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The map label for this gene is accD

Identifier: 158337009

GI number: 158337009

Start: 3935128

End: 3936042

Strand: Direct

Name: accD

Synonym: AM1_3882

Alternate gene names: 158337009

Gene position: 3935128-3936042 (Clockwise)

Preceding gene: 158337003

Following gene: 158337010

Centisome position: 60.51

GC content: 51.8

Gene sequence:

>915_bases
ATGTCTTTATTTGATTGGTTTGCAAATCGACGAAAATCTCATCCTGTGACCAAAGCACAGCCAGAACGAGAAATCTCTGA
TGGCTTGTGGTCGAAGTGTGAGTCGTGTGGTGCTCTAACCTACACCAAAGATTTACGGGCCAATCAAATGGTGTGCCTAG
AATGTGGCCACCATTTGCGCGTCACCAGTGATGAGCGGATTGCGCAGCTGATTGATGCAGAGACCTGGGTGGCGATGGAC
AATAACTTAGTTGCCTGTGACCCTCTCCAGTTTCGAGATCGCAAAGCCTATTGCGATCGCATTCAGGAATACCAAAGCAA
AACTGGTCTCCAGGACGCTGTCCAAACAGGGGTGGGTGAACTTGATGGTCTGCCTCTCGCCTTGGGTGTCATGGACTTCC
GGTTTATGGGAGGCAGTATGGGGTCCGTCGTTGGCGAGAAACTGACCCGTTTGATCGAGCATGCCACGCAAAACCGTCTT
CCTTTAGTGATCGTTTGTGCGTCCGGTGGTGCTCGCATGCAAGAAGGGATGCTGAGCCTAATGCAAATGGCGAAAACCTC
TGCCGCGCTAGATCAGCACAGAACCAACCGTTTACTCTATATCCCCGTCCTCACCCACCCCACCACTGGTGGGGTGACCG
CGAGCTTTGCGATGCTGGGGGATATGATTTTGGCTGAACCCAAAGCAACTATCGGCTTTGCCGGTCGCCGGGTAGTCGAA
CAAACCCTGCGAGAAAAACTACCGGATGATTTCCAAACGGCAGAATATTTACTCAGTCATGGATTTGTGGATGCCATTGT
CCCGAGACCAGAGTTAAAGCGAACCTTAGCCCAGCTGATTCGCATTCATGCTCAAATGCCGATGGCCTCAGATGTTTCAC
CTGCCGCTGTTCCAGTTGCCGCTGCCGTTGAATAG

Upstream 100 bases:

>100_bases
TTGGGCATCTCAAATGGGTGAGGATAACGGTAAACTTATGCCTCAATTGCTGCGGTCTTGCAGGTGCTGAATTCATTTTT
GAGAGGAATCAAGCGTTTCC

Downstream 100 bases:

>100_bases
GGGATAGGGGGCTGAACCTTGATCCTCTTCCATTCCAGATTTGACCAATTTATGGAATCTGGATTTGGGAAAGGGACGCC
TCAATGGCATGATATTAGAT

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSLFDWFANRRKSHPVTKAQPEREISDGLWSKCESCGALTYTKDLRANQMVCLECGHHLRVTSDERIAQLIDAETWVAMD
NNLVACDPLQFRDRKAYCDRIQEYQSKTGLQDAVQTGVGELDGLPLALGVMDFRFMGGSMGSVVGEKLTRLIEHATQNRL
PLVIVCASGGARMQEGMLSLMQMAKTSAALDQHRTNRLLYIPVLTHPTTGGVTASFAMLGDMILAEPKATIGFAGRRVVE
QTLREKLPDDFQTAEYLLSHGFVDAIVPRPELKRTLAQLIRIHAQMPMASDVSPAAVPVAAAVE

Sequences:

>Translated_304_residues
MSLFDWFANRRKSHPVTKAQPEREISDGLWSKCESCGALTYTKDLRANQMVCLECGHHLRVTSDERIAQLIDAETWVAMD
NNLVACDPLQFRDRKAYCDRIQEYQSKTGLQDAVQTGVGELDGLPLALGVMDFRFMGGSMGSVVGEKLTRLIEHATQNRL
PLVIVCASGGARMQEGMLSLMQMAKTSAALDQHRTNRLLYIPVLTHPTTGGVTASFAMLGDMILAEPKATIGFAGRRVVE
QTLREKLPDDFQTAEYLLSHGFVDAIVPRPELKRTLAQLIRIHAQMPMASDVSPAAVPVAAAVE
>Mature_303_residues
SLFDWFANRRKSHPVTKAQPEREISDGLWSKCESCGALTYTKDLRANQMVCLECGHHLRVTSDERIAQLIDAETWVAMDN
NLVACDPLQFRDRKAYCDRIQEYQSKTGLQDAVQTGVGELDGLPLALGVMDFRFMGGSMGSVVGEKLTRLIEHATQNRLP
LVIVCASGGARMQEGMLSLMQMAKTSAALDQHRTNRLLYIPVLTHPTTGGVTASFAMLGDMILAEPKATIGFAGRRVVEQ
TLREKLPDDFQTAEYLLSHGFVDAIVPRPELKRTLAQLIRIHAQMPMASDVSPAAVPVAAAVE

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:
GO:0000166: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0003989: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0005524: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0005737: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0006633: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0008610: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0009317: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0016874: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0046872: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=293, Percent_Identity=47.7815699658703, Blast_Score=272, Evalue=2e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_ACAM1 (B0C728)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001518184.1
- ProteinModelPortal:   B0C728
- SMR:   B0C728
- GeneID:   5682686
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_3882
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   PRK05654
- BioCyc:   AMAR329726:AM1_3882-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 33484; Mature: 33353

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFDWFANRRKSHPVTKAQPEREISDGLWSKCESCGALTYTKDLRANQMVCLECGHHLR
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHCCCCCEEEEECCCCEE
VTSDERIAQLIDAETWVAMDNNLVACDPLQFRDRKAYCDRIQEYQSKTGLQDAVQTGVGE
ECCHHHHHHHHCCHHEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
LDGLPLALGVMDFRFMGGSMGSVVGEKLTRLIEHATQNRLPLVIVCASGGARMQEGMLSL
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
MQMAKTSAALDQHRTNRLLYIPVLTHPTTGGVTASFAMLGDMILAEPKATIGFAGRRVVE
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QTLREKLPDDFQTAEYLLSHGFVDAIVPRPELKRTLAQLIRIHAQMPMASDVSPAAVPVA
HHHHHHCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
AAVE
HCCC
>Mature Secondary Structure 
SLFDWFANRRKSHPVTKAQPEREISDGLWSKCESCGALTYTKDLRANQMVCLECGHHLR
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHCCCCCEEEEECCCCEE
VTSDERIAQLIDAETWVAMDNNLVACDPLQFRDRKAYCDRIQEYQSKTGLQDAVQTGVGE
ECCHHHHHHHHCCHHEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
LDGLPLALGVMDFRFMGGSMGSVVGEKLTRLIEHATQNRLPLVIVCASGGARMQEGMLSL
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
MQMAKTSAALDQHRTNRLLYIPVLTHPTTGGVTASFAMLGDMILAEPKATIGFAGRRVVE
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QTLREKLPDDFQTAEYLLSHGFVDAIVPRPELKRTLAQLIRIHAQMPMASDVSPAAVPVA
HHHHHHCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
AAVE
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA