLSGDPQRAYQIADQYLENVQRLSENRGLHSYWGVLPNGCPILSATSGMGAPSLSIVV
NELVQIGIKKIIRIGTCGSIQDHVKTGSIVISQAALCRQGAANDIAPIEYPASADPFLTVALVQAAKELELTHHLGITAS
VDTFYEGQERTDSANPTLLRSLQNITEEYRALNILNYEMEAGTLFKMAGVYHFAAACVCGVLAQRTRHEQIDLDHKDLAI
DSAIRVAILTAQNCE

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI31742508, Length=182, Percent_Identity=31.8681318681319, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI4507839, Length=182, Percent_Identity=31.8681318681319, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1790265, Length=252, Percent_Identity=36.9047619047619, Blast_Score=180, Evalue=9e-47,
Organism=Escherichia coli, GI1790844, Length=233, Percent_Identity=31.3304721030043, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 27735; Mature: 27604

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSTLYHIGFNRDDLGSNPPTLALLSGDPQRAYQIADQYLENVQRLSENRGLHSYWGVLP
CCCEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
NGCPILSATSGMGAPSLSIVVNELVQIGIKKIIRIGTCGSIQDHVKTGSIVISQAALCRQ
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHC
GAANDIAPIEYPASADPFLTVALVQAAKELELTHHLGITASVDTFYEGQERTDSANPTLL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHCCCCCCCCCCHHHH
RSLQNITEEYRALNILNYEMEAGTLFKMAGVYHFAAACVCGVLAQRTRHEQIDLDHKDLA
HHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
IDSAIRVAILTAQNCE
HHHHHEEEEEECCCCC
>Mature Secondary Structure 
GSTLYHIGFNRDDLGSNPPTLALLSGDPQRAYQIADQYLENVQRLSENRGLHSYWGVLP
CCEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
NGCPILSATSGMGAPSLSIVVNELVQIGIKKIIRIGTCGSIQDHVKTGSIVISQAALCRQ
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHC
GAANDIAPIEYPASADPFLTVALVQAAKELELTHHLGITASVDTFYEGQERTDSANPTLL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHCCCCCCCCCCHHHH
RSLQNITEEYRALNILNYEMEAGTLFKMAGVYHFAAACVCGVLAQRTRHEQIDLDHKDLA
HHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
IDSAIRVAILTAQNCE
HHHHHEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2674901; 1379743; 9278503; 8506346; 8899705; 9661793; 7796917; 12499542 [H]