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The map label for this gene is petH [H]

Identifier: 158337746

GI number: 158337746

Start: 4663471

End: 4664724

Strand: Reverse

Name: petH [H]

Synonym: AM1_4630

Alternate gene names: 158337746

Gene position: 4664724-4663471 (Counterclockwise)

Preceding gene: 158337747

Following gene: 158337745

Centisome position: 71.72

GC content: 47.53

Gene sequence:

>1254_bases
ATGGCTATATTGGCTGAATTTAATCAGACTCTGAAAAAGTATGGTGTTTCAAATGCAAGGGTGGTTGAATTTACCCTCAG
TGATCAAGAGATGCCGGAAATGGAAGGTTTGTCCTGCAACTTTTCCTGTTGGGTATCCCCTAGCAATTTGACCTGTGGTA
TCAAATGCGAATTTGAAGCTTCCGGCACCACTGGAGCGAAACCGGCAGCTATCGCTACACCAACTGCTAAAAAAGCTGAG
AAGGCTAAGCTTTTAGCGGCAGCGGCGGCAGCTCCCACCAAATCTGCTGCACCTGCAGCGAAAAAAGCCAAGAAAAAGTC
GGATGTTCCGATTAATATCTACCGTCCCAATAAACCCTTTGTGGGCAAGTGTATCTCCAATGAAGAGCTGGTGGGGCCTG
GCGGTATCGGTACCTGTCGCCATTTGATTTTCGATATTTCTGCTGGTGATTTGAAATATGTCGAAGGCCAGAGTATTGGC
ATCATTGCAGACGGCACGGATGATAAAGGCAAACCCCATAAGATTCGTCTTTACTCCATTGCGTCAGCCCACCGTGGTGA
TTATCTAGATGATAAAACCGTCTCTCTCTGTGTCCGTCAATTAGAGTATCCCGATCCAGACACGGGTAAAACGGTCTATG
GCGTTTGCTCTAGCTTCCTGTGTAACCTCAAGCCTGGAGATGATGTCAAAATCACAGGGCCTGTGGGTAAAGAAATGCTC
TTACCTGATGATCCCAACGCCAACATCATTATGCTGGGGACCGGGACTGGAATTGCTCCTTTCCGCTCTTTCCTCTGGCA
CTTGTTCAAAGAGAATGAAGATGCCAATGCCAATCCCTTCTGGCTACCCAAGTTATTGGGATGGGTCAAGCCCAGCGATA
AGCCCAAGTTTAACGGTAAGACCTGGTTAATTTTCGGCGTAGCTACTACCCCCAATATCCTGTACAACAAGGATTTAGAA
GACCTACAGCGTCGCTATCCCGACAACTTCCGCTTAACGAAAGCCATTAGTCGCGAACAGAAGAATCCTGAAGGTGGACG
GATGTATATCCAACACCGGGTTGCGGAGCATGCGGAAGAACTCTGGCAGATGATCCAGCAGGAAAACACCCACACCTATA
TTTGTGGTTTGAAAGGGATGGAAAAAGGCATTGATGAAGCCCTAAGCGCCGTTGCCAGCAAAGATGGCGTTAACTGGAGC
GACTATCAACGGGAAATGAAAAAAGCTCATCGTTGGCATGTAGAAACCTACTAA

Upstream 100 bases:

>100_bases
ATCGCAAAAGCAGCCAATACCCCAGTTGAATGATGAGTGAGCATTAAGAATGGATTATGAAAGCATGAAAGGGTTAGCCG
GAGAGGTTGAACCCAAGTTA

Downstream 100 bases:

>100_bases
GCCACCATTCTTTGACGAGCCTCATTCTTGAAAATTTAACTCTCTGAAGCACTCCAGTTCTCAATGAACTGGAGTTTTTT
TGATCATTTAAATTGGAGAA

Product: ferredoxin-NADP reductase PetH

Products: NA

Alternate protein names: FNR [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MAILAEFNQTLKKYGVSNARVVEFTLSDQEMPEMEGLSCNFSCWVSPSNLTCGIKCEFEASGTTGAKPAAIATPTAKKAE
KAKLLAAAAAAPTKSAAPAAKKAKKKSDVPINIYRPNKPFVGKCISNEELVGPGGIGTCRHLIFDISAGDLKYVEGQSIG
IIADGTDDKGKPHKIRLYSIASAHRGDYLDDKTVSLCVRQLEYPDPDTGKTVYGVCSSFLCNLKPGDDVKITGPVGKEML
LPDDPNANIIMLGTGTGIAPFRSFLWHLFKENEDANANPFWLPKLLGWVKPSDKPKFNGKTWLIFGVATTPNILYNKDLE
DLQRRYPDNFRLTKAISREQKNPEGGRMYIQHRVAEHAEELWQMIQQENTHTYICGLKGMEKGIDEALSAVASKDGVNWS
DYQREMKKAHRWHVETY

Sequences:

>Translated_417_residues
MAILAEFNQTLKKYGVSNARVVEFTLSDQEMPEMEGLSCNFSCWVSPSNLTCGIKCEFEASGTTGAKPAAIATPTAKKAE
KAKLLAAAAAAPTKSAAPAAKKAKKKSDVPINIYRPNKPFVGKCISNEELVGPGGIGTCRHLIFDISAGDLKYVEGQSIG
IIADGTDDKGKPHKIRLYSIASAHRGDYLDDKTVSLCVRQLEYPDPDTGKTVYGVCSSFLCNLKPGDDVKITGPVGKEML
LPDDPNANIIMLGTGTGIAPFRSFLWHLFKENEDANANPFWLPKLLGWVKPSDKPKFNGKTWLIFGVATTPNILYNKDLE
DLQRRYPDNFRLTKAISREQKNPEGGRMYIQHRVAEHAEELWQMIQQENTHTYICGLKGMEKGIDEALSAVASKDGVNWS
DYQREMKKAHRWHVETY
>Mature_416_residues
AILAEFNQTLKKYGVSNARVVEFTLSDQEMPEMEGLSCNFSCWVSPSNLTCGIKCEFEASGTTGAKPAAIATPTAKKAEK
AKLLAAAAAAPTKSAAPAAKKAKKKSDVPINIYRPNKPFVGKCISNEELVGPGGIGTCRHLIFDISAGDLKYVEGQSIGI
IADGTDDKGKPHKIRLYSIASAHRGDYLDDKTVSLCVRQLEYPDPDTGKTVYGVCSSFLCNLKPGDDVKITGPVGKEMLL
PDDPNANIIMLGTGTGIAPFRSFLWHLFKENEDANANPFWLPKLLGWVKPSDKPKFNGKTWLIFGVATTPNILYNKDLED
LQRRYPDNFRLTKAISREQKNPEGGRMYIQHRVAEHAEELWQMIQQENTHTYICGLKGMEKGIDEALSAVASKDGVNWSD
YQREMKKAHRWHVETY

Specific function: Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. The Flavo-Protein Component Catalyzes The Electron Flow From Nadph -> FAD -> Fmn To The Hemoprotein Compo

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=May be bound to the thylakoid membrane or anchored to the thylakoid-bound phycobilisomes [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI40254422, Length=227, Percent_Identity=29.5154185022026, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI24041029, Length=251, Percent_Identity=27.0916334661355, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321832, Length=171, Percent_Identity=28.0701754385965, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI78706872, Length=251, Percent_Identity=29.4820717131474, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24583543, Length=218, Percent_Identity=32.1100917431193, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI78706876, Length=218, Percent_Identity=32.1100917431193, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012146
- InterPro:   IPR015701
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR008213
- InterPro:   IPR017938 [H]

Pfam domain/function: PF01383 CpcD; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 46061; Mature: 45930

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILAEFNQTLKKYGVSNARVVEFTLSDQEMPEMEGLSCNFSCWVSPSNLTCGIKCEFEA
CEEHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEEC
SGTTGAKPAAIATPTAKKAEKAKLLAAAAAAPTKSAAPAAKKAKKKSDVPINIYRPNKPF
CCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEECCCCCC
VGKCISNEELVGPGGIGTCRHLIFDISAGDLKYVEGQSIGIIADGTDDKGKPHKIRLYSI
EEEECCCCCEECCCCCHHHHHEEEECCCCCEEEECCCEEEEEECCCCCCCCCCEEEEEEE
ASAHRGDYLDDKTVSLCVRQLEYPDPDTGKTVYGVCSSFLCNLKPGDDVKITGPVGKEML
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCC
LPDDPNANIIMLGTGTGIAPFRSFLWHLFKENEDANANPFWLPKLLGWVKPSDKPKFNGK
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHCCCCCCCCCCCC
TWLIFGVATTPNILYNKDLEDLQRRYPDNFRLTKAISREQKNPEGGRMYIQHRVAEHAEE
EEEEEEECCCCCEEECCCHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHH
LWQMIQQENTHTYICGLKGMEKGIDEALSAVASKDGVNWSDYQREMKKAHRWHVETY
HHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AILAEFNQTLKKYGVSNARVVEFTLSDQEMPEMEGLSCNFSCWVSPSNLTCGIKCEFEA
EEHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEEC
SGTTGAKPAAIATPTAKKAEKAKLLAAAAAAPTKSAAPAAKKAKKKSDVPINIYRPNKPF
CCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEECCCCCC
VGKCISNEELVGPGGIGTCRHLIFDISAGDLKYVEGQSIGIIADGTDDKGKPHKIRLYSI
EEEECCCCCEECCCCCHHHHHEEEECCCCCEEEECCCEEEEEECCCCCCCCCCEEEEEEE
ASAHRGDYLDDKTVSLCVRQLEYPDPDTGKTVYGVCSSFLCNLKPGDDVKITGPVGKEML
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCC
LPDDPNANIIMLGTGTGIAPFRSFLWHLFKENEDANANPFWLPKLLGWVKPSDKPKFNGK
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHCCCCCCCCCCCC
TWLIFGVATTPNILYNKDLEDLQRRYPDNFRLTKAISREQKNPEGGRMYIQHRVAEHAEE
EEEEEEECCCCCEEECCCHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHH
LWQMIQQENTHTYICGLKGMEKGIDEALSAVASKDGVNWSDYQREMKKAHRWHVETY
HHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8343609; 2124680; 3124746; 8890910; 9922134; 10651039; 11053838 [H]