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The map label for this gene is cikA [H]

Identifier: 158337549

GI number: 158337549

Start: 4454310

End: 4456517

Strand: Reverse

Name: cikA [H]

Synonym: AM1_4430

Alternate gene names: 158337549

Gene position: 4456517-4454310 (Counterclockwise)

Preceding gene: 158337551

Following gene: 158337545

Centisome position: 68.52

GC content: 50.18

Gene sequence:

>2208_bases
ATGATGCCTGTTTCAGCACCAGAAATATTTGAGCATACCTTGCCGCAGCACGTCTATCCGCAATTGAGCTTGTCTCTAGC
AGATATGGTGCGGTCTGTTCCTGGTGTTGCCAAACTCCTCACCAGCGTGGAGGTTGGAGCGATGGTTCCGGAGACACAGC
GGTTTACCGTCCTCACCTCAAAAAGCTTTAGTGCCTTGGTCTATGAAGCGGAGAAAGCTCAACTCAAGCTGACGTTTGAA
CCAATGGCCATTACGACATTCTTGGAGCGCCTCTACCAACATTGCCCTGCGGGGTCCCCGCTTCAACAGCGGATTACTGA
AGTTCGAGAGCGTCAGTCTCGCAAAAATAATGATGCCAAGCTTCAGGGACAATTTACGCTGCTCTCCCTCGCGGCGATGT
ATCCAGGTCCTAGAGCAGAAGCGGTTCCCTTAGCCCCGGAGGTGACCCTCCACCCCACCGCAAATCAGGAACGTCTCAGC
CATCAAATTATCTCTCAGCTGAGCCAAGGGGTAGAATTACCCGCCCTTTTGTCGATGGTGGTAGAAGAGCTCCGTCATCT
GCTCCAGGCCGATCGTCTACTGATTTATCAACTGTCGCCGACTGCTCCCTCTGGTGCTGAGTCTCATCATCCGGTTTCTG
CTCAATCAGGCTCCGTCGTCCATGAAGCCTTGGCCTCTTCTGAGTTGCCCTCTGTGTTATCTGATCAGGAACAGCTGTGG
GGCATCGCTTCATCTGAGTCTCTGCTCAAATATCAGCAGGGCTATACCTTAGCGATCCATGATGTTCTGCAAAATGATTC
CGTCTCTGAACCCTTAGCAAAGGTTCTAGACTCAATTCAAGTGAGAGCATTGCTGGTGACCCCAATCTTGGTCAAGTCTG
AACTCTGGGGCCTATTAATTGCTCACCAGTGCCTTCACCCCCGCCAATGGCAGGTTCAAGAACAAGATTTACTGAAGCGA
ATGGCTGAACATGTTGCCATTGCCATTCATCAGGCTGCTTTGCAGGATCAAGTTCGGCAACATAAGCAAACCTTAGATAA
GCAGGTAGAACAACGCACTCAAGAACTCCATGCTGCACTGCTCGCAGCACAATCTTCAAATCAGGCTAAAAGCGATTTCT
TGGCAACCATGAGCCATGAATTACGCACGCCGCTCACCTGCGTGATTGGCATGTCGGCTACTTTATTGCGCTGGTCTTTA
GGCCCCCTGACAGATAAGCAACGGAGCTGCCTACAAACGATTCATGACAGCGGCGAGCATTTGCTGGAGTTGATCAATGA
CATTCTGGATTTCTCCCATGTGCAATCCGGTAAAGCCACCCTCAACGTCAGTGATTTTTCCCTCACTACCTTAGTTCAAC
AGCTCTTGCAAGTTATGCGAGATAAGGCGGATGCCCATCAAGTGCAGCTCAAGGCTAATTTGAAGATTCCCCCGGAGCGA
GACCGATTTATTGCTGATTTACGGCGAGTCCAGCAAATTCTAATCAGTCTGACGGATAACGCCATTAAATTTACGCCCAT
GGGGGGGAAGGTAACGTTGCGCGTATGGGTTGAAACCAATACCGTTGTGTTCCAGGTAGAAGACACGGGCATTGGCATTT
CTTCGAGTCAACTGCCCCACCTGTTTGAAAAGTTTCAGCAATTAGATGGGTCCTATCATCGCACCTACGAAGGGGCTGGC
TTAGGGCTAGCCTTAGCCCAGCAATGTGTGACCCTGCATCAAGGGTGGATTGATGTCAGTTCAGAGGAAGGACAAGGGTC
AATTTTTACAGTTCAGTTACCGAATCAATCGGCTCTGTTTCAACAAGAAACCTCATCTCAACCCCTATCAGCTGGACGCA
TAGTGTTGATAGAAGGCCATGAAGAGGATGCGACCCTGCTGTGCGATATGTTGACAGCAGCAAACTATCAGGTGATTTGG
ATGGTTGAAGCGTCCGCTGCCATTGACCAAATCCGCTTGCTGCAGCCGATTGCCGTGATTGTGGATGCCCAATTGCCAGC
CCAAGGCTGCCTGGGTTTAATTCGTCGCCTAAGAGCGCTACCAGGCACGGATAAGATCAAAATCATCGTCCTCACCCAGG
AAGGGATTTCCAAAGATCATCAGCGGTATTTAAGCCTGGGTGCAGATGCTTACTTACTGAAGTCTCTGCAACCCGAAGAT
CTGTTGCGCAAAGTGAATGTGTTATTGAAGTCTGCGTCTGTGCTCTAG

Upstream 100 bases:

>100_bases
TAGCCACTTAAAGTCGTTCATGCCATAGAAAAAGTATCCACGAATTTGAAGAGCCATCAGGCTTCTCCGGGGGAAGCTGG
ATACAAGTGCAGGAGACTGG

Downstream 100 bases:

>100_bases
CTGCTCTAGAACTCCATCACCCGTTACTCTAGTTCTTTTGTGGCTTCCTCAGCATAGAGATTTGCCATCAAAGATTTTAA
GCGCATCCGAGGAATATAAG

Product: circadian input kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 735; Mature: 735

Protein sequence:

>735_residues
MMPVSAPEIFEHTLPQHVYPQLSLSLADMVRSVPGVAKLLTSVEVGAMVPETQRFTVLTSKSFSALVYEAEKAQLKLTFE
PMAITTFLERLYQHCPAGSPLQQRITEVRERQSRKNNDAKLQGQFTLLSLAAMYPGPRAEAVPLAPEVTLHPTANQERLS
HQIISQLSQGVELPALLSMVVEELRHLLQADRLLIYQLSPTAPSGAESHHPVSAQSGSVVHEALASSELPSVLSDQEQLW
GIASSESLLKYQQGYTLAIHDVLQNDSVSEPLAKVLDSIQVRALLVTPILVKSELWGLLIAHQCLHPRQWQVQEQDLLKR
MAEHVAIAIHQAALQDQVRQHKQTLDKQVEQRTQELHAALLAAQSSNQAKSDFLATMSHELRTPLTCVIGMSATLLRWSL
GPLTDKQRSCLQTIHDSGEHLLELINDILDFSHVQSGKATLNVSDFSLTTLVQQLLQVMRDKADAHQVQLKANLKIPPER
DRFIADLRRVQQILISLTDNAIKFTPMGGKVTLRVWVETNTVVFQVEDTGIGISSSQLPHLFEKFQQLDGSYHRTYEGAG
LGLALAQQCVTLHQGWIDVSSEEGQGSIFTVQLPNQSALFQQETSSQPLSAGRIVLIEGHEEDATLLCDMLTAANYQVIW
MVEASAAIDQIRLLQPIAVIVDAQLPAQGCLGLIRRLRALPGTDKIKIIVLTQEGISKDHQRYLSLGADAYLLKSLQPED
LLRKVNVLLKSASVL

Sequences:

>Translated_735_residues
MMPVSAPEIFEHTLPQHVYPQLSLSLADMVRSVPGVAKLLTSVEVGAMVPETQRFTVLTSKSFSALVYEAEKAQLKLTFE
PMAITTFLERLYQHCPAGSPLQQRITEVRERQSRKNNDAKLQGQFTLLSLAAMYPGPRAEAVPLAPEVTLHPTANQERLS
HQIISQLSQGVELPALLSMVVEELRHLLQADRLLIYQLSPTAPSGAESHHPVSAQSGSVVHEALASSELPSVLSDQEQLW
GIASSESLLKYQQGYTLAIHDVLQNDSVSEPLAKVLDSIQVRALLVTPILVKSELWGLLIAHQCLHPRQWQVQEQDLLKR
MAEHVAIAIHQAALQDQVRQHKQTLDKQVEQRTQELHAALLAAQSSNQAKSDFLATMSHELRTPLTCVIGMSATLLRWSL
GPLTDKQRSCLQTIHDSGEHLLELINDILDFSHVQSGKATLNVSDFSLTTLVQQLLQVMRDKADAHQVQLKANLKIPPER
DRFIADLRRVQQILISLTDNAIKFTPMGGKVTLRVWVETNTVVFQVEDTGIGISSSQLPHLFEKFQQLDGSYHRTYEGAG
LGLALAQQCVTLHQGWIDVSSEEGQGSIFTVQLPNQSALFQQETSSQPLSAGRIVLIEGHEEDATLLCDMLTAANYQVIW
MVEASAAIDQIRLLQPIAVIVDAQLPAQGCLGLIRRLRALPGTDKIKIIVLTQEGISKDHQRYLSLGADAYLLKSLQPED
LLRKVNVLLKSASVL
>Mature_735_residues
MMPVSAPEIFEHTLPQHVYPQLSLSLADMVRSVPGVAKLLTSVEVGAMVPETQRFTVLTSKSFSALVYEAEKAQLKLTFE
PMAITTFLERLYQHCPAGSPLQQRITEVRERQSRKNNDAKLQGQFTLLSLAAMYPGPRAEAVPLAPEVTLHPTANQERLS
HQIISQLSQGVELPALLSMVVEELRHLLQADRLLIYQLSPTAPSGAESHHPVSAQSGSVVHEALASSELPSVLSDQEQLW
GIASSESLLKYQQGYTLAIHDVLQNDSVSEPLAKVLDSIQVRALLVTPILVKSELWGLLIAHQCLHPRQWQVQEQDLLKR
MAEHVAIAIHQAALQDQVRQHKQTLDKQVEQRTQELHAALLAAQSSNQAKSDFLATMSHELRTPLTCVIGMSATLLRWSL
GPLTDKQRSCLQTIHDSGEHLLELINDILDFSHVQSGKATLNVSDFSLTTLVQQLLQVMRDKADAHQVQLKANLKIPPER
DRFIADLRRVQQILISLTDNAIKFTPMGGKVTLRVWVETNTVVFQVEDTGIGISSSQLPHLFEKFQQLDGSYHRTYEGAG
LGLALAQQCVTLHQGWIDVSSEEGQGSIFTVQLPNQSALFQQETSSQPLSAGRIVLIEGHEEDATLLCDMLTAANYQVIW
MVEASAAIDQIRLLQPIAVIVDAQLPAQGCLGLIRRLRALPGTDKIKIIVLTQEGISKDHQRYLSLGADAYLLKSLQPED
LLRKVNVLLKSASVL

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:
GO:0000155: Circadian input kinase
GO:0000156: Circadian input kinase
GO:0000160: Circadian input kinase
GO:0004673: Circadian input kinase
GO:0004871: Circadian input kinase
GO:0005524: Circadian input kinase
GO:0006355: Circadian input kinase
GO:0007165: Circadian input kinase
GO:0008020: Circadian input kinase
GO:0009584: Circadian input kinase
GO:0016020: Circadian input kinase
GO:0016301: Circadian input kinase
GO:0016310: Circadian input kinase
GO:0016772: Circadian input kinase
GO:0018106: Circadian input kinase
GO:0018298: Circadian input kinase

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=353, Percent_Identity=33.7110481586402, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI87081816, Length=386, Percent_Identity=30.3108808290155, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI48994928, Length=364, Percent_Identity=31.5934065934066, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI145693157, Length=269, Percent_Identity=33.457249070632, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1788713, Length=359, Percent_Identity=28.133704735376, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=27.1551724137931, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1788393, Length=281, Percent_Identity=25.6227758007117, Blast_Score=93, Evalue=8e-20,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=29.4605809128631, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=28.8888888888889, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786783, Length=266, Percent_Identity=25.9398496240602, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=29.2792792792793, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790346, Length=289, Percent_Identity=26.643598615917, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=228, Percent_Identity=28.5087719298246, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1790861, Length=224, Percent_Identity=27.2321428571429, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=229, Percent_Identity=24.0174672489083, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787894, Length=231, Percent_Identity=25.5411255411255, Blast_Score=63, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=185, Percent_Identity=34.0540540540541, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81327; Mature: 81327

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS50046 PHYTOCHROME_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPVSAPEIFEHTLPQHVYPQLSLSLADMVRSVPGVAKLLTSVEVGAMVPETQRFTVLTS
CCCCCCHHHHHHCCCHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEC
KSFSALVYEAEKAQLKLTFEPMAITTFLERLYQHCPAGSPLQQRITEVRERQSRKNNDAK
CCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCE
LQGQFTLLSLAAMYPGPRAEAVPLAPEVTLHPTANQERLSHQIISQLSQGVELPALLSMV
EEEHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
VEELRHLLQADRLLIYQLSPTAPSGAESHHPVSAQSGSVVHEALASSELPSVLSDQEQLW
HHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCHHHHC
GIASSESLLKYQQGYTLAIHDVLQNDSVSEPLAKVLDSIQVRALLVTPILVKSELWGLLI
CCCCCHHHHHHHCCCEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHQCLHPRQWQVQEQDLLKRMAEHVAIAIHQAALQDQVRQHKQTLDKQVEQRTQELHAAL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAQSSNQAKSDFLATMSHELRTPLTCVIGMSATLLRWSLGPLTDKQRSCLQTIHDSGEH
HHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHH
LLELINDILDFSHVQSGKATLNVSDFSLTTLVQQLLQVMRDKADAHQVQLKANLKIPPER
HHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCH
DRFIADLRRVQQILISLTDNAIKFTPMGGKVTLRVWVETNTVVFQVEDTGIGISSSQLPH
HHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEECCEEEEEEECCCCCCCCCCCHH
LFEKFQQLDGSYHRTYEGAGLGLALAQQCVTLHQGWIDVSSEEGQGSIFTVQLPNQSALF
HHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCEEEEECCCCHHHH
QQETSSQPLSAGRIVLIEGHEEDATLLCDMLTAANYQVIWMVEASAAIDQIRLLQPIAVI
HHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHHHHHE
VDAQLPAQGCLGLIRRLRALPGTDKIKIIVLTQEGISKDHQRYLSLGADAYLLKSLQPED
EECCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHCCCHHH
LLRKVNVLLKSASVL
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MMPVSAPEIFEHTLPQHVYPQLSLSLADMVRSVPGVAKLLTSVEVGAMVPETQRFTVLTS
CCCCCCHHHHHHCCCHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEC
KSFSALVYEAEKAQLKLTFEPMAITTFLERLYQHCPAGSPLQQRITEVRERQSRKNNDAK
CCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCE
LQGQFTLLSLAAMYPGPRAEAVPLAPEVTLHPTANQERLSHQIISQLSQGVELPALLSMV
EEEHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
VEELRHLLQADRLLIYQLSPTAPSGAESHHPVSAQSGSVVHEALASSELPSVLSDQEQLW
HHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCHHHHC
GIASSESLLKYQQGYTLAIHDVLQNDSVSEPLAKVLDSIQVRALLVTPILVKSELWGLLI
CCCCCHHHHHHHCCCEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHQCLHPRQWQVQEQDLLKRMAEHVAIAIHQAALQDQVRQHKQTLDKQVEQRTQELHAAL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAQSSNQAKSDFLATMSHELRTPLTCVIGMSATLLRWSLGPLTDKQRSCLQTIHDSGEH
HHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHH
LLELINDILDFSHVQSGKATLNVSDFSLTTLVQQLLQVMRDKADAHQVQLKANLKIPPER
HHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCH
DRFIADLRRVQQILISLTDNAIKFTPMGGKVTLRVWVETNTVVFQVEDTGIGISSSQLPH
HHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEECCEEEEEEECCCCCCCCCCCHH
LFEKFQQLDGSYHRTYEGAGLGLALAQQCVTLHQGWIDVSSEEGQGSIFTVQLPNQSALF
HHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCEEEEECCCCHHHH
QQETSSQPLSAGRIVLIEGHEEDATLLCDMLTAANYQVIWMVEASAAIDQIRLLQPIAVI
HHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHHHHHE
VDAQLPAQGCLGLIRRLRALPGTDKIKIIVLTQEGISKDHQRYLSLGADAYLLKSLQPED
EECCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHCCCHHH
LLRKVNVLLKSASVL
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]