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The map label for this gene is ffh [H]

Identifier: 158337260

GI number: 158337260

Start: 4174027

End: 4175457

Strand: Direct

Name: ffh [H]

Synonym: AM1_4137

Alternate gene names: 158337260

Gene position: 4174027-4175457 (Clockwise)

Preceding gene: 158337259

Following gene: 158337263

Centisome position: 64.18

GC content: 53.04

Gene sequence:

>1431_bases
ATGTTTGAAGCCCTATCAGATCGGCTTGAATCTGCCTGGAAAACCCTCCGGGGTCAAGACAAAATCTCGGAGTCGAACAT
TCAGGACGCCCTACGAGAAGTCCGACGGGCGCTGCTGGAAGCCGATGTCAACTTGCAGGTTGTCAAAGATTTTATCGAAG
AAGTACGGGAGTCGGCCTTAGGGGCCGAGGTGATCACGGGGGTGCAGCCGGATCAGCAATTTATCAAGATTGTCCATGAT
CAGCTGGTCGAGATTATGGGGGCAACCAATGAGCCCTTAGCGGAGTCCAACAAGCCGCCCACCGTGATTTTGATGGCGGG
TTTGCAGGGTACTGGTAAAACCACGGCAACGGCTAAACTTGCCCTGCATTTGCGCAAACAGGAGCAGACGTCTCTCCTGG
TGGCCACGGATATCTATCGGCCAGCGGCCATCGACCAGTTGGTGACTTTGGGTGAACAGATTGATGTCCCGGTTTTTCAG
TTAGGGACGGATGCCAACCCGGTCGAAATTGCCCGCCAAGGTCTGGCGGCAGCCCGGGAGCAAAATGTAGATACGGTGAT
TGTGGATACGGCTGGTCGTCTGCAAATTGACCCCGAAATGATGTCTGAGCTGGCGGACATTAAAAAAGCCATCAAACCAG
ACGAGACCTTACTGGTCGTCGATGCCATGACGGGTCAGGAAGCGGCCAATCTGACCCAGACCTTCCACGACCAGATCGGC
ATTACTGGAGCCATTCTGACCAAGATGGATGGCGACACTCGTGGGGGTGCAGCCCTCTCGATTCGTCAAATTTCCGGTAA
GCCCATTAAATTTGTGGGGGTTGGGGAAAAAGTTGAGGCATTACAGCCTTTCTATCCGGATCGCATGGCATCCCGCATTT
TAGGGATGGGGGATGTGCTGACGCTGGTGGAAAAAGCTCAGGAAGAGTTTGACATCGCCGATGCGGAGAAGATGCAGAAG
AAGATCATGGAGGCTCAGTTTGACTTCACTGATTTTCTCAAGCAAATGCGATTGCTCAAGAATATGGGCTCTCTCGGTGG
GGTGATGAAGCTCATCCCCGGCATGAATAAGATCTCCAACTCTCAGCTCCAGGAAGGGGAAACCAAACTGAAGCAGACGG
AAGCAATGATCAACTCCATGACCAAGGAGGAGCGCAAAAATCCCCAGTTACTCTCTAACTCCCCTAGCCGTCGTCGCCGA
ATCGCCAAGGGGTCTGGCTATACGCAAAATGATGTCGGTAAGTTAGTGACGGAATTCCAGCGGATGCGATCGATGATGCA
GCAGATGGGGCAAGGACAAATGCCCGGCATGTCTCCTGCGGGAGGAGGCAATCCGATGATGGGCGGTGGCCGACCTAGTC
GCGGTGGCTGGCGTGGCGGGATAGGCAAGAAGAAGAAAAATAAAAAGAGAAAAGGATTTGGTGATTTGTAA

Upstream 100 bases:

>100_bases
CTACCGTAACGAGGGCTCCTTCTTCTGCTACGGCTTCTTCTAAGTAGCGGCGTCTACCGCTCCTATGTCAAAATAATTAT
CTGCAAATAGGTAACCCGCT

Downstream 100 bases:

>100_bases
GCGATCGCAAATCTGCATTGCATCTGCGTAAGTCGCTAACGCACCCTGCTGATATGTCCCAATTCCTGTGCGTTAGGTTG
GTTTGGGCGTGGAGAGGCCG

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MFEALSDRLESAWKTLRGQDKISESNIQDALREVRRALLEADVNLQVVKDFIEEVRESALGAEVITGVQPDQQFIKIVHD
QLVEIMGATNEPLAESNKPPTVILMAGLQGTGKTTATAKLALHLRKQEQTSLLVATDIYRPAAIDQLVTLGEQIDVPVFQ
LGTDANPVEIARQGLAAAREQNVDTVIVDTAGRLQIDPEMMSELADIKKAIKPDETLLVVDAMTGQEAANLTQTFHDQIG
ITGAILTKMDGDTRGGAALSIRQISGKPIKFVGVGEKVEALQPFYPDRMASRILGMGDVLTLVEKAQEEFDIADAEKMQK
KIMEAQFDFTDFLKQMRLLKNMGSLGGVMKLIPGMNKISNSQLQEGETKLKQTEAMINSMTKEERKNPQLLSNSPSRRRR
IAKGSGYTQNDVGKLVTEFQRMRSMMQQMGQGQMPGMSPAGGGNPMMGGGRPSRGGWRGGIGKKKKNKKRKGFGDL

Sequences:

>Translated_476_residues
MFEALSDRLESAWKTLRGQDKISESNIQDALREVRRALLEADVNLQVVKDFIEEVRESALGAEVITGVQPDQQFIKIVHD
QLVEIMGATNEPLAESNKPPTVILMAGLQGTGKTTATAKLALHLRKQEQTSLLVATDIYRPAAIDQLVTLGEQIDVPVFQ
LGTDANPVEIARQGLAAAREQNVDTVIVDTAGRLQIDPEMMSELADIKKAIKPDETLLVVDAMTGQEAANLTQTFHDQIG
ITGAILTKMDGDTRGGAALSIRQISGKPIKFVGVGEKVEALQPFYPDRMASRILGMGDVLTLVEKAQEEFDIADAEKMQK
KIMEAQFDFTDFLKQMRLLKNMGSLGGVMKLIPGMNKISNSQLQEGETKLKQTEAMINSMTKEERKNPQLLSNSPSRRRR
IAKGSGYTQNDVGKLVTEFQRMRSMMQQMGQGQMPGMSPAGGGNPMMGGGRPSRGGWRGGIGKKKKNKKRKGFGDL
>Mature_476_residues
MFEALSDRLESAWKTLRGQDKISESNIQDALREVRRALLEADVNLQVVKDFIEEVRESALGAEVITGVQPDQQFIKIVHD
QLVEIMGATNEPLAESNKPPTVILMAGLQGTGKTTATAKLALHLRKQEQTSLLVATDIYRPAAIDQLVTLGEQIDVPVFQ
LGTDANPVEIARQGLAAAREQNVDTVIVDTAGRLQIDPEMMSELADIKKAIKPDETLLVVDAMTGQEAANLTQTFHDQIG
ITGAILTKMDGDTRGGAALSIRQISGKPIKFVGVGEKVEALQPFYPDRMASRILGMGDVLTLVEKAQEEFDIADAEKMQK
KIMEAQFDFTDFLKQMRLLKNMGSLGGVMKLIPGMNKISNSQLQEGETKLKQTEAMINSMTKEERKNPQLLSNSPSRRRR
IAKGSGYTQNDVGKLVTEFQRMRSMMQQMGQGQMPGMSPAGGGNPMMGGGRPSRGGWRGGIGKKKKNKKRKGFGDL

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:
GO:0000166: Signal recognition particle protein
GO:0005525: Signal recognition particle protein
GO:0006614: Signal recognition particle protein
GO:0008312: Signal recognition particle protein
GO:0017111: Signal recognition particle protein
GO:0048500: Signal recognition particle protein

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=431, Percent_Identity=31.0904872389791, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI226371618, Length=373, Percent_Identity=30.2949061662198, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI89061728, Length=146, Percent_Identity=35.6164383561644, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI23308697, Length=300, Percent_Identity=29, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI295424842, Length=300, Percent_Identity=29, Blast_Score=108, Evalue=9e-24,
Organism=Escherichia coli, GI1788963, Length=426, Percent_Identity=50, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1789874, Length=269, Percent_Identity=35.3159851301115, Blast_Score=167, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17539958, Length=431, Percent_Identity=27.1461716937355, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI193206261, Length=298, Percent_Identity=29.1946308724832, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325345, Length=466, Percent_Identity=33.0472103004292, Blast_Score=235, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6320498, Length=313, Percent_Identity=26.1980830670927, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17647949, Length=431, Percent_Identity=30.6264501160093, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24641198, Length=305, Percent_Identity=28.1967213114754, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 52135; Mature: 52135

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEALSDRLESAWKTLRGQDKISESNIQDALREVRRALLEADVNLQVVKDFIEEVRESAL
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GAEVITGVQPDQQFIKIVHDQLVEIMGATNEPLAESNKPPTVILMAGLQGTGKTTATAKL
CHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHH
ALHLRKQEQTSLLVATDIYRPAAIDQLVTLGEQIDVPVFQLGTDANPVEIARQGLAAARE
HHHHHHHHHCCEEEEHHCCCHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHH
QNVDTVIVDTAGRLQIDPEMMSELADIKKAIKPDETLLVVDAMTGQEAANLTQTFHDQIG
CCCCEEEEECCCCEEECHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
ITGAILTKMDGDTRGGAALSIRQISGKPIKFVGVGEKVEALQPFYPDRMASRILGMGDVL
CCHHHHEECCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHCCCCHHHHHHHHHCCHHHH
TLVEKAQEEFDIADAEKMQKKIMEAQFDFTDFLKQMRLLKNMGSLGGVMKLIPGMNKISN
HHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCH
SQLQEGETKLKQTEAMINSMTKEERKNPQLLSNSPSRRRRIAKGSGYTQNDVGKLVTEFQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHH
RMRSMMQQMGQGQMPGMSPAGGGNPMMGGGRPSRGGWRGGIGKKKKNKKRKGFGDL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MFEALSDRLESAWKTLRGQDKISESNIQDALREVRRALLEADVNLQVVKDFIEEVRESAL
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GAEVITGVQPDQQFIKIVHDQLVEIMGATNEPLAESNKPPTVILMAGLQGTGKTTATAKL
CHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHH
ALHLRKQEQTSLLVATDIYRPAAIDQLVTLGEQIDVPVFQLGTDANPVEIARQGLAAARE
HHHHHHHHHCCEEEEHHCCCHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHH
QNVDTVIVDTAGRLQIDPEMMSELADIKKAIKPDETLLVVDAMTGQEAANLTQTFHDQIG
CCCCEEEEECCCCEEECHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
ITGAILTKMDGDTRGGAALSIRQISGKPIKFVGVGEKVEALQPFYPDRMASRILGMGDVL
CCHHHHEECCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHCCCCHHHHHHHHHCCHHHH
TLVEKAQEEFDIADAEKMQKKIMEAQFDFTDFLKQMRLLKNMGSLGGVMKLIPGMNKISN
HHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCH
SQLQEGETKLKQTEAMINSMTKEERKNPQLLSNSPSRRRRIAKGSGYTQNDVGKLVTEFQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHH
RMRSMMQQMGQGQMPGMSPAGGGNPMMGGGRPSRGGWRGGIGKKKKNKKRKGFGDL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]