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The map label for this gene is lss [H]

Identifier: 158336937

GI number: 158336937

Start: 3862054

End: 3862737

Strand: Direct

Name: lss [H]

Synonym: AM1_3808

Alternate gene names: 158336937

Gene position: 3862054-3862737 (Clockwise)

Preceding gene: 158336936

Following gene: 158336938

Centisome position: 59.38

GC content: 49.71

Gene sequence:

>684_bases
GTGAGTGCGTTCGTCTCTGATCTGCCCCGTCTCGTCTATAGTCAACCGATTCCTTACCACCGATCGACTTCGACGATTAT
CACACCTGATTCTGTTAGTGCAGGAGCGTCCCCTAAGGCAGTGGGTGGGGCACGGTCACCGCAGCCGTTGAGTCGTAATC
GATATCAGGTACCCTTGCAAGCCTATGCAACCGTAACGTCTCCCCTACGGGGATTTTGCCATCCCTTAAAGGGACAAGGC
CATCTGAGCCAGGGTATAAGGGGCCAAACCCATCGAGGCCGAATGGAATATGCCTACGATTTAGCAGTAAATATCGGCAC
TCCAGTTTATGCCATGCGTTCAGGTAAAGTGATCGCCATCCGAGATTACTATCCTGATAATGGCGGTAGCCAATCCAAAT
CTTCTCGTTTTAACTATGTATGGCTAGAGCATGATGGTGGCTATCGCTCCGCCTATATCCATCTGCAAAAGAAATTTAAT
CGAAAAGTCAACCTAAAAGTTGGACAGTGGGTGCATGCCCAACAGTTAATTGGCTTTAGCGGTAATTCGGGTTGGAGTTC
TGGTCCTCACTTACATGTCGAGGTCCAAAGACCTGAACGCGTGAAACAGCTTGCGAAGAAATTTTCCAAGACGGTCCCGT
TCGAGATAGCTGGGTATTGTCCTGCAGCCCGAGTGGCTCACTAA

Upstream 100 bases:

>100_bases
TGAAATCTTAATTCAACGAGGATTAATCAGTCACCAGCAGCTGCAACAGGTGCTCAATGAACAGCGGTGGCGTAATGTCG
TGACGGCTGTATTGCTTTCC

Downstream 100 bases:

>100_bases
TCTCAACCAGGGATAAAATAGCCTACCCCCAAGGAGAAGATTACGGTTTCCCCTAATGCTCTTCCCTAGGTGCATTGAGG
AGAAAGCGGTAACATTAGTA

Product: peptidase M23 domain-containing protein

Products: NA

Alternate protein names: Glycyl-glycine endopeptidase [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSAFVSDLPRLVYSQPIPYHRSTSTIITPDSVSAGASPKAVGGARSPQPLSRNRYQVPLQAYATVTSPLRGFCHPLKGQG
HLSQGIRGQTHRGRMEYAYDLAVNIGTPVYAMRSGKVIAIRDYYPDNGGSQSKSSRFNYVWLEHDGGYRSAYIHLQKKFN
RKVNLKVGQWVHAQQLIGFSGNSGWSSGPHLHVEVQRPERVKQLAKKFSKTVPFEIAGYCPAARVAH

Sequences:

>Translated_227_residues
MSAFVSDLPRLVYSQPIPYHRSTSTIITPDSVSAGASPKAVGGARSPQPLSRNRYQVPLQAYATVTSPLRGFCHPLKGQG
HLSQGIRGQTHRGRMEYAYDLAVNIGTPVYAMRSGKVIAIRDYYPDNGGSQSKSSRFNYVWLEHDGGYRSAYIHLQKKFN
RKVNLKVGQWVHAQQLIGFSGNSGWSSGPHLHVEVQRPERVKQLAKKFSKTVPFEIAGYCPAARVAH
>Mature_226_residues
SAFVSDLPRLVYSQPIPYHRSTSTIITPDSVSAGASPKAVGGARSPQPLSRNRYQVPLQAYATVTSPLRGFCHPLKGQGH
LSQGIRGQTHRGRMEYAYDLAVNIGTPVYAMRSGKVIAIRDYYPDNGGSQSKSSRFNYVWLEHDGGYRSAYIHLQKKFNR
KVNLKVGQWVHAQQLIGFSGNSGWSSGPHLHVEVQRPERVKQLAKKFSKTVPFEIAGYCPAARVAH

Specific function: Lyses staphylococcal cells by hydrolyzing the polyglycine interpeptide bridges of the peptidoglycan [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047
- InterPro:   IPR002886
- InterPro:   IPR003646
- InterPro:   IPR013667 [H]

Pfam domain/function: PF01551 Peptidase_M23; PF08460 SH3_5 [H]

EC number: =3.4.24.75 [H]

Molecular weight: Translated: 25165; Mature: 25034

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFVSDLPRLVYSQPIPYHRSTSTIITPDSVSAGASPKAVGGARSPQPLSRNRYQVPLQ
CCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHH
AYATVTSPLRGFCHPLKGQGHLSQGIRGQTHRGRMEYAYDLAVNIGTPVYAMRSGKVIAI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEECCCCEEEE
RDYYPDNGGSQSKSSRFNYVWLEHDGGYRSAYIHLQKKFNRKVNLKVGQWVHAQQLIGFS
EECCCCCCCCCCCCCCEEEEEEEECCCEEEEEEEEEHHCCCEEEEEECCEEEHHHHEECC
GNSGWSSGPHLHVEVQRPERVKQLAKKFSKTVPFEIAGYCPAARVAH
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCHHCCC
>Mature Secondary Structure 
SAFVSDLPRLVYSQPIPYHRSTSTIITPDSVSAGASPKAVGGARSPQPLSRNRYQVPLQ
CCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHH
AYATVTSPLRGFCHPLKGQGHLSQGIRGQTHRGRMEYAYDLAVNIGTPVYAMRSGKVIAI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEECCCCEEEE
RDYYPDNGGSQSKSSRFNYVWLEHDGGYRSAYIHLQKKFNRKVNLKVGQWVHAQQLIGFS
EECCCCCCCCCCCCCCEEEEEEEECCCEEEEEEEEEHHCCCEEEEEECCEEEHHHHEECC
GNSGWSSGPHLHVEVQRPERVKQLAKKFSKTVPFEIAGYCPAARVAH
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3547405; 9106216 [H]