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The map label for this gene is desA [H]

Identifier: 158336891

GI number: 158336891

Start: 3818633

End: 3819694

Strand: Reverse

Name: desA [H]

Synonym: AM1_3759

Alternate gene names: 158336891

Gene position: 3819694-3818633 (Counterclockwise)

Preceding gene: 158336896

Following gene: 158336889

Centisome position: 58.73

GC content: 46.05

Gene sequence:

>1062_bases
GTGCAAAACTCTACCGGTATTGAAACCAGAGGCCCTGACGTCTCTAGGTCTAGAGAATTACCTTTTACCCTTCAAGATAT
AAGGGCAGCCATTCCCCCTCATTGCTTTGAGCCCTCAGCCTGGCGATCTCTCTCATATTTCTTTTTAGATATCGGTATTA
TCGCTGGTTTATACGCCATTGCCTATCAAATTGATGCTCTATGGTTTTGGCCCATCTTTTGGTTAGCTCAAGGCACCATG
TTTTGGGCTTTATTCGTCGTCGGCCATGACTGTGGTCATCGCTCCTTTTCCAAATACAAGTGGTTAAACGATCTGATCGG
ACATCTCAGCCATACGCCAATTTTGGTTCCTTTCCATGGTTGGCGCATTAGTCACCGGACCCACCATGCCAATACAGGCA
ATATCGACACGGACGAAAGTTGGTACCCTCCCACGGAAACGCAATACCGAGAGATGCCGAAGGATGTCAAATTTGTCCGT
TACTATTTGACCCTATTGGCCTATCCCATTTACCTCTTCAAACGGTCTCCTGGACGCAAGGGCTCTCATTTCCTACCCAG
TAGCCCTTTATTCAAGCCTTCCGAGAAATGGGACGTCATCACCAGTACAGTCCTATGGGGAGCCATGATCGCTTTTCTAG
CAGCGCTCACCTATACCAATGGCTGGTTATTCTTAGTTAAATATTATCTCGGCCCCTATATTGTCTTTATCGTTTGGTTA
GATGTTGTCACGCTGTTGCACCATACCGTACCCAGCATACCTTGGTACCCCAATGATAACTGGTATTTTCTCAAAGGTGC
CCTCTCCACCATCGACCATGACTATGGGTTTATCAATCCTATCCATCACAATATTGGTACTCATGTCGCCCACCATATTT
TCTTGGGTATGCCTCACTATCATTTACTGACTGCAACAGAAGCAATCAAGCCGGTCTTAGGTGAGTACTATCGGAAGTCT
TCCGATCCCATTTGGAAAAGTTTATGGACTGCCTTAAGAGATTGCCGATACGTTCCTGATCATGGGGAAAAAGTTTACTA
TCAAGCTGACGCCAAGCGCTAA

Upstream 100 bases:

>100_bases
TTGTAAACTTTTACCGGAGTCATTGCTTGACTTTGATTACGACTTGTTAAGAGATAGAATGAGACTCGGTCACTACAGCG
TAAGGAAGCAGTATTTTTTC

Downstream 100 bases:

>100_bases
ATTTCTCTTTTATGCTTTTTCTCTAGGCTAAATTCGTTCAGGAAAGAGAGTGAAGCGATAAGCCTCAAATCAATTTCATC
GGCCAATATTGAGCTTCGAC

Product: omega-3 fatty acid desaturase

Products: NA

Alternate protein names: Delta(12) desaturase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MQNSTGIETRGPDVSRSRELPFTLQDIRAAIPPHCFEPSAWRSLSYFFLDIGIIAGLYAIAYQIDALWFWPIFWLAQGTM
FWALFVVGHDCGHRSFSKYKWLNDLIGHLSHTPILVPFHGWRISHRTHHANTGNIDTDESWYPPTETQYREMPKDVKFVR
YYLTLLAYPIYLFKRSPGRKGSHFLPSSPLFKPSEKWDVITSTVLWGAMIAFLAALTYTNGWLFLVKYYLGPYIVFIVWL
DVVTLLHHTVPSIPWYPNDNWYFLKGALSTIDHDYGFINPIHHNIGTHVAHHIFLGMPHYHLLTATEAIKPVLGEYYRKS
SDPIWKSLWTALRDCRYVPDHGEKVYYQADAKR

