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The map label for this gene is sglT [H]

Identifier: 158336606

GI number: 158336606

Start: 3507719

End: 3509194

Strand: Direct

Name: sglT [H]

Synonym: AM1_3472

Alternate gene names: 158336606

Gene position: 3507719-3509194 (Clockwise)

Preceding gene: 158336605

Following gene: 158336607

Centisome position: 53.93

GC content: 45.12

Gene sequence:

>1476_bases
ATGAGTCCAATTGATTGGGTTATCGTTGTCGCTTACGCCGTAATCGTTCTTGGGATTGGACTCTCAGCTAGTCGTAAACA
AAAGAATACAGATGAGTATTTTCGAGGTTCCAAACAATTGCCTTGGTGGGCGATTGGTATCTCAATTATTGCGACTTCCT
TCTCGGCTGCATCACTGCTGGGTGGTCCGGGAGAAGGTTACACCCATGGATTTCTCTACCTTCAGCTTCAGATTGGAGAC
CTGTTGGGATTTAGTTTAGTTATTCTGCTCTTTTTGCCATTTTTCATCCGATTGAACCTAACAACGGCTTATGAATATCT
AGAACGTCGTTTTGATGCCAAAACTCGGTCTTTGGGCTCCCTGTGCTTTATCTTATTTGTTGTTGCTCGTCTTGGAGCCT
TGCTATATGGTGCTTCCATTGTCGTTGCAACAGTTACTGCGATGCCTCTGTCCCTCGCAATTATTGTGGTGGGTTTGGCT
TCAGTGATTTATACCGTCACTGGCGGAATAACAGCCGTTGTTTGGACTGATTTTCTTCAGTTTGTGATGATTTTTGTGGG
TCTAATTGCAGGCTTATGGGCTGCTTCAATTAGTGTCCCTGGTGGTCTAGGTGCTTTGTGGATGGCGGCGGGAGAGGGAG
GTAAGCTGCAGGTGATAGATTTATCTTGGGATCCTGCCTCAGTTCGCGCTCTACCGACTGCCCTCTTTGCTTATGGTATT
CTTGCCTTTGCGGTAGCTGGCACCAATCAACAATCCGTACAGAGATACGTCTCTTGCTCAGATGTTCCGTCCGGCAGAAA
AGCAATCCTACTGGGTTGGTTTACTGGGTTTATCGGTGTTGGTGTCACATTGCTTTTGGGGGTCTTCCTCTATGGCTTCT
ATTCTCTTAATGTGGGTGCACTTCCAGAAGGGGTAGTAGGTGATCAGATTCTACCTCACTTTATTGTGAATCAAGTGCCT
CCAGTGGCTGCTGGTCTTTTGGTCGCAGCTATTTTTGCAGCAGCCATGTCGTCGATTGATTCTGCGCTTCATTCGTTAGC
AACATGCATTGTTGTGGATTTTTATCAGCGATATTCCAAGGTGAATCGAACGGATGCCCATTACTTAAAAGCGGCAAAAG
CGTGGATTATTGTGTGTGGAATTCTAGGGATTCTTTCTGCTTTTTATGTGGCTTCCACGAAAGAATCATTATTAGAATTT
TTAGTTGAATATACAGCCTTATTCTTGGGGCCCTTATTAGGTCTATTTTTAATGGGAATTCTGATTCCTCGGATTAATGC
AACCGGAGCATTTTTTGGCGTTCTTTTAGCCGCTGCTTTGCTAGCTATTGACAGTCAGCTACAATTCCTGAAATTTCCAG
GTATTTGGCGTTCCGCCATCTCAGCTCCTTTGGCTGTGATCCTCGGCTATGGTATTTCCCTCTTGGGTAAACCTCCATTG
CCGTCTTCAATCAAGGAGCTAACCTTCTGGCAATAA

Upstream 100 bases:

>100_bases
CTTAGATGCGATTTCATGAAACATAAATTTCCTTGTATCGGGACATTCTAGAGAACTGAGGATGATAGGCTATGAAAATT
GTTTTTGCAGATAATGATTT

Downstream 100 bases:

>100_bases
CATCTGTGCAGTGACAGCCTCGCCAAGGTTCGTAAATTGTGATGGTTGAAGTTTCAATGGTGGTGAAGACGCATAAACCA
TATACTGTGCTGAATGATGA

Product: sodium-coupled permease

Products: Na (I) [Cytoplasm]; pantothenate [Cytoplasm] [C]

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MSPIDWVIVVAYAVIVLGIGLSASRKQKNTDEYFRGSKQLPWWAIGISIIATSFSAASLLGGPGEGYTHGFLYLQLQIGD
LLGFSLVILLFLPFFIRLNLTTAYEYLERRFDAKTRSLGSLCFILFVVARLGALLYGASIVVATVTAMPLSLAIIVVGLA
SVIYTVTGGITAVVWTDFLQFVMIFVGLIAGLWAASISVPGGLGALWMAAGEGGKLQVIDLSWDPASVRALPTALFAYGI
LAFAVAGTNQQSVQRYVSCSDVPSGRKAILLGWFTGFIGVGVTLLLGVFLYGFYSLNVGALPEGVVGDQILPHFIVNQVP
PVAAGLLVAAIFAAAMSSIDSALHSLATCIVVDFYQRYSKVNRTDAHYLKAAKAWIIVCGILGILSAFYVASTKESLLEF
LVEYTALFLGPLLGLFLMGILIPRINATGAFFGVLLAAALLAIDSQLQFLKFPGIWRSAISAPLAVILGYGISLLGKPPL
PSSIKELTFWQ

Sequences:

>Translated_491_residues
MSPIDWVIVVAYAVIVLGIGLSASRKQKNTDEYFRGSKQLPWWAIGISIIATSFSAASLLGGPGEGYTHGFLYLQLQIGD
LLGFSLVILLFLPFFIRLNLTTAYEYLERRFDAKTRSLGSLCFILFVVARLGALLYGASIVVATVTAMPLSLAIIVVGLA
SVIYTVTGGITAVVWTDFLQFVMIFVGLIAGLWAASISVPGGLGALWMAAGEGGKLQVIDLSWDPASVRALPTALFAYGI
LAFAVAGTNQQSVQRYVSCSDVPSGRKAILLGWFTGFIGVGVTLLLGVFLYGFYSLNVGALPEGVVGDQILPHFIVNQVP
PVAAGLLVAAIFAAAMSSIDSALHSLATCIVVDFYQRYSKVNRTDAHYLKAAKAWIIVCGILGILSAFYVASTKESLLEF
LVEYTALFLGPLLGLFLMGILIPRINATGAFFGVLLAAALLAIDSQLQFLKFPGIWRSAISAPLAVILGYGISLLGKPPL
PSSIKELTFWQ
>Mature_490_residues
SPIDWVIVVAYAVIVLGIGLSASRKQKNTDEYFRGSKQLPWWAIGISIIATSFSAASLLGGPGEGYTHGFLYLQLQIGDL
LGFSLVILLFLPFFIRLNLTTAYEYLERRFDAKTRSLGSLCFILFVVARLGALLYGASIVVATVTAMPLSLAIIVVGLAS
VIYTVTGGITAVVWTDFLQFVMIFVGLIAGLWAASISVPGGLGALWMAAGEGGKLQVIDLSWDPASVRALPTALFAYGIL
AFAVAGTNQQSVQRYVSCSDVPSGRKAILLGWFTGFIGVGVTLLLGVFLYGFYSLNVGALPEGVVGDQILPHFIVNQVPP
VAAGLLVAAIFAAAMSSIDSALHSLATCIVVDFYQRYSKVNRTDAHYLKAAKAWIIVCGILGILSAFYVASTKESLLEFL
VEYTALFLGPLLGLFLMGILIPRINATGAFFGVLLAAALLAIDSQLQFLKFPGIWRSAISAPLAVILGYGISLLGKPPLP
SSIKELTFWQ

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI256985183, Length=444, Percent_Identity=30.4054054054054, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI157671931, Length=447, Percent_Identity=27.7404921700224, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI4507035, Length=443, Percent_Identity=28.4424379232506, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI167466278, Length=449, Percent_Identity=27.6169265033408, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI14140236, Length=469, Percent_Identity=21.9616204690832, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4507031, Length=463, Percent_Identity=23.3261339092873, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI17941285, Length=461, Percent_Identity=22.9934924078091, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI4507033, Length=473, Percent_Identity=23.0443974630021, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI110835708, Length=544, Percent_Identity=23.7132352941176, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI206597483, Length=452, Percent_Identity=21.2389380530973, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI109659836, Length=539, Percent_Identity=22.8200371057514, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI206597487, Length=379, Percent_Identity=21.6358839050132, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI109659839, Length=555, Percent_Identity=22.1621621621622, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI87082237, Length=467, Percent_Identity=25.6959314775161, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1790113, Length=426, Percent_Identity=24.8826291079812, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1790503, Length=403, Percent_Identity=23.8213399503722, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533094, Length=467, Percent_Identity=26.7665952890792, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32566512, Length=362, Percent_Identity=24.3093922651934, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI115533096, Length=330, Percent_Identity=24.5454545454545, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28573698, Length=423, Percent_Identity=31.6784869976359, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24651739, Length=439, Percent_Identity=28.4738041002278, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24645928, Length=447, Percent_Identity=30.4250559284116, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI221459588, Length=444, Percent_Identity=29.0540540540541, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI221459586, Length=450, Percent_Identity=28.2222222222222, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24651741, Length=431, Percent_Identity=27.8422273781903, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI221459584, Length=427, Percent_Identity=27.8688524590164, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24650192, Length=444, Percent_Identity=26.1261261261261, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24640370, Length=430, Percent_Identity=30, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281362054, Length=428, Percent_Identity=27.1028037383178, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI281362052, Length=428, Percent_Identity=27.1028037383178, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI281362050, Length=428, Percent_Identity=27.1028037383178, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24648056, Length=428, Percent_Identity=27.1028037383178, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21356827, Length=428, Percent_Identity=27.1028037383178, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24641117, Length=456, Percent_Identity=28.0701754385965, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI281362918, Length=438, Percent_Identity=27.8538812785388, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI19920916, Length=427, Percent_Identity=31.1475409836066, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI221459582, Length=440, Percent_Identity=29.5454545454545, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI161076631, Length=417, Percent_Identity=29.2565947242206, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI221379702, Length=463, Percent_Identity=25.9179265658747, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI28574994, Length=457, Percent_Identity=26.4770240700219, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281364280, Length=441, Percent_Identity=23.3560090702948, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 52400; Mature: 52268

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIDWVIVVAYAVIVLGIGLSASRKQKNTDEYFRGSKQLPWWAIGISIIATSFSAASLL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
GGPGEGYTHGFLYLQLQIGDLLGFSLVILLFLPFFIRLNLTTAYEYLERRFDAKTRSLGS
CCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCFILFVVARLGALLYGASIVVATVTAMPLSLAIIVVGLASVIYTVTGGITAVVWTDFLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FVMIFVGLIAGLWAASISVPGGLGALWMAAGEGGKLQVIDLSWDPASVRALPTALFAYGI
HHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
LAFAVAGTNQQSVQRYVSCSDVPSGRKAILLGWFTGFIGVGVTLLLGVFLYGFYSLNVGA
HHHHHCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPEGVVGDQILPHFIVNQVPPVAAGLLVAAIFAAAMSSIDSALHSLATCIVVDFYQRYSK
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNRTDAHYLKAAKAWIIVCGILGILSAFYVASTKESLLEFLVEYTALFLGPLLGLFLMGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIPRINATGAFFGVLLAAALLAIDSQLQFLKFPGIWRSAISAPLAVILGYGISLLGKPPL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCCCC
PSSIKELTFWQ
CHHHHHHCCCC
>Mature Secondary Structure 
SPIDWVIVVAYAVIVLGIGLSASRKQKNTDEYFRGSKQLPWWAIGISIIATSFSAASLL
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
GGPGEGYTHGFLYLQLQIGDLLGFSLVILLFLPFFIRLNLTTAYEYLERRFDAKTRSLGS
CCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCFILFVVARLGALLYGASIVVATVTAMPLSLAIIVVGLASVIYTVTGGITAVVWTDFLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FVMIFVGLIAGLWAASISVPGGLGALWMAAGEGGKLQVIDLSWDPASVRALPTALFAYGI
HHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
LAFAVAGTNQQSVQRYVSCSDVPSGRKAILLGWFTGFIGVGVTLLLGVFLYGFYSLNVGA
HHHHHCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPEGVVGDQILPHFIVNQVPPVAAGLLVAAIFAAAMSSIDSALHSLATCIVVDFYQRYSK
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNRTDAHYLKAAKAWIIVCGILGILSAFYVASTKESLLEFLVEYTALFLGPLLGLFLMGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIPRINATGAFFGVLLAAALLAIDSQLQFLKFPGIWRSAISAPLAVILGYGISLLGKPPL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCCCC
PSSIKELTFWQ
CHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; pantothenate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + pantothenate [Periplasm] = Na (I) [Cytoplasm] + pantothenate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]