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The map label for this gene is vhb [H]

Identifier: 158337527

GI number: 158337527

Start: 4433191

End: 4434207

Strand: Direct

Name: vhb [H]

Synonym: AM1_4406

Alternate gene names: 158337527

Gene position: 4433191-4434207 (Clockwise)

Preceding gene: 158337526

Following gene: 158337528

Centisome position: 68.16

GC content: 48.28

Gene sequence:

>1017_bases
ATGACCTTACAAGTTGAAATCCTTGAAAGTAGCTTTGAGAAAGTAAAACCTCAAGCTAATGAATTTGTTTCAAGTTTTTA
TAATCACTTATTCACGGATTACCCAGAGGCTCAACCTCTTTTTGAGGGAACAGACATGGAGAAGCAAGGTGGCAAGCTCT
TGCAATCTCTGGTATTGGTGATTGAGAATTTGCGCAAACCTGATGCGTTGGGTAATGCTCTCAAAGGTCTGGGAGCCCGA
CATGTGAAATATGGGGCCTTACCGGAGCATTACCCCTTGGTGGGAGCGACCTTACTGAAGACGTTTGAACAATACCTAGG
GGATGCATGGACTGAAGAGGTTCAAACAGCCTGGGTGGATGCCTACGGAGCCATTACCACCATCATGTTGGACGGTGCAG
ATTATTCAGAGGCAGATGTCCAGCTCAAACCAGAAGCGCCACCGACTGAATCCGGCTTGCAAGTTGAGCTATTGGAAACG
AGCTTTGCCCAAGTGAAGCCTGTCGCTAATGAGTTTGCGGATCGCTTTTACGAGAACCTGTTCACTGATTATCCCGCTGC
CCAACCCTTATTTGCGAATACAGATATCAAACAACAAAGCAAAAAATTGCTGCAATCCCTCGTGTTGGTTGTTGAAAATC
TGCGTAAGCCAGATGCACTAGGAGACGCCCTCACGGGACTGGGGGCTCGGCATGTGAAATATGGCGCTTTACCGGAGCAT
TACCCCTTGGTGGGTAATACCCTGCTCAAAACCTTTGAGGAATTTTTAGGGACTGCCTGGACTGATGATGTCAAACAGGC
TTGGGTCGATGCCTATGGGGCTATCAGCACCATCATGTTAGACGGTGCTGATTATTCCACAGCAGATTTAGATTTGAATT
CAGCCTCCCCCGCTGCAGCCGCCTCACCTAGCAGCTTCTCCAGTGAGGCTTCAGAGCCTGAGCGACCAACAGGATTGTTA
TTAGGGCTGGCAGGTGGCGGCATTATTGCGGTCATTATTGCCATTCTGTTGGTCTAA

Upstream 100 bases:

>100_bases
ACTGAACAGCTATTAATCCCACCTTTGAAAAAAGATTAGACTCGGTTCAATTAATCTTTTGAATTAGCCCTTGAGCCCCA
TATCTTCAATAGGTAAATCT

Downstream 100 bases:

>100_bases
ATTTTCTAGGGCAATTGTAGTGGCCAAAACGAAAAAATCTTTTTTGAGCTTATCGGCTCTATTTAATGTCAGAAATACTG
TGATTGTGCTGTGTTTAATT

Product: globin domain-containing protein

Products: @TETR01txt*tetrahydropteridine!; NO3-; NAD(P); Proton [C]

Alternate protein names: Soluble cytochrome O [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTLQVEILESSFEKVKPQANEFVSSFYNHLFTDYPEAQPLFEGTDMEKQGGKLLQSLVLVIENLRKPDALGNALKGLGAR
HVKYGALPEHYPLVGATLLKTFEQYLGDAWTEEVQTAWVDAYGAITTIMLDGADYSEADVQLKPEAPPTESGLQVELLET
SFAQVKPVANEFADRFYENLFTDYPAAQPLFANTDIKQQSKKLLQSLVLVVENLRKPDALGDALTGLGARHVKYGALPEH
YPLVGNTLLKTFEEFLGTAWTDDVKQAWVDAYGAISTIMLDGADYSTADLDLNSASPAAAASPSSFSSEASEPERPTGLL
LGLAGGGIIAVIIAILLV

