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The map label for this gene is steT [H]

Identifier: 158337502

GI number: 158337502

Start: 4411350

End: 4412717

Strand: Direct

Name: steT [H]

Synonym: AM1_4381

Alternate gene names: 158337502

Gene position: 4411350-4412717 (Clockwise)

Preceding gene: 158337501

Following gene: 158337503

Centisome position: 67.83

GC content: 48.32

Gene sequence:

>1368_bases
ATGACCGGATTCAATCCATCTCATTCCGTCGACAGTGCGCCTGTCGTGGCTCCAGAGACATCCAGGCAGGTCACCCTGTT
TACGGCGACTTGCTTGGTGATTGCCAACATGATTGGGATTGGGGTTTTCACCAGTCTCGGATTTCAAGTCGCAGGTATTC
AATCGGGATTTTCCTTGCTTTTTCTGTGGCTGGCAGGAGGCGTCTATGCTCTTTGTGGTGCTCTCGCCTATGGAGAACTC
GGTGCATCCATGCCTCGCTCTGGCGGTGAATACCATTTTCTCTCCCAGATTTACCATCCGGTCATTGGGTTTTTGTCCGG
TTGGGTCTCCGTCACCGTCGGATTTGCCGCTCCCATAGCTCTGATGGCCATAGCCCTGGGTACTTATTTTGCCAAAGTGT
TCCCTACGGCAGATCCCACCATCATTGGCTTAGCTGTGGTTCTTCTCGTGACCTTGATTCACTCCCAAAACCTCAAACTA
GGTAGTTCGTTTCAGCAGATCTTTACCCTGCTCAAAGTTCTGCTGATCGTGTTTCTAGTTTTAGCTGGCTTTGCGTTGGG
TACTGGCCAAGAGATCAATTTCGCACCCACCCATGCGGACATTTCTCAAATTATGAGTGCCCCCTTTGCCATTTCTTTGG
TGTATGTCACCTACTCTTATTCAGGATGGAACTCCGCAGTTTACCTGGCCAGTGAAGTTAAATCCCCGGAGAAGAACCTA
CCCCGTTCCCTATTGTTGGGGACTGCCATTGTCATGGTTTTATATCTGCTGATTAACTTCATTTTCCTCTACACCACCCC
CATCGACTTAATGGCCGGGAAGCTAGAAGTCGGCTATATTGCTGCCGATCAAATCTTTAAGGGCAATCCCATCTTGGGTT
TCCCAGGAGCTGAGCTGATGGCTCTATTTATCTCCTTGGGATTAATCTCTTCCATTAGCTCGATGGTATGGGCCGGCCCG
AGGGTAACCCAATCCATTGGAGAGGATATTCCTTTCTTCAAAATTTTGGCCAAAAAGAATCGCAGTGGCGTTCCCTACTA
TGCGCTCTTACTTCAGCTCGCTATTGTGATTGCCTTAGTGATTATGAAGCAATTTGAAACAGTGTTGACCTACTTGGAAT
TTACGCTGATCCTGTCTTCTTTTTTGACCGTGTTAGGTGTATTTGTGTCTCGCTTTCGGTTCCCAGACCTACCCCGCCCT
TACAAAACCTGGGGCTATCCCATTACCCCTTTAATCTTCCTCGCCATGAGTGTATGGGTTCTAGTGTTTTTACTCCAGCA
AAAACCGATGGAATCCTTGGCAGGCTTAGGGACGATTCTTTTAGGCCTCCCGCTCTATTTCATTGCCTCTAAGCAGAAAC
TTGCATAG

Upstream 100 bases:

>100_bases
GGATCACCGTTAACACTAGACAAACGGTGCATGGTCGGGGCAAGCAGCGTTCGCTAGCTTGAAAAAGATTTCTATATACT
GACAAATTCTTCTGATATTT

Downstream 100 bases:

>100_bases
ACATCTAAACATTATGAAAAATATGCGCTTATCTCTAATCTTAACGGCAGCCCTACTATTGGGCGGAGGACTCCAGTCCT
GTGATTCCGCTAATCAGTCC

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MTGFNPSHSVDSAPVVAPETSRQVTLFTATCLVIANMIGIGVFTSLGFQVAGIQSGFSLLFLWLAGGVYALCGALAYGEL
GASMPRSGGEYHFLSQIYHPVIGFLSGWVSVTVGFAAPIALMAIALGTYFAKVFPTADPTIIGLAVVLLVTLIHSQNLKL
GSSFQQIFTLLKVLLIVFLVLAGFALGTGQEINFAPTHADISQIMSAPFAISLVYVTYSYSGWNSAVYLASEVKSPEKNL
PRSLLLGTAIVMVLYLLINFIFLYTTPIDLMAGKLEVGYIAADQIFKGNPILGFPGAELMALFISLGLISSISSMVWAGP
RVTQSIGEDIPFFKILAKKNRSGVPYYALLLQLAIVIALVIMKQFETVLTYLEFTLILSSFLTVLGVFVSRFRFPDLPRP
YKTWGYPITPLIFLAMSVWVLVFLLQQKPMESLAGLGTILLGLPLYFIASKQKLA

Sequences:

>Translated_455_residues
MTGFNPSHSVDSAPVVAPETSRQVTLFTATCLVIANMIGIGVFTSLGFQVAGIQSGFSLLFLWLAGGVYALCGALAYGEL
GASMPRSGGEYHFLSQIYHPVIGFLSGWVSVTVGFAAPIALMAIALGTYFAKVFPTADPTIIGLAVVLLVTLIHSQNLKL
GSSFQQIFTLLKVLLIVFLVLAGFALGTGQEINFAPTHADISQIMSAPFAISLVYVTYSYSGWNSAVYLASEVKSPEKNL
PRSLLLGTAIVMVLYLLINFIFLYTTPIDLMAGKLEVGYIAADQIFKGNPILGFPGAELMALFISLGLISSISSMVWAGP
RVTQSIGEDIPFFKILAKKNRSGVPYYALLLQLAIVIALVIMKQFETVLTYLEFTLILSSFLTVLGVFVSRFRFPDLPRP
YKTWGYPITPLIFLAMSVWVLVFLLQQKPMESLAGLGTILLGLPLYFIASKQKLA
>Mature_454_residues
TGFNPSHSVDSAPVVAPETSRQVTLFTATCLVIANMIGIGVFTSLGFQVAGIQSGFSLLFLWLAGGVYALCGALAYGELG
ASMPRSGGEYHFLSQIYHPVIGFLSGWVSVTVGFAAPIALMAIALGTYFAKVFPTADPTIIGLAVVLLVTLIHSQNLKLG
SSFQQIFTLLKVLLIVFLVLAGFALGTGQEINFAPTHADISQIMSAPFAISLVYVTYSYSGWNSAVYLASEVKSPEKNLP
RSLLLGTAIVMVLYLLINFIFLYTTPIDLMAGKLEVGYIAADQIFKGNPILGFPGAELMALFISLGLISSISSMVWAGPR
VTQSIGEDIPFFKILAKKNRSGVPYYALLLQLAIVIALVIMKQFETVLTYLEFTLILSSFLTVLGVFVSRFRFPDLPRPY
KTWGYPITPLIFLAMSVWVLVFLLQQKPMESLAGLGTILLGLPLYFIASKQKLA

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI115648063, Length=456, Percent_Identity=28.7280701754386, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI115648022, Length=456, Percent_Identity=28.7280701754386, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI186910308, Length=438, Percent_Identity=27.1689497716895, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI186910306, Length=438, Percent_Identity=27.1689497716895, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI186910304, Length=438, Percent_Identity=27.1689497716895, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI187423910, Length=453, Percent_Identity=25.3863134657837, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI7657591, Length=453, Percent_Identity=25.3863134657837, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI33286428, Length=440, Percent_Identity=26.1363636363636, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI7657683, Length=399, Percent_Identity=25.31328320802, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI71979932, Length=444, Percent_Identity=25.6756756756757, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI9790235, Length=402, Percent_Identity=26.3681592039801, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI71999149, Length=393, Percent_Identity=25.9541984732824, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI33286430, Length=242, Percent_Identity=26.0330578512397, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI87082250, Length=443, Percent_Identity=24.1534988713318, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788480, Length=468, Percent_Identity=24.3589743589744, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17540018, Length=469, Percent_Identity=25.5863539445629, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI32566699, Length=423, Percent_Identity=27.6595744680851, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71993915, Length=476, Percent_Identity=25.8403361344538, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71995388, Length=472, Percent_Identity=25.8474576271186, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71995382, Length=479, Percent_Identity=26.5135699373695, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17568033, Length=466, Percent_Identity=24.2489270386266, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71982612, Length=454, Percent_Identity=23.3480176211454, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71982608, Length=454, Percent_Identity=23.3480176211454, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71990446, Length=451, Percent_Identity=23.2815964523282, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193208714, Length=421, Percent_Identity=23.0403800475059, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32566695, Length=421, Percent_Identity=23.0403800475059, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71982623, Length=254, Percent_Identity=27.1653543307087, Blast_Score=82, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6321492, Length=366, Percent_Identity=25.9562841530055, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321751, Length=416, Percent_Identity=24.0384615384615, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45550968, Length=465, Percent_Identity=25.5913978494624, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19921172, Length=465, Percent_Identity=25.5913978494624, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24641993, Length=396, Percent_Identity=29.040404040404, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24641995, Length=396, Percent_Identity=29.040404040404, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24651635, Length=444, Percent_Identity=25.9009009009009, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24651633, Length=444, Percent_Identity=25.9009009009009, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI221331183, Length=451, Percent_Identity=25.2771618625277, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17647653, Length=451, Percent_Identity=25.2771618625277, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24664379, Length=451, Percent_Identity=25.2771618625277, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21357367, Length=459, Percent_Identity=22.6579520697168, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49236; Mature: 49105

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGFNPSHSVDSAPVVAPETSRQVTLFTATCLVIANMIGIGVFTSLGFQVAGIQSGFSLL
CCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHH
FLWLAGGVYALCGALAYGELGASMPRSGGEYHFLSQIYHPVIGFLSGWVSVTVGFAAPIA
HHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMAIALGTYFAKVFPTADPTIIGLAVVLLVTLIHSQNLKLGSSFQQIFTLLKVLLIVFLV
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LAGFALGTGQEINFAPTHADISQIMSAPFAISLVYVTYSYSGWNSAVYLASEVKSPEKNL
HHHHHCCCCCCCCCCCCHHHHHHHHCCCHHEEEEEEEEEECCCCCCEEEHHHHCCCHHHC
PRSLLLGTAIVMVLYLLINFIFLYTTPIDLMAGKLEVGYIAADQIFKGNPILGFPGAELM
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEEEEHHHEECCCCCCCCCCHHHH
ALFISLGLISSISSMVWAGPRVTQSIGEDIPFFKILAKKNRSGVPYYALLLQLAIVIALV
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IMKQFETVLTYLEFTLILSSFLTVLGVFVSRFRFPDLPRPYKTWGYPITPLIFLAMSVWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LVFLLQQKPMESLAGLGTILLGLPLYFIASKQKLA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHCCC
>Mature Secondary Structure 
TGFNPSHSVDSAPVVAPETSRQVTLFTATCLVIANMIGIGVFTSLGFQVAGIQSGFSLL
CCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHH
FLWLAGGVYALCGALAYGELGASMPRSGGEYHFLSQIYHPVIGFLSGWVSVTVGFAAPIA
HHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMAIALGTYFAKVFPTADPTIIGLAVVLLVTLIHSQNLKLGSSFQQIFTLLKVLLIVFLV
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LAGFALGTGQEINFAPTHADISQIMSAPFAISLVYVTYSYSGWNSAVYLASEVKSPEKNL
HHHHHCCCCCCCCCCCCHHHHHHHHCCCHHEEEEEEEEEECCCCCCEEEHHHHCCCHHHC
PRSLLLGTAIVMVLYLLINFIFLYTTPIDLMAGKLEVGYIAADQIFKGNPILGFPGAELM
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEEEEHHHEECCCCCCCCCCHHHH
ALFISLGLISSISSMVWAGPRVTQSIGEDIPFFKILAKKNRSGVPYYALLLQLAIVIALV
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IMKQFETVLTYLEFTLILSSFLTVLGVFVSRFRFPDLPRPYKTWGYPITPLIFLAMSVWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LVFLLQQKPMESLAGLGTILLGLPLYFIASKQKLA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]