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The map label for this gene is gntK [H]

Identifier: 158337217

GI number: 158337217

Start: 4137068

End: 4137583

Strand: Reverse

Name: gntK [H]

Synonym: AM1_4094

Alternate gene names: 158337217

Gene position: 4137583-4137068 (Counterclockwise)

Preceding gene: 158337218

Following gene: 158337216

Centisome position: 63.62

GC content: 51.55

Gene sequence:

>516_bases
ATGATAGGGGTTGCGGGTTCAGGTAAAACTACCATAGGCCGGTTATTCGCGGCCCGTTTAGAGTGTGATTTTTTAGAAGG
CGATCTACGCCATCCTGTGCGTAACATCCAAAAGATGGCTGCGCAAAAACCACTGACCGATGCGGATCGACAGATGTGGC
TGGATGAGATCGCAGATGATATTCGCTGGGCCATTGATCTAAAGCGCGAAACCGTCCTCACCTGTTCTGCCCTTAAGCAA
GCGCATCGACAGCAATTAATGGCTTTGGGCTCGGTACAGCTTGTCTGGTTAGAAGTATCAGAATCTGAGCTGCTTCAGCG
TTTGACTCAGCGAGAGAACCACTACATGCAGGCCAGGCTCTTAGCCAGTCAGCTCGATGCCTTTGAACCTATTGGCTCTG
AAGAATCCATTCTGACCGTTGATGCGACTCAGCCTCCGGCTTGGGTCGTTGAGCAAATCTGGCGGCAAGCCCTTCACTGT
TATCCCAAATTGAACCGAGTCTGGTGGGAGCGCTAG

Upstream 100 bases:

>100_bases
TTGCTTATCCATTGTCTCCCCTGAAACTTTATCAATCCTGAATAGCCATTCAATATCGAGGTGGATCATGATGACATGTG
ATATTCCTCTTATCTGGATC

Downstream 100 bases:

>100_bases
TTGATTGTAGACCAGGCAACCAGGGATACTGCTGATAGGGATATTCCCTCCATCCGCTTATTCTCAAAGGACATTGCCTG
TGACTCTGCCTCAACCCCTT

Product: gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase 1 [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MIGVAGSGKTTIGRLFAARLECDFLEGDLRHPVRNIQKMAAQKPLTDADRQMWLDEIADDIRWAIDLKRETVLTCSALKQ
AHRQQLMALGSVQLVWLEVSESELLQRLTQRENHYMQARLLASQLDAFEPIGSEESILTVDATQPPAWVVEQIWRQALHC
YPKLNRVWWER

Sequences:

>Translated_171_residues
MIGVAGSGKTTIGRLFAARLECDFLEGDLRHPVRNIQKMAAQKPLTDADRQMWLDEIADDIRWAIDLKRETVLTCSALKQ
AHRQQLMALGSVQLVWLEVSESELLQRLTQRENHYMQARLLASQLDAFEPIGSEESILTVDATQPPAWVVEQIWRQALHC
YPKLNRVWWER
>Mature_171_residues
MIGVAGSGKTTIGRLFAARLECDFLEGDLRHPVRNIQKMAAQKPLTDADRQMWLDEIADDIRWAIDLKRETVLTCSALKQ
AHRQQLMALGSVQLVWLEVSESELLQRLTQRENHYMQARLLASQLDAFEPIGSEESILTVDATQPPAWVVEQIWRQALHC
YPKLNRVWWER

Specific function: Gluconate utilization system GNT-II. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:
GO:0004765: Gluconate kinase
GO:0005524: Gluconate kinase
GO:0005975: Gluconate kinase
GO:0016301: Gluconate kinase
GO:0016310: Gluconate kinase

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=172, Percent_Identity=32.5581395348837, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1790719, Length=162, Percent_Identity=39.5061728395062, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082265, Length=153, Percent_Identity=35.2941176470588, Blast_Score=97, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25146487, Length=151, Percent_Identity=37.0860927152318, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320454, Length=135, Percent_Identity=31.8518518518519, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 19720; Mature: 19720

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGVAGSGKTTIGRLFAARLECDFLEGDLRHPVRNIQKMAAQKPLTDADRQMWLDEIADD
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IRWAIDLKRETVLTCSALKQAHRQQLMALGSVQLVWLEVSESELLQRLTQRENHYMQARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHH
LASQLDAFEPIGSEESILTVDATQPPAWVVEQIWRQALHCYPKLNRVWWER
HHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIGVAGSGKTTIGRLFAARLECDFLEGDLRHPVRNIQKMAAQKPLTDADRQMWLDEIADD
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IRWAIDLKRETVLTCSALKQAHRQQLMALGSVQLVWLEVSESELLQRLTQRENHYMQARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHH
LASQLDAFEPIGSEESILTVDATQPPAWVVEQIWRQALHCYPKLNRVWWER
HHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]