Click here to switch to the map view.

The map label for this gene is minD [H]

Identifier: 158337761

GI number: 158337761

Start: 4678555

End: 4679352

Strand: Reverse

Name: minD [H]

Synonym: AM1_4645

Alternate gene names: 158337761

Gene position: 4679352-4678555 (Counterclockwise)

Preceding gene: 158337762

Following gene: 158337760

Centisome position: 71.95

GC content: 49.0

Gene sequence:

>798_bases
ATGGGTCGAATTATAGTTATTACCTCTGGCAAAGGTGGGGTGGGCAAAACCACCTGTTCAGCCAATTTAGGAATGGCCTT
AGCAAGGCTAAACCATTCGGTCGCGCTCATAGACGCTGACTTTGGATTGCGCAACCTTGATTTGTTGCTGGGTTTAGAAA
ACCGTGTCGTGTATACAGCCCTGGAGGTCTTGGCTGGGCAATGTCGCTTAGAACAAGCCCTGGTTAAAGACAAGCGCCTC
CATGATTTGGTGCTTCTACCGGCAGCCCAAAATCGCAACAAAGATGCCGTCACGCCAGAGCAGATGAAGCAGCTCGCTTA
TGCGTTGACGAAAAAGTATGATTTTGTCTTGATCGACTGCCCGGCAGGGATTGAGATGGGGTTTCAGAATGCGATCGCAG
CTGCAGACGAAGCCTTAATTGTGACGACTCCTGAAATTTCCGCCGTTCGAGATGCCGACCGAGTGGTGGGGTTACTTGAA
GCGCACCATGTCAAAACCATCAATTTGATTGTGAACCGCATCCGACCCGCTATGGTTCAGGCCAATGACATGATGTCGGT
TCAGGATGTCCAAGAAATTCTAGCGATTCCTCTCATCGGCATGATTCCCGATGATGAGCAGGTGATTGTGGCGACCAACC
GTGGGGAACCCTTAGTACTATCAGAGAACTTTTCTCTTAGCGGTATGGCTCTGCAAAACATTGCTCAGCGGATTGAAGGA
AAGGACATCGATTTCTTAGATCTCAATGCCCCCTACGATACGCTTTTCTCGAGGGTTAAACGTTTCTTTAAACGGTAA

Upstream 100 bases:

>100_bases
AGCAAAAATATGATCCAACCCTAGCGAAATCACAAAATTGATATACACTATAAATCATTTGTTTGGCTGAGTTGACGAAA
GTTGTAACGCTCTCTGTTAT

Downstream 100 bases:

>100_bases
TTCTTTGCATATCCTCCAGCACATCAGCCAAGCTACACGTCATACTGTAGCCATTACCTCTGACTGTGGACGTTCACGCT
TACGTTGAAATTCTATGATT

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MGRIIVITSGKGGVGKTTCSANLGMALARLNHSVALIDADFGLRNLDLLLGLENRVVYTALEVLAGQCRLEQALVKDKRL
HDLVLLPAAQNRNKDAVTPEQMKQLAYALTKKYDFVLIDCPAGIEMGFQNAIAAADEALIVTTPEISAVRDADRVVGLLE
AHHVKTINLIVNRIRPAMVQANDMMSVQDVQEILAIPLIGMIPDDEQVIVATNRGEPLVLSENFSLSGMALQNIAQRIEG
KDIDFLDLNAPYDTLFSRVKRFFKR

Sequences:

>Translated_265_residues
MGRIIVITSGKGGVGKTTCSANLGMALARLNHSVALIDADFGLRNLDLLLGLENRVVYTALEVLAGQCRLEQALVKDKRL
HDLVLLPAAQNRNKDAVTPEQMKQLAYALTKKYDFVLIDCPAGIEMGFQNAIAAADEALIVTTPEISAVRDADRVVGLLE
AHHVKTINLIVNRIRPAMVQANDMMSVQDVQEILAIPLIGMIPDDEQVIVATNRGEPLVLSENFSLSGMALQNIAQRIEG
KDIDFLDLNAPYDTLFSRVKRFFKR
>Mature_264_residues
GRIIVITSGKGGVGKTTCSANLGMALARLNHSVALIDADFGLRNLDLLLGLENRVVYTALEVLAGQCRLEQALVKDKRLH
DLVLLPAAQNRNKDAVTPEQMKQLAYALTKKYDFVLIDCPAGIEMGFQNAIAAADEALIVTTPEISAVRDADRVVGLLEA
HHVKTINLIVNRIRPAMVQANDMMSVQDVQEILAIPLIGMIPDDEQVIVATNRGEPLVLSENFSLSGMALQNIAQRIEGK
DIDFLDLNAPYDTLFSRVKRFFKR

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:
GO:0000918: Septum site-determining protein MinD
GO:0006200: Septum site-determining protein MinD
GO:0016887: Septum site-determining protein MinD

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=259, Percent_Identity=23.5521235521236, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787423, Length=274, Percent_Identity=43.4306569343066, Blast_Score=216, Evalue=1e-57,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29059; Mature: 28928

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRIIVITSGKGGVGKTTCSANLGMALARLNHSVALIDADFGLRNLDLLLGLENRVVYTA
CCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCHHHHHH
LEVLAGQCRLEQALVKDKRLHDLVLLPAAQNRNKDAVTPEQMKQLAYALTKKYDFVLIDC
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEC
PAGIEMGFQNAIAAADEALIVTTPEISAVRDADRVVGLLEAHHVKTINLIVNRIRPAMVQ
CCCCCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANDMMSVQDVQEILAIPLIGMIPDDEQVIVATNRGEPLVLSENFSLSGMALQNIAQRIEG
CCCCCCHHHHHHHHHCCEEECCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCC
KDIDFLDLNAPYDTLFSRVKRFFKR
CCCCEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
GRIIVITSGKGGVGKTTCSANLGMALARLNHSVALIDADFGLRNLDLLLGLENRVVYTA
CEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCHHHHHH
LEVLAGQCRLEQALVKDKRLHDLVLLPAAQNRNKDAVTPEQMKQLAYALTKKYDFVLIDC
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEC
PAGIEMGFQNAIAAADEALIVTTPEISAVRDADRVVGLLEAHHVKTINLIVNRIRPAMVQ
CCCCCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANDMMSVQDVQEILAIPLIGMIPDDEQVIVATNRGEPLVLSENFSLSGMALQNIAQRIEG
CCCCCCHHHHHHHHHCCEEECCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCC
KDIDFLDLNAPYDTLFSRVKRFFKR
CCCCEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]