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The map label for this gene is hldD [H]

Identifier: 158337592

GI number: 158337592

Start: 4498361

End: 4499500

Strand: Reverse

Name: hldD [H]

Synonym: AM1_4473

Alternate gene names: 158337592

Gene position: 4499500-4498361 (Counterclockwise)

Preceding gene: 158337593

Following gene: 158337591

Centisome position: 69.18

GC content: 48.77

Gene sequence:

>1140_bases
ATGTCACCGTTTCCCCTAGACCGCTTTGATCTGAATGCTCAGGATATTCAAGATTGGTATGTCAACAAAACCCTTAATGA
TCCCCATCGACTAGCGATTCAAGCGCTGCAGTCTCAACGCATTTGCGTTATGGGAGGCTGCGGTCAGGTGGGTTCCCACC
TGGTGACCAAGCTCTATGAATTTGGCTATCCCTTGGATCACCTGACCATCAACGATGATTTACGCCTGGGTAGGCGGGAA
AATTTACCAGCTATTCTGAGAGACCAAGTGGATACCCGCTGCCACAAAGACTATGCTCTTAATCCCGGCACCCAGCCAGA
TATGGTCATTTTTGTGGGAGGGCGCTCTAGTGTGCCCCACTTCCATACCCTGGAAGAGGTCTTAGATGAAGTCGATAGCT
GGAAAACGGTTCTGGAATGGTGTGTTGCTGAAAATATCCGCTTGATTTTTGCCTCCACTAGCAGTCTGTGCAAAAAACGC
CCGTCCCTTGAGGATCAGCGCGTGTGGCCTGCCTCCCTCTATGAAGCCGCCAAGCTGATGATGGAAGATATGGCCATCCA
GCAAGCCCTATGCAACGACTTAGCGGTTCAAATCTGCCGATTTTTCTCTATCTATGGCGTAACAGAGCAGCATAAGGGCA
AGTTTGGCAATCTATATACGCAGATTTTGTGGCATAGCTTAGAGCAGACCCCCTTTGAACTTTGGGGACGTCAAGGTCAG
TTTTCCCCCGGAGAACAGACCCGCGATACGATTTTTGCTGCGGAAGTGTCCCGCGCCTTACTGTACTTATTAACGTTGCC
TAAGCCTCGCCCTCAGATTAATAACATCTCAGACTTGGTCTACAACATTGGCCAAGGGCAACCCACTGCCATTCGCACCA
TGATTGGTCAAATCGAGGCATTGTTGCCCTCGGACTGTCAGCCGATCATCGTTGAATCTGAAGTACCAGAAGAGATTCAA
AACTATGTCGTCCATACCTGGGGCAACCCCCATAAACTCTTAGGAACTGATTTTAGTCCTCAATTTACCGAACATCCCGA
TAACCTCAAATTCATTACCTATGCTCTGTTGAGTAACATGGATTGGTATTGGTCCATTGTCGAGCAGTTACGGGAGCAGT
CCTTAGTAAGCGTGGTTTAG

Upstream 100 bases:

>100_bases
CGAATTGACAACCTTGCGTAGGGTACACTCCAGAACACAGCCCAAAACGCCATAAAGCCAAAATTCTCTGTATAGTGCCA
AGAGCAACCCCTGTTCTCCC

Downstream 100 bases:

>100_bases
CCCTGTTGCTGCAGGACGAAAGACATCAAAAGGGAATGCTGAAGGGAGCTGACCACCGCTGAGAAAATATGACACACTCA
GAACAGTGGACTCAAGCCAG

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: ADP-L-glycero-beta-D-manno-heptose-6-epimerase; ADP-glyceromanno-heptose 6-epimerase; ADP-hep 6-epimerase; AGME [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSPFPLDRFDLNAQDIQDWYVNKTLNDPHRLAIQALQSQRICVMGGCGQVGSHLVTKLYEFGYPLDHLTINDDLRLGRRE
NLPAILRDQVDTRCHKDYALNPGTQPDMVIFVGGRSSVPHFHTLEEVLDEVDSWKTVLEWCVAENIRLIFASTSSLCKKR
PSLEDQRVWPASLYEAAKLMMEDMAIQQALCNDLAVQICRFFSIYGVTEQHKGKFGNLYTQILWHSLEQTPFELWGRQGQ
FSPGEQTRDTIFAAEVSRALLYLLTLPKPRPQINNISDLVYNIGQGQPTAIRTMIGQIEALLPSDCQPIIVESEVPEEIQ
NYVVHTWGNPHKLLGTDFSPQFTEHPDNLKFITYALLSNMDWYWSIVEQLREQSLVSVV

Sequences:

>Translated_379_residues
MSPFPLDRFDLNAQDIQDWYVNKTLNDPHRLAIQALQSQRICVMGGCGQVGSHLVTKLYEFGYPLDHLTINDDLRLGRRE
NLPAILRDQVDTRCHKDYALNPGTQPDMVIFVGGRSSVPHFHTLEEVLDEVDSWKTVLEWCVAENIRLIFASTSSLCKKR
PSLEDQRVWPASLYEAAKLMMEDMAIQQALCNDLAVQICRFFSIYGVTEQHKGKFGNLYTQILWHSLEQTPFELWGRQGQ
FSPGEQTRDTIFAAEVSRALLYLLTLPKPRPQINNISDLVYNIGQGQPTAIRTMIGQIEALLPSDCQPIIVESEVPEEIQ
NYVVHTWGNPHKLLGTDFSPQFTEHPDNLKFITYALLSNMDWYWSIVEQLREQSLVSVV
>Mature_378_residues
SPFPLDRFDLNAQDIQDWYVNKTLNDPHRLAIQALQSQRICVMGGCGQVGSHLVTKLYEFGYPLDHLTINDDLRLGRREN
LPAILRDQVDTRCHKDYALNPGTQPDMVIFVGGRSSVPHFHTLEEVLDEVDSWKTVLEWCVAENIRLIFASTSSLCKKRP
SLEDQRVWPASLYEAAKLMMEDMAIQQALCNDLAVQICRFFSIYGVTEQHKGKFGNLYTQILWHSLEQTPFELWGRQGQF
SPGEQTRDTIFAAEVSRALLYLLTLPKPRPQINNISDLVYNIGQGQPTAIRTMIGQIEALLPSDCQPIIVESEVPEEIQN
YVVHTWGNPHKLLGTDFSPQFTEHPDNLKFITYALLSNMDWYWSIVEQLREQSLVSVV

Specific function: Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. HldD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR011912
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.20 [H]

Molecular weight: Translated: 43364; Mature: 43233

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPFPLDRFDLNAQDIQDWYVNKTLNDPHRLAIQALQSQRICVMGGCGQVGSHLVTKLYE
CCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHH
FGYPLDHLTINDDLRLGRRENLPAILRDQVDTRCHKDYALNPGTQPDMVIFVGGRSSVPH
HCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCH
FHTLEEVLDEVDSWKTVLEWCVAENIRLIFASTSSLCKKRPSLEDQRVWPASLYEAAKLM
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCCCCCCCCHHHHHHHHHHH
MEDMAIQQALCNDLAVQICRFFSIYGVTEQHKGKFGNLYTQILWHSLEQTPFELWGRQGQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHCCHHHHCCCCCC
FSPGEQTRDTIFAAEVSRALLYLLTLPKPRPQINNISDLVYNIGQGQPTAIRTMIGQIEA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHH
LLPSDCQPIIVESEVPEEIQNYVVHTWGNPHKLLGTDFSPQFTEHPDNLKFITYALLSNM
HCCCCCCCEEECCCCCHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
DWYWSIVEQLREQSLVSVV
CHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPFPLDRFDLNAQDIQDWYVNKTLNDPHRLAIQALQSQRICVMGGCGQVGSHLVTKLYE
CCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHH
FGYPLDHLTINDDLRLGRRENLPAILRDQVDTRCHKDYALNPGTQPDMVIFVGGRSSVPH
HCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCH
FHTLEEVLDEVDSWKTVLEWCVAENIRLIFASTSSLCKKRPSLEDQRVWPASLYEAAKLM
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCCCCCCCCHHHHHHHHHHH
MEDMAIQQALCNDLAVQICRFFSIYGVTEQHKGKFGNLYTQILWHSLEQTPFELWGRQGQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHCCHHHHCCCCCC
FSPGEQTRDTIFAAEVSRALLYLLTLPKPRPQINNISDLVYNIGQGQPTAIRTMIGQIEA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHH
LLPSDCQPIIVESEVPEEIQNYVVHTWGNPHKLLGTDFSPQFTEHPDNLKFITYALLSNM
HCCCCCCCEEECCCCCHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
DWYWSIVEQLREQSLVSVV
CHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA