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The map label for this gene is cysS [H]

Identifier: 158337192

GI number: 158337192

Start: 4114929

End: 4116443

Strand: Direct

Name: cysS [H]

Synonym: AM1_4070

Alternate gene names: 158337192

Gene position: 4114929-4116443 (Clockwise)

Preceding gene: 158337188

Following gene: 158337195

Centisome position: 63.27

GC content: 51.42

Gene sequence:

>1515_bases
ATGCCCCTGCAAATTTACAACACCCTGAGTCGGACCAAAGAGCCGTTTACAACCCTCGAAGCTGGCAAAGTGCAGTTCTA
CTGCTGTGGGGTGACGGTCTATGACTATTGTCATTTGGGCCATGCTCGGTCTTATATTGTTTGGGATATTGTTCGGCGGT
ATCTGCAGTGGCGGGGATATGACGTTACCTATGTGCAGAACTACACGGATATTGACGATAAGATTCTCAAGCGGGCGGCA
GAGACAGGGCAAGATTGGCAGGCTGTAACCCAGACCTTTATCCAGGCCTATGAAGCAGATATGGCTCGCCTCAATATCTT
GGCAGCCGATGCTTATCCCAAAGCCACTGAATCGATACCGGCCATCATTAATCTGATCCGAGACCTCGAAACAAGGGGGG
TGGCTTATGCTGCCCAAGGCGATGTCTACTTTGCCGTTGAAAGGTTTCCAGGTTATGGAAAACTCTCTGGACGATTGCTC
GATCAGATGGAAGCAGGGGCCAGCGGTCGCGTCGAACAGCTTGAACCCGCTGAGCAAAAGAAACGCCATCCCCTAGATTT
CGCTCTGTGGAAAGCCACTAAACCTGGCGAACCGAGCTGGGACTCTCCCTGGGGACCTGGGCGTCCCGGATGGCATATTG
AGTGCTCGGCCATGGTGAATCAATGCTTAGGTGCTGAAATTGATATCCATGCGGGGGGCTCAGATTTAGTTTTTCCCCAC
CATGAGAATGAGATTGCCCAATCGGAAGCGGGTTTAACCCCCCGACTAGCCCGCTACTGGATGCATAACGGGTTTGTGAA
TGTTGGCGGGGAAAAGATGTCTAAGTCCCTGGGGAACTTCACGACCATTCGCCAGCTTTTGGATACACCCTTGCCGATTT
TGGCAGGGAAAACCCTGCATCCTATGGCTTTAAGACTGTTTGTTTTGCAAGCCCAGTATCGCAAGCCGATTGATTTTACC
GATGATGCGATCGCAGCCGCGCAGCAAAGTTGGCAAACTCTGAAAGAGGGGCTGCTGTTTGGCTATGACTACGGGGCTCA
ACTGCAATGGTCAGACTATACCGATCCAGATTTTGGCAATCCCGCCAATATGCGAATTCCAGATCCGAATGTTGCGGTTC
AGCGGTTTCAACTCGCCATGGATGATGACTTTAATTCGCCCAGTGGATTAGTTGTCTTATTCGAACTGGCTAAGGATTTA
CGCAAAGCCGGTAATATTCTCAGTCATCAAGGCGAAACGTCTACCACGAGTGAACAGCTTCGAGAGCAGTGGCAAACTTT
AGTCTGCTTAGCCCAGGTATTGGGCCTGGAGGCTCAACCTGACTCTGATGCAGCCTCCACAGATTCGGAAGATGGCCTCA
GTGAGCAAGCGATTGAAGCCTTGATTGAGGAGCGACAGGCGGCTCGCCAGGCTAAGAACTATGCCGAAAGCGATCGAATT
CGAGATCAGCTCAAAGCAGAAGGCATTACCCTAATCGATCAGGCTGGTGGGGTCACTCGGTGGTTGCGGGAATAA

Upstream 100 bases:

>100_bases
ATTTGCGCCTAATTAATCTAAAGACTTGTGGGTCTCTAGTTCTTGCTTTTCTCTCCCTGTATTCTTTGAGTCTATTTTGT
AGTTTGAAAGTGTCTTGATC

Downstream 100 bases:

>100_bases
ACCCTTCTTCTTGAGGCTTCGTGCCAATGATGGTGCGGTGGCGTGGATCGCTTGCCGTGGTGACAGTATGTTCAAAGCCA
GCTGCTGTTAACGCAGACTC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MPLQIYNTLSRTKEPFTTLEAGKVQFYCCGVTVYDYCHLGHARSYIVWDIVRRYLQWRGYDVTYVQNYTDIDDKILKRAA
ETGQDWQAVTQTFIQAYEADMARLNILAADAYPKATESIPAIINLIRDLETRGVAYAAQGDVYFAVERFPGYGKLSGRLL
DQMEAGASGRVEQLEPAEQKKRHPLDFALWKATKPGEPSWDSPWGPGRPGWHIECSAMVNQCLGAEIDIHAGGSDLVFPH
HENEIAQSEAGLTPRLARYWMHNGFVNVGGEKMSKSLGNFTTIRQLLDTPLPILAGKTLHPMALRLFVLQAQYRKPIDFT
DDAIAAAQQSWQTLKEGLLFGYDYGAQLQWSDYTDPDFGNPANMRIPDPNVAVQRFQLAMDDDFNSPSGLVVLFELAKDL
RKAGNILSHQGETSTTSEQLREQWQTLVCLAQVLGLEAQPDSDAASTDSEDGLSEQAIEALIEERQAARQAKNYAESDRI
RDQLKAEGITLIDQAGGVTRWLRE

Sequences:

>Translated_504_residues
MPLQIYNTLSRTKEPFTTLEAGKVQFYCCGVTVYDYCHLGHARSYIVWDIVRRYLQWRGYDVTYVQNYTDIDDKILKRAA
ETGQDWQAVTQTFIQAYEADMARLNILAADAYPKATESIPAIINLIRDLETRGVAYAAQGDVYFAVERFPGYGKLSGRLL
DQMEAGASGRVEQLEPAEQKKRHPLDFALWKATKPGEPSWDSPWGPGRPGWHIECSAMVNQCLGAEIDIHAGGSDLVFPH
HENEIAQSEAGLTPRLARYWMHNGFVNVGGEKMSKSLGNFTTIRQLLDTPLPILAGKTLHPMALRLFVLQAQYRKPIDFT
DDAIAAAQQSWQTLKEGLLFGYDYGAQLQWSDYTDPDFGNPANMRIPDPNVAVQRFQLAMDDDFNSPSGLVVLFELAKDL
RKAGNILSHQGETSTTSEQLREQWQTLVCLAQVLGLEAQPDSDAASTDSEDGLSEQAIEALIEERQAARQAKNYAESDRI
RDQLKAEGITLIDQAGGVTRWLRE
>Mature_503_residues
PLQIYNTLSRTKEPFTTLEAGKVQFYCCGVTVYDYCHLGHARSYIVWDIVRRYLQWRGYDVTYVQNYTDIDDKILKRAAE
TGQDWQAVTQTFIQAYEADMARLNILAADAYPKATESIPAIINLIRDLETRGVAYAAQGDVYFAVERFPGYGKLSGRLLD
QMEAGASGRVEQLEPAEQKKRHPLDFALWKATKPGEPSWDSPWGPGRPGWHIECSAMVNQCLGAEIDIHAGGSDLVFPHH
ENEIAQSEAGLTPRLARYWMHNGFVNVGGEKMSKSLGNFTTIRQLLDTPLPILAGKTLHPMALRLFVLQAQYRKPIDFTD
DAIAAAQQSWQTLKEGLLFGYDYGAQLQWSDYTDPDFGNPANMRIPDPNVAVQRFQLAMDDDFNSPSGLVVLFELAKDLR
KAGNILSHQGETSTTSEQLREQWQTLVCLAQVLGLEAQPDSDAASTDSEDGLSEQAIEALIEERQAARQAKNYAESDRIR
DQLKAEGITLIDQAGGVTRWLRE

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:
GO:0000166: Cysteinyl-tRNA synthetase
GO:0004812: Cysteinyl-tRNA synthetase
GO:0004817: Cysteinyl-tRNA synthetase
GO:0005524: Cysteinyl-tRNA synthetase
GO:0005737: Cysteinyl-tRNA synthetase
GO:0006418: Cysteinyl-tRNA synthetase
GO:0006423: Cysteinyl-tRNA synthetase

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=328, Percent_Identity=45.1219512195122, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI10835051, Length=251, Percent_Identity=41.4342629482072, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI21269877, Length=251, Percent_Identity=41.4342629482072, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI303304987, Length=251, Percent_Identity=41.4342629482072, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI62240992, Length=251, Percent_Identity=41.4342629482072, Blast_Score=194, Evalue=1e-49,
Organism=Escherichia coli, GI1786737, Length=504, Percent_Identity=43.0555555555556, Blast_Score=357, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17509795, Length=271, Percent_Identity=39.8523985239852, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17509797, Length=271, Percent_Identity=39.8523985239852, Blast_Score=193, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324082, Length=367, Percent_Identity=32.1525885558583, Blast_Score=183, Evalue=5e-47,
Organism=Drosophila melanogaster, GI19922218, Length=410, Percent_Identity=36.3414634146341, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI19922364, Length=373, Percent_Identity=33.2439678284182, Blast_Score=189, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 56474; Mature: 56343

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLQIYNTLSRTKEPFTTLEAGKVQFYCCGVTVYDYCHLGHARSYIVWDIVRRYLQWRGY
CCCHHHHHHHHCCCCCHHHCCCCEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
DVTYVQNYTDIDDKILKRAAETGQDWQAVTQTFIQAYEADMARLNILAADAYPKATESIP
CEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHH
AIINLIRDLETRGVAYAAQGDVYFAVERFPGYGKLSGRLLDQMEAGASGRVEQLEPAEQK
HHHHHHHHHHHCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHCCCHHHH
KRHPLDFALWKATKPGEPSWDSPWGPGRPGWHIECSAMVNQCLGAEIDIHAGGSDLVFPH
HCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCCCCC
HENEIAQSEAGLTPRLARYWMHNGFVNVGGEKMSKSLGNFTTIRQLLDTPLPILAGKTLH
CCCHHHHHHCCCCHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCH
PMALRLFVLQAQYRKPIDFTDDAIAAAQQSWQTLKEGLLFGYDYGAQLQWSDYTDPDFGN
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCCCCC
PANMRIPDPNVAVQRFQLAMDDDFNSPSGLVVLFELAKDLRKAGNILSHQGETSTTSEQL
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHCHHHHCCCCCCCHHHHH
REQWQTLVCLAQVLGLEAQPDSDAASTDSEDGLSEQAIEALIEERQAARQAKNYAESDRI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDQLKAEGITLIDQAGGVTRWLRE
HHHHHHCCEEEEECCCCHHHHHCC
>Mature Secondary Structure 
PLQIYNTLSRTKEPFTTLEAGKVQFYCCGVTVYDYCHLGHARSYIVWDIVRRYLQWRGY
CCHHHHHHHHCCCCCHHHCCCCEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
DVTYVQNYTDIDDKILKRAAETGQDWQAVTQTFIQAYEADMARLNILAADAYPKATESIP
CEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHH
AIINLIRDLETRGVAYAAQGDVYFAVERFPGYGKLSGRLLDQMEAGASGRVEQLEPAEQK
HHHHHHHHHHHCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHCCCHHHH
KRHPLDFALWKATKPGEPSWDSPWGPGRPGWHIECSAMVNQCLGAEIDIHAGGSDLVFPH
HCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCCCCC
HENEIAQSEAGLTPRLARYWMHNGFVNVGGEKMSKSLGNFTTIRQLLDTPLPILAGKTLH
CCCHHHHHHCCCCHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCH
PMALRLFVLQAQYRKPIDFTDDAIAAAQQSWQTLKEGLLFGYDYGAQLQWSDYTDPDFGN
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCCCCC
PANMRIPDPNVAVQRFQLAMDDDFNSPSGLVVLFELAKDLRKAGNILSHQGETSTTSEQL
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHCHHHHCCCCCCCHHHHH
REQWQTLVCLAQVLGLEAQPDSDAASTDSEDGLSEQAIEALIEERQAARQAKNYAESDRI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDQLKAEGITLIDQAGGVTRWLRE
HHHHHHCCEEEEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA