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The map label for this gene is trpB [H]

Identifier: 158337918

GI number: 158337918

Start: 4842508

End: 4843764

Strand: Reverse

Name: trpB [H]

Synonym: AM1_4805

Alternate gene names: 158337918

Gene position: 4843764-4842508 (Counterclockwise)

Preceding gene: 158337922

Following gene: 158337917

Centisome position: 74.48

GC content: 53.3

Gene sequence:

>1257_bases
GTGGCTGTTACTCCCCTATCCTCTGCTGACCAATCCTCTGGCGCACAACAATATCCTGATGCCTTGGGTCGCTTTGGTCC
CTACGGTGGGAAATATGTCCCCGAAACTCTGATGCCTGCCCTGGCAGAACTGGAATCTGCCCTCGCCCAGTACCGAAACG
ATCCAGAGTTTCAGGCAGAACTCAGCCAACTGCTCAAAGACTATGTAGGTCGGCCTAGCCCCCTGTATTTTGCCGAGCGG
CTAACCACCCACTATGCCCGTCCCGATGGCAGTGGTCCCCAGATCTATTTAAAGCGAGAAGACCTTAACCATACAGGAGC
CCATAAAATCAACAATGCCCTCGCTCAAGCCTTGCTCGCTAAGCGGATGGGCAAACAGCGAATTATTGCTGAAACGGGCG
CTGGACAGCATGGGGTGGCAACAGCAACTGTCTGTGCCCGCTTTGGCTTTGACTGTGTGATTTATATGGGGGTCCAGGAT
ATGGAACGTCAGGCCCTCAATGTATTTCGGATGCGGCTATTAGGGGCAGAAGTTCATCCGGTGGAAGCGGGAACAGGAAC
CCTTAAGGATGCCACCTCGGAAGCCATTCGCGACTGGGTGACTAACGTAGAAACCACCCACTATATTTTGGGTTCTGTGG
CTGGTCCCCACCCCTATCCAATGATGGTGCGAGATTTCCATGCCGTGATTGGCCAAGAGACTCGCCAGCAATGCCAAGAG
CAATGGAATGGTACCCCCGATATCTTGCTCGCCTGCGTGGGGGGTGGGTCAAATGCGATGGGTTTATTTCATGAGTTTGT
GCCTGATACTCAAATCCGCATGATTGGTGTGGAGGCCGCTGGCGCTGGCGTTAATACTGATAAACATGCAGCCACGCTCA
CCCAAGGGGAAGCTGGGGTGCTGCACGGGGCCATGAGTTATCTGCTACAAGATGAAGATGGTCAGGTGTTAGAGGCCCAT
TCTATTAGTGCGGGACTGGATTATCCTGGCGTGGGCCCTGAGCATAGTTTTCTTAAGGATAGTGGCCGCTGTGAATATTA
CAGCGTCACGGATACAGAGGCTGTTGCGGCCTTTCAGCGACTAACGGAACTGGAAGGGATTATTCCGGCCCTGGAAACGA
GTCATGCGATCGCATATCTGGAAACCCTCTGTCCCCAGCTAGAAGGCAGTCCCCGGATTGTTATTTCCTGTTCGGGTCGG
GGCGATAAAGATGTCCAAACCGTAGCTAAGTTTTTAGAGCAGCAATCTCCCCAGTAG

Upstream 100 bases:

>100_bases
AAACTTCCAAGTCGATAGGTCGACTACGCATGAAGAATCATCCAGCGACACACCATCTTTTTCTATAATGAGTGTCTGAT
CATCTGTTTGGGTATTCATC

Downstream 100 bases:

>100_bases
ACTGACCTGCAAGAGAAGCACCGATATTGCAACAACAAAAGTTAATAAAGGGTTAAAATCAGGTTGCGGTTCATTTAAGG
CTTCAACTCCATGCCCTTTG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MAVTPLSSADQSSGAQQYPDALGRFGPYGGKYVPETLMPALAELESALAQYRNDPEFQAELSQLLKDYVGRPSPLYFAER
LTTHYARPDGSGPQIYLKREDLNHTGAHKINNALAQALLAKRMGKQRIIAETGAGQHGVATATVCARFGFDCVIYMGVQD
MERQALNVFRMRLLGAEVHPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGQETRQQCQE
QWNGTPDILLACVGGGSNAMGLFHEFVPDTQIRMIGVEAAGAGVNTDKHAATLTQGEAGVLHGAMSYLLQDEDGQVLEAH
SISAGLDYPGVGPEHSFLKDSGRCEYYSVTDTEAVAAFQRLTELEGIIPALETSHAIAYLETLCPQLEGSPRIVISCSGR
GDKDVQTVAKFLEQQSPQ

Sequences:

>Translated_418_residues
MAVTPLSSADQSSGAQQYPDALGRFGPYGGKYVPETLMPALAELESALAQYRNDPEFQAELSQLLKDYVGRPSPLYFAER
LTTHYARPDGSGPQIYLKREDLNHTGAHKINNALAQALLAKRMGKQRIIAETGAGQHGVATATVCARFGFDCVIYMGVQD
MERQALNVFRMRLLGAEVHPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGQETRQQCQE
QWNGTPDILLACVGGGSNAMGLFHEFVPDTQIRMIGVEAAGAGVNTDKHAATLTQGEAGVLHGAMSYLLQDEDGQVLEAH
SISAGLDYPGVGPEHSFLKDSGRCEYYSVTDTEAVAAFQRLTELEGIIPALETSHAIAYLETLCPQLEGSPRIVISCSGR
GDKDVQTVAKFLEQQSPQ
>Mature_417_residues
AVTPLSSADQSSGAQQYPDALGRFGPYGGKYVPETLMPALAELESALAQYRNDPEFQAELSQLLKDYVGRPSPLYFAERL
TTHYARPDGSGPQIYLKREDLNHTGAHKINNALAQALLAKRMGKQRIIAETGAGQHGVATATVCARFGFDCVIYMGVQDM
ERQALNVFRMRLLGAEVHPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGQETRQQCQEQ
WNGTPDILLACVGGGSNAMGLFHEFVPDTQIRMIGVEAAGAGVNTDKHAATLTQGEAGVLHGAMSYLLQDEDGQVLEAHS
ISAGLDYPGVGPEHSFLKDSGRCEYYSVTDTEAVAAFQRLTELEGIIPALETSHAIAYLETLCPQLEGSPRIVISCSGRG
DKDVQTVAKFLEQQSPQ

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=390, Percent_Identity=53.3333333333333, Blast_Score=428, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321412, Length=396, Percent_Identity=56.8181818181818, Blast_Score=464, Evalue=1e-132,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 45224; Mature: 45093

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTPLSSADQSSGAQQYPDALGRFGPYGGKYVPETLMPALAELESALAQYRNDPEFQAE
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
LSQLLKDYVGRPSPLYFAERLTTHYARPDGSGPQIYLKREDLNHTGAHKINNALAQALLA
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
KRMGKQRIIAETGAGQHGVATATVCARFGFDCVIYMGVQDMERQALNVFRMRLLGAEVHP
HHHCCHHEEHCCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCC
VEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGQETRQQCQE
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHH
QWNGTPDILLACVGGGSNAMGLFHEFVPDTQIRMIGVEAAGAGVNTDKHAATLTQGEAGV
HHCCCHHHEEEEECCCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHEECCCCHHH
LHGAMSYLLQDEDGQVLEAHSISAGLDYPGVGPEHSFLKDSGRCEYYSVTDTEAVAAFQR
HHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCCEEEEECCCHHHHHHHHH
LTELEGIIPALETSHAIAYLETLCPQLEGSPRIVISCSGRGDKDVQTVAKFLEQQSPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVTPLSSADQSSGAQQYPDALGRFGPYGGKYVPETLMPALAELESALAQYRNDPEFQAE
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
LSQLLKDYVGRPSPLYFAERLTTHYARPDGSGPQIYLKREDLNHTGAHKINNALAQALLA
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
KRMGKQRIIAETGAGQHGVATATVCARFGFDCVIYMGVQDMERQALNVFRMRLLGAEVHP
HHHCCHHEEHCCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCC
VEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGQETRQQCQE
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHH
QWNGTPDILLACVGGGSNAMGLFHEFVPDTQIRMIGVEAAGAGVNTDKHAATLTQGEAGV
HHCCCHHHEEEEECCCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHEECCCCHHH
LHGAMSYLLQDEDGQVLEAHSISAGLDYPGVGPEHSFLKDSGRCEYYSVTDTEAVAAFQR
HHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCCEEEEECCCHHHHHHHHH
LTELEGIIPALETSHAIAYLETLCPQLEGSPRIVISCSGRGDKDVQTVAKFLEQQSPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]