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The map label for this gene is cobO [H]

Identifier: 158337805

GI number: 158337805

Start: 4725235

End: 4725879

Strand: Direct

Name: cobO [H]

Synonym: AM1_4691

Alternate gene names: 158337805

Gene position: 4725235-4725879 (Clockwise)

Preceding gene: 158337804

Following gene: 158337806

Centisome position: 72.65

GC content: 53.02

Gene sequence:

>645_bases
ATGACTCAATCGGCCTCTTCCACCTCACCATCAACTGACTCGCAACTCACTGCAGAGCAGCATCAGCAGAAAATGCAGCG
CCGCAAACAGGTGCAGGATCAGCGGGTCGCCGAGCGATCGCACGAGAAAGGCTTAGTCATTATCCATACGGGAAACGGTA
AAGGCAAAACCACTGCCGCCTTGGGTATGGTCATGAGATCCCTGGGACATGGGTATAAAGTCGCCATTGTTCAGTTCATC
AAAGGAGCATGGGAACCGGCTGAAAAAGCCGTCTTAGGAAACTGGCCCGATCAGCTTGTGTTTCATGCCATGGGCGAAGG
ATTTACCTGGGAGACTCAAGACCGCGAGCGCGACACCGCCAAAGCTCAAGCCGCCTGGGAGCAAGCCCTGGCTTATATTC
AGAATCCTGACTATCGTCTAGTGCTCTTGGATGAGGTCAATATTGCCCTTAAGCATGGCTATTTGGACGTCACCACCGTA
AACGCCGGATTGCAGTCCAAGCCTGCCGACACCCACGTCATCCTCACCGGGCGAGGAGCCCCCAAAGAATTAATCGATCA
GGCCGATTTAGTCACTGAGATGACCCTGGTCAAACATCCTTTCCGTGAACAAGGCGTGAAAGCCCAACCTGGTATCGAAT
TTTAG

Upstream 100 bases:

>100_bases
TGAAGTTGGGCATAGGTCAAGGCCTCTAGCTAACAAATGATCCCTTTGACCGGAAACCATTACTATTTTAAAGAGCCCAG
TCATTGTTACTGATATTCCT

Downstream 100 bases:

>100_bases
GAGGATCTTAATGGTACGGACAGTGGAACGGCCCACCCAATCGGTGGAGTTCGTCAAACAACCTCGTCCCTGGCGCAGCA
TCATTGCCGACGTCATCTTA

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MTQSASSTSPSTDSQLTAEQHQQKMQRRKQVQDQRVAERSHEKGLVIIHTGNGKGKTTAALGMVMRSLGHGYKVAIVQFI
KGAWEPAEKAVLGNWPDQLVFHAMGEGFTWETQDRERDTAKAQAAWEQALAYIQNPDYRLVLLDEVNIALKHGYLDVTTV
NAGLQSKPADTHVILTGRGAPKELIDQADLVTEMTLVKHPFREQGVKAQPGIEF

Sequences:

>Translated_214_residues
MTQSASSTSPSTDSQLTAEQHQQKMQRRKQVQDQRVAERSHEKGLVIIHTGNGKGKTTAALGMVMRSLGHGYKVAIVQFI
KGAWEPAEKAVLGNWPDQLVFHAMGEGFTWETQDRERDTAKAQAAWEQALAYIQNPDYRLVLLDEVNIALKHGYLDVTTV
NAGLQSKPADTHVILTGRGAPKELIDQADLVTEMTLVKHPFREQGVKAQPGIEF
>Mature_213_residues
TQSASSTSPSTDSQLTAEQHQQKMQRRKQVQDQRVAERSHEKGLVIIHTGNGKGKTTAALGMVMRSLGHGYKVAIVQFIK
GAWEPAEKAVLGNWPDQLVFHAMGEGFTWETQDRERDTAKAQAAWEQALAYIQNPDYRLVLLDEVNIALKHGYLDVTTVN
AGLQSKPADTHVILTGRGAPKELIDQADLVTEMTLVKHPFREQGVKAQPGIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=199, Percent_Identity=43.7185929648241, Blast_Score=172, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 23711; Mature: 23580

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSASSTSPSTDSQLTAEQHQQKMQRRKQVQDQRVAERSHEKGLVIIHTGNGKGKTTAA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
LGMVMRSLGHGYKVAIVQFIKGAWEPAEKAVLGNWPDQLVFHAMGEGFTWETQDRERDTA
HHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHH
KAQAAWEQALAYIQNPDYRLVLLDEVNIALKHGYLDVTTVNAGLQSKPADTHVILTGRGA
HHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCEEEEEEECCCCCCCCCCCEEEEECCCC
PKELIDQADLVTEMTLVKHPFREQGVKAQPGIEF
CHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
TQSASSTSPSTDSQLTAEQHQQKMQRRKQVQDQRVAERSHEKGLVIIHTGNGKGKTTAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
LGMVMRSLGHGYKVAIVQFIKGAWEPAEKAVLGNWPDQLVFHAMGEGFTWETQDRERDTA
HHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHH
KAQAAWEQALAYIQNPDYRLVLLDEVNIALKHGYLDVTTVNAGLQSKPADTHVILTGRGA
HHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCEEEEEEECCCCCCCCCCCEEEEECCCC
PKELIDQADLVTEMTLVKHPFREQGVKAQPGIEF
CHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]