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The map label for this gene is hslO

Identifier: 158338084

GI number: 158338084

Start: 5017860

End: 5018759

Strand: Direct

Name: hslO

Synonym: AM1_4974

Alternate gene names: 158338084

Gene position: 5017860-5018759 (Clockwise)

Preceding gene: 158338081

Following gene: 158338086

Centisome position: 77.15

GC content: 50.0

Gene sequence:

>900_bases
ATGGCCGACCAACTTATTCGAGCCACAGCTGCTGATGATGGCATCCGAGCAGTTGGTGTGATCACCACTCGTTTAACCGA
AGATGCAAGACAACGTCATGGCCTCTCCTATGTCGCAACTGCTGCTTTAGGCCGGACTATGTCTGCTGGATTATTGTTGG
CGTCCAGCATGAAACAAGCAGAAGCAAGGATTAATCTCCGTATTCGTGGGGATGGGCCATTGCAAGGCATTTTAGTGGAT
GCTGGCTTAGACGGTACGGTCCGCGGATATGTCACCAATCCTGGGGTAGAACTCCCCCCCAATGCGAAGGGCAAGCTGGA
TGTGGGAGGGGCTGTCGGTAAAGGTTTTCTCTATGTGATACGGGATATGGGATATGGATACCCCTATTCCAGCACGGTGG
AATTAGTCTCCGGTGAGATAGGCGAAGATGTTACTCACTATCTGGTCACTTCAGAGCAAACCCCATCTGCTCTTGCTTTG
GGGGTTTTTGTCGGGGCTCAAGGAGTCACTGCGTCTGGGGGACTGTTGATCCAAGTTTTACCAAAAGCAGCTGAAGATCC
GGCCCTTGTGGAATTACTAGAGTCTCGCCTTGCTCACTTGCAAGGCTTTACTCCCTTACTGCAAGCTGGCAAAACGCTTC
CTGATATCTTTACGGACTTGCTAGGGGATATGGGACTTAAGATATTTCCCCAAACTCAAATGGTGCAATTCCAGTGCCGC
TGCTCAACTGAGCGAGTGCTCGGGGCCTTGAAAATGCTCGGGCAAGATGAACTGCTAGACATGATTGAAAAGGATGATGG
GGCAGAAGCAACTTGTGATTTTTGTGGTGAGGTCTATCAGGTTACCAGCGATCAGCTAGGAAAACTGATTGATGATTTAA
AAACCGAAGCAGGGGCCTAG

Upstream 100 bases:

>100_bases
CTTGGCAACATAACGCTCTAATGTATCTACTTTCCAAGGCTTCACTTGAAGTTCATTGCAGTACAATTAAAAAGATTTAT
TAAGAACCTGTAGGGATTCT

Downstream 100 bases:

>100_bases
TTCTAGACCCCTGTCTTATTTCAAGCTAGAGACAGAGTAGAATCCCGTCTCTGTTCTCTAGATTTGAATGCTGCCCCCAT
CATAGAGGGGAACGGTCATT

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MADQLIRATAADDGIRAVGVITTRLTEDARQRHGLSYVATAALGRTMSAGLLLASSMKQAEARINLRIRGDGPLQGILVD
AGLDGTVRGYVTNPGVELPPNAKGKLDVGGAVGKGFLYVIRDMGYGYPYSSTVELVSGEIGEDVTHYLVTSEQTPSALAL
GVFVGAQGVTASGGLLIQVLPKAAEDPALVELLESRLAHLQGFTPLLQAGKTLPDIFTDLLGDMGLKIFPQTQMVQFQCR
CSTERVLGALKMLGQDELLDMIEKDDGAEATCDFCGEVYQVTSDQLGKLIDDLKTEAGA

Sequences:

>Translated_299_residues
MADQLIRATAADDGIRAVGVITTRLTEDARQRHGLSYVATAALGRTMSAGLLLASSMKQAEARINLRIRGDGPLQGILVD
AGLDGTVRGYVTNPGVELPPNAKGKLDVGGAVGKGFLYVIRDMGYGYPYSSTVELVSGEIGEDVTHYLVTSEQTPSALAL
GVFVGAQGVTASGGLLIQVLPKAAEDPALVELLESRLAHLQGFTPLLQAGKTLPDIFTDLLGDMGLKIFPQTQMVQFQCR
CSTERVLGALKMLGQDELLDMIEKDDGAEATCDFCGEVYQVTSDQLGKLIDDLKTEAGA
>Mature_298_residues
ADQLIRATAADDGIRAVGVITTRLTEDARQRHGLSYVATAALGRTMSAGLLLASSMKQAEARINLRIRGDGPLQGILVDA
GLDGTVRGYVTNPGVELPPNAKGKLDVGGAVGKGFLYVIRDMGYGYPYSSTVELVSGEIGEDVTHYLVTSEQTPSALALG
VFVGAQGVTASGGLLIQVLPKAAEDPALVELLESRLAHLQGFTPLLQAGKTLPDIFTDLLGDMGLKIFPQTQMVQFQCRC
STERVLGALKMLGQDELLDMIEKDDGAEATCDFCGEVYQVTSDQLGKLIDDLKTEAGA

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:
GO:0005737: 33 kDa chaperonin
GO:0006457: 33 kDa chaperonin
GO:0051082: 33 kDa chaperonin

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=283, Percent_Identity=26.1484098939929, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_ACAM1 (B0C4Q9)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001519260.1
- ProteinModelPortal:   B0C4Q9
- SMR:   B0C4Q9
- GeneID:   5683773
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_4974
- HOGENOM:   HBG286231
- OMA:   VMLGRAM
- ProtClustDB:   PRK00114
- BioCyc:   AMAR329726:AM1_4974-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 31602; Mature: 31470

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQLIRATAADDGIRAVGVITTRLTEDARQRHGLSYVATAALGRTMSAGLLLASSMKQA
CCCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
EARINLRIRGDGPLQGILVDAGLDGTVRGYVTNPGVELPPNAKGKLDVGGAVGKGFLYVI
CEEEEEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCEECCCCHHHHHHHHH
RDMGYGYPYSSTVELVSGEIGEDVTHYLVTSEQTPSALALGVFVGAQGVTASGGLLIQVL
HHHCCCCCCCCHHHHHCCHHCCHHHHHEEECCCCCCHHHHHHHHCCCCCCCCCCEEEEEC
PKAAEDPALVELLESRLAHLQGFTPLLQAGKTLPDIFTDLLGDMGLKIFPQTQMVQFQCR
CCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHCCCEEECCCCEEEEEEC
CSTERVLGALKMLGQDELLDMIEKDDGAEATCDFCGEVYQVTSDQLGKLIDDLKTEAGA
CCHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADQLIRATAADDGIRAVGVITTRLTEDARQRHGLSYVATAALGRTMSAGLLLASSMKQA
CCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
EARINLRIRGDGPLQGILVDAGLDGTVRGYVTNPGVELPPNAKGKLDVGGAVGKGFLYVI
CEEEEEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCEECCCCHHHHHHHHH
RDMGYGYPYSSTVELVSGEIGEDVTHYLVTSEQTPSALALGVFVGAQGVTASGGLLIQVL
HHHCCCCCCCCHHHHHCCHHCCHHHHHEEECCCCCCHHHHHHHHCCCCCCCCCCEEEEEC
PKAAEDPALVELLESRLAHLQGFTPLLQAGKTLPDIFTDLLGDMGLKIFPQTQMVQFQCR
CCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHCCCEEECCCCEEEEEEC
CSTERVLGALKMLGQDELLDMIEKDDGAEATCDFCGEVYQVTSDQLGKLIDDLKTEAGA
CCHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA