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The map label for this gene is murG [H]

Identifier: 158337764

GI number: 158337764

Start: 4681358

End: 4682458

Strand: Direct

Name: murG [H]

Synonym: AM1_4648

Alternate gene names: 158337764

Gene position: 4681358-4682458 (Clockwise)

Preceding gene: 158337759

Following gene: 158337769

Centisome position: 71.98

GC content: 52.68

Gene sequence:

>1101_bases
GTGAGCAATTCCGAATCGGTTGCCATAACAGAACAACCCCAGCGGTTCCTAATCGCTGCTAGCGGGACAGGCGGGCATTT
ATTCCCCGCGTTGGCCGTTGCAGAAGTCCTTGAAGCAGAGCAATTTCAACTGGAGTGGCTAGGGGTAAGCAATCGATTAG
AAACCCAGCTCGTTCCTAAAAAATATCCCTTACGGACGGTCCCTATTGAAGGACTCCAAACTCGGATAGGTCCAAAGACT
CCCATTCTCCTAGGAAAGTTAGCCGTGGCGGTTTGGCAAACCCGTCAACTTCTAAAGCGCGGCCAATTTAAGGGTGTGCT
CACTACGGGAGGCTATATCGCTGCCCCGGCCATTTTGGCCGCGTGGTCCCTAGGGTTACCGCGAGTGATTCATGAATCGA
ATGCCATTCCGGGGAAAGTGACGCGATGGCTCAGTTCGATCTGCACGGGGGTGGGGTTGGGATTAGAAGATGCCACAACA
TACTTGCCCAAAGACAAAACTGTAGTGGTGGGTACGCCTGTCCGTCCTGCGTTTTTGACTCCTTGTGAACTGGATTTACC
GATTCCGCCAGAGGCCACGCTGATTGTGGTGGCAGGCGGCAGCCAAGGCGCTGTCTCAGTCAACAAATTGGTACGAGCCT
GTGCACCAGCTTGGTTAGAGACGGGAGCTTGGATCGTCCATCTCACGGGAGCCCAAGATCCAGATGCTCAATCTTTTCAG
CATCCCCATTATTTGTCGATGCCGTTTTACGACAATATGGCTGGTTTATTGCAGCGGGCTAATTTAGCCATTAGTCGGGC
AGGTGCAGGGACCTTAAGCGAACTTGCGATCGCATCCACTCCTGCCCTCCTAATCCCTTACCCCTATGCCGCTGAGGACC
ATCAAGCGTTCAATGCGGCCGCTTTTGTTAAAGCGGGAGCTGCCGAGATGTATCGTCAGGATGAACTAACAGAAGAACAA
CTGAAACAGACCGTGCTCCAATGGATACAGGAACCTCAAGTCTTAGAGGAGATGGCTGTAAAGGCTTACAGCTTAGCAGT
CCCCAATAGCACAGAGCGCTTCGCCCAGCTCATTCTTGAGCAGATCGAAGCGTCTCCATGA

Upstream 100 bases:

>100_bases
GCCACGTTTCCCTGAAAGTAGCATCTCAATTCTAGATTAACTTTCCTATAGAAGGCGAAAACGCTAGAATTCTCAACTTC
CACCTACAAGGATAGCAACA

Downstream 100 bases:

>100_bases
AATAAATAGGTAACGTATCGCTAGAAGCCCAGCGTCTAGATCATTTTTAGGTGGGGATAAGCCGCAACTAAATCATCCGC
ACTGAGGGTGTCGGACTCCG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSNSESVAITEQPQRFLIAASGTGGHLFPALAVAEVLEAEQFQLEWLGVSNRLETQLVPKKYPLRTVPIEGLQTRIGPKT
PILLGKLAVAVWQTRQLLKRGQFKGVLTTGGYIAAPAILAAWSLGLPRVIHESNAIPGKVTRWLSSICTGVGLGLEDATT
YLPKDKTVVVGTPVRPAFLTPCELDLPIPPEATLIVVAGGSQGAVSVNKLVRACAPAWLETGAWIVHLTGAQDPDAQSFQ
HPHYLSMPFYDNMAGLLQRANLAISRAGAGTLSELAIASTPALLIPYPYAAEDHQAFNAAAFVKAGAAEMYRQDELTEEQ
LKQTVLQWIQEPQVLEEMAVKAYSLAVPNSTERFAQLILEQIEASP

Sequences:

>Translated_366_residues
MSNSESVAITEQPQRFLIAASGTGGHLFPALAVAEVLEAEQFQLEWLGVSNRLETQLVPKKYPLRTVPIEGLQTRIGPKT
PILLGKLAVAVWQTRQLLKRGQFKGVLTTGGYIAAPAILAAWSLGLPRVIHESNAIPGKVTRWLSSICTGVGLGLEDATT
YLPKDKTVVVGTPVRPAFLTPCELDLPIPPEATLIVVAGGSQGAVSVNKLVRACAPAWLETGAWIVHLTGAQDPDAQSFQ
HPHYLSMPFYDNMAGLLQRANLAISRAGAGTLSELAIASTPALLIPYPYAAEDHQAFNAAAFVKAGAAEMYRQDELTEEQ
LKQTVLQWIQEPQVLEEMAVKAYSLAVPNSTERFAQLILEQIEASP
>Mature_365_residues
SNSESVAITEQPQRFLIAASGTGGHLFPALAVAEVLEAEQFQLEWLGVSNRLETQLVPKKYPLRTVPIEGLQTRIGPKTP
ILLGKLAVAVWQTRQLLKRGQFKGVLTTGGYIAAPAILAAWSLGLPRVIHESNAIPGKVTRWLSSICTGVGLGLEDATTY
LPKDKTVVVGTPVRPAFLTPCELDLPIPPEATLIVVAGGSQGAVSVNKLVRACAPAWLETGAWIVHLTGAQDPDAQSFQH
PHYLSMPFYDNMAGLLQRANLAISRAGAGTLSELAIASTPALLIPYPYAAEDHQAFNAAAFVKAGAAEMYRQDELTEEQL
KQTVLQWIQEPQVLEEMAVKAYSLAVPNSTERFAQLILEQIEASP

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:
GO:0005886: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0005975: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0007047: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0007049: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0008360: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0009252: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0016020: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0016740: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0016757: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0016758: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0019277: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0030246: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0030259: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0050511: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0051301: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
GO:0051991: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=362, Percent_Identity=35.3591160220994, Blast_Score=177, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 39429; Mature: 39298

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSESVAITEQPQRFLIAASGTGGHLFPALAVAEVLEAEQFQLEWLGVSNRLETQLVPK
CCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHCCCCC
KYPLRTVPIEGLQTRIGPKTPILLGKLAVAVWQTRQLLKRGQFKGVLTTGGYIAAPAILA
CCCCEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
AWSLGLPRVIHESNAIPGKVTRWLSSICTGVGLGLEDATTYLPKDKTVVVGTPVRPAFLT
HHHCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCCCCCCC
PCELDLPIPPEATLIVVAGGSQGAVSVNKLVRACAPAWLETGAWIVHLTGAQDPDAQSFQ
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHCC
HPHYLSMPFYDNMAGLLQRANLAISRAGAGTLSELAIASTPALLIPYPYAAEDHQAFNAA
CCCEECCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHH
AFVKAGAAEMYRQDELTEEQLKQTVLQWIQEPQVLEEMAVKAYSLAVPNSTERFAQLILE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCHHHHHHHHHH
QIEASP
HHHCCC
>Mature Secondary Structure 
SNSESVAITEQPQRFLIAASGTGGHLFPALAVAEVLEAEQFQLEWLGVSNRLETQLVPK
CCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHCCCCC
KYPLRTVPIEGLQTRIGPKTPILLGKLAVAVWQTRQLLKRGQFKGVLTTGGYIAAPAILA
CCCCEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
AWSLGLPRVIHESNAIPGKVTRWLSSICTGVGLGLEDATTYLPKDKTVVVGTPVRPAFLT
HHHCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCCCCCCC
PCELDLPIPPEATLIVVAGGSQGAVSVNKLVRACAPAWLETGAWIVHLTGAQDPDAQSFQ
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHCC
HPHYLSMPFYDNMAGLLQRANLAISRAGAGTLSELAIASTPALLIPYPYAAEDHQAFNAA
CCCEECCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHH
AFVKAGAAEMYRQDELTEEQLKQTVLQWIQEPQVLEEMAVKAYSLAVPNSTERFAQLILE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCHHHHHHHHHH
QIEASP
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA