Click here to switch to the map view.

The map label for this gene is kptA

Identifier: 158337724

GI number: 158337724

Start: 4639181

End: 4639726

Strand: Direct

Name: kptA

Synonym: AM1_4608

Alternate gene names: 158337724

Gene position: 4639181-4639726 (Clockwise)

Preceding gene: 158337723

Following gene: 158337727

Centisome position: 71.33

GC content: 42.31

Gene sequence:

>546_bases
ATGGATCAACAGTTAAAAGCTGTTAGTAAGTTTCTCAGCTATATTCTTCGACATCGACCTGAGGCGATTAGTTTAGAACT
GAATGCAGGTGGCTGGGCAGCTATTTCTGAATTAATTCAATGCGCTAGCAAGCATGACCATTTCTTATCTGAAGAAATTA
TCAAAGAAGTAGTTGTTTCTAATGACAAGAAGCGGTTTAAATTAAGTGAAGATGGCCAATATATTCGAGCTAACCAAGGA
CATTCCATTCGGGTTGACTTGGATTTATTGCCTTTGACACCTCCTGATGTTTTATTCCATGGAACAGCCACACGGTTTTT
AGCGTCTATCATGGCGAAGGGCCTACTCCCTTCAGGACGTCAACATGTCCATCTTTCAGCGTCATACGAAACTGCGATCG
CAGTGGGCAGACGGCATGGCAAACCCACGGTATTGGAAATTAATGCCCAAAAAATGCAAGGTGACGGCTATCTGTTTTAT
CGTTCTGAAAATGGTGTTTGGCTCACCGATCATGTGCCTGCTCAGTATTTCGTAGAAGTAGAATAA

Upstream 100 bases:

>100_bases
CCTGTCCCTACCCCCCAATTATATAAGGAGCTGCCCTTTGAAATTGTTCAGGCAGGACACCCATGGCCCACAATAATATT
CAAAATTACATTCTTAAAAT

Downstream 100 bases:

>100_bases
AATTAGCTCAATCTATAACCCCTAGGCTCTATTGCGACAGACAAATAAAAACCATACAATAGAGATGTTTGATAATAAAA
AGTGAAAGGGAATAATTGGC

Product: RNA 2'-phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MDQQLKAVSKFLSYILRHRPEAISLELNAGGWAAISELIQCASKHDHFLSEEIIKEVVVSNDKKRFKLSEDGQYIRANQG
HSIRVDLDLLPLTPPDVLFHGTATRFLASIMAKGLLPSGRQHVHLSASYETAIAVGRRHGKPTVLEINAQKMQGDGYLFY
RSENGVWLTDHVPAQYFVEVE

Sequences:

>Translated_181_residues
MDQQLKAVSKFLSYILRHRPEAISLELNAGGWAAISELIQCASKHDHFLSEEIIKEVVVSNDKKRFKLSEDGQYIRANQG
HSIRVDLDLLPLTPPDVLFHGTATRFLASIMAKGLLPSGRQHVHLSASYETAIAVGRRHGKPTVLEINAQKMQGDGYLFY
RSENGVWLTDHVPAQYFVEVE
>Mature_181_residues
MDQQLKAVSKFLSYILRHRPEAISLELNAGGWAAISELIQCASKHDHFLSEEIIKEVVVSNDKKRFKLSEDGQYIRANQG
HSIRVDLDLLPLTPPDVLFHGTATRFLASIMAKGLLPSGRQHVHLSASYETAIAVGRRHGKPTVLEINAQKMQGDGYLFY
RSENGVWLTDHVPAQYFVEVE

Specific function: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP- ribosy

COG id: COG1859

COG function: function code J; RNA:NAD 2'-phosphotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kptA/TPT1 family

Homologues:

Organism=Homo sapiens, GI238550157, Length=173, Percent_Identity=38.728323699422, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI238550153, Length=173, Percent_Identity=38.728323699422, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI238550169, Length=174, Percent_Identity=39.0804597701149, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI238550149, Length=175, Percent_Identity=38.2857142857143, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI13899325, Length=154, Percent_Identity=37.6623376623377, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI238550165, Length=128, Percent_Identity=41.40625, Blast_Score=77, Evalue=7e-15,
Organism=Escherichia coli, GI87082424, Length=177, Percent_Identity=47.4576271186441, Blast_Score=170, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6324470, Length=194, Percent_Identity=29.8969072164948, Blast_Score=75, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28575019, Length=185, Percent_Identity=31.3513513513514, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KPTA_ACAM1 (B0C090)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001518900.1
- ProteinModelPortal:   B0C090
- SMR:   B0C090
- GeneID:   5683410
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_4608
- HOGENOM:   HBG332834
- OMA:   CEIAVFI
- BioCyc:   AMAR329726:AM1_4608-MONOMER
- HAMAP:   MF_00299
- InterPro:   IPR022928
- InterPro:   IPR002745

Pfam domain/function: PF01885 PTS_2-RNA

EC number: 2.7.-.- [C]

Molecular weight: Translated: 20336; Mature: 20336

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQQLKAVSKFLSYILRHRPEAISLELNAGGWAAISELIQCASKHDHFLSEEIIKEVVVS
CCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
NDKKRFKLSEDGQYIRANQGHSIRVDLDLLPLTPPDVLFHGTATRFLASIMAKGLLPSGR
CCCCEEEECCCCCEEEECCCCEEEEEEEEECCCCCCEEECCHHHHHHHHHHHHCCCCCCC
QHVHLSASYETAIAVGRRHGKPTVLEINAQKMQGDGYLFYRSENGVWLTDHVPAQYFVEV
CEEEEECCCHHHHHHHHCCCCCEEEEEEHHEECCCEEEEEECCCCEEEECCCCCEEEEEE
E
C
>Mature Secondary Structure
MDQQLKAVSKFLSYILRHRPEAISLELNAGGWAAISELIQCASKHDHFLSEEIIKEVVVS
CCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
NDKKRFKLSEDGQYIRANQGHSIRVDLDLLPLTPPDVLFHGTATRFLASIMAKGLLPSGR
CCCCEEEECCCCCEEEECCCCEEEEEEEEECCCCCCEEECCHHHHHHHHHHHHCCCCCCC
QHVHLSASYETAIAVGRRHGKPTVLEINAQKMQGDGYLFYRSENGVWLTDHVPAQYFVEV
CEEEEECCCHHHHHHHHCCCCCEEEEEEHHEECCCEEEEEECCCCEEEECCCCCEEEEEE
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA