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The map label for this gene is dinF [H]

Identifier: 158337561

GI number: 158337561

Start: 4469490

End: 4470848

Strand: Direct

Name: dinF [H]

Synonym: AM1_4442

Alternate gene names: 158337561

Gene position: 4469490-4470848 (Clockwise)

Preceding gene: 158337560

Following gene: 158337562

Centisome position: 68.72

GC content: 49.08

Gene sequence:

>1359_bases
ATGGCCTCGTCCACTCCCATCAATCATGATCTCAAGTCTTTTTTTCGGCTAGCTATCATCAACGTCCTTGCTAACTTGAT
GGTGCCCCTGGCAGGACTGTTTGATGTTGCTTTTTTGGGGCATCTCGATCAGTTGTGGTATTTAGCTGGCGTTGCCCTGG
CCACGGTGCTGTTTAACTATCTCTATTGGACCTTTGGCTTTCTAAGAATGGGAACCACGGGTATGACAGCTCAGGCCTTG
GGAAGAAATGACTCCGACGCAATGCTGCTAGTGGGCCTTCGTAATGGGGTAGTCGCTGTAGGGTTAGGGCTGGGTATTCT
ACTCTTGCAATGGCCGATTAAAGCGTTGGGATTTAGTCTGCTGAGCGCCATGCCAGCAGTCAAAGCGGCCGGTATGGACT
ACTTTGACGCTCTGATTTGGGGAGCACCCGCAACATTGCTCAATTTTGTCGTGGTGGGATGGTACTTAGGGCGAGCCCAA
AGTCGAAAGGTCTTGCTGCTGTCTGGAGTCAATAATTTTACGAATGTCGGCTTCAATTACCTCTTTATTGTTCAGTGGGG
ATGGCAAAGTACCGGAGCCGGTGCTGCTACAGCTCTGAGCCAATATCTAATGCTGGGGGTAGGATTAGCCTTGATAGGTA
GAGATATCTCCTGGCCTCAACTCCAAACGGTCTGGCCCCAAGTGCTTCAAGGAACAGCGCTTCGGCAAACATTGACCTTC
AATCGAGACATCTTAGTACGAACCTTTGCCCTGATTTCTACGTTTGCCGTATTTACCAACTTAAGTTCTGACCTAGGTAC
AGATGTCTTATCAACCAATACCTTGCTGTTACAGGTGGTCACCCTTGCATCCTACTTTATCGATGGCATCGCGTTTGCGA
TGGAAAGTGTAACGGGGGTTCTGAGCCAGCAAAATCAACCTCAGCGTTTGCGGCAGCTGCTGACCTTATCAGGTTTTACC
AGCGTTGGCTTAGGGGTTGGTTTCGCCTTAGCGTTCTATCTATTCCCTCAACCGCTATTTAGTCTGCTCACCCATCATCC
AGAAGTTTTGGCCCAGGTCAATCAGTATGTGGTTTGGCTTCTGCCTGTATTGGGTTTCGGTGCGATTGCGTATTTGTTAG
ATGGTTATTTTCTAGGCTTAACAGCGGGCCAACACCTTCGCCATTCTGTATTAATCGCCACATTGTTTGGGTTCCTTCCT
CTAGCAATAGCGTCATGGTATTGGCAGCAAGTTCACTTGCTCTGGTTAGCGCTAGCTCTATTTATGGGCAGCCGGGCCAT
TGTCATGGTCATCCAAGTTCCTCGGTCACTCAAGCGTGCCCATGGAACACCTGTTGTTCATTCTGGTCAAAAAGGGTAG

Upstream 100 bases:

>100_bases
CCACTCCAAGGAGTCTTAATTGCATGGGCTTGGTGGTTTACAAAGCCAGATTTACCAGCTAGTCAAAACATTCGCTGATT
CAGCACCTTTCGCCCCTGCC

Downstream 100 bases:

>100_bases
GGACCCTCTGCTATGGATCTGGCGAGCCTCCCGGTTACTGACGGATAGAGTCCAGGACGTACCCCATGTTCAGAAAAACT
CTGCTGGCTTGTTTTCTCAC

Product: MatE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MASSTPINHDLKSFFRLAIINVLANLMVPLAGLFDVAFLGHLDQLWYLAGVALATVLFNYLYWTFGFLRMGTTGMTAQAL
GRNDSDAMLLVGLRNGVVAVGLGLGILLLQWPIKALGFSLLSAMPAVKAAGMDYFDALIWGAPATLLNFVVVGWYLGRAQ
SRKVLLLSGVNNFTNVGFNYLFIVQWGWQSTGAGAATALSQYLMLGVGLALIGRDISWPQLQTVWPQVLQGTALRQTLTF
NRDILVRTFALISTFAVFTNLSSDLGTDVLSTNTLLLQVVTLASYFIDGIAFAMESVTGVLSQQNQPQRLRQLLTLSGFT
SVGLGVGFALAFYLFPQPLFSLLTHHPEVLAQVNQYVVWLLPVLGFGAIAYLLDGYFLGLTAGQHLRHSVLIATLFGFLP
LAIASWYWQQVHLLWLALALFMGSRAIVMVIQVPRSLKRAHGTPVVHSGQKG

Sequences:

>Translated_452_residues
MASSTPINHDLKSFFRLAIINVLANLMVPLAGLFDVAFLGHLDQLWYLAGVALATVLFNYLYWTFGFLRMGTTGMTAQAL
GRNDSDAMLLVGLRNGVVAVGLGLGILLLQWPIKALGFSLLSAMPAVKAAGMDYFDALIWGAPATLLNFVVVGWYLGRAQ
SRKVLLLSGVNNFTNVGFNYLFIVQWGWQSTGAGAATALSQYLMLGVGLALIGRDISWPQLQTVWPQVLQGTALRQTLTF
NRDILVRTFALISTFAVFTNLSSDLGTDVLSTNTLLLQVVTLASYFIDGIAFAMESVTGVLSQQNQPQRLRQLLTLSGFT
SVGLGVGFALAFYLFPQPLFSLLTHHPEVLAQVNQYVVWLLPVLGFGAIAYLLDGYFLGLTAGQHLRHSVLIATLFGFLP
LAIASWYWQQVHLLWLALALFMGSRAIVMVIQVPRSLKRAHGTPVVHSGQKG
>Mature_451_residues
ASSTPINHDLKSFFRLAIINVLANLMVPLAGLFDVAFLGHLDQLWYLAGVALATVLFNYLYWTFGFLRMGTTGMTAQALG
RNDSDAMLLVGLRNGVVAVGLGLGILLLQWPIKALGFSLLSAMPAVKAAGMDYFDALIWGAPATLLNFVVVGWYLGRAQS
RKVLLLSGVNNFTNVGFNYLFIVQWGWQSTGAGAATALSQYLMLGVGLALIGRDISWPQLQTVWPQVLQGTALRQTLTFN
RDILVRTFALISTFAVFTNLSSDLGTDVLSTNTLLLQVVTLASYFIDGIAFAMESVTGVLSQQNQPQRLRQLLTLSGFTS
VGLGVGFALAFYLFPQPLFSLLTHHPEVLAQVNQYVVWLLPVLGFGAIAYLLDGYFLGLTAGQHLRHSVLIATLFGFLPL
AIASWYWQQVHLLWLALALFMGSRAIVMVIQVPRSLKRAHGTPVVHSGQKG

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=423, Percent_Identity=31.9148936170213, Blast_Score=154, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49270; Mature: 49138

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSTPINHDLKSFFRLAIINVLANLMVPLAGLFDVAFLGHLDQLWYLAGVALATVLFNY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYWTFGFLRMGTTGMTAQALGRNDSDAMLLVGLRNGVVAVGLGLGILLLQWPIKALGFSL
HHHHHHHHHHCCCCCHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LSAMPAVKAAGMDYFDALIWGAPATLLNFVVVGWYLGRAQSRKVLLLSGVNNFTNVGFNY
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHCCCEE
LFIVQWGWQSTGAGAATALSQYLMLGVGLALIGRDISWPQLQTVWPQVLQGTALRQTLTF
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHC
NRDILVRTFALISTFAVFTNLSSDLGTDVLSTNTLLLQVVTLASYFIDGIAFAMESVTGV
CHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQQNQPQRLRQLLTLSGFTSVGLGVGFALAFYLFPQPLFSLLTHHPEVLAQVNQYVVWL
HHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LPVLGFGAIAYLLDGYFLGLTAGQHLRHSVLIATLFGFLPLAIASWYWQQVHLLWLALAL
HHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMGSRAIVMVIQVPRSLKRAHGTPVVHSGQKG
HHCCCCEEEEECCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ASSTPINHDLKSFFRLAIINVLANLMVPLAGLFDVAFLGHLDQLWYLAGVALATVLFNY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYWTFGFLRMGTTGMTAQALGRNDSDAMLLVGLRNGVVAVGLGLGILLLQWPIKALGFSL
HHHHHHHHHHCCCCCHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LSAMPAVKAAGMDYFDALIWGAPATLLNFVVVGWYLGRAQSRKVLLLSGVNNFTNVGFNY
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHCCCEE
LFIVQWGWQSTGAGAATALSQYLMLGVGLALIGRDISWPQLQTVWPQVLQGTALRQTLTF
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHC
NRDILVRTFALISTFAVFTNLSSDLGTDVLSTNTLLLQVVTLASYFIDGIAFAMESVTGV
CHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQQNQPQRLRQLLTLSGFTSVGLGVGFALAFYLFPQPLFSLLTHHPEVLAQVNQYVVWL
HHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LPVLGFGAIAYLLDGYFLGLTAGQHLRHSVLIATLFGFLPLAIASWYWQQVHLLWLALAL
HHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMGSRAIVMVIQVPRSLKRAHGTPVVHSGQKG
HHCCCCEEEEECCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]