BacMap

Definition	Acaryochloris marina MBIC11017 chromosome, complete genome.
Accession	NC_009925
Length	6,503,724

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The map label for this gene is rot [H]

Identifier: 158337722

GI number: 158337722

Start: 4637812

End: 4638234

Strand: Reverse

Name: rot [H]

Synonym: AM1_4606

Alternate gene names: 158337722

Gene position: 4638234-4637812 (Counterclockwise)

Preceding gene: 158337725

Following gene: 158337712

Centisome position: 71.32

GC content: 44.44

Gene sequence:

>423_bases
ATGACCAAAGCCATAATGGAAACAGACAAAGGTACGATTAATCTTGATTTATTTGATCAGGACGCCCCTAACACCGTCAA
AAATTTCGTTGACTTAGCCAATAAAGGGTTTTATGACGGCTTATCTTTTCATCGTGTCATTCCTAATTTTATGATCCAAG
GGGGTTGCCCAAAAGGAACAGGAACGGGTGGCCCTGGCTACACCATTAAGTGCGAAATTAATAACAACAAACACCAAGCT
GGAACTCTATCCATGGCCCATGCAGGTCGGGATACAGGCGGCAGCCAATTCTTTATTTGCCATGCCCCTCAACCTCATTT
GGATGGCGTGCATACGACTTTCGGGCAAACCCAAGATATGGATGTAGTGAATGCCATTCGTCAGGGGGACAAAATCCTAT
CGGTTAAAGTCTCTGCTGAATAA

Upstream 100 bases:

>100_bases
AGTAATGAAAAAGGGATTAACGTAAAAATTGAATTGCAATCCCCTTGGTCCCAAGATAGGATGCCAAAGTTGCAGACAAT
ATCAAAAAGTTAGGATTACC

Downstream 100 bases:

>100_bases
GCTGAAAGGCGTGGATTCTGCTAATTGTTAATGACTGCACCTGGTGCAATCTGCTCTAGAGTCAAGTTAGGACACTCCAC
GCCCGACGCTTTTTGTAAGG

Product: cyclophilin-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MTKAIMETDKGTINLDLFDQDAPNTVKNFVDLANKGFYDGLSFHRVIPNFMIQGGCPKGTGTGGPGYTIKCEINNNKHQA
GTLSMAHAGRDTGGSQFFICHAPQPHLDGVHTTFGQTQDMDVVNAIRQGDKILSVKVSAE

Sequences:

>Translated_140_residues
MTKAIMETDKGTINLDLFDQDAPNTVKNFVDLANKGFYDGLSFHRVIPNFMIQGGCPKGTGTGGPGYTIKCEINNNKHQA
GTLSMAHAGRDTGGSQFFICHAPQPHLDGVHTTFGQTQDMDVVNAIRQGDKILSVKVSAE
>Mature_139_residues
TKAIMETDKGTINLDLFDQDAPNTVKNFVDLANKGFYDGLSFHRVIPNFMIQGGCPKGTGTGGPGYTIKCEINNNKHQAG
TLSMAHAGRDTGGSQFFICHAPQPHLDGVHTTFGQTQDMDVVNAIRQGDKILSVKVSAE

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706339, Length=128, Percent_Identity=47.65625, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI24308049, Length=129, Percent_Identity=46.5116279069767, Blast_Score=103, Evalue=6e-23,
Organism=Homo sapiens, GI64276486, Length=130, Percent_Identity=36.9230769230769, Blast_Score=94, Evalue=5e-20,
Organism=Homo sapiens, GI19557636, Length=119, Percent_Identity=42.8571428571429, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI4505991, Length=132, Percent_Identity=48.4848484848485, Blast_Score=87, Evalue=3e-18,
Organism=Homo sapiens, GI10863927, Length=127, Percent_Identity=45.6692913385827, Blast_Score=87, Evalue=3e-18,
Organism=Homo sapiens, GI4758950, Length=133, Percent_Identity=45.1127819548872, Blast_Score=87, Evalue=4e-18,
Organism=Homo sapiens, GI6631100, Length=121, Percent_Identity=47.1074380165289, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI4826932, Length=123, Percent_Identity=47.1544715447154, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI256017253, Length=125, Percent_Identity=45.6, Blast_Score=83, Evalue=6e-17,
Organism=Homo sapiens, GI221139811, Length=125, Percent_Identity=45.6, Blast_Score=83, Evalue=6e-17,
Organism=Homo sapiens, GI256017251, Length=125, Percent_Identity=45.6, Blast_Score=83, Evalue=6e-17,
Organism=Homo sapiens, GI310127646, Length=135, Percent_Identity=40.7407407407407, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI310114371, Length=135, Percent_Identity=40.7407407407407, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI310119221, Length=135, Percent_Identity=40.7407407407407, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI178057341, Length=128, Percent_Identity=43.75, Blast_Score=80, Evalue=5e-16,
Organism=Homo sapiens, GI209417936, Length=127, Percent_Identity=43.3070866141732, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI30102944, Length=127, Percent_Identity=43.3070866141732, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI219842199, Length=127, Percent_Identity=43.3070866141732, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI5031987, Length=127, Percent_Identity=44.8818897637795, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI310129267, Length=134, Percent_Identity=41.7910447761194, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI310120620, Length=134, Percent_Identity=41.7910447761194, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI310110104, Length=134, Percent_Identity=41.7910447761194, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI20911035, Length=138, Percent_Identity=34.0579710144928, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI42560244, Length=129, Percent_Identity=41.0852713178295, Blast_Score=74, Evalue=3e-14,
Organism=Homo sapiens, GI150418007, Length=125, Percent_Identity=44, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI169164185, Length=126, Percent_Identity=40.4761904761905, Blast_Score=73, Evalue=9e-14,
Organism=Homo sapiens, GI169163623, Length=126, Percent_Identity=40.4761904761905, Blast_Score=73, Evalue=9e-14,
Organism=Homo sapiens, GI169163387, Length=126, Percent_Identity=40.4761904761905, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI22547212, Length=127, Percent_Identity=44.0944881889764, Blast_Score=70, Evalue=6e-13,
Organism=Homo sapiens, GI7657473, Length=127, Percent_Identity=44.0944881889764, Blast_Score=70, Evalue=6e-13,
Organism=Homo sapiens, GI45439316, Length=130, Percent_Identity=40.7692307692308, Blast_Score=70, Evalue=8e-13,
Organism=Homo sapiens, GI22547215, Length=127, Percent_Identity=44.0944881889764, Blast_Score=70, Evalue=8e-13,
Organism=Homo sapiens, GI5174637, Length=131, Percent_Identity=42.7480916030534, Blast_Score=70, Evalue=8e-13,
Organism=Homo sapiens, GI303305009, Length=125, Percent_Identity=42.4, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI169214050, Length=126, Percent_Identity=40.4761904761905, Blast_Score=66, Evalue=9e-12,
Organism=Homo sapiens, GI310114540, Length=123, Percent_Identity=39.0243902439024, Blast_Score=66, Evalue=1e-11,
Organism=Homo sapiens, GI310127745, Length=123, Percent_Identity=39.0243902439024, Blast_Score=66, Evalue=1e-11,
Organism=Homo sapiens, GI310119290, Length=123, Percent_Identity=39.0243902439024, Blast_Score=66, Evalue=1e-11,
Organism=Homo sapiens, GI239751853, Length=126, Percent_Identity=40.4761904761905, Blast_Score=65, Evalue=1e-11,
Organism=Homo sapiens, GI113428306, Length=126, Percent_Identity=40.4761904761905, Blast_Score=65, Evalue=1e-11,
Organism=Homo sapiens, GI310132444, Length=127, Percent_Identity=39.3700787401575, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI310113152, Length=127, Percent_Identity=39.3700787401575, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI5454154, Length=122, Percent_Identity=38.5245901639344, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1789763, Length=134, Percent_Identity=41.7910447761194, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1786736, Length=132, Percent_Identity=38.6363636363636, Blast_Score=67, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17539496, Length=118, Percent_Identity=51.6949152542373, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17552780, Length=125, Percent_Identity=51.2, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17506307, Length=131, Percent_Identity=48.0916030534351, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17506311, Length=133, Percent_Identity=45.1127819548872, Blast_Score=96, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71997782, Length=132, Percent_Identity=39.3939393939394, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17532641, Length=114, Percent_Identity=44.7368421052632, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565860, Length=141, Percent_Identity=43.2624113475177, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559074, Length=134, Percent_Identity=41.7910447761194, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71980590, Length=137, Percent_Identity=37.2262773722628, Blast_Score=82, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71980594, Length=137, Percent_Identity=37.2262773722628, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17539498, Length=127, Percent_Identity=42.5196850393701, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17552782, Length=134, Percent_Identity=40.2985074626866, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17566266, Length=133, Percent_Identity=39.8496240601504, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17551284, Length=131, Percent_Identity=42.7480916030534, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17551282, Length=131, Percent_Identity=42.7480916030534, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17552784, Length=123, Percent_Identity=39.0243902439024, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532643, Length=123, Percent_Identity=41.4634146341463, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32563659, Length=128, Percent_Identity=32.03125, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323562, Length=134, Percent_Identity=47.7611940298507, Blast_Score=95, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321848, Length=133, Percent_Identity=48.1203007518797, Blast_Score=89, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320510, Length=128, Percent_Identity=46.09375, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320359, Length=127, Percent_Identity=44.8818897637795, Blast_Score=84, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6323246, Length=125, Percent_Identity=41.6, Blast_Score=70, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17986117, Length=127, Percent_Identity=48.0314960629921, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19922376, Length=116, Percent_Identity=42.2413793103448, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357249, Length=136, Percent_Identity=35.2941176470588, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI20130249, Length=126, Percent_Identity=46.8253968253968, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24650807, Length=122, Percent_Identity=44.2622950819672, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI19922912, Length=125, Percent_Identity=48, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45549139, Length=125, Percent_Identity=45.6, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24664125, Length=126, Percent_Identity=44.4444444444444, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357783, Length=126, Percent_Identity=44.4444444444444, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17647301, Length=115, Percent_Identity=46.0869565217391, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24586038, Length=129, Percent_Identity=40.3100775193798, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24652460, Length=119, Percent_Identity=36.9747899159664, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17136360, Length=131, Percent_Identity=36.6412213740458, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15082; Mature: 14951

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKAIMETDKGTINLDLFDQDAPNTVKNFVDLANKGFYDGLSFHRVIPNFMIQGGCPKGT
CCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHEEECCCCCCC
GTGGPGYTIKCEINNNKHQAGTLSMAHAGRDTGGSQFFICHAPQPHLDGVHTTFGQTQDM
CCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCH
DVVNAIRQGDKILSVKVSAE
HHHHHHHCCCEEEEEEEECC
>Mature Secondary Structure 
TKAIMETDKGTINLDLFDQDAPNTVKNFVDLANKGFYDGLSFHRVIPNFMIQGGCPKGT
CCCCEECCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHEEECCCCCCC
GTGGPGYTIKCEINNNKHQAGTLSMAHAGRDTGGSQFFICHAPQPHLDGVHTTFGQTQDM
CCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCH
DVVNAIRQGDKILSVKVSAE
HHHHHHHCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA