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The map label for this gene is rnhA [H]

Identifier: 158337786

GI number: 158337786

Start: 4704418

End: 4705191

Strand: Reverse

Name: rnhA [H]

Synonym: AM1_4670

Alternate gene names: 158337786

Gene position: 4705191-4704418 (Counterclockwise)

Preceding gene: 158337788

Following gene: 158337782

Centisome position: 72.35

GC content: 48.71

Gene sequence:

>774_bases
ATGCCGGCTTTTTCTGATATTGACAGTATCTATACTGATGGCGCTTGTTCAGGGAATCCTGGTCCAGGCGGATGGGGCAG
TGTCATCTACTTCAAAGATGGATCCTGCCATGAAATTGGCGGGTTTGTGCCTCAAACGACGAATAACCGGATGGAATTGC
AGGCTGCGATCGCAATCTTGGAATTGTTGCAAGACCAACCGTTACCTAAGACCATTCCCCTCTATACTGACAGCGAATAC
GTCAAAAATGGCATTACTAAGTGGTTGGCAGGATGGAAACGTAAAGGCTGGAAAACAGCTAAAGGTAAAGCGGTTCTGAA
TCAAGATTTGTGGCAACAGCTCGATCAACTTAATGATGCGACCATAGACTGGCGATATATCCGCGCTCATGGAGGCCATG
AAGGCAATGAGCGATGTGATCAGATCGCTCGTGCTTTTTCCCAGTATCAAACCCCTGACCTTCACCAAATTACCCCCAGT
ACCATGCCAGACTCTCCCGAAGTGAATCAACATCCTCCCGATCATGCAGAACATCCTGCCAGTGAATCGAGGATCTCTCA
TCTGCAGGATTTAGTCGAAACGTTGGAAATTGCCGATCACATTGCGAAAGAGGGTTATCTAATCAGCAGTTCTGAATTAG
CAGATCTAATGGCGGTCCACGCCAACGCGGTCACTAGCAGAGGGGATGAATGGGTGTGGCGCAATTGGCTAATCTCCCGT
GTCCGTCGGGAAGGCAACCAGATTCTGTGGCAGTTAGAGCGTCTTAACTCCTAG

Upstream 100 bases:

>100_bases
GGGGGCATGGGGTGGATCTCCTCTGTTAAAAATCAGTTCTGTTATCCTTGCGACCAATCACCTAGGATAGGAGCGACGTT
TGCTTTGATGATGACGGACC

Downstream 100 bases:

>100_bases
GCATCGGCCCCAAAAAACAAGTGAGGCTGCATTTACAGCCTCACAAATCTATCAAGTCTAAAGAGGTGGGTTAGCAAGAC
CCACTTGAAACTTTAGCTTT

Product: ribonuclease HI

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MPAFSDIDSIYTDGACSGNPGPGGWGSVIYFKDGSCHEIGGFVPQTTNNRMELQAAIAILELLQDQPLPKTIPLYTDSEY
VKNGITKWLAGWKRKGWKTAKGKAVLNQDLWQQLDQLNDATIDWRYIRAHGGHEGNERCDQIARAFSQYQTPDLHQITPS
TMPDSPEVNQHPPDHAEHPASESRISHLQDLVETLEIADHIAKEGYLISSSELADLMAVHANAVTSRGDEWVWRNWLISR
VRREGNQILWQLERLNS

Sequences:

>Translated_257_residues
MPAFSDIDSIYTDGACSGNPGPGGWGSVIYFKDGSCHEIGGFVPQTTNNRMELQAAIAILELLQDQPLPKTIPLYTDSEY
VKNGITKWLAGWKRKGWKTAKGKAVLNQDLWQQLDQLNDATIDWRYIRAHGGHEGNERCDQIARAFSQYQTPDLHQITPS
TMPDSPEVNQHPPDHAEHPASESRISHLQDLVETLEIADHIAKEGYLISSSELADLMAVHANAVTSRGDEWVWRNWLISR
VRREGNQILWQLERLNS
>Mature_256_residues
PAFSDIDSIYTDGACSGNPGPGGWGSVIYFKDGSCHEIGGFVPQTTNNRMELQAAIAILELLQDQPLPKTIPLYTDSEYV
KNGITKWLAGWKRKGWKTAKGKAVLNQDLWQQLDQLNDATIDWRYIRAHGGHEGNERCDQIARAFSQYQTPDLHQITPST
MPDSPEVNQHPPDHAEHPASESRISHLQDLVETLEIADHIAKEGYLISSSELADLMAVHANAVTSRGDEWVWRNWLISRV
RREGNQILWQLERLNS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Homo sapiens, GI21359816, Length=144, Percent_Identity=37.5, Blast_Score=95, Evalue=5e-20,
Organism=Escherichia coli, GI1786408, Length=137, Percent_Identity=49.6350364963504, Blast_Score=138, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI115532542, Length=151, Percent_Identity=39.0728476821192, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17505482, Length=130, Percent_Identity=32.3076923076923, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17137476, Length=142, Percent_Identity=39.4366197183099, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI45552509, Length=142, Percent_Identity=39.4366197183099, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 28951; Mature: 28819

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAFSDIDSIYTDGACSGNPGPGGWGSVIYFKDGSCHEIGGFVPQTTNNRMELQAAIAIL
CCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCCCCCCCHHHHHHHHHHH
ELLQDQPLPKTIPLYTDSEYVKNGITKWLAGWKRKGWKTAKGKAVLNQDLWQQLDQLNDA
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
TIDWRYIRAHGGHEGNERCDQIARAFSQYQTPDLHQITPSTMPDSPEVNQHPPDHAEHPA
CCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SESRISHLQDLVETLEIADHIAKEGYLISSSELADLMAVHANAVTSRGDEWVWRNWLISR
HHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VRREGNQILWQLERLNS
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PAFSDIDSIYTDGACSGNPGPGGWGSVIYFKDGSCHEIGGFVPQTTNNRMELQAAIAIL
CCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCCCCCCCHHHHHHHHHHH
ELLQDQPLPKTIPLYTDSEYVKNGITKWLAGWKRKGWKTAKGKAVLNQDLWQQLDQLNDA
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
TIDWRYIRAHGGHEGNERCDQIARAFSQYQTPDLHQITPSTMPDSPEVNQHPPDHAEHPA
CCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SESRISHLQDLVETLEIADHIAKEGYLISSSELADLMAVHANAVTSRGDEWVWRNWLISR
HHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VRREGNQILWQLERLNS
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA