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The map label for this gene is holA [H]

Identifier: 158336795

GI number: 158336795

Start: 3719353

End: 3720372

Strand: Reverse

Name: holA [H]

Synonym: AM1_3663

Alternate gene names: 158336795

Gene position: 3720372-3719353 (Counterclockwise)

Preceding gene: 158336798

Following gene: 158336794

Centisome position: 57.2

GC content: 47.55

Gene sequence:

>1020_bases
ATGCCCGTTTATCTCTTCTGGGGAGAAGATACTTATCGCTTATCGAAAGCAGTTCAGGCCCTTCATCAAGAGGTCTTAGA
TCCAGAGTGGCTAAGCTTCAACCTGGATAAAATAGATGTCGCTTCTGGATCCGATGGCACCGCATCGGTGATTCAAGGTC
TGAATCAAGTGATGACGCCACCGTTTGGATTAGGGCATCGTTTGGTCTGGTTAACGAATCCCTTAGTAGGAGCCACAGCC
GATCTGCTACCCGAATTTGAACGCACCCTCCCCGATTTACCCCCCACATCCCACTTGTTATTAACTCAAACTACCAAACC
GGATGGTCGTAGCAAGCTGACAAAATTATTACAAAAACAGGCTCAAGTGACTGAGTTTGCCCTCATTCCTCCTTGGAAGA
CCGCTCAGATTTTGCAAATGGTCAAACGGGCAGCCCATGATTTGGAGGTTCCGTTAACCCAAGCGGCTGGAGAACAACTT
GCCGATGCAGTGGGTAACGATACCCGTCGTCTCTATGGAGAGCTAGAGAAATTAAAGCTATATTCCTTATCTTCAGATGC
CCAAAACAACACCAAACGGATCGGTCTAGAGATCGTTCAGCATTTAGTCTCCTCCACGACTCAAAACAGTTTGCAGTTAG
CTGAAACTATTCGCCAAGGGCAAACCGATCAAGCCTTGGGATTAGTCGCTGAGTTACTGAACTTGAATGAACCTGGCTTA
AAAATTGTCGCGACCCTGATACGGCAATTTCGGACTTGGCTATGGGTCAAACTGATGGTGGTCTCAGGCGAACAGGACGA
ACGGGTCATTGCTCGCGCCGCAGAAGTGGGTAATCCCAAACGCATCTATTTTCTCAAACAAGCCGTCCAAACCGTGACAT
GTCAGCAACTTCGTCAATCCCTATCTTGTCTCTTAGATTTGGAAGTTGCCCTGAAGCAAGGCGAAGCCCCCCGCTCAACT
TTAATCACTACTGTGGTTGAGATGAGTCACATTTGCCAAGCTAATCCAATCTTGTCTTAA

Upstream 100 bases:

>100_bases
ATAGCTGTCGACTCTCCAAAAAAGGGCATCCTAACCAAACCACAAGATCGCTTTGTTGCCCTAACACTATTCATAATGTG
AGTAGTCACACCAGCTTGCT

Downstream 100 bases:

>100_bases
GACTATCAGGGAGAGAGGAATCGAATCCCTTGAGTTTGCTTCAATCGATCTGTAATTCCACCAATGTTGGAACTTCCCCA
GAAAAAATGATTCAAGATAG

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MPVYLFWGEDTYRLSKAVQALHQEVLDPEWLSFNLDKIDVASGSDGTASVIQGLNQVMTPPFGLGHRLVWLTNPLVGATA
DLLPEFERTLPDLPPTSHLLLTQTTKPDGRSKLTKLLQKQAQVTEFALIPPWKTAQILQMVKRAAHDLEVPLTQAAGEQL
ADAVGNDTRRLYGELEKLKLYSLSSDAQNNTKRIGLEIVQHLVSSTTQNSLQLAETIRQGQTDQALGLVAELLNLNEPGL
KIVATLIRQFRTWLWVKLMVVSGEQDERVIARAAEVGNPKRIYFLKQAVQTVTCQQLRQSLSCLLDLEVALKQGEAPRST
LITTVVEMSHICQANPILS

Sequences:

>Translated_339_residues
MPVYLFWGEDTYRLSKAVQALHQEVLDPEWLSFNLDKIDVASGSDGTASVIQGLNQVMTPPFGLGHRLVWLTNPLVGATA
DLLPEFERTLPDLPPTSHLLLTQTTKPDGRSKLTKLLQKQAQVTEFALIPPWKTAQILQMVKRAAHDLEVPLTQAAGEQL
ADAVGNDTRRLYGELEKLKLYSLSSDAQNNTKRIGLEIVQHLVSSTTQNSLQLAETIRQGQTDQALGLVAELLNLNEPGL
KIVATLIRQFRTWLWVKLMVVSGEQDERVIARAAEVGNPKRIYFLKQAVQTVTCQQLRQSLSCLLDLEVALKQGEAPRST
LITTVVEMSHICQANPILS
>Mature_338_residues
PVYLFWGEDTYRLSKAVQALHQEVLDPEWLSFNLDKIDVASGSDGTASVIQGLNQVMTPPFGLGHRLVWLTNPLVGATAD
LLPEFERTLPDLPPTSHLLLTQTTKPDGRSKLTKLLQKQAQVTEFALIPPWKTAQILQMVKRAAHDLEVPLTQAAGEQLA
DAVGNDTRRLYGELEKLKLYSLSSDAQNNTKRIGLEIVQHLVSSTTQNSLQLAETIRQGQTDQALGLVAELLNLNEPGLK
IVATLIRQFRTWLWVKLMVVSGEQDERVIARAAEVGNPKRIYFLKQAVQTVTCQQLRQSLSCLLDLEVALKQGEAPRSTL
ITTVVEMSHICQANPILS

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:
GO:0003677: DNA polymerase III, delta subunit
GO:0003887: DNA polymerase III, delta subunit
GO:0006260: DNA polymerase III, delta subunit
GO:0009360: DNA polymerase III, delta subunit

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 37612; Mature: 37481

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVYLFWGEDTYRLSKAVQALHQEVLDPEWLSFNLDKIDVASGSDGTASVIQGLNQVMTP
CCEEEEECCCHHHHHHHHHHHHHHHCCCCHHEECCCEEEECCCCCCHHHHHHHHHHHCCC
PFGLGHRLVWLTNPLVGATADLLPEFERTLPDLPPTSHLLLTQTTKPDGRSKLTKLLQKQ
CCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
AQVTEFALIPPWKTAQILQMVKRAAHDLEVPLTQAAGEQLADAVGNDTRRLYGELEKLKL
HHHHHEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHE
YSLSSDAQNNTKRIGLEIVQHLVSSTTQNSLQLAETIRQGQTDQALGLVAELLNLNEPGL
EECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHH
KIVATLIRQFRTWLWVKLMVVSGEQDERVIARAAEVGNPKRIYFLKQAVQTVTCQQLRQS
HHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LSCLLDLEVALKQGEAPRSTLITTVVEMSHICQANPILS
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PVYLFWGEDTYRLSKAVQALHQEVLDPEWLSFNLDKIDVASGSDGTASVIQGLNQVMTP
CEEEEECCCHHHHHHHHHHHHHHHCCCCHHEECCCEEEECCCCCCHHHHHHHHHHHCCC
PFGLGHRLVWLTNPLVGATADLLPEFERTLPDLPPTSHLLLTQTTKPDGRSKLTKLLQKQ
CCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
AQVTEFALIPPWKTAQILQMVKRAAHDLEVPLTQAAGEQLADAVGNDTRRLYGELEKLKL
HHHHHEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHE
YSLSSDAQNNTKRIGLEIVQHLVSSTTQNSLQLAETIRQGQTDQALGLVAELLNLNEPGL
EECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHH
KIVATLIRQFRTWLWVKLMVVSGEQDERVIARAAEVGNPKRIYFLKQAVQTVTCQQLRQS
HHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LSCLLDLEVALKQGEAPRSTLITTVVEMSHICQANPILS
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]