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The map label for this gene is cobL [H]

Identifier: 158336797

GI number: 158336797

Start: 3721184

End: 3722440

Strand: Direct

Name: cobL [H]

Synonym: AM1_3665

Alternate gene names: 158336797

Gene position: 3721184-3722440 (Clockwise)

Preceding gene: 158336796

Following gene: 158336799

Centisome position: 57.22

GC content: 44.55

Gene sequence:

>1257_bases
ATGACGCCCATTCATGTTATTGGGATCGGGCTGACCGGTGGATCAGGGTTGCAGTCCCACCTCCATATGCTGATTGATCA
AGCCACTGTCTTAGTCGGCAGCGAACGACATCTCCAATACTTTCCATCGCATCCAGGAAAACGCATTACCCTGACGAATT
TTGCTCAAGGTTTAGAGGCGATTCAACAGCATTTAGATCAGTCTCCCAACCCACTCGTGGTCGTGATAACGTCTGGAGAT
CCGCTATTTTTCGGGTTTGGCCGTCTATTGTTGCAAACTTTTGCGGCTGATCTATTGTGCTTTCATCCCTATCTCAGTTC
TGTCCAAATTGCTTTTAACCGCCTCAAGGTGCCTTGGCAAGATGCTGAGGTGATTAGTGTTCATGGTCGTTCCCTATCTT
CCTTGGTTACAGCATGGCAAAAGGGAGTGAGAAAAATTGCAGTGTTGACGGATCATAAGAATACGCCTGCTGCGATCGCA
AAATTATTCCTCAGTTTAAATCTACCCATCCACTATGAATTTTGGGTGTGTGAAAATCTAGAAGGCTCAGATGAGCGTGT
TCAAAAATTTGAACCCAAGACGCTACTCAACCAACAATTCTCAGCTCTAAATGTTGTCGTTTTACTACGTTATGACCTAG
AAAAGCGAGAAAAATCTGATCTTGCCTCTTTACCAGTTCTTGGACTTCCTGATCAGGCTTTTTATAGCTTTGCCGATCGT
CCTGGGTTAATGACCAAGCGAGAAATTCGTATTCTGGCATTGGCTGAATTACAGCTGCAAGACCATCAAATAATTTGGGA
TATTGGATCGGGTACTGGCTCAGTTGCGATTGAAACCGCTCGCATAGTCCCTAGTTCCCAAGTTTATGCCGTTGAAAAAA
CAGCTTTAGGGACCCAGCTCATCCACCAAAATTGTCAGCATTTTCAGGTGAACAATGTTCATATCGTTTTGGGCGAAGCC
CCCACCGCATTAAATAATTTGCCTGACCCCCACCGAATATTTATTGGAGGAAGTGGAGGGCATCTTCAGGAGATCTTAAA
TTATTGCCAAATGCGACTTGACCTATCAGGTGTCATCGTCGTGAGCCTGGCAACCTTAGAAAATTTTTATATTGCTACCC
AGTGGTTTGATAAACCCAATTGGGTAGTAGAACATCTGCAAATTCAACTATCACGTTCTGTTCCCGTTGCATCCATGACT
CGATTAACTCCATTAAACCCAGTCATGCTGATCAGAGCCAGCAGAAACCCTAACTAG

Upstream 100 bases:

>100_bases
CCCATATTCGAACGGAGGGGCGCAAAGGGGGATCGCCTGTGGCGGCGGCAATTACGAATGCACTATTGACGCTGGCTTGG
CAACAAAGGAATACACACTG

Downstream 100 bases:

>100_bases
AATTTAGATAGAGCTTCTGTTAAATAATGCATTTATGAGAAATACATTAGACTCTGAAGTCGTTTGATGTTTATGCCGAA
TTTCAGCTAATAAGGAAACA

Product: precorrin-6y C5,15-methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MTPIHVIGIGLTGGSGLQSHLHMLIDQATVLVGSERHLQYFPSHPGKRITLTNFAQGLEAIQQHLDQSPNPLVVVITSGD
PLFFGFGRLLLQTFAADLLCFHPYLSSVQIAFNRLKVPWQDAEVISVHGRSLSSLVTAWQKGVRKIAVLTDHKNTPAAIA
KLFLSLNLPIHYEFWVCENLEGSDERVQKFEPKTLLNQQFSALNVVVLLRYDLEKREKSDLASLPVLGLPDQAFYSFADR
PGLMTKREIRILALAELQLQDHQIIWDIGSGTGSVAIETARIVPSSQVYAVEKTALGTQLIHQNCQHFQVNNVHIVLGEA
PTALNNLPDPHRIFIGGSGGHLQEILNYCQMRLDLSGVIVVSLATLENFYIATQWFDKPNWVVEHLQIQLSRSVPVASMT
RLTPLNPVMLIRASRNPN

Sequences:

>Translated_418_residues
MTPIHVIGIGLTGGSGLQSHLHMLIDQATVLVGSERHLQYFPSHPGKRITLTNFAQGLEAIQQHLDQSPNPLVVVITSGD
PLFFGFGRLLLQTFAADLLCFHPYLSSVQIAFNRLKVPWQDAEVISVHGRSLSSLVTAWQKGVRKIAVLTDHKNTPAAIA
KLFLSLNLPIHYEFWVCENLEGSDERVQKFEPKTLLNQQFSALNVVVLLRYDLEKREKSDLASLPVLGLPDQAFYSFADR
PGLMTKREIRILALAELQLQDHQIIWDIGSGTGSVAIETARIVPSSQVYAVEKTALGTQLIHQNCQHFQVNNVHIVLGEA
PTALNNLPDPHRIFIGGSGGHLQEILNYCQMRLDLSGVIVVSLATLENFYIATQWFDKPNWVVEHLQIQLSRSVPVASMT
RLTPLNPVMLIRASRNPN
>Mature_417_residues
TPIHVIGIGLTGGSGLQSHLHMLIDQATVLVGSERHLQYFPSHPGKRITLTNFAQGLEAIQQHLDQSPNPLVVVITSGDP
LFFGFGRLLLQTFAADLLCFHPYLSSVQIAFNRLKVPWQDAEVISVHGRSLSSLVTAWQKGVRKIAVLTDHKNTPAAIAK
LFLSLNLPIHYEFWVCENLEGSDERVQKFEPKTLLNQQFSALNVVVLLRYDLEKREKSDLASLPVLGLPDQAFYSFADRP
GLMTKREIRILALAELQLQDHQIIWDIGSGTGSVAIETARIVPSSQVYAVEKTALGTQLIHQNCQHFQVNNVHIVLGEAP
TALNNLPDPHRIFIGGSGGHLQEILNYCQMRLDLSGVIVVSLATLENFYIATQWFDKPNWVVEHLQIQLSRSVPVASMTR
LTPLNPVMLIRASRNPN

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 46521; Mature: 46390

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPIHVIGIGLTGGSGLQSHLHMLIDQATVLVGSERHLQYFPSHPGKRITLTNFAQGLEA
CCCEEEEEEEECCCCCHHHHHHHHHHHHHEEECCCCCEEECCCCCCCEEEHHHHHHHHHH
IQQHLDQSPNPLVVVITSGDPLFFGFGRLLLQTFAADLLCFHPYLSSVQIAFNRLKVPWQ
HHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DAEVISVHGRSLSSLVTAWQKGVRKIAVLTDHKNTPAAIAKLFLSLNLPIHYEFWVCENL
CCEEEEECCCCHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEECCC
EGSDERVQKFEPKTLLNQQFSALNVVVLLRYDLEKREKSDLASLPVLGLPDQAFYSFADR
CCCHHHHHHCCCHHHHHHHHHHEEEEEEEEECHHHHHHCHHHCCCCCCCCCHHHHHHCCC
PGLMTKREIRILALAELQLQDHQIIWDIGSGTGSVAIETARIVPSSQVYAVEKTALGTQL
CCCCCCCCEEEEEEEEEEECCCEEEEEECCCCCCEEEEEEEECCCCCEEEEEHHHHHHHH
IHQNCQHFQVNNVHIVLGEAPTALNNLPDPHRIFIGGSGGHLQEILNYCQMRLDLSGVIV
HHCCCCEEEECCEEEEECCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEE
VSLATLENFYIATQWFDKPNWVVEHLQIQLSRSVPVASMTRLTPLNPVMLIRASRNPN
EEEEHHCCEEEEEEECCCCCHHEEEHEEEECCCCCHHHHHCCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
TPIHVIGIGLTGGSGLQSHLHMLIDQATVLVGSERHLQYFPSHPGKRITLTNFAQGLEA
CCEEEEEEEECCCCCHHHHHHHHHHHHHEEECCCCCEEECCCCCCCEEEHHHHHHHHHH
IQQHLDQSPNPLVVVITSGDPLFFGFGRLLLQTFAADLLCFHPYLSSVQIAFNRLKVPWQ
HHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DAEVISVHGRSLSSLVTAWQKGVRKIAVLTDHKNTPAAIAKLFLSLNLPIHYEFWVCENL
CCEEEEECCCCHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEECCC
EGSDERVQKFEPKTLLNQQFSALNVVVLLRYDLEKREKSDLASLPVLGLPDQAFYSFADR
CCCHHHHHHCCCHHHHHHHHHHEEEEEEEEECHHHHHHCHHHCCCCCCCCCHHHHHHCCC
PGLMTKREIRILALAELQLQDHQIIWDIGSGTGSVAIETARIVPSSQVYAVEKTALGTQL
CCCCCCCCEEEEEEEEEEECCCEEEEEECCCCCCEEEEEEEECCCCCEEEEEHHHHHHHH
IHQNCQHFQVNNVHIVLGEAPTALNNLPDPHRIFIGGSGGHLQEILNYCQMRLDLSGVIV
HHCCCCEEEECCEEEEECCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEE
VSLATLENFYIATQWFDKPNWVVEHLQIQLSRSVPVASMTRLTPLNPVMLIRASRNPN
EEEEHHCCEEEEEEECCCCCHHEEEHEEEECCCCCHHHHHCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]