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The map label for this gene is rfbB [C]

Identifier: 158336741

GI number: 158336741

Start: 3664642

End: 3665574

Strand: Direct

Name: rfbB [C]

Synonym: AM1_3609

Alternate gene names: 158336741

Gene position: 3664642-3665574 (Clockwise)

Preceding gene: 158336733

Following gene: 158336767

Centisome position: 56.35

GC content: 36.44

Gene sequence:

>933_bases
ATGAAGCGAGTCTTGGTAACAGGTGGAGCCGGGTTTATTGGTTCAGCTCTACTTCCTGAATTGGTTGCTTCTAATTATGA
TGTTTATGTCATCGATAATTTATCCTTTGGGAAACGAGAGCTTTTGAATATCTCAGATGATCATTTTTTCTTGTCTGATA
TTCTGGATCGGAAAAATCTAAACAGCATCATAAAGAATATTCAGCCCCATTGGGTGATTCATTTAGCTGCTATACATTTC
ATCCCCTATTGCAATCAAAACCCTTTTGAAGCCTCGAATATCAATATTCAAGGGACAATGAATATATTAGATGCACTACG
TTCATTGGATTGCTTAGAAAAAGTTCTTTTTGCCTCGACAGCAGCAGTTTATCCTAACACCAATCACCCCATTGCGGAGA
CTGTCTCTTCTAGTCCACTTGATATCTATGGATTAAGTAAATTAGCAGGAGAACATTTACTGAATGAGTTTTATCTAATG
ACCAAAATACCTAGCATTATCTGTCGATTTTTTAATGCATTTGGCGCTAGGGAAACTAATCCACACCTTATACCAGAAAT
TCATCGGCAAATTATGAATGGTAAGAGATCAATACAACTTGGTAACTTAGATCCAAAGCGGGACTTCATTCATACTGCTG
ATATGAGCCAAGCATTGCGGTTACTCTTAGAGCAATTTAGCACTGATATAGATACTTTTAATATTGGTAGTGGCCAAGAA
TATTCAGTGCAAGAGGTGGTTGAAGCATTTGAGTTAGCTATCAACGAAAAAATTCAAATTGAAGTTGATCCTGCTCGGAT
TCGTAAAGTAGAACGTCAACATCTATGTGCTGATATTTCCAAGTTAAAAGAATATATTGGTTGGAAGCCAAGAGTTGATC
TTAAGTCAGGTATTAAGTTTTTAATTGATAATCCAAACATAGCACTAGCGTAA

Upstream 100 bases:

>100_bases
GGTTGAGAGGTTAACATTAATTGCGATGTTTTCTTTCACTATATTATTTTTTCAAGGAACTACAGATAAGAGCCATAATG
CCAATGATTGGGAATAAGAT

Downstream 100 bases:

>100_bases
ATCTATTGCCCTAAGAGAATACCGTTAACATAAGAAACTAATCTCACATACCAAATGCGCTTCTAATTTTTCTGACAAAG
CAGTGCAGAATTATAGGTAA

Product: NDP-sugar dehydratase /epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKRVLVTGGAGFIGSALLPELVASNYDVYVIDNLSFGKRELLNISDDHFFLSDILDRKNLNSIIKNIQPHWVIHLAAIHF
IPYCNQNPFEASNINIQGTMNILDALRSLDCLEKVLFASTAAVYPNTNHPIAETVSSSPLDIYGLSKLAGEHLLNEFYLM
TKIPSIICRFFNAFGARETNPHLIPEIHRQIMNGKRSIQLGNLDPKRDFIHTADMSQALRLLLEQFSTDIDTFNIGSGQE
YSVQEVVEAFELAINEKIQIEVDPARIRKVERQHLCADISKLKEYIGWKPRVDLKSGIKFLIDNPNIALA

Sequences:

>Translated_310_residues
MKRVLVTGGAGFIGSALLPELVASNYDVYVIDNLSFGKRELLNISDDHFFLSDILDRKNLNSIIKNIQPHWVIHLAAIHF
IPYCNQNPFEASNINIQGTMNILDALRSLDCLEKVLFASTAAVYPNTNHPIAETVSSSPLDIYGLSKLAGEHLLNEFYLM
TKIPSIICRFFNAFGARETNPHLIPEIHRQIMNGKRSIQLGNLDPKRDFIHTADMSQALRLLLEQFSTDIDTFNIGSGQE
YSVQEVVEAFELAINEKIQIEVDPARIRKVERQHLCADISKLKEYIGWKPRVDLKSGIKFLIDNPNIALA
>Mature_310_residues
MKRVLVTGGAGFIGSALLPELVASNYDVYVIDNLSFGKRELLNISDDHFFLSDILDRKNLNSIIKNIQPHWVIHLAAIHF
IPYCNQNPFEASNINIQGTMNILDALRSLDCLEKVLFASTAAVYPNTNHPIAETVSSSPLDIYGLSKLAGEHLLNEFYLM
TKIPSIICRFFNAFGARETNPHLIPEIHRQIMNGKRSIQLGNLDPKRDFIHTADMSQALRLLLEQFSTDIDTFNIGSGQE
YSVQEVVEAFELAINEKIQIEVDPARIRKVERQHLCADISKLKEYIGWKPRVDLKSGIKFLIDNPNIALA

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=329, Percent_Identity=29.7872340425532, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI56118217, Length=329, Percent_Identity=29.7872340425532, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI189083684, Length=329, Percent_Identity=29.7872340425532, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI7657641, Length=315, Percent_Identity=26.6666666666667, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI42516563, Length=312, Percent_Identity=25.3205128205128, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4504031, Length=336, Percent_Identity=25.297619047619, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI33519455, Length=318, Percent_Identity=26.1006289308176, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI11034825, Length=319, Percent_Identity=25.0783699059561, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788353, Length=336, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786974, Length=315, Percent_Identity=28.8888888888889, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788366, Length=352, Percent_Identity=26.9886363636364, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI48994969, Length=326, Percent_Identity=28.5276073619632, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17539424, Length=341, Percent_Identity=26.9794721407625, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI133901788, Length=341, Percent_Identity=26.3929618768328, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI133901786, Length=341, Percent_Identity=26.6862170087977, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17539422, Length=341, Percent_Identity=26.3929618768328, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI133901790, Length=341, Percent_Identity=26.3929618768328, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17507723, Length=345, Percent_Identity=24.0579710144928, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17539532, Length=321, Percent_Identity=25.8566978193146, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71982035, Length=329, Percent_Identity=24.9240121580547, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17568069, Length=320, Percent_Identity=24.6875, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71982038, Length=335, Percent_Identity=24.1791044776119, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=320, Percent_Identity=20.9375, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=29.9418604651163, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21356223, Length=318, Percent_Identity=26.4150943396226, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19923002, Length=328, Percent_Identity=27.4390243902439, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24158427, Length=353, Percent_Identity=24.929178470255, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34958; Mature: 34958

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLVTGGAGFIGSALLPELVASNYDVYVIDNLSFGKRELLNISDDHFFLSDILDRKNL
CCEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHCCCHH
NSIIKNIQPHWVIHLAAIHFIPYCNQNPFEASNINIQGTMNILDALRSLDCLEKVLFAST
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
AAVYPNTNHPIAETVSSSPLDIYGLSKLAGEHLLNEFYLMTKIPSIICRFFNAFGARETN
HEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PHLIPEIHRQIMNGKRSIQLGNLDPKRDFIHTADMSQALRLLLEQFSTDIDTFNIGSGQE
CCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
YSVQEVVEAFELAINEKIQIEVDPARIRKVERQHLCADISKLKEYIGWKPRVDLKSGIKF
CCHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCEE
LIDNPNIALA
EEECCCEECC
>Mature Secondary Structure
MKRVLVTGGAGFIGSALLPELVASNYDVYVIDNLSFGKRELLNISDDHFFLSDILDRKNL
CCEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHCCCHH
NSIIKNIQPHWVIHLAAIHFIPYCNQNPFEASNINIQGTMNILDALRSLDCLEKVLFAST
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
AAVYPNTNHPIAETVSSSPLDIYGLSKLAGEHLLNEFYLMTKIPSIICRFFNAFGARETN
HEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PHLIPEIHRQIMNGKRSIQLGNLDPKRDFIHTADMSQALRLLLEQFSTDIDTFNIGSGQE
CCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
YSVQEVVEAFELAINEKIQIEVDPARIRKVERQHLCADISKLKEYIGWKPRVDLKSGIKF
CCHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCEE
LIDNPNIALA
EEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]