Sequences:

>Translated_353_residues
MQNSTGIETRGPDVSRSRELPFTLQDIRAAIPPHCFEPSAWRSLSYFFLDIGIIAGLYAIAYQIDALWFWPIFWLAQGTM
FWALFVVGHDCGHRSFSKYKWLNDLIGHLSHTPILVPFHGWRISHRTHHANTGNIDTDESWYPPTETQYREMPKDVKFVR
YYLTLLAYPIYLFKRSPGRKGSHFLPSSPLFKPSEKWDVITSTVLWGAMIAFLAALTYTNGWLFLVKYYLGPYIVFIVWL
DVVTLLHHTVPSIPWYPNDNWYFLKGALSTIDHDYGFINPIHHNIGTHVAHHIFLGMPHYHLLTATEAIKPVLGEYYRKS
SDPIWKSLWTALRDCRYVPDHGEKVYYQADAKR
>Mature_353_residues
MQNSTGIETRGPDVSRSRELPFTLQDIRAAIPPHCFEPSAWRSLSYFFLDIGIIAGLYAIAYQIDALWFWPIFWLAQGTM
FWALFVVGHDCGHRSFSKYKWLNDLIGHLSHTPILVPFHGWRISHRTHHANTGNIDTDESWYPPTETQYREMPKDVKFVR
YYLTLLAYPIYLFKRSPGRKGSHFLPSSPLFKPSEKWDVITSTVLWGAMIAFLAALTYTNGWLFLVKYYLGPYIVFIVWL
DVVTLLHHTVPSIPWYPNDNWYFLKGALSTIDHDYGFINPIHHNIGTHVAHHIFLGMPHYHLLTATEAIKPVLGEYYRKS
SDPIWKSLWTALRDCRYVPDHGEKVYYQADAKR

Specific function: Can introduce a second cis double bond at the Delta(12) position of fatty acid bound to membranes glycerolipids. This enzyme is involved in chilling tolerance because the phase transition temperature of lipids of cellular membranes depends on the degree o

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17542730, Length=329, Percent_Identity=38.9057750759878, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71999459, Length=322, Percent_Identity=36.0248447204969, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804
- InterPro:   IPR005803 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 41137; Mature: 41137

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNSTGIETRGPDVSRSRELPFTLQDIRAAIPPHCFEPSAWRSLSYFFLDIGIIAGLYAI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AYQIDALWFWPIFWLAQGTMFWALFVVGHDCGHRSFSKYKWLNDLIGHLSHTPILVPFHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECC
WRISHRTHHANTGNIDTDESWYPPTETQYREMPKDVKFVRYYLTLLAYPIYLFKRSPGRK
EEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
GSHFLPSSPLFKPSEKWDVITSTVLWGAMIAFLAALTYTNGWLFLVKYYLGPYIVFIVWL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DVVTLLHHTVPSIPWYPNDNWYFLKGALSTIDHDYGFINPIHHNIGTHVAHHIFLGMPHY
HHHHHHHHHCCCCCCCCCCCEEEEECHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCH
HLLTATEAIKPVLGEYYRKSSDPIWKSLWTALRDCRYVPDHGEKVYYQADAKR
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MQNSTGIETRGPDVSRSRELPFTLQDIRAAIPPHCFEPSAWRSLSYFFLDIGIIAGLYAI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AYQIDALWFWPIFWLAQGTMFWALFVVGHDCGHRSFSKYKWLNDLIGHLSHTPILVPFHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECC
WRISHRTHHANTGNIDTDESWYPPTETQYREMPKDVKFVRYYLTLLAYPIYLFKRSPGRK
EEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
GSHFLPSSPLFKPSEKWDVITSTVLWGAMIAFLAALTYTNGWLFLVKYYLGPYIVFIVWL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DVVTLLHHTVPSIPWYPNDNWYFLKGALSTIDHDYGFINPIHHNIGTHVAHHIFLGMPHY
HHHHHHHHHCCCCCCCCCCCEEEEECHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCH
HLLTATEAIKPVLGEYYRKSSDPIWKSLWTALRDCRYVPDHGEKVYYQADAKR
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2118597; 8905231 [H]