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The map label for this gene is argS [H]

Identifier: 158337656

GI number: 158337656

Start: 4573206

End: 4574960

Strand: Reverse

Name: argS [H]

Synonym: AM1_4538

Alternate gene names: 158337656

Gene position: 4574960-4573206 (Counterclockwise)

Preceding gene: 158339485

Following gene: 158337655

Centisome position: 70.34

GC content: 48.26

Gene sequence:

>1755_bases
ATGAAGTCCATCCTCAAAACCTTAGAGACTCGATTTGATCGAGCGTTAAACGCTGCCTTTGGAGCTGAGTTAGTGATTTC
TGTTCCGGTTGTTGGCGTCGCCAGTAATCCCAAGTTTGGTGACTACCAATCGAATGTCTCCCTAGCTTTGGCAAAGCCTT
TGGGGCAATCTCCTCGTGGAATTGCAGATCAGATTCTCCAACATTTAGAGGTCGATGATCTGTGCGAACCGCCTACCATT
GCTGGGCCAGGATTTATCAACTTAACCCTCAAGCCCACCTTTTTGGCAGAGCAACTTCAGCAAATGCAAGCCGATCCTCG
CTTAGGGATTGAGCCGATTGCTGATCCACAGCGGGTGATTGTTGATTTTTCTAGCCCCAATATCGCCAAAGAAATGCATG
TGGGCCATTTGCGGTCTACGATTATCGGCGACTGTATTGCCCGGATTCTCGAATTTCAAGGGAATGATGTGCTGCGGCTC
AATCATGTCGGAGATTGGGGCACCCAGTTTGGCATGCTGATTACTTACCTGTCTGAGGTGCACCCCGCAGCGTTAACCAC
CTCGGATGCTCTAGATTTAGGGGACTTAGTCGCGTTTTATAAAAAAGCCAAGCAGCGCTTTGATGAAGATGAAGACTTTC
AGGTGCAGTCCCGGAATGCAGTCGTCAAGCTGCAGCAAGGCGATTCAGAAGCCACTCAAGCTTGGCAACTCCTCTGCGAT
CAATCACGGCGTGAGTTCGAGAAGATTTATCGAGATTTGGATATTGAGCTGACGGAGCGAGGAGAGTCTTTTTATAATCC
CTTTCTAGCTGACGTTCTGACAGACTTGGATAAAGCAGGGCTTCTAGAAACAGATCAAGGGGCACAATGCGTCTTTTTGG
AAGGCTTCACCAATAAACAAGGGGATCCGCAACCGTTGATTGTCCAAAAGTCTGACGGTGGATTTAACTATGCCACCACA
GATTTAGCGGCTCTACGCCACCGGATCACTGCCGAGTCAGCACAACGATTGATCTATATCACGGATGCAGGGCAGGCCAA
TCATTTTGCCCAGGTTTTTCAAGTCGCTCGGCGAGCCCAGTGGATGCCTGAAACCATTCAAGTGGTACATATGCCCTTCG
GGTTGGTTCAGGGCGAAGACGGTAAGAAATTAAAAACTCGGTCAGGCAAAACGATTCGCTTACGAGATCTATTAGATGAA
GCCGTTACTCGCGCTCAAACGGATATCGAAACTCGACTTGCTGAAGAAGATCGAACTGAGTCCCCAGATTTTATTGCCAA
TGCTGCCCAGGTCATCGGATTGGGAGCAGTAAAGTATGCTGATCTCAGTCAAAACCGAACGAGCAATTATGTGTTTAGCT
ATGACAAAATGCTCGCTCTACAGGGAAACACGGCTCCCTACATGCTCTATGCCTATGTTCGAGTACAGGGGATTAGTCGC
AAAGGAAAGATTGATTTTTCCCAGTTAGATGATGTTTCCCTCATCATTGCTGAGCCTTCTGAGTTGGCTTTAGCAAAACA
CCTGTTGCAAATGCAGGACATCTTATCTGAAGTAGCTGCAGACCTATTACCCAACCGACTGTGCCAGTATCTATTCGAGC
TGAGCCAAAAGTTCAATCAGTTTTATGATCAATGTCCGGTCCTCAATGCAGAAGAACCGGCCCGAACCTCTCGTCTGGTA
TTGTCTGATCTCACGGCCCGCACGCTGAAGTTGGGGCTATCCCTATTGGGGATTGAAGTGCTGGAGCGGATGTAA

Upstream 100 bases:

>100_bases
GTCTCCGGCGGCATTGTGTATCTCACTGTCTCAGAGTGGCGTGATCGCAGACGACGCGAGCGCGAACAGCGTGCCGCTAG
GAAAAAACGCAGTTAAGCTC

Downstream 100 bases:

>100_bases
AGTCACACCTAAGTTCTACAAATTAGACAGGATTGGGGATGCGATCGCAAACCTCAATACGTCACACTAAATAAACAGGC
CTATGCTCGAAGCACCTCTT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MKSILKTLETRFDRALNAAFGAELVISVPVVGVASNPKFGDYQSNVSLALAKPLGQSPRGIADQILQHLEVDDLCEPPTI
AGPGFINLTLKPTFLAEQLQQMQADPRLGIEPIADPQRVIVDFSSPNIAKEMHVGHLRSTIIGDCIARILEFQGNDVLRL
NHVGDWGTQFGMLITYLSEVHPAALTTSDALDLGDLVAFYKKAKQRFDEDEDFQVQSRNAVVKLQQGDSEATQAWQLLCD
QSRREFEKIYRDLDIELTERGESFYNPFLADVLTDLDKAGLLETDQGAQCVFLEGFTNKQGDPQPLIVQKSDGGFNYATT
DLAALRHRITAESAQRLIYITDAGQANHFAQVFQVARRAQWMPETIQVVHMPFGLVQGEDGKKLKTRSGKTIRLRDLLDE
AVTRAQTDIETRLAEEDRTESPDFIANAAQVIGLGAVKYADLSQNRTSNYVFSYDKMLALQGNTAPYMLYAYVRVQGISR
KGKIDFSQLDDVSLIIAEPSELALAKHLLQMQDILSEVAADLLPNRLCQYLFELSQKFNQFYDQCPVLNAEEPARTSRLV
LSDLTARTLKLGLSLLGIEVLERM

Sequences:

>Translated_584_residues
MKSILKTLETRFDRALNAAFGAELVISVPVVGVASNPKFGDYQSNVSLALAKPLGQSPRGIADQILQHLEVDDLCEPPTI
AGPGFINLTLKPTFLAEQLQQMQADPRLGIEPIADPQRVIVDFSSPNIAKEMHVGHLRSTIIGDCIARILEFQGNDVLRL
NHVGDWGTQFGMLITYLSEVHPAALTTSDALDLGDLVAFYKKAKQRFDEDEDFQVQSRNAVVKLQQGDSEATQAWQLLCD
QSRREFEKIYRDLDIELTERGESFYNPFLADVLTDLDKAGLLETDQGAQCVFLEGFTNKQGDPQPLIVQKSDGGFNYATT
DLAALRHRITAESAQRLIYITDAGQANHFAQVFQVARRAQWMPETIQVVHMPFGLVQGEDGKKLKTRSGKTIRLRDLLDE
AVTRAQTDIETRLAEEDRTESPDFIANAAQVIGLGAVKYADLSQNRTSNYVFSYDKMLALQGNTAPYMLYAYVRVQGISR
KGKIDFSQLDDVSLIIAEPSELALAKHLLQMQDILSEVAADLLPNRLCQYLFELSQKFNQFYDQCPVLNAEEPARTSRLV
LSDLTARTLKLGLSLLGIEVLERM
>Mature_584_residues
MKSILKTLETRFDRALNAAFGAELVISVPVVGVASNPKFGDYQSNVSLALAKPLGQSPRGIADQILQHLEVDDLCEPPTI
AGPGFINLTLKPTFLAEQLQQMQADPRLGIEPIADPQRVIVDFSSPNIAKEMHVGHLRSTIIGDCIARILEFQGNDVLRL
NHVGDWGTQFGMLITYLSEVHPAALTTSDALDLGDLVAFYKKAKQRFDEDEDFQVQSRNAVVKLQQGDSEATQAWQLLCD
QSRREFEKIYRDLDIELTERGESFYNPFLADVLTDLDKAGLLETDQGAQCVFLEGFTNKQGDPQPLIVQKSDGGFNYATT
DLAALRHRITAESAQRLIYITDAGQANHFAQVFQVARRAQWMPETIQVVHMPFGLVQGEDGKKLKTRSGKTIRLRDLLDE
AVTRAQTDIETRLAEEDRTESPDFIANAAQVIGLGAVKYADLSQNRTSNYVFSYDKMLALQGNTAPYMLYAYVRVQGISR
KGKIDFSQLDDVSLIIAEPSELALAKHLLQMQDILSEVAADLLPNRLCQYLFELSQKFNQFYDQCPVLNAEEPARTSRLV
LSDLTARTLKLGLSLLGIEVLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=600, Percent_Identity=41, Blast_Score=468, Evalue=1e-132,
Organism=Homo sapiens, GI197100773, Length=593, Percent_Identity=30.185497470489, Blast_Score=225, Evalue=1e-58,
Organism=Escherichia coli, GI1788184, Length=561, Percent_Identity=47.5935828877005, Blast_Score=529, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI71985061, Length=609, Percent_Identity=40.3940886699507, Blast_Score=421, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI71985068, Length=588, Percent_Identity=41.156462585034, Blast_Score=411, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17532153, Length=503, Percent_Identity=24.6520874751491, Blast_Score=143, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320548, Length=552, Percent_Identity=29.5289855072464, Blast_Score=223, Evalue=7e-59,
Organism=Saccharomyces cerevisiae, GI6321883, Length=488, Percent_Identity=27.8688524590164, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI18859963, Length=601, Percent_Identity=41.4309484193012, Blast_Score=462, Evalue=1e-130,
Organism=Drosophila melanogaster, GI28571570, Length=512, Percent_Identity=29.4921875, Blast_Score=175, Evalue=8e-44,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 65086; Mature: 65086

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSILKTLETRFDRALNAAFGAELVISVPVVGVASNPKFGDYQSNVSLALAKPLGQSPRG
CHHHHHHHHHHHHHHHHHHHCCEEEEEECEEEECCCCCCCCCCCCCEEEEECCCCCCCCC
IADQILQHLEVDDLCEPPTIAGPGFINLTLKPTFLAEQLQQMQADPRLGIEPIADPQRVI
HHHHHHHHCCHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
VDFSSPNIAKEMHVGHLRSTIIGDCIARILEFQGNDVLRLNHVGDWGTQFGMLITYLSEV
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
HPAALTTSDALDLGDLVAFYKKAKQRFDEDEDFQVQSRNAVVKLQQGDSEATQAWQLLCD
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCHHHHHHHHHHH
QSRREFEKIYRDLDIELTERGESFYNPFLADVLTDLDKAGLLETDQGAQCVFLEGFTNKQ
HHHHHHHHHHHCCCCEEHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCC
GDPQPLIVQKSDGGFNYATTDLAALRHRITAESAQRLIYITDAGQANHFAQVFQVARRAQ
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHC
WMPETIQVVHMPFGLVQGEDGKKLKTRSGKTIRLRDLLDEAVTRAQTDIETRLAEEDRTE
CCCHHHHEEECCCCEEECCCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
SPDFIANAAQVIGLGAVKYADLSQNRTSNYVFSYDKMLALQGNTAPYMLYAYVRVQGISR
CCHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECEEEEEECCCCCEEEEEEEEHCCCCC
KGKIDFSQLDDVSLIIAEPSELALAKHLLQMQDILSEVAADLLPNRLCQYLFELSQKFNQ
CCCCCHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYDQCPVLNAEEPARTSRLVLSDLTARTLKLGLSLLGIEVLERM
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSILKTLETRFDRALNAAFGAELVISVPVVGVASNPKFGDYQSNVSLALAKPLGQSPRG
CHHHHHHHHHHHHHHHHHHHCCEEEEEECEEEECCCCCCCCCCCCCEEEEECCCCCCCCC
IADQILQHLEVDDLCEPPTIAGPGFINLTLKPTFLAEQLQQMQADPRLGIEPIADPQRVI
HHHHHHHHCCHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
VDFSSPNIAKEMHVGHLRSTIIGDCIARILEFQGNDVLRLNHVGDWGTQFGMLITYLSEV
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
HPAALTTSDALDLGDLVAFYKKAKQRFDEDEDFQVQSRNAVVKLQQGDSEATQAWQLLCD
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCHHHHHHHHHHH
QSRREFEKIYRDLDIELTERGESFYNPFLADVLTDLDKAGLLETDQGAQCVFLEGFTNKQ
HHHHHHHHHHHCCCCEEHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCC
GDPQPLIVQKSDGGFNYATTDLAALRHRITAESAQRLIYITDAGQANHFAQVFQVARRAQ
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHC
WMPETIQVVHMPFGLVQGEDGKKLKTRSGKTIRLRDLLDEAVTRAQTDIETRLAEEDRTE
CCCHHHHEEECCCCEEECCCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
SPDFIANAAQVIGLGAVKYADLSQNRTSNYVFSYDKMLALQGNTAPYMLYAYVRVQGISR
CCHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECEEEEEECCCCCEEEEEEEEHCCCCC
KGKIDFSQLDDVSLIIAEPSELALAKHLLQMQDILSEVAADLLPNRLCQYLFELSQKFNQ
CCCCCHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYDQCPVLNAEEPARTSRLVLSDLTARTLKLGLSLLGIEVLERM
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA