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The map label for this gene is yafC [H]

Identifier: 158337296

GI number: 158337296

Start: 4203164

End: 4204072

Strand: Direct

Name: yafC [H]

Synonym: AM1_4174

Alternate gene names: 158337296

Gene position: 4203164-4204072 (Clockwise)

Preceding gene: 158337292

Following gene: 158337298

Centisome position: 64.63

GC content: 50.39

Gene sequence:

>909_bases
ATGGATATATCGGTACTGAAGTTGTTTGTGGATGTCGTTCGGCAGGGCAGTTTTGCGGGAGCCGCTCGAGATCGCAACAT
TGATCCATCCTCGGTATCGCGAGCCATTGCTGGACTGGAGAAGGAACTCGATCTGCGGCTTCTACAGCGGACGACGCGCC
AGCTCTCCCTGACGGAAGCGGGAAAAACCTATTTTGAACGAATTGAACCTTTGATCGAAGAGCTACAACAGGCGTCGGAA
ATTGCAGCAGATGTGGTGGGGCAACCCAAGGGACAGTTAAGGGTAACGGTATCCGCCTCTTTTGGCTTGAAGTGTATCGT
GCCCCTCTTGCCCCAGTTTGAGCAACTGTATCCAGACCTGACGGTCAATTTATTGTTTTCAGATGCCGTTGAAGATTTGT
TGCTCAACCGGATTGATGTCGCGATTCGCCTGGGGCTGCTCCGGGATTCTACCTTGATTGCTCAGCAGTTGATGCAGACT
CGATATCGGGTTTGTGCCAGTCCAGATTATCTAAAGCAGTCGCCCCCGATTGCCGTTCCCGAGGATATTGCCGACCATAA
TTGTTTGCGGTTTCCATTGGCAGGGTTTCAGTCTCAATGGTTGTTCAAAGATGCCCAAGGGACCTTAACGGAAGTGCCGA
TTCATGGCAACACGGTGATTTCCAATGGTATTGCTCTGCAGCAATGTGTGATCGCAAATATGGGATTGGCCCTACTCCCC
AACTGGCTGATCAATGAAGACTTACGCACAGGTACCCTCGTAGATGTTCTGCCAGCCTATGAGGTCACAGGTACGGACTT
TAGTACTGCCGCGTGGTTTGTCTATCCTTCTAGATGCTATGTTCCCCTCAAGCTCAGAGTGTTCATTGAATTCTTTAAGC
AGAACGTTCCTCGTTTGGTGATGCCTTGA

Upstream 100 bases:

>100_bases
GAACAATAAAGCCCCATGAGTGCATGATACTCGTGCATTATATTCATGAATACAACAAGAATTCATGCAAGAATTTCTGG
GCGTCAAGGATAGGACCTCA

Downstream 100 bases:

>100_bases
TGTTCCCGATTGCGTTTGTCTTGGAGACAGGGGGTTACTTACCGTTCTAGGAGCGTCCGTTCTGTTGTCGCTTCATGGGA
AAGAACGACTGCTCGCTCAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MDISVLKLFVDVVRQGSFAGAARDRNIDPSSVSRAIAGLEKELDLRLLQRTTRQLSLTEAGKTYFERIEPLIEELQQASE
IAADVVGQPKGQLRVTVSASFGLKCIVPLLPQFEQLYPDLTVNLLFSDAVEDLLLNRIDVAIRLGLLRDSTLIAQQLMQT
RYRVCASPDYLKQSPPIAVPEDIADHNCLRFPLAGFQSQWLFKDAQGTLTEVPIHGNTVISNGIALQQCVIANMGLALLP
NWLINEDLRTGTLVDVLPAYEVTGTDFSTAAWFVYPSRCYVPLKLRVFIEFFKQNVPRLVMP

Sequences:

>Translated_302_residues
MDISVLKLFVDVVRQGSFAGAARDRNIDPSSVSRAIAGLEKELDLRLLQRTTRQLSLTEAGKTYFERIEPLIEELQQASE
IAADVVGQPKGQLRVTVSASFGLKCIVPLLPQFEQLYPDLTVNLLFSDAVEDLLLNRIDVAIRLGLLRDSTLIAQQLMQT
RYRVCASPDYLKQSPPIAVPEDIADHNCLRFPLAGFQSQWLFKDAQGTLTEVPIHGNTVISNGIALQQCVIANMGLALLP
NWLINEDLRTGTLVDVLPAYEVTGTDFSTAAWFVYPSRCYVPLKLRVFIEFFKQNVPRLVMP
>Mature_302_residues
MDISVLKLFVDVVRQGSFAGAARDRNIDPSSVSRAIAGLEKELDLRLLQRTTRQLSLTEAGKTYFERIEPLIEELQQASE
IAADVVGQPKGQLRVTVSASFGLKCIVPLLPQFEQLYPDLTVNLLFSDAVEDLLLNRIDVAIRLGLLRDSTLIAQQLMQT
RYRVCASPDYLKQSPPIAVPEDIADHNCLRFPLAGFQSQWLFKDAQGTLTEVPIHGNTVISNGIALQQCVIANMGLALLP
NWLINEDLRTGTLVDVLPAYEVTGTDFSTAAWFVYPSRCYVPLKLRVFIEFFKQNVPRLVMP

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=34.020618556701, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1789639, Length=285, Percent_Identity=30.8771929824561, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI87081978, Length=294, Percent_Identity=30.2721088435374, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787128, Length=296, Percent_Identity=29.0540540540541, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789440, Length=291, Percent_Identity=29.2096219931272, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI145693193, Length=306, Percent_Identity=29.7385620915033, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1789173, Length=257, Percent_Identity=30.7392996108949, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787589, Length=296, Percent_Identity=26.3513513513513, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1786448, Length=286, Percent_Identity=24.8251748251748, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787601, Length=125, Percent_Identity=30.4, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790011, Length=261, Percent_Identity=26.0536398467433, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI157672245, Length=182, Percent_Identity=28.021978021978, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082132, Length=275, Percent_Identity=28.7272727272727, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=200, Percent_Identity=23, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788706, Length=172, Percent_Identity=29.6511627906977, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786508, Length=258, Percent_Identity=24.4186046511628, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790262, Length=260, Percent_Identity=22.6923076923077, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33687; Mature: 33687

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISVLKLFVDVVRQGSFAGAARDRNIDPSSVSRAIAGLEKELDLRLLQRTTRQLSLTEA
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKTYFERIEPLIEELQQASEIAADVVGQPKGQLRVTVSASFGLKCIVPLLPQFEQLYPDL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEHHHHHHHHHHHCCCC
TVNLLFSDAVEDLLLNRIDVAIRLGLLRDSTLIAQQLMQTRYRVCASPDYLKQSPPIAVP
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
EDIADHNCLRFPLAGFQSQWLFKDAQGTLTEVPIHGNTVISNGIALQQCVIANMGLALLP
HHHCCCCEEECCCCCCCCCCEEECCCCCEEEECCCCCEEECCCHHHHHHHHHHCCHHHCC
NWLINEDLRTGTLVDVLPAYEVTGTDFSTAAWFVYPSRCYVPLKLRVFIEFFKQNVPRLV
HHHHCCCCCCCCHHHHHCCCEECCCCCCCEEEEEECCCEEEEHHHHHHHHHHHCCCCCCC
MP
CC
>Mature Secondary Structure
MDISVLKLFVDVVRQGSFAGAARDRNIDPSSVSRAIAGLEKELDLRLLQRTTRQLSLTEA
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKTYFERIEPLIEELQQASEIAADVVGQPKGQLRVTVSASFGLKCIVPLLPQFEQLYPDL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEHHHHHHHHHHHCCCC
TVNLLFSDAVEDLLLNRIDVAIRLGLLRDSTLIAQQLMQTRYRVCASPDYLKQSPPIAVP
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
EDIADHNCLRFPLAGFQSQWLFKDAQGTLTEVPIHGNTVISNGIALQQCVIANMGLALLP
HHHCCCCEEECCCCCCCCCCEEECCCCCEEEECCCCCEEECCCHHHHHHHHHHCCHHHCC
NWLINEDLRTGTLVDVLPAYEVTGTDFSTAAWFVYPSRCYVPLKLRVFIEFFKQNVPRLV
HHHHCCCCCCCCHHHHHCCCEECCCCCCCEEEEEECCCEEEEHHHHHHHHHHHCCCCCCC
MP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]