Sequences:

>Translated_338_residues
MTLQVEILESSFEKVKPQANEFVSSFYNHLFTDYPEAQPLFEGTDMEKQGGKLLQSLVLVIENLRKPDALGNALKGLGAR
HVKYGALPEHYPLVGATLLKTFEQYLGDAWTEEVQTAWVDAYGAITTIMLDGADYSEADVQLKPEAPPTESGLQVELLET
SFAQVKPVANEFADRFYENLFTDYPAAQPLFANTDIKQQSKKLLQSLVLVVENLRKPDALGDALTGLGARHVKYGALPEH
YPLVGNTLLKTFEEFLGTAWTDDVKQAWVDAYGAISTIMLDGADYSTADLDLNSASPAAAASPSSFSSEASEPERPTGLL
LGLAGGGIIAVIIAILLV
>Mature_337_residues
TLQVEILESSFEKVKPQANEFVSSFYNHLFTDYPEAQPLFEGTDMEKQGGKLLQSLVLVIENLRKPDALGNALKGLGARH
VKYGALPEHYPLVGATLLKTFEQYLGDAWTEEVQTAWVDAYGAITTIMLDGADYSEADVQLKPEAPPTESGLQVELLETS
FAQVKPVANEFADRFYENLFTDYPAAQPLFANTDIKQQSKKLLQSLVLVVENLRKPDALGDALTGLGARHVKYGALPEHY
PLVGNTLLKTFEEFLGTAWTDDVKQAWVDAYGAISTIMLDGADYSTADLDLNSASPAAAASPSSFSSEASEPERPTGLLL
GLAGGGIIAVIIAILLV

Specific function: This protein functions as a terminal oxidase [H]

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the globin family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321673, Length=126, Percent_Identity=30.1587301587302, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971 [H]

Pfam domain/function: PF00042 Globin [H]

EC number: 1.5.1.34 [C]

Molecular weight: Translated: 36646; Mature: 36515

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQVEILESSFEKVKPQANEFVSSFYNHLFTDYPEAQPLFEGTDMEKQGGKLLQSLVLV
CCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
IENLRKPDALGNALKGLGARHVKYGALPEHYPLVGATLLKTFEQYLGDAWTEEVQTAWVD
HHHCCCCHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYGAITTIMLDGADYSEADVQLKPEAPPTESGLQVELLETSFAQVKPVANEFADRFYENL
HHHHHHHEEECCCCCCCCCEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
FTDYPAAQPLFANTDIKQQSKKLLQSLVLVVENLRKPDALGDALTGLGARHVKYGALPEH
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCCC
YPLVGNTLLKTFEEFLGTAWTDDVKQAWVDAYGAISTIMLDGADYSTADLDLNSASPAAA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCC
ASPSSFSSEASEPERPTGLLLGLAGGGIIAVIIAILLV
CCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHC
>Mature Secondary Structure 
TLQVEILESSFEKVKPQANEFVSSFYNHLFTDYPEAQPLFEGTDMEKQGGKLLQSLVLV
CEEEHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
IENLRKPDALGNALKGLGARHVKYGALPEHYPLVGATLLKTFEQYLGDAWTEEVQTAWVD
HHHCCCCHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYGAITTIMLDGADYSEADVQLKPEAPPTESGLQVELLETSFAQVKPVANEFADRFYENL
HHHHHHHEEECCCCCCCCCEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
FTDYPAAQPLFANTDIKQQSKKLLQSLVLVVENLRKPDALGDALTGLGARHVKYGALPEH
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCCC
YPLVGNTLLKTFEEFLGTAWTDDVKQAWVDAYGAISTIMLDGADYSTADLDLNSASPAAA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCC
ASPSSFSSEASEPERPTGLLLGLAGGGIIAVIIAILLV
CCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FAD [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dihydropteridine; 2 nitric oxide; O2; NAD(P)H [C]

Specific reaction: NAD(P)H + dihydropteridine = NAD(P)+ @TETR01.txt*tetrahydropteridine! 2 nitric oxide + 2 O2 + NAD(P)H = 2 NO3- + NAD(P) + Proton [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3067078; 3736670; 2685332; 2681149; 9115439 [H]