Click here to switch to the map view.

The map label for this gene is ilvE [H]

Identifier: 158336939

GI number: 158336939

Start: 3863305

End: 3864186

Strand: Direct

Name: ilvE [H]

Synonym: AM1_3810

Alternate gene names: 158336939

Gene position: 3863305-3864186 (Clockwise)

Preceding gene: 158336938

Following gene: 158336944

Centisome position: 59.4

GC content: 48.87

Gene sequence:

>882_bases
ATGAGTCTACTGACAAATCTCAATGGTGTGATAGCTGCATCGGCAACGGTTTCCGTTTTAGATCGCGGTTTCTTGTATGG
TGACAGCATTTACGAAGTGGTGCGAACGTTTCAGGGTCGCCACTTTGGACTGCAAGAGCATCTGGATCGCCTCCGTCAGT
CTGCAGAGCATCTATATATGGAGGTGCCGTGGAGCGATCAGCATATTCAAGCTGAAGTAGAACGTACGCTCCAACAAGCG
CCGTGGCAGGAGTCCTATATCCGCATTGTGGTCAGCCGGGGGACTGAAACTAAAATTAGTCTTCAACCCAGTCCGAACCT
GCAACCCAGCTTACTCATTGTCGCTTCGGAAATCTCGCCAGAGCCCATCTTGTCAGAGCAAGGGATACATCTGGTGATTA
GTGAGCGGCTCCGTAATGATCGTCAAGCTCTGTCTCCAGCCGCTAAAACAGGGAATTATCTCAACAATATTTTGGCGTTA
CTAGAAGCCCAGCAGCAGGGTGCTGAAGATGCGCTGATGCTCAATCAGCAGGGCGACATTACTGAAGCTACAACCAGTAA
TCTCTGGATTGTCCGAGAAGGTGTGGTGCAAACCCCACCCGCAGATGTGGGGATTTTGAAGGGCATTACCCGTTATTTCC
TGTGGCGAATTCTGCAAACCCATGGCATTCCCTGTGAGGAAGTTATCCTCAAGCCAGAAGACTTATGGTCAGCGGAAGAA
GCATTTTTAAGCTCTTCTGTGCGGCTAATGATGCCTGTGAACCAAATCAATGAGTATCGACTTCCCCAGTGTCCTGGGAA
AATAACGCGATTTTTATGGGAGGAGTTTTTGAGGTTGATGGCGAAGGAAAGCCACAGCTTTGAGAAAATACTGCCAGTTT
AA

Upstream 100 bases:

>100_bases
ACGGGTAAATAAATATGAATTGATCTCAGGATTCTTTACCCAGGTTAGGGATAGGGGTCTGTTCGGGTAGATTGTCTGTA
GTACTTTGGATTGGCGGGCC

Downstream 100 bases:

>100_bases
TTATTTTGGATGGTATCCAACCAATGTGAATCACGCTTAAAACGTAGGTACTAAAGCCAAGTCATTTTCTTGGTATCAAA
GAGCTGACAGTCAGTAACAA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSLLTNLNGVIAASATVSVLDRGFLYGDSIYEVVRTFQGRHFGLQEHLDRLRQSAEHLYMEVPWSDQHIQAEVERTLQQA
PWQESYIRIVVSRGTETKISLQPSPNLQPSLLIVASEISPEPILSEQGIHLVISERLRNDRQALSPAAKTGNYLNNILAL
LEAQQQGAEDALMLNQQGDITEATTSNLWIVREGVVQTPPADVGILKGITRYFLWRILQTHGIPCEEVILKPEDLWSAEE
AFLSSSVRLMMPVNQINEYRLPQCPGKITRFLWEEFLRLMAKESHSFEKILPV

Sequences:

>Translated_293_residues
MSLLTNLNGVIAASATVSVLDRGFLYGDSIYEVVRTFQGRHFGLQEHLDRLRQSAEHLYMEVPWSDQHIQAEVERTLQQA
PWQESYIRIVVSRGTETKISLQPSPNLQPSLLIVASEISPEPILSEQGIHLVISERLRNDRQALSPAAKTGNYLNNILAL
LEAQQQGAEDALMLNQQGDITEATTSNLWIVREGVVQTPPADVGILKGITRYFLWRILQTHGIPCEEVILKPEDLWSAEE
AFLSSSVRLMMPVNQINEYRLPQCPGKITRFLWEEFLRLMAKESHSFEKILPV
>Mature_292_residues
SLLTNLNGVIAASATVSVLDRGFLYGDSIYEVVRTFQGRHFGLQEHLDRLRQSAEHLYMEVPWSDQHIQAEVERTLQQAP
WQESYIRIVVSRGTETKISLQPSPNLQPSLLIVASEISPEPILSEQGIHLVISERLRNDRQALSPAAKTGNYLNNILALL
EAQQQGAEDALMLNQQGDITEATTSNLWIVREGVVQTPPADVGILKGITRYFLWRILQTHGIPCEEVILKPEDLWSAEEA
FLSSSVRLMMPVNQINEYRLPQCPGKITRFLWEEFLRLMAKESHSFEKILPV

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=281, Percent_Identity=27.4021352313167, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787338, Length=245, Percent_Identity=26.9387755102041, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 33194; Mature: 33063

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLTNLNGVIAASATVSVLDRGFLYGDSIYEVVRTFQGRHFGLQEHLDRLRQSAEHLYM
CCCHHCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEE
EVPWSDQHIQAEVERTLQQAPWQESYIRIVVSRGTETKISLQPSPNLQPSLLIVASEISP
ECCCCCHHHHHHHHHHHHHCCCHHHEEEEEEECCCCEEEEECCCCCCCCEEEEEEECCCC
EPILSEQGIHLVISERLRNDRQALSPAAKTGNYLNNILALLEAQQQGAEDALMLNQQGDI
CCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCC
TEATTSNLWIVREGVVQTPPADVGILKGITRYFLWRILQTHGIPCEEVILKPEDLWSAEE
CCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCHHHH
AFLSSSVRLMMPVNQINEYRLPQCPGKITRFLWEEFLRLMAKESHSFEKILPV
HHHHCCCEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure 
SLLTNLNGVIAASATVSVLDRGFLYGDSIYEVVRTFQGRHFGLQEHLDRLRQSAEHLYM
CCHHCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEE
EVPWSDQHIQAEVERTLQQAPWQESYIRIVVSRGTETKISLQPSPNLQPSLLIVASEISP
ECCCCCHHHHHHHHHHHHHCCCHHHEEEEEEECCCCEEEEECCCCCCCCEEEEEEECCCC
EPILSEQGIHLVISERLRNDRQALSPAAKTGNYLNNILALLEAQQQGAEDALMLNQQGDI
CCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCC
TEATTSNLWIVREGVVQTPPADVGILKGITRYFLWRILQTHGIPCEEVILKPEDLWSAEE
CCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCHHHH
AFLSSSVRLMMPVNQINEYRLPQCPGKITRFLWEEFLRLMAKESHSFEKILPV
HHHHCCCEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]