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The map label for this gene is ubiG [H]

Identifier: 158338121

GI number: 158338121

Start: 5057780

End: 5058514

Strand: Direct

Name: ubiG [H]

Synonym: AM1_5013

Alternate gene names: 158338121

Gene position: 5057780-5058514 (Clockwise)

Preceding gene: 158338120

Following gene: 158338122

Centisome position: 77.77

GC content: 48.71

Gene sequence:

>735_bases
ATGGAGCGCAACAACCTCGCCTTTTACGACCAACAAGCTGACCAGTGGTGGAATGAGACCGCAACCATCTTCCCCCTGAG
TAAGCTGAATCCCCTGCGGTTTCAGTATTTTGATCGGTTTATCCAGGATTGGAATGGACTTAAAGTTTTAGATGTGGGCT
GTGGGGGTGGATATACCTGTGAATTTTTGGCCCAGCGAGGAGCAACGGTGACTGGAATTGATCCGTCTGCTGCCTGCATT
GAAGCGGCAAAACGCCATGCTGAACAGATGGGGTTGACCATTGACTACCACGTTGGCATGGGAGAAACCCTGCCATTCGG
AAATGATTGCTTTGACGTCGTGGTTTGTGTGGATGTGTTGGAACATGTCAAGAGTGTTGCCACTACGGTGACAGAAATTA
GCCGAGTAATAGGTCCAGGAGGGCTATTCTGCTTTGATACCATCAACCGTACTTGGCAGTCTCGCTGGCTGATGATCTGG
CTACTAGAAGATGTACTGCGACAAATTCCTCGGGGAATTCATGATTGGCATCAGTTTGTTCCCCCAGAAGACTTGCATCA
ACAGTTGGTGCATGTTGGGTTTTCACAAGTTACCCTCCAGGGATTTGATCTATTTGGCCGAACACCTCTAGCCCAGATAT
CCAACTTGATTCACTTTCTAAAGACGGGGGAGTTTCGGGTTCAATTCGATGACAACACTGGAGTCATGTACATCGGTGCG
GCTCAGATGAGTTAG

Upstream 100 bases:

>100_bases
ATCTACCCTATAGTTGGGATCTCAATCAATGCCTATCTTCGTAACGGTGCTCGGCTGGGTTCAAGATCGAATACGATTAA
GGACCTGATCGACAGAGAGT

Downstream 100 bases:

>100_bases
TGATGGAACGTTAATTGGCCGATGCCAGCTGGAATGTTCAAGAGAAGTTGAAGGCTGGGGTAGGGTCTTTAGTTGTAAAT
CCCTCCATCATTATTCACAG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MERNNLAFYDQQADQWWNETATIFPLSKLNPLRFQYFDRFIQDWNGLKVLDVGCGGGYTCEFLAQRGATVTGIDPSAACI
EAAKRHAEQMGLTIDYHVGMGETLPFGNDCFDVVVCVDVLEHVKSVATTVTEISRVIGPGGLFCFDTINRTWQSRWLMIW
LLEDVLRQIPRGIHDWHQFVPPEDLHQQLVHVGFSQVTLQGFDLFGRTPLAQISNLIHFLKTGEFRVQFDDNTGVMYIGA
AQMS

Sequences:

>Translated_244_residues
MERNNLAFYDQQADQWWNETATIFPLSKLNPLRFQYFDRFIQDWNGLKVLDVGCGGGYTCEFLAQRGATVTGIDPSAACI
EAAKRHAEQMGLTIDYHVGMGETLPFGNDCFDVVVCVDVLEHVKSVATTVTEISRVIGPGGLFCFDTINRTWQSRWLMIW
LLEDVLRQIPRGIHDWHQFVPPEDLHQQLVHVGFSQVTLQGFDLFGRTPLAQISNLIHFLKTGEFRVQFDDNTGVMYIGA
AQMS
>Mature_244_residues
MERNNLAFYDQQADQWWNETATIFPLSKLNPLRFQYFDRFIQDWNGLKVLDVGCGGGYTCEFLAQRGATVTGIDPSAACI
EAAKRHAEQMGLTIDYHVGMGETLPFGNDCFDVVVCVDVLEHVKSVATTVTEISRVIGPGGLFCFDTINRTWQSRWLMIW
LLEDVLRQIPRGIHDWHQFVPPEDLHQQLVHVGFSQVTLQGFDLFGRTPLAQISNLIHFLKTGEFRVQFDDNTGVMYIGA
AQMS

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=204, Percent_Identity=34.8039215686275, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI1788564, Length=187, Percent_Identity=36.8983957219251, Blast_Score=128, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI115533050, Length=204, Percent_Identity=29.4117647058824, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324476, Length=145, Percent_Identity=32.4137931034483, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24585589, Length=221, Percent_Identity=30.7692307692308, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI281365311, Length=221, Percent_Identity=30.316742081448, Blast_Score=106, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 27678; Mature: 27678

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERNNLAFYDQQADQWWNETATIFPLSKLNPLRFQYFDRFIQDWNGLKVLDVGCGGGYTC
CCCCCCEEEECHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHH
EFLAQRGATVTGIDPSAACIEAAKRHAEQMGLTIDYHVGMGETLPFGNDCFDVVVCVDVL
HHHHHCCCEEECCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
EHVKSVATTVTEISRVIGPGGLFCFDTINRTWQSRWLMIWLLEDVLRQIPRGIHDWHQFV
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPEDLHQQLVHVGFSQVTLQGFDLFGRTPLAQISNLIHFLKTGEFRVQFDDNTGVMYIGA
CCHHHHHHHHHCCHHHHEEEHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEE
AQMS
CCCC
>Mature Secondary Structure
MERNNLAFYDQQADQWWNETATIFPLSKLNPLRFQYFDRFIQDWNGLKVLDVGCGGGYTC
CCCCCCEEEECHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHH
EFLAQRGATVTGIDPSAACIEAAKRHAEQMGLTIDYHVGMGETLPFGNDCFDVVVCVDVL
HHHHHCCCEEECCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
EHVKSVATTVTEISRVIGPGGLFCFDTINRTWQSRWLMIWLLEDVLRQIPRGIHDWHQFV
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPEDLHQQLVHVGFSQVTLQGFDLFGRTPLAQISNLIHFLKTGEFRVQFDDNTGVMYIGA
CCHHHHHHHHHCCHHHHEEEHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEE
AQMS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]