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The map label for this gene is mpgP [H]

Identifier: 158336782

GI number: 158336782

Start: 3706843

End: 3707670

Strand: Direct

Name: mpgP [H]

Synonym: AM1_3650

Alternate gene names: 158336782

Gene position: 3706843-3707670 (Clockwise)

Preceding gene: 158336781

Following gene: 158336783

Centisome position: 57.0

GC content: 51.69

Gene sequence:

>828_bases
ATGACTAACTCGGCGTCTTATTTGGTTTTTACAGACTTAGATGGCACGCTTCTCAATCATGATGATTACCGATATGATGA
TGCGTTGCCGATGCTGGCCTGGTTAAAAGATCATCAGATTCCAGTCATTGCCGTGACTAGTAAAACACGGGTCGAAGTGG
AGGAGCTGCTGCAAGCCCTCTCGTTTGAGGAGCCCTTTGTGGTGGAGAATGGTAGCGGTGTCTTTATTCCCCACAATGAT
CAGCGCTTTGATCTCTCCCACACAGATATTGCCCAGCAGGAACAGCATCAGCGCTTGTCTTTGGGATGTACCTATGATCA
GGCTAGAACCGGCCTCAAAACCCTGTCCCAGTGCCTGAGTCAGCCGCTCCAAGGTTTTGGGGATATGACGGTGGATGAGT
TAATTGCTTTAACCGGCCTCAGCACAGATGATGCGCTTAAAGCCCAAACCCGCGAGTTTACGGAGCCCTTTGTTAATCCA
GGACTAGACGCTAAAGCATTAGAACAGCATGTGGCTGAGATCGGGTTCCAGGTTTTGGTGGGCGATCGCTTCTGCCATTT
GATTGGAGTAGGGGCGGGCAAGGGTAAAGCGGTCGATCTTTTGGTGCAGTGCTATCAAGCGCCTCAGGGACCCGTTAAGA
CCGTAGGACTGGGAAATAGTCCTAATGATTTAGCCATGCTAGAAGTCGTCGATATTCCGATTGTGATTCCAGGCGCAAAA
GGCCCCCATCCAGGATTAGCGGGTCGAGGGTGGCAGATCGCACCCGCTACAGGTGCCAAGGGGTGGGCGATGGCAATGCA
ACAGGTGCGTGATCAGTTTTGGGGGTAG

Upstream 100 bases:

>100_bases
ACTTTGCTCTTGAACCCCTATCAATCCCTATGGATTACGAATAAGTTTGAAGGTCTAGAAGCCGATGGGCAAACCTGTCA
CTTAGAAGTCGAAGGAGACG

Downstream 100 bases:

>100_bases
GGATTGCGGGCGTCTTTGAGAGACAGCCTTACCAATTCTGAGAGCTGTTCATGGAGTTCTTATCGTTTCCTCAGATACGG
GTTGGGATAGCCTCAGTCAC

Product: mannosyl-3-phosphoglycerate phosphatase

Products: NA

Alternate protein names: MPGP [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTNSASYLVFTDLDGTLLNHDDYRYDDALPMLAWLKDHQIPVIAVTSKTRVEVEELLQALSFEEPFVVENGSGVFIPHND
QRFDLSHTDIAQQEQHQRLSLGCTYDQARTGLKTLSQCLSQPLQGFGDMTVDELIALTGLSTDDALKAQTREFTEPFVNP
GLDAKALEQHVAEIGFQVLVGDRFCHLIGVGAGKGKAVDLLVQCYQAPQGPVKTVGLGNSPNDLAMLEVVDIPIVIPGAK
GPHPGLAGRGWQIAPATGAKGWAMAMQQVRDQFWG

Sequences:

>Translated_275_residues
MTNSASYLVFTDLDGTLLNHDDYRYDDALPMLAWLKDHQIPVIAVTSKTRVEVEELLQALSFEEPFVVENGSGVFIPHND
QRFDLSHTDIAQQEQHQRLSLGCTYDQARTGLKTLSQCLSQPLQGFGDMTVDELIALTGLSTDDALKAQTREFTEPFVNP
GLDAKALEQHVAEIGFQVLVGDRFCHLIGVGAGKGKAVDLLVQCYQAPQGPVKTVGLGNSPNDLAMLEVVDIPIVIPGAK
GPHPGLAGRGWQIAPATGAKGWAMAMQQVRDQFWG
>Mature_274_residues
TNSASYLVFTDLDGTLLNHDDYRYDDALPMLAWLKDHQIPVIAVTSKTRVEVEELLQALSFEEPFVVENGSGVFIPHNDQ
RFDLSHTDIAQQEQHQRLSLGCTYDQARTGLKTLSQCLSQPLQGFGDMTVDELIALTGLSTDDALKAQTREFTEPFVNPG
LDAKALEQHVAEIGFQVLVGDRFCHLIGVGAGKGKAVDLLVQCYQAPQGPVKTVGLGNSPNDLAMLEVVDIPIVIPGAKG
PHPGLAGRGWQIAPATGAKGWAMAMQQVRDQFWG

Specific function: Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG). The enzyme is absolutely specific for MPG [H]

COG id: COG3769

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:
GO:0003824: Mannosyl-3-phosphoglycerate phosphatase
GO:0005737: Mannosyl-3-phosphoglycerate phosphatase
GO:0008152: Mannosyl-3-phosphoglycerate phosphatase
GO:0016787: Mannosyl-3-phosphoglycerate phosphatase
GO:0050531: Mannosyl-3-phosphoglycerate phosphatase

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MPGP family [H]

Homologues:

Organism=Escherichia coli, GI1788265, Length=235, Percent_Identity=30.2127659574468, Blast_Score=103, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR006381
- InterPro:   IPR012813 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.70 [H]

Molecular weight: Translated: 29922; Mature: 29791

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSASYLVFTDLDGTLLNHDDYRYDDALPMLAWLKDHQIPVIAVTSKTRVEVEELLQAL
CCCCCCEEEEECCCCEEECCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHH
SFEEPFVVENGSGVFIPHNDQRFDLSHTDIAQQEQHQRLSLGCTYDQARTGLKTLSQCLS
CCCCCEEEECCCEEEEECCCCEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
QPLQGFGDMTVDELIALTGLSTDDALKAQTREFTEPFVNPGLDAKALEQHVAEIGFQVLV
HHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCEEEEE
GDRFCHLIGVGAGKGKAVDLLVQCYQAPQGPVKTVGLGNSPNDLAMLEVVDIPIVIPGAK
CCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEECCEEECCCC
GPHPGLAGRGWQIAPATGAKGWAMAMQQVRDQFWG
CCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNSASYLVFTDLDGTLLNHDDYRYDDALPMLAWLKDHQIPVIAVTSKTRVEVEELLQAL
CCCCCEEEEECCCCEEECCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHH
SFEEPFVVENGSGVFIPHNDQRFDLSHTDIAQQEQHQRLSLGCTYDQARTGLKTLSQCLS
CCCCCEEEECCCEEEEECCCCEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
QPLQGFGDMTVDELIALTGLSTDDALKAQTREFTEPFVNPGLDAKALEQHVAEIGFQVLV
HHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCEEEEE
GDRFCHLIGVGAGKGKAVDLLVQCYQAPQGPVKTVGLGNSPNDLAMLEVVDIPIVIPGAK
CCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEECCEEECCCC
GPHPGLAGRGWQIAPATGAKGWAMAMQQVRDQFWG
CCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194; 11562374 [